Patents by Inventor Annette Tobia

Annette Tobia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR THE TREATMENT OF CANCER USING MEGLUMINE
    Publication number: 20190160084
    Abstract: Compositions and methods are disclosed for treating subjects with cancer, particularly skin cancer.
    Type: Application
    Filed: July 26, 2017
    Publication date: May 30, 2019
    Inventors: Annette TOBIA, Alice MARCY, Susan GILMOUR
  • Meglumine in Combination with Another Therapeutic
    Publication number: 20180271807
    Abstract: The invention relates to a method of treating or preventing a condition in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof. The invention further relates to a method of improving a physiological function in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof.
    Type: Application
    Filed: April 18, 2018
    Publication date: September 27, 2018
    Inventor: Annette Tobia
  • Methods for maintaining or improved health, well-being and/or a physiological function in a subject
    Patent number: 9974757
    Abstract: The invention relates to a method of treating or preventing a condition in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof. The invention further relates to a method of improving a physiological function in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof.
    Type: Grant
    Filed: January 24, 2017
    Date of Patent: May 22, 2018
    Assignee: Dynamics Therapeutics, Inc.
    Inventor: Annette Tobia
  • Method for treating or preventing dry eye disorders using alkylamino-polyhydroxyalkanes
    Patent number: 9861593
    Abstract: Method for the treatment or prophylaxis of dry eye disorders by the administration of alkylamino-polyhydroxyalkanes and compositions thereof.
    Type: Grant
    Filed: November 7, 2016
    Date of Patent: January 9, 2018
    Assignee: Dynamis Pharmaceuticals, Inc.
    Inventors: Alice Marcy, Annette Tobia
  • Methods for Maintaining or Improving Health, Well-Being and/or a Physiological Function in a Subject
    Publication number: 20170128386
    Abstract: The invention relates to a method of treating or preventing a condition in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof. The invention further relates to a method of improving a physiological function in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof.
    Type: Application
    Filed: January 24, 2017
    Publication date: May 11, 2017
    Inventor: Annette Tobia
  • METHOD FOR TREATING OR PREVENTING DRY EYE DISORDERS USING ALKYLAMINO-POLYHYDROXYALKANES
    Publication number: 20170049719
    Abstract: Method for the treatment or prophylaxis of dry eye disorders by the administration of alkylamino-polyhydroxyalkanes and compositions thereof.
    Type: Application
    Filed: November 7, 2016
    Publication date: February 23, 2017
    Inventors: Alice Marcy, Annette Tobia
  • Methods for maintaining or improving health, well-being and/or a physiological function in a subject
    Patent number: 9555012
    Abstract: The invention relates to a method of treating or preventing a condition in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof. The invention further relates to a method of improving a physiological function in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof.
    Type: Grant
    Filed: August 8, 2013
    Date of Patent: January 31, 2017
    Assignee: Dynamis Therapeutics, Inc.
    Inventor: Annette Tobia
  • NATURAL PRODUCT INHIBITORS OF 3DG
    Publication number: 20160331798
    Abstract: Compositions are disclosed which have as a component thereof an inhibitor of the enzymatic production of 3-deoxyglucosone (3DG) from fructoselysine and/or an inactivator of 3DG, and which are useful for the treatment or prophylaxis of a condition or disease state that is alleviated by inhibiting such 3DG production. Methods of using such compositions, e.g., for improving the appearance, texture and/or elasticity of aging skin, are also disclosed.
    Type: Application
    Filed: July 25, 2016
    Publication date: November 17, 2016
    Inventors: Annette Tobia, Alice Marcy, Bangying Su, Takeshi Niwa
  • Methods for maintaining or improving health, well-being and/or a physiological function in a subject
    Patent number: 9446007
    Abstract: The invention relates to a method of treating or preventing a condition in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof. The invention further relates to a method of improving a physiological function in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof.
    Type: Grant
    Filed: March 30, 2015
    Date of Patent: September 20, 2016
    Assignees: Dynamis Therapeutics, Inc., Lankenau Institute for Medical Research
    Inventors: Annette Tobia, Arturo Bravo Nuevo, Lisa Laury-Kleintop
  • METHODS FOR MAINTAINING OR IMPROVING HEALTH, WELL-BEING AND/OR A PHYSIOLOGICAL FUNCTION IN A SUBJECT
    Publication number: 20150202166
    Abstract: The invention relates to a method of treating or preventing a condition in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof. The invention further relates to a method of improving a physiological function in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof.
    Type: Application
    Filed: March 30, 2015
    Publication date: July 23, 2015
    Inventors: ANNETTE TOBIA, ARTURO BRAVO NUEVO, LISA LAURY-KLEINTOP
  • Methods for Maintaining or Improving Health, Well-Being and/or a Physiological Function in a Subject
    Publication number: 20140045947
    Abstract: The invention relates to a method of treating or preventing a condition in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof. The invention further relates to a method of improving a physiological function in a subject, comprising administering to the subject an acceptable composition comprising meglumine or a salt thereof.
    Type: Application
    Filed: August 8, 2013
    Publication date: February 13, 2014
    Applicant: Dynamis Therapeutics, Inc.
    Inventor: Annette Tobia
  • NATURAL PRODUCT INHIBITORS OF 3DG
    Publication number: 20130266638
    Abstract: Compositions are disclosed which have as a component thereof an inhibitor of the enzymatic production of 3-deoxyglucosone (3DG) from fructoselysine and/or an inactivator of 3DG, and which are useful for the treatment or prophylaxis of a condition or disease state that is alleviated by inhibiting such 3DG production. Methods of using such compositions, e.g., for improving the appearance, texture and/or elasticity of aging skin, are also disclosed.
    Type: Application
    Filed: June 3, 2013
    Publication date: October 10, 2013
    Inventors: Annette Tobia, Alice Marcy, Bangying Su, Takeshi Niwa
  • NATURAL PRODUCT INHIBITORS OF 3DG
    Publication number: 20120231071
    Abstract: Compositions are disclosed which have as a component thereof an inhibitor of the enzymatic production of 3-deoxyglucosone (3DG) from fructoselysine and/or an inactivator of 3DG, and which are useful for the treatment or prophylaxis of a condition or disease state that is alleviated by inhibiting such 3DG production. Methods of using such compositions, e.g., for improving the appearance, texture and/or elasticity of aging skin, are also disclosed.
    Type: Application
    Filed: May 24, 2012
    Publication date: September 13, 2012
    Inventors: Annette Tobia, Marcy Alice, Bangying Su, Takashi Niwa
  • Treatment of Inflammatory Conditions
    Publication number: 20110112188
    Abstract: The invention relates to methods of inhibiting production and function of 3-deoxyglucosone and other alpha-dicarbonyl sugars in skin thereby treating or prevention various diseases, disorders or conditions. Additionally, the invention relates to treatment of various diseases, disorders or conditions associated with or mediated by oxidative stress since 3DG induces ROS and AGEs, which are associated with the inflammatory response caused by oxidative stress.
    Type: Application
    Filed: September 9, 2010
    Publication date: May 12, 2011
    Inventors: ANNETTE TOBIA, FRANCIS KAPPLER
  • 3-Deoxyglucosone And Skin
    Publication number: 20100310482
    Abstract: The invention relates to a method of removing 3-deoxyglucosone and other alpha-dicarbonyl sugars from skin. The invention further relates to methods of inhibiting production and function of 3-deoxyglucosone and other alpha-dicarbonyl sugars in skin. The invention also relates to methods of treating 3-deoxyglucosone and other alpha-dicarbonyl sugars associated diseases and disorders of skin.
    Type: Application
    Filed: June 3, 2010
    Publication date: December 9, 2010
    Applicant: Dynamis Therapeutics, Inc.
    Inventors: Annette Tobia, Francis Kappler
  • 3-deoxyglucosone and skin
    Patent number: 7749503
    Abstract: The invention relates to a method of removing 3-deoxyglucosone and other alpha-dicarbonyl sugars from skin. The invention further relates to methods of inhibiting production and function of 3-deoxyglucosone and other alpha-dicarbonyl sugars in skin. The invention also relates to methods of treating 3-deoxyglucosone and other alpha-dicarbonyl sugars associated diseases and disorders of skin.
    Type: Grant
    Filed: June 15, 2007
    Date of Patent: July 6, 2010
    Assignee: Dynamis Therapeutics, Inc.
    Inventors: Annette Tobia, Francis Kappler
  • NATURAL PRODUCT INHIBITORS OF 3DG
    Publication number: 20100068259
    Abstract: Compositions are disclosed which have as a component thereof an inhibitor of the enzymatic production of 3-deoxyglucosone (3DG) from fructoselysine and/or an inactivator of 3DG, and which are useful for the treatment or prophylaxis of a condition or disease state that is alleviated by inhibiting such 3DG production. Methods of using such compositions, e.g., for improving the appearance, texture and/or elasticity of aging skin, are also disclosed.
    Type: Application
    Filed: May 29, 2009
    Publication date: March 18, 2010
    Inventors: Annette Tobia, Marcy Alice, Bangying Su, Takeshi Niwa
  • 3-deoxyglucosone and skin
    Patent number: 7671019
    Abstract: The invention relates to the discovery that 3-deoxyglucosone (3DG) and other alpha-dicarbonyl sugars associated diseases and disorders are present and produced in the skin. Further, the invention relates to the discovery that amadorase, an enzyme that mediates 3DG synthesis, is also present in the skin. Thus, the invention further relates to methods of inhibiting production and function of 3-deoxyglucosone and other alpha-dicarbonyl sugars in skin thereby treating or prevention various diseases, disorders or conditions. Additionally, the invention relates to treatment of various diseases, disorders or conditions associated with or mediated by oxidative stress since 3DG induces ROS and AGEs, which are associated with the inflammatory response caused by oxidative stress.
    Type: Grant
    Filed: October 15, 2004
    Date of Patent: March 2, 2010
    Assignee: Dynamis Therapeutics, Inc.
    Inventors: Annette Tobia, Francis Kappler
  • 3-deoxyglucosone and skin
    Patent number: 7622117
    Abstract: The invention relates to a method of removing 3-deoxyglucosone and other alpha-dicarbonyl sugars from skin. The invention further relates to methods of inhibiting production and function of 3-deoxyglucosone and other alpha-dicarbonyl sugars in skin. The invention also relates to methods of treating 3-deoxyglucosone and other alpha-dicarbonyl sugars associated diseases and disorders of skin.
    Type: Grant
    Filed: July 18, 2002
    Date of Patent: November 24, 2009
    Assignee: Dynamis Therapeutics, Inc.
    Inventors: Annette Tobia, Francis Kappler
  • 3-Deoxyglucosone and skin
    Publication number: 20080292568
    Abstract: The invention relates to a method of removing 3-deoxyglucosone and other alpha-dicarbonyl sugars from skin. The invention further relates to methods of inhibiting production and function of 3-deoxyglucosone and other alpha-dicarbonyl sugars in skin. The invention also relates to methods of treating 3-deoxyglucosone and other alpha-dicarbonyl sugars associated diseases and disorders of skin.
    Type: Application
    Filed: June 15, 2007
    Publication date: November 27, 2008
    Applicant: Dynamis Therapeutics, Inc.
    Inventors: Annette Tobia, Francis Kappler