Abstract: A system receives confirmation that a vehicle has accepted automatic control imposition for a drive within a geo-fenced boundary. The system tracks travel of a plurality of vehicles, including the vehicle, within the geo-fenced boundary. The system may determine that the vehicle has a threshold likelihood of encountering at least one of another vehicle or a boundary of the geo-fence at a threshold speed or above and responsive to the determination, impose automatic control on the vehicle, including at least one of controlled braking or speed limiting.

Abstract: The present disclosure relates to polymer coatings covalently attached to the surface of a substrate and the preparation of the polymer coatings, such as poly(N-(5-azidoacetamidylpentyl)acrylamide-co-acrylamide) (PAZAM), in the formation and manipulation of substrates, such as molecular arrays and flow cells. The present disclosure also relates to methods of preparing a substrate surface by using beads coated with a covalently attached polymer, such as PAZAM, and the method of determining a nucleotide sequence of a polynucleotide attached to a substrate surface described herein.

Abstract: A vessel for the transport of liquefied gas has a hull, a cargo storage tank arranged in the hull for storing liquefied gas and an engine to propel the ship. A compressor has a compressor inlet connected to a vapour space of the at least one cargo storage tank for receiving boil-off gas at a first pressure and a compressor outlet for supplying pressurized boil-off gas to the at least one engine at a second pressure exceeding the first pressure. A boil-off gas recovery system is provided for recovery of boil off gas. The boil-off gas recovery system has a cooling section with a cooling section inlet connected to the compressor outlet to recondense at least part of the pressurized boil-off gas and a boil-off gas storage tank having a boil-off gas storage tank inlet connected to the cooling section outlet for storing the recondensed pressurized boil-off gas.

Abstract: An example of a flow cell includes a substrate; a first primer set attached to a first region on the substrate, the first primer set including an un-cleavable first primer and a cleavable second primer; and a second primer set attached to a second region on the substrate, the second primer set including a cleavable first primer and an un-cleavable second primer.

Abstract: A fuel injector includes a needle valve including a spring-retaining section and a guide section that is adjacent to the spring-retaining section. The spring-retaining section includes an elongated portion and a flange that are together configured to support a spring assembly. The guide section includes a plurality of constricted portions alternatingly arranged with a plurality of expanded portions to define an undulating shape of the guide section. Each of the plurality of expanded portions includes a plurality of indentations to permit fuel to travel therealong to exit an outlet of the fuel injector. The guide section has a length that is substantially equal to a length of the spring-retaining section.

Abstract: Systems and methods for monitoring a fleet of self-driving vehicles are disclosed. The system comprises one or more self-driving vehicles having at least one sensor for collecting current state information, a fleet-management system, and computer-readable media for storing reference data. The method comprises autonomously navigating a self-driving vehicle in an environment, collecting current state information using the vehicle's sensor, comparing the current state information with the reference data, identifying outlier data in the current state information, and generating an alert based on the outlier data. A notification based on the alert may be sent to one or more monitoring devices according to the type and severity of the outlier.

Abstract: A system to retain a bag within a container when rotated by a chute is provided. The system includes a linkage that pivots a second arm and a hook between a release position and a holding position, the linkage comprising an input, a first arm, and the second arm that supports the hook, and a fixed plate. The input is connected to a first arm such that movement of the input pivots the first arm. The second arm is pivotably connected to the first arm at a second end of the first arm, a spring is disposed at the pivotable connection between the first and second arms and is provided to bias the second arm toward a position where the second arm extends along a line that is substantially co-linear with a longitudinal axis through the first arm. The hook extends from an extended end portion of the second arm.

Abstract: An example of an array includes a support, a cross-linked epoxy polyhedral oligomeric silsesquioxane (POSS) resin film on a surface of the support, and a patterned hydrophobic polymer layer on the cross-linked epoxy POSS resin film. The patterned hydrophobic polymer layer defines exposed discrete areas of the cross-linked epoxy POSS resin film, and a polymer coating is attached to the exposed discrete areas. Another example of an array includes a support, a modified epoxy POSS resin film on a surface of the support, and a patterned hydrophobic polymer layer on the modified epoxy POSS resin film. The modified epoxy POSS resin film includes a polymer growth initiation site, and the patterned hydrophobic polymer layer defines exposed discrete areas of the modified epoxy POSS resin film. A polymer brush is attached to the polymer growth initiation site in the exposed discrete areas.

Abstract: Some embodiments described herein relate to a substrate with a surface comprising a silane or a silane derivative covalently attached to optionally substituted cycloalkene or optionally substituted heterocycloalkene for direct conjugation with a functionalized molecule of interest, such as a polymer, a hydrogel, an amino acid, a nucleoside, a nucleotide, a peptide, a polynucleotide, or a protein. In some embodiments, the silane or silane derivative contains optionally substituted norbornene or norbornene derivatives. Method for preparing a functionalized surface and the use in DNA sequencing and other diagnostic applications are also disclosed.

Abstract: An example flow cell includes a substrate having a surface. The flow cell also includes a polymeric hydrogel attached to at least a portion of the substrate surface, where the polymeric hydrogel includes a dark quencher. The flow cell further includes at least one primer set attached to the polymeric hydrogel.

Abstract: A system comprising an interface module (IM) for receiving input and generating outputs, the IM being associated with processor (17) and memory (19); a controller module (18) (CM) that is operable independently of and communicatively connected to the IM and that is associated with processor (20) and memory (22) and that receives inputs and generates outputs to control accessories wherein each memory stores a copy of a parameter list (38) and rules governing generation of the outputs, wherein each of the IM and CM is configured such that responsive to each input, the processor of the respective module IM, CM defines a state in the associated copy of the list and communicates with the other module IM, CM to cause the state to be defined in the other copy, wherein each rule requires a state to be present in the list for generation of an associated output by each module.

Abstract: A fuel injector includes an injector housing, an outlet check, an injection control valve assembly, and a valve seat orifice plate integrating a valve seat and various orifices for outlet check control. In the valve seat orifice plate a drain orifice extends between a valve seat surface and a check control chamber formed between a closing hydraulic surface of the outlet check and the valve seat orifice plate. First and second re-pressurization orifices extend between an outer surface of the valve seat orifice plate and the check control chamber.

Abstract: Embodiments of the present disclosure relate to nucleotides labeled with photoswitchable compounds. Also provided herein are methods and kits of using these labeled nucleotides for sequencing applications.

Abstract: For computing nodes having a first programmable and comprising a first node and a second node, an update of the first node from the first programmable to a second programmable across an external network is initiated. In response to the update being interrupted, the first programmable is automatically reinstated on the first node by retrieving the first programmable from the second node across an internal network. The second node is automatically updated to the second programmable by retrieving the second programmable from the first node across the internal network in response to completion of the update of the first node to the second programmable.

Abstract: A system for providing an actuated-wall visual effect in an amusement park environment, the system comprising a panel mounting frame and a panel coupled to the panel mounting frame via a damper. The system also comprises a transducer mounting frame and a transducer configured to convert an audio signal into mechanical energy. The transducer comprises a first portion coupled to the transducer frame and a second portion coupled to the panel such that the transducer is configured to oscillate the panel relative to the transducer mounting frame in response to receiving the audio signal.

Abstract: An example of a flow cell includes a substrate; a first primer set attached to a first region on the substrate, the first primer set including an un-cleavable first primer and a cleavable second primer; and a second primer set attached to a second region on the substrate, the second primer set including a cleavable first primer and an un-cleavable second primer.

Abstract: A fuel injector includes a needle valve including a spring-retaining section and a guide section that is adjacent to the spring-retaining section. The spring-retaining section includes an elongated portion and a flange that are together configured to support a spring assembly. The guide section includes a plurality of constricted portions alternatingly arranged with a plurality of expanded portions to define an undulating shape of the guide section. Each of the plurality of expanded portions includes a plurality of indentations to permit fuel to travel therealong to exit an outlet of the fuel injector. The guide section has a length that is substantially equal to a length of the spring-retaining section.

Abstract: This disclosure relates to JAK1 pathway inhibitors and their use in treating prurigo nodularis.

Abstract: An example of an array includes a support, a cross-linked epoxy polyhedral oligomeric silsesquioxane (POSS) resin film on a surface of the support, and a patterned hydrophobic polymer layer on the cross-linked epoxy POSS resin film. The patterned hydrophobic polymer layer defines exposed discrete areas of the cross-linked epoxy POSS resin film, and a polymer coating is attached to the exposed discrete areas. Another example of an array includes a support, a modified epoxy POSS resin film on a surface of the support, and a patterned hydrophobic polymer layer on the modified epoxy POSS resin film. The modified epoxy POSS resin film includes a polymer growth initiation site, and the patterned hydrophobic polymer layer defines exposed discrete areas of the modified epoxy POSS resin film. A polymer brush is attached to the polymer growth initiation site in the exposed discrete areas.

Abstract: An example of a flow cell includes a substrate and a pattern of two different silanes on at least a portion of a surface of the substrate. A first polymer is attached to a first of the two different silanes and a second polymer is attached to a second of the two different silanes. The first and second polymers respectively include a first functional group and a second functional group of a functional group pair, the functional group pair being selected from the group consisting of an activated ester functional group and an azide functional group, a tetrazine functional group and an activated ester functional group, and a tetrazine functional group and an azide functional group. A first primer set is grafted to the first polymer and a second primer set is grafted to the second polymer. The first and second primer sets are different.