Abstract: A method of queue design for data storage and management applies RAM data synchronization technology on many distributed nodes, both ensures storage performance and solves the problem of data loss in the system operation process; performs business separation and parallelize actions to optimize processing performance; uses simply extracted information instead of accessing the original information helps to speed up the processing ability and promptly detect events that exceed the threshold; allocates a fixed memory for the queue to ensure the safety of the whole system; in addition, provides monitoring and early warning of possible incidents. The method includes: step 1: build a deployment model; step 2: initialize the values when the application first launches; step 3: process write data to the queue; step 4: detect the threshold and process the data in the queue; step 5: remove processed data from the queue; step 6: monitor queue and early warn.

Abstract: Methods and systems are disclosed for quantizing images using machine-learning. A plurality of input images are received from a sensor (e.g., a camera), wherein each input image includes a plurality of pixels. Utilizing an image-to-image machine-learning model, each pixel is assigned a new pixel color. Utilizing a mixer machine-learning model, each new pixel color is converted to one of a fixed number of colors to produce a plurality of quantized images, with each quantized image corresponding to one of the input images. A loss function is determined based on an alignment of each input image with its corresponding quantized image via a pre-trained reference machine-learning model. One or more parameters of the image-to-image machine-learning model and the mixer model are updated based on the loss function. The process repeats, with each iteration updating the parameters of the image-to-image machine-learning model and the mixer model, until convergence, resulting in trained models.

Abstract: In some embodiments, apparatuses and methods are provided herein useful to assess monitor, improve, and/or modify health and well-being as it relates to people associated with a habitable or other built environments or spaces therein. In some embodiments, an intervention assessment system and methods include one or more sensors for measuring aspects related to the built environment, a personal user device, and a control circuit configured to receive one or more measurements form the sensor(s), identify a problem with the built environment, and identify potential interventions based on the indicators associated with the problem. By one approach, a plurality of potential interventions may be ranked based on, for example, the ability to reduce the prevalence of the problem or indicator in the built environment, feasibility, cost, and timeliness. In some approaches, the system and method also select and may implement one or more interventions.

Abstract: In some embodiments, a reconstitution or medicinal fluid delivery device includes a transfer engine including two fluidly connected spikes, each configured to pierce a container. A check valve may be disposed between the two spikes to allow unidirectional flow from one container to the other. Physical access to a fluid outlet may be obstructed by a housing until the reconstitution or medicinal fluid delivery device is actuated, whereupon physical access to the fluid outlet is permitted. The reconstitution or medicinal fluid delivery device may be placed on a flat surface and actuated with force applied in a single direction toward the flat surface.

Abstract: The invention provides methods and compositions (e.g., pharmaceutical compositions) for treating breast cancer (e.g., TNBC (e.g., eTNBC)) in a subject. In some aspects, the methods include administering a treatment regimen including a PD-1 axis binding antagonist (e.g., an anti-PD-L1 antibody (e.g., atezolizumab) or an anti-PD-1 antibody), a taxane (e.g., nab-paclitaxel or paclitaxel), an anthracycline (e.g., doxorubicin or epirubicin), and an alkylating agent (e.g., a nitrogen mustard derivative (e.g., cyclophosphamide)) to the subject. In some aspects, the treatment regimen increases the subject's likelihood of having a pathologic complete response (pCR) as compared to treatment with the taxane, the anthracycline, and the alkylating agent without the PD-1 axis binding antagonist. Also provided are pharmaceutical compositions for use in treating breast cancer (e.g., TNBC (e.g., eTNBC)) in a subject.

Abstract: The present disclosure provides an electrical power supply structure comprising a plurality of insulated pipes, each insulated pipe extending longitudinally and configured to carry high amperage electrical power, a barrier support plate comprising one or more openings for receiving the plurality of insulated pipes, the barrier support plate configured for mounting over a hole through a floor of a building, a first support structure extending longitudinally upward from an upper side of the barrier support plate, and a second support structure extending longitudinally downward from a lower side of the barrier support plate through the hole. Each of the first and second support structures comprises a longitudinally extending enclosure having a plurality of transversely extending conductor support members for supporting the plurality of insulated pipes, and the plurality of insulated pipes are grouped by phase.

Abstract: A power mesh structure for an integrated circuit is provided. A power switch cell is installed on the chip of the integrated circuit to control the switching operations of the power domain. The power meshes of the power mesh structure is specially designed. The power wires with different electrical properties are arranged in the same column or the same row to reduce the layout area of the power mesh on the material layer.

Abstract: The invention relates to a contact for a direct plug-in connector having two strips made of sheet-metal material that are arranged next to one another in an insertion portion and in a contact portion, wherein the insertion portion is provided for insertion into a through-opening, which is electrically conductive at its inner wall, in a printed circuit board and the contact portion is provided to make electrical contact with the inner wall of the through-opening, wherein the two strips are connected together in a connection portion that is provided for connecting to a cable strand, and wherein a connecting portion is located between the connection portion and the contact portion, wherein the two strips are located in a common plane and formed in an L-shaped manner in the connecting portion, wherein the legs of the connecting portion that proceed from the connection portion extend parallel to one another and the legs of the connecting portion that are connected to the contact portion extend towards one another.

Abstract: Aspects of the present disclosure relate generally to isolator devices, components thereof, and methods associated therewith for substrate processing chambers. In one implementation, a substrate processing chamber includes an isolator ring disposed between a pedestal and a pumping liner. The isolator ring includes a first surface that faces the pedestal, the first surface being disposed at a gap from an outer circumferential surface of the pedestal. The isolator ring also includes a second surface that faces the pumping liner and a protrusion that protrudes from the first surface of the isolator ring and towards the outer circumferential surface of the pedestal. The protrusion defines a necked portion of the gap between the pedestal and the isolator ring.

Abstract: A first electronic device of a local group of connected electronic devices receives a first voice command including a request for a first operation assigns a first target device from among a local group of connected electronic devices as an in-focus device for performing the first operation, causes the first operation to be performed by the first target device via operation of a server-implemented common network service, receives a second voice command including a request for a second operation and based on a determination that the second voice command does not include an explicit designation of a second target device and a determination that the second operation can be performed by the first target device, assigning the first target device.

Abstract: Variant guinea pig L-asparaginases which are truncated and humanized are described as are fusion proteins containing the L-asparaginase and use of the L-asparaginases in the treatment of cancers such as acute lymphoblastic leukemia and acute myeloid leukemia.

Abstract: A mechanical vacuum dressing comprising: a first valve layer comprising a first one-way valve; a second valve layer comprising a second one-way valve; the first valve layer being joined to the second valve layer so as to define a chamber therebetween; the first one-way valve being configured to admit fluid into the chamber through the first one-way valve but prevent fluid from exiting the chamber through the first one-way valve; the second one-way valve being configured to exhaust fluid from the chamber through the second one-way valve but prevent fluid from entering the chamber through the second one-way valve; and the second valve layer comprising an elastomeric material such that (i) when the second valve layer is moved away from the first valve layer, the volume of the chamber is increased, and (ii) when the second valve layer is thereafter released, the second valve layer moves back towards the first valve layer and the volume of the chamber is decreased.

Abstract: A method and apparatus for processing a semiconductor is disclosed herein. In one embodiment, a processing system for semiconductor processing is disclosed. The processing chamber includes two transfer chambers, a processing chamber, and a rotation module. The processing chamber is coupled to the transfer chamber. The rotation module is positioned between the transfer chambers. The rotation module is configured to rotate the substrate. The transfer chambers are configured to transfer the substrate between the processing chamber and the transfer chamber. In another embodiment, a method for processing a substrate on the apparatus is disclosed herein.

Abstract: The invention presents a system and a method for 3D human reconstruction using a compact kit of depth cameras. Instead of using complex and expensive devices as in traditional methods, the proposed system and method employs a simple, easy-to-install system to accurately collect the human body shape. The generated model is capable of moving thanks to a skeleton system simulating the human skeleton. The proposed system includes four blocks: Data Collection Block, Point Cloud Standardization Block, Human Digitization Block and Output Block. The proposed method includes five steps: Point Cloud Collecting, Point Cloud Filtering, Point Cloud Calibrating, Point Cloud Optimizing and 3D Human Model Generating.

Abstract: Apparatuses (e.g., devices, systems, etc.) and methods that may provide access to one or more tools to a remote site in the body including expandable and external working channels that may be part of a tube that is coupled to an outer surface of an elongate medical device, such as an endoscope.

Abstract: The present invention provides a method for speech separation and recognition. The present invention overcomes the disadvantages of the existing techniques by providing automatic speech recognition and separation that helps managers see what their service agents and customers are saying. From there, quickly and objectively knowing the wishes and concerns of customers as well as whether their service agents can give accurate and correct advice. In addition, the system is constantly updated based on the semi-supervised training mechanism, which means that the system can self-learn from actual data during operation, thereby helping to improve the system's accuracy.

Abstract: An electrolyte-based field effect transistor includes a dielectric layer; a source electrode and a drain electrode located on top of the dielectric layer; the electrolyte-based transistor further including an electrolyte layer between and on top of the source electrode and the drain electrode, the part of the electrolyte layer located between the source electrode and the drain electrode being in direct contact with the dielectric layer; and a gate electrode on top of the electrolyte layer, the orthogonal projection of the gate electrode in a plane including the source and drain electrodes being located, at least in part, between the source and the drain electrodes.

Abstract: Embodiments described herein relate to ground path systems providing a shorter and symmetrical path for radio frequency (RF) energy to propagate to a ground to reduce generation of the parasitic plasma. The ground path system bifurcates the processing volume of the chamber to form an inner volume that isolates an outer volume of the processing volume.

Abstract: The present disclosure generally relates to an isolation device for use in processing systems. The isolation device includes a body having a flow aperture formed therethrough. In one embodiment, the isolation device is disposed between a remote plasma source and a process chamber. A closure mechanism is pivotally disposed within the body. The closure mechanism can be actuated to enable or disable fluid communication between the remote plasma source and the process chamber. In one embodiment, the closure mechanism includes a shaft and a seal plate coupled to the shaft. A cross-arm is coupled to the shaft opposite the seal plate. The cross-arm is configured to selectively rotate the shaft and the seal plate of the closure mechanism.

Abstract: Method for manufacturing a tridimensional blood vessel model using stereolithography and optionally cell culture. Applications include surgery training, research on pathology such as SCDs and in vitro drug testing e.g. for antiplatelets. Existing models are not compatible with cell culture and cannot withstand high pressure, as opposed to the present invention. Stereolithography allows modelling of complex vessels such as carotid siphons as opposed to other existing methods.