Abstract: The presently described technology provides compositions comprising aryl carboxylic acids and, for example NSAIDs, chemically conjugated to oxycodone (4,5-?-epoxy-14-hydroxy-17-methylmorphinan-6-one) to form novel prodrugs/compositions of oxycodone, including benzoates, salicylates, propionates, fenamates, and acetates, which have a decreased potential for abuse of oxycodone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology.

Abstract: A method for regulating parameters of at least two bioreactor bags individually, which bioreactor bags are provided on one and the same rocking part of a bioreactor system. The method includes the steps of: determining an individual weight of the content in each bioreactor bag at different points in time during processing; regulating one or more parameters in each bioreactor bag in dependence of the individual weights.

Abstract: The presently described technology provides compositions comprising aryl carboxylic acids and, for example NSAIDs, chemically conjugated to oxymorphone (4,5-?-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one) to form novel prodrugs/compositions of oxymorphone, including benzoates, salicylates, propionates, fenamates, and acetates, which have a decreased potential for abuse of oxymorphone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology.

Abstract: A semiconductor device includes a first test structure including a first portion of a conductive structure and a second portion of the conductive structure located within a first lateral wiring layer of a layer stack of the semiconductor device. The first portion of the conductive structure of the first test structure is electrically connected to the second portion of the conductive structure of the first test structure through a third portion located within a second lateral wiring layer of the layer stack arranged above the first lateral wiring layer. Further, the first portion of the conductive structure of the first test structure is electrically connected to a gate of a test transistor structure, a doping region of the test transistor structure or an electrode of a test capacitor. Additionally, the first portion of the conductive structure of the first test structure is electrically connected to a first test pad of the first test structure.

Abstract: Semiconductor devices and methods of manufacture thereof are disclosed. In one embodiment, a semiconductor device includes an array having at least one first region and at least one second region. The first region includes at least one first device oriented in a first direction. The second region includes at least one second device oriented in a second direction. The second direction is different than the first direction.

Abstract: A system and method for posture feedback can include collecting kinematic data by an activity monitoring device coupled to a user; calibrating the kinematic data to a base walking orientation of the activity monitoring device, which comprises: detecting a walking activity state through the kinematic data, and when a walking activity state is detected, generating the base walking orientation from kinematic data; setting a posture correction factor; measuring user posture with the calibrated kinematic data; triggering posture feedback based on the user posture adjusted by the posture correction factor.

Abstract: Disclosed herein is a process and an apparatus for producing coated catalysts. A process of the present disclosure includes providing a composition containing a liquid and a catalytically active material and/or a precursor thereof in a stock vessel, providing a support material in a vessel which is rotatable about a longitudinal axis, transporting the composition from the stock vessel through a first conduit to a spray nozzle, transporting a propellant fluid through a second conduit to the spray nozzle, atomizing the composition and propellant fluid in the nozzle to produce an aerosol that flows into the vessel and impregnates the support material present therein, heating the vessel so the liquid present in the aerosol evaporates from the support material and the finely divided support material which has been treated with catalytically active material and/or a precursor thereof is dried, and discharging the vaporized liquid from the vessel.

Abstract: Semiconductor devices and methods of manufacture thereof are disclosed. In one embodiment, a semiconductor device includes an array having at least one first region and at least one second region. The at least one first region includes at least one first device oriented in a first direction. The at least one second region includes at least one second device oriented in a second direction. The second direction is different than the first direction.

Abstract: A system and method for utilizing an activity monitoring device that includes, during a set of initial activity sessions, collecting the kinematic data from an activity monitoring device and generating a temporal record of at least one biomechanical signal that is calculated from the kinematic data; analyzing temporal changes in the biomechanical signals during the initial activity sessions and characterizing a fatigue model; and, during a subsequent activity session collecting current kinematic data of a participant and generating at least one current biomechanical signal from the current kinematic data, monitoring the fatigue state through processing the at least one current biomechanical signal according to the fatigue model, and triggering feedback in a user interface based on the fatigue state.

Abstract: The presently described technology provides compositions comprising aryl carboxylic acids and, for example NSAIDs, chemically conjugated to oxymorphone (4,5-?-epoxy-3,14-dihydroxy-17-methylmorphinan-6-one) to form novel prodrugs/compositions of oxymorphone, including benzoates, salicylates, propionates, fenamates, and acetates, which have a decreased potential for abuse of oxymorphone. The present technology also provides methods of treating patients, pharmaceutical kits and methods of synthesizing conjugates of the present technology.

Abstract: A system and method are described herein for detecting a user's transition between sitting and standing postures. Transitions between sitting and standing states are reliably detected using an accelerometer attached to the user. By modeling error introduced by the accelerometer, and correcting for this error, transitions between sitting and standing states are reliably detected. A microprocessor coupled to the accelerometer converts the captured accelerometer data to approximate vertical acceleration. Vertical velocity, which includes accelerometer error, is determined from the approximate vertical acceleration. The vertical velocity is corrected, and the corrected vertical velocity used to determine vertical displacement. Transitions between sitting and standing states are determined from the vertical displacement.

Abstract: A system and method for customizing biomechanical wearable sensors can include a customizable biomechanical processing layer, activity model layer, and/or device communication and processing management. The system and method can include monitoring biomechanical signals at a first set of wearable sensors configured in an initial biomechanical processing configuration; selecting a configuration option for the first set of wearable sensors; delivering the configuration option to the at least one wearable sensor; and monitoring biomechanical signals according to an altered biomechanical processing configuration that is altered according to the configuration option.

Abstract: A system and method for collecting a set of kinematic data streams from an activity tracking system with at least one activity monitoring system that is attached to a user; segmenting at least a subset of the kinematic data streams into a set of segments according to actions of the user; generating a set of biomechanical signals from the kinematic data streams wherein a biomechanical signal characterize a biomechanical property during a segment and includes generating a first integration data set through data integration and baseline error correction across the set of segments of the normalized kinematic data stream and determining at least a first biomechanical signal that is at least partially based on the first integration data set; and applying the set of biomechanical signals.

Abstract: A system and method for tracking running activity that includes an activity monitor device with an inertial measurement system, a communication module, a processor configured to generate a set of biomechanical signals from kinematic data collected from the inertial measurement system, a housing that internally contains the inertial measurement system, the communication module, and the processor, and an electrical interface exposed on the external side of the housing; and a user application operable on a second computing device distinct from the activity monitor device; wherein communication and generation of biomechanical signals are operable in many modes.

Abstract: A system and method are described herein for a sensor device which biomechanically detects in real-time a user's movement state and posture and then provides real-time feedback to the user based on the user's real-time posture. The feedback is provided through immediate sensory feedback through the sensor device (e.g., a sound or vibration) as well as through an avatar within an associated application with which the sensor device communicates. The sensor device detects the user's movement state and posture by capturing data from a tri-axial accelerometer in the sensor device. Streamed data from the accelerometer is normalized to correct for sensor errors as well as variations in sensor placement and orientation. Normalization is based on accelerometer data collected while the user is wearing the device and performing specific actions.

Abstract: A system and method are described herein for detecting a user's transition between sitting and standing postures. Transitions between sitting and standing states are reliably detected using an accelerometer attached to the user. By modeling error introduced by the accelerometer, and correcting for this error, transitions between sitting and standing states are reliably detected. A microprocessor coupled to the accelerometer converts the captured accelerometer data to approximate vertical acceleration. Vertical velocity, which includes accelerometer error, is determined from the approximate vertical acceleration. The vertical velocity is corrected, and the corrected vertical velocity used to determine vertical displacement. Transitions between sitting and standing states are determined from the vertical displacement.

Abstract: In a washing element holder (2), which on one side is closed off relative to the outside(s) with a sponge material (5) having pores (4), a washing device (1) has a washing element (3) which has at least one synthetic surfactant as a foaming substance and the principal constituent.

Abstract: A system and method are described herein for a sensor device which biomechanically detects in real-time a user's movement state and posture and then provides real-time feedback to the user based on the user's real-time posture. The feedback is provided through immediate sensory feedback through the sensor device (e.g., a sound or vibration) as well as through an avatar within an associated application with which the sensor device communicates.

Abstract: A video-on-demand system including a video server storing video-on-demand content and for streaming video-on-demand through a first layer of an internet page having a first layer and a second layer; and a controller for causing there to be formed in the second layer a plurality of selectable overlay images such that a user at a location in communication with the internet remote from the video server and the controller can display streamed video-on-demand of the first layer in combination with the overlay images of the second layer and can select one of the overlay images; wherein the overlay images correspond to respective control functions for the video-on-demand stream; and the controller is responsive to selection of an overlay image to change the video-on-demand stream in accordance with the corresponding respective control function.

Abstract: A system and method are described herein for a sensor device which biomechanically detects in real-time a user's movement state and posture and then provides real-time feedback to the user based on the user's real-time posture. The feedback is provided through immediate sensory feedback through the sensor device (e.g., a sound or vibration) as well as through an avatar within an associated application with which the sensor device communicates. The sensor device detects the user's movement state and posture by capturing data from a tri-axial accelerometer in the sensor device. Streamed data from the accelerometer is normalized to correct for sensor errors as well as variations in sensor placement and orientation. Normalization is based on accelerometer data collected while the user is wearing the device and performing specific actions.