Abstract: Systems and techniques are directed to a Swappable Retractable Tool Tip (SRTT), which is designed as a next generation of friction stir welding tools and retractable tool tips. The disclosed SRTT may be “swappable,” having different types of retractable tool tips that can be assembled and employed as a part of the SRTT. A SRTT system can include at least: a blank tool holder, a piston, and a retractable tool tip. In operation, the blank tool holder allows air to flow to cause movement of the piston and the retractable tool tip. For example, compressed air can push up on the piston and the retractable tool tip, retracting it into a “home” position inside of the blank tool holder. Also, the SRTT can include springs that push down on the piston and the retractable tool tip, extending the tip into an “extended” position outside of the blank tool holder.

Abstract: A portable data collection device includes a FT-NIR spectrometer operable with a direct current (DC) power input, a hand-held probe having a large sampling area, a portable computer operable with a DC power input and configured for operation of the FT-NIR spectrometer; and a portable electric power source for providing a DC power output. The components of the portable data collection device are contained within a portable carrier. The portable data collection device is used onsite to obtain a spectra from a material sample. The spectra is sent by the portable computer of the portable data collection device to a remote computer/server. Application methods stored in a remote database analyze the spectra to obtain desired trait results for the material sample. The obtained results are stored on a remote database and can be displayed on a screen of an on-site mobile device.

Abstract: Systems and techniques are directed to a Swappable Retractable Tool Tip (SRTT), which is designed as a next generation of friction stir welding tools and retractable tool tips. The disclosed SRTT may be “swappable,” having different types of retractable tool tips that can be assembled and employed as a part of the SRTT. A SRTT system can include at least: a blank tool holder, a piston, and a retractable tool tip. In operation, the blank tool holder allows air to flow to cause movement of the piston and the retractable tool tip. For example, compressed air can push up on the piston and the retractable tool tip, retracting it into a “home” position inside of the blank tool holder. Also, the SRTT can include springs that push down on the piston and the retractable tool tip, extending the tip into an “extended” position outside of the blank tool holder.

Abstract: A thermally assisted magnetic head including a main magnetic pole layer having a magnetic pole end face arranged in a medium-opposing surface, a near-field transducer which generates a near-field light for heating the magnetic recording medium, a waveguide guiding light to the near-field transducer; and an optical side shield being arranged in the medium-opposing surface side of the waveguide and being formed so as to sandwich a part of the near-field transducer, in the medium-opposing surface side, from both sides of a direction along the medium-opposing surface. The near-field transducer includes a protruding end-part (PEG). Then the protruding end-part is arranged to have a PEG end-surface at a position receded from the medium-opposing surface.

Abstract: A system for transition curvature improvement on thermally assisted magnetic recording, includes: an energy source, a thermally assisted magnetic recording head including a magnetic main pole for writing of a thermally assisted magnetic recording medium, a waveguide for directing an energy produced by the energy source, and a PPG including a peg and adjacent to the waveguide, the PPG being for turning the energy into a surface plasmon which travels down the peg to heat the thermally assisted magnetic recording medium. The magnetic main pole includes a first portion enabling a first magnetic field strength and at least one additional portion enabling a magnetic field strength stronger than the first magnetic field strength such that a magnetic field of the magnetic main pole along a horizontal direction thereof enables generation of a substantially straight transition curve while writing on the thermally assisted magnetic recording medium.

Abstract: In accordance with an embodiment, described herein is a system and method for providing a work manager for use in an application server environment. In accordance with an embodiment, a system administrator can configure a partition work manager to provide partition work request prioritization (fair share value) to each partition within a multitenant application server environment. The system administrator can additionally configure the partition work manager to impose a minimum threads constraint limit, a partition capacity constraint, and/or a partition maximum threads constraint, all of which restrict the use of thread resources by the partitions within the environment.

Abstract: In accordance with an embodiment, described herein is a system and method for providing a work manager for use in an application server environment. In accordance with an embodiment, a system administrator can configure a partition work manager to provide partition work request prioritization (fair share value) to each partition within a multitenant application server environment. The system administrator can additionally configure the partition work manager to impose a minimum threads constraint limit, a partition capacity constraint, and/or a partition maximum threads constraint, all of which restrict the use of thread resources by the partitions within the environment.

Abstract: A nucleic acid sequence, including an isolated, purified or recombinant nucleic acid sequence, includes: (a) a nucleic acid sequence encoding a polypeptide for stimulating embryonic development, namely, a PLC-zeta; PLC? amino acid sequence, capable of triggering calcium oscillations in oocytes; (b) a sequence substantially homologous to or that hybridizes to sequence (a) under stringent conditions; (c) a sequence substantially homologous to or that hybridizes to the sequences (a) or (b) but for degeneracy of the genetic code; and (d) an oligonucleotide specific for any of the sequences (a), (b) or (c) above.

Abstract: The present invention provides compounds of Formula (I) that act as glucokinase activators; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by glucokinase.

Abstract: A nucleic acid sequence, including an isolated, purified or recombinant nucleic acid sequence, includes: (a) a nucleic acid sequence encoding a polypeptide encompassed by the present invention, namely, a PLC-zeta; PLC? amino acid sequence, capable of triggering calcium oscillations in oocytes; (b) a sequence substantially homologous to or that hybridizes to sequence (a) under stringent conditions; (c) a sequence substantially homologous to or that hybridizes to the sequences (a) or (b) but for degeneracy of the genetic code; and (d) an oligonucleotide specific for any of the sequences (a), (b) or (c) above.

Abstract: The present invention provides compounds of Formula (I) that act as glucokinase activators; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by glucokinase.

Abstract: The present invention provides compounds of Formula (I) that act as glucokinase activators; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by glucokinase.

Abstract: A method of delaying the onset of a backward wave mode in a frequency selective surface having a two dimensional array of conductive patches or elements and an RF ground plane, the two dimensional array of patches or elements being interconnected by variable capacitors, the method comprising separating grounds associated with the variable capacitors from the RF ground plane and providing a separate conductive mesh structure or arrangement as a bias voltage ground for the variable capacitors. A tunable impedance surface comprises a RF ground plane; a plurality of patches or elements disposed in an array a distance from the ground plane; a capacitor arrangement for controllably varying capacitance between at least selected ones of adjacent patches or elements in the array; and a grounding mesh associated with the capacitor arrangement for providing a control voltage ground to capacitors in the capacitor arrangement, the grounding mesh being spaced from the RF ground plane by dielectric material.

Abstract: The present invention relates to a compound of formula (I): or a pharmaceutically acceptable salt or solvate thereof, wherein: Ring A is (4-12)-membered heterocyclyl; Ring B is a fused benzene ring selected from the group consisting of: Ring A, ring B, ring C, R1, R1a, R2, R3, R4, L2, n, t, w, and z are as defined in the specification. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and methods of treating a condition that is mediated by the modulation of glucokinase, the method comprising administering to a mammal an effective amount of a compound of formula (I).

Abstract: Dual-band and multi-band radiating elements are described based on composite right/left-handed (CRLH) meta-material transmission line (TL). These elements can operate as resonators and/or antennas depending on feed-line configuration. The radiating elements are based on the fundamental backward wave supported by a composite right/left-handed (CRLH) meta-material transmission line (TL). Unit-cells of the transmission line comprise conductive patches coupled through vias to a ground plane. The physical size and operational frequencies of the radiating element is determined by the unit cell of the CRLH meta-material. This radiating element is configured for monopolar radiation at a first resonant frequency and patch-like radiation at a second resonant frequency. The first and second resonant frequencies are not constrained to a harmonic relationship.

Abstract: The present invention relates to a compound of formula (I): or a pharmaceutically acceptable salt or solvate thereof, wherein: Ring A is (4-12)-membered heterocyclyl; Ring B is a fused benzene ring selected from the group consisting of: Ring A, ring B, ring C, R1, R1a, R2, R3, R4, L2, n, t, w, and z are as defined in the specification. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and methods of treating a condition that is mediated by the modulation of glucokinase, the method comprising administering to a mammal an effective amount of a compound of formula (I).

Abstract: The present invention relates to a compound of formula (I): or a pharmaceutically acceptable salt or solvate thereof, wherein: Ring A is (4-12)-membered heterocyclyl; Ring B is a fused benzene ring selected from the group consisting of: Ring A, ring B, ring C, R1, R1a, R2, R3, R4, L2, n, t, w, and z are as defined in the specification. The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) and methods of treating a condition that is mediated by the modulation of glucokinase, the method comprising administering to a mammal an effective amount of a compound of formula (I).

Abstract: The present invention provides compounds of Formula (I) that act as glucokinase activators; pharmaceutical compositions thereof; and methods of treating diseases, disorders, or conditions mediated by glucokinase.

Abstract: A system and method for prefabricating information pages is disclosed, in which the necessary steps to retrieve and package information requested by a user are preemptively performed by the computer system. When the user later makes an explicit request for information, the desired information can be immediately displayed to the user without the delays associated with contemporaneous retrieval and packaging of the information. The prefabrication system of the invention can be configured to automatically tune its processing to the changing conditions that exist in the computer system, which can be used to maximize use of available system resources. The present invention can be scalably deployed to perform coordinated prefabrication services on multiple, distributed computing nodes. In an embodiment, the invention is completely non-intrusive, in which no changes to existing application are required to implement prefabrication of pages.

Abstract: A nucleic acid sequence, including an isolated, purified or recombinant nucleic acid sequence, includes: (a) a nucleic acid sequence encoding a polypeptide encompassed by the present invention, namely, a PLC-zeta; PLC? amino acid sequence, capable of triggering calcium oscillations in oocytes; (b) a sequence substantially homologous to or that hybridizes to sequence (a) under stringent conditions; (c) a sequence substantially homologous to or that hybridizes to the sequences (a) or (b) but for degeneracy of the genetic code; and (d) an oligonucleotide specific for any of the sequences (a), (b) or (c) above.