Patents by Inventor Andrew S. Goldstein

Andrew S. Goldstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5695929
    Abstract: A substitute saliva standard for use in testing, calibration, and standardization of devices and methods for collecting and analyzing oral fluids.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: December 9, 1997
    Inventor: Andrew S. Goldstein
  • Patent number: 5479937
    Abstract: A device for obtaining oral fluid containing substances for testing. In one embodiment, the device includes a syringe having a plunger at the end of which an absorbent pad is attached. A test assembly containing the device is also disclosed.
    Type: Grant
    Filed: August 3, 1993
    Date of Patent: January 2, 1996
    Assignee: Epitope, Inc.
    Inventors: Thomas R. Thieme, Andrew S. Goldstein, Stephen C. Piacentini, Nanette M. Klimkow
  • Patent number: 5339829
    Abstract: A device for obtaining oral fluid containing substances for testing. In one embodiment, the device includes a syringe having a plunger at the end of which an absorbent pad is attached. A test assembly containing the device is also disclosed.
    Type: Grant
    Filed: August 25, 1992
    Date of Patent: August 23, 1994
    Assignee: Epitope, Inc.
    Inventors: Thomas R. Thieme, Andrew S. Goldstein, Stephen C. Piacentini, Nanette M. Klimkow
  • Patent number: 5335673
    Abstract: A method and device for collecting immunoglobulins and other analytes from the oral cavity for immunological and other testing. The device is a treated absorbent pad used to collect a specimen having a high concentration of immunoglobulins or other analytes. The specimen can be subjected to a basic immunological testing technique which can be used as a tool for screening a patient for diseases. A test kit is also provided.
    Type: Grant
    Filed: March 1, 1993
    Date of Patent: August 9, 1994
    Assignee: Epitope, Inc.
    Inventors: Andrew S. Goldstein, Stefan Gavojdea, David F. Zogg
  • Patent number: 5234001
    Abstract: A container for storing collected substances for subsequent testing having an open upper end adapted to be sealed with a removable stopper and a lower end having an opening communicating the interior of the container with the outside. The opening is selectively sealed by a frangible nipple during storage of the substances and unsealed for removal of the collected substances for subsequent testing. The distal end of the frangible nipple is enlarged, preferably in the form of a ball.
    Type: Grant
    Filed: April 6, 1992
    Date of Patent: August 10, 1993
    Assignee: Epitope, Inc.
    Inventors: Andrew S. Goldstein, David F. Zogg
  • Patent number: 5112758
    Abstract: A method of reducing the viscosity of a body fluid comprises mixing a body fluid with a cationic quaternary ammonium reagent. The body fluid is a mucopolysaccharide-containing body fluid which will be tested for a metabolite.
    Type: Grant
    Filed: May 9, 1988
    Date of Patent: May 12, 1992
    Assignee: Epitope, Inc.
    Inventors: Jack H. Fellman, Andrew S. Goldstein
  • Patent number: 5103836
    Abstract: A method and device for collecting immunoglobulins and other analytes from the oral cavity for immunological and other testing. The device is a treated absorbent pad used to collect a specimen having a high concentration of immunoglobulins or other analytes. The specimen can be subjected to a basic immunological testing technique which can be used as a tool for screening a patient for diseases. A test kit is also provided.
    Type: Grant
    Filed: January 15, 1991
    Date of Patent: April 14, 1992
    Assignee: Epitope, Inc.
    Inventors: Andrew S. Goldstein, Stefan Gavojdea, David F. Zogg
  • Patent number: 5073482
    Abstract: A device for testing an elastic membrane for permeability ot submicroscopic particles. The device has a first chamber to contain the particles in a fluid medium; a second chamber to contain a reagent for detecting the presence of any of the particles; suitable structure for mounting the membrane between the chambers in a fluid-tight manner so that the membrane separates the chambers; and a mechanism for applying stress to the membrane.
    Type: Grant
    Filed: June 21, 1988
    Date of Patent: December 17, 1991
    Assignee: Epitope, Inc.
    Inventor: Andrew S. Goldstein
  • Patent number: 5022409
    Abstract: The present invention is concerned with collecting immunoglobulins from the oral cavity for immunological testing. A rinse is used to collect a specimen having a high concentration of immunoglobulins. The specimen can be subjected to a basic immunological testing technique which can be used as a tool for screening a patient for diseases. A test kit is also provided for.
    Type: Grant
    Filed: September 21, 1989
    Date of Patent: June 11, 1991
    Assignee: Epitope, Inc.
    Inventors: Andrew S. Goldstein, Thomas R. Thieme, Stefan Gavojdea
  • Patent number: 4917998
    Abstract: A method is disclosed for detecting the presence of HTLV III infected cells in a medium. The method comprises contacting the medium with monoclonal antibodies against an antigen produced as a result of the infection and detecting the binding of the antibodies to the antigen. The antigen may be a gene product of the HTLV III virus or may be bound to such gene product. On the other hand the antigen may not be a viral gene product by may be produced as a result of the infection and may further be bound to a lymphocyte. The medium may be a human body fluid or a culture medium. A particular embodiment of the present method involves a method for determining the presence of an AIDS virus in a person. The method comprises combining a sample of a body fluid from the person with a monoclonal antibody that binds to an antigen produced as a result of the infection and detecting the binding of the monoclonal antibody to the antigen. The presence of the binding indicates the presence of an AIDS virus infection.
    Type: Grant
    Filed: May 6, 1986
    Date of Patent: April 17, 1990
    Assignee: Epitope, Inc.
    Inventors: Denis R. Burger, Andrew S. Goldstein
  • Patent number: 4904581
    Abstract: A method is disclosed for detecting the presence of HTLV III infected cells in a medium. The method comprises contacting the medium with monoclonal antibodies against an antigen produced as a result of the infection and detecting the binding of the antibodies to the antigen. The antigen may be a gene product of the HTLV III virus or may be bound to such gene product. On the other hand the antigen may not be a viral gene product but may be produced as a result of the infection and may further be bound to a lymphocyte. The medium may be a human body fluid or a culture medium. A particular embodiment of the present method involves a method for determining the presence of a AIDS virus in a person. The method comprises combining a sample of a body fluid from the person with a monoclonal antibody that binds to an antigen produced as a result of the infection and detecting the binding of the monoclonal antibody to the antigen. The presence of the binding indicates the presence of a AIDS virus infection.
    Type: Grant
    Filed: June 23, 1986
    Date of Patent: February 27, 1990
    Assignee: Epitope, Inc.
    Inventors: Denis R. Burger, Andrew S. Goldstein