Abstract: A sensing module for monitoring dosage delivery of a vaporized material, and a portable vaporization unit including the sensing module, include a light sensor that detects disruptions in a light path across a vapor channel, the disruptions caused by the vaporized material flowing through the vapor channel. The light sensor includes a UV light source, which may emit 370 nm wavelength light, and a UV light detector that converts intensity of incident light in the light path into a signal. A microprocessor of the sensing module compares the signal to a baseline measurement to determine the concentration of a medicament in the vapor; then, using the flow rate and activation time of the device, the microprocessor determines the dosage and can perform monitoring and reporting actions based on the dosage. A measuring circuit measures fluctuations in resistance/impedance of a vaporization element to further determine flow rate and/or dosage.

Abstract: This invention describes ways of obtaining nano-particulated adjuvants formed by different synthetic variants of GM3 ganglioside. Depending on the fine structure of the fatty acid in the ceramide of the synthetic GM3, said adjuvants are able to stimulate specifically and in a specialized way the humoral or cellular immune response against accompanying antigens. Particularly, this invention provides immunogenic vaccine compositions that comprise peptides, polypeptides or proteins and the aforementioned nanoparticles, which are formed through the dispersion of hydrophobic proteins of the outer membrane complex (OMC) of Neisseria meningitidis in solutions containing fully synthetic variants of the GM3 ganglioside.

Abstract: In vitro methods for predicting the response of a subject to autologous chimeric antigen receptor T-cell (CAR T-cell) therapy, the methods including determining the methylation status of one or more cytosines in CpG sites of CAR T-cells. Means and kits for carrying out the methods. With the determination of the methylation status of the one or more cytosines in CpG sites, a complete response free of events and long overall survival can be predicted as an outcome of the CAR T-cell therapy, in particular to subjects with B-cell malignancies.

Abstract: Provided herein are methods for aligning raw genetic sequence data generated by a sequencing device. Also provided herein are methods and systems for quantifying the probability that possible alignments for one or more read pairs are correct, for calling known variants, and for detecting novel structural variants.

Abstract: The present disclosure addresses missing procedures on subscription to notification of subscription data changes in current standards and provides for amending the “Policy Data Subscription” data structure to indicate that the URI of the “Policy Data Subscriptions” resource and the URI of the “Individual Policy Data Subscription” resource are excluded from the list of resources for which a modification triggers a notification. The present disclosure also provides for new attributes to be included in the “Policy Data Change Notification” data type.

Abstract: An ergometric treadmill for sport training comprising a screen, a control system and a system configured for collecting, processing, analyzing and visualizing the biomechanical response of a sportsperson while running on the ergometric treadmill; wherein the ergometric treadmill comprises (a) a plurality of MEMS sensors attached by means of supports to the ergometric treadmill connected to a data capture unit; and (b) a data processing unit configured to generate a plurality of parameters related to the physical exercise performed on the ergometric treadmill by a user and synthesize and show, in graphic form, the parameters generated for the user's biofeedback from the treadmill.

Abstract: The present invention relates to a modular shower head assembly, the assembly comprises a water flow regulator module, a swivel adapter and a shower head, a restrictor diffuser has been incorporated into both the water flow regulator module and the swivel adapter module to homogenise the turbulence and deliver a smooth flow, so as to obtain a soft, uniform curtain of rain, in addition, each module is interchangeable in such a way that it can be used according to the user's needs, the assembly is scalable, as the user can purchase each piece separately and couple them together until having a modular shower head assembly, it should be noted that said modules can be used with other shower heads.

Abstract: The present invention is a shower head system that includes various components such as a rotary body, flow regulator, hinged arm, wall mount, and reinforced connector. The system allows for unlimited circular movement of the arm's tubular segments through hinges. Methods for installation and adjustment of resistive force within and outside the hinges are provided to control the relative movement between the tubular segments. To ensure structural strength, a reinforced connector and a plate mount with a seal are incorporated. A specially designed hinge, consisting of two perfectly fitting parts (male and female), is attached to the connector using a small tube. Axial resistive force means are applied to a screw passing through the hinge parts, preventing free-falling of the tubular segments when the hinge is loosened. This system also ensures the safety of the tubular segments by securely trapping them with the screw, eliminating the risk of accidental detachment.

Abstract: An electronic communications method includes sending, by a user device, an electronic communication to a device. The electronic communications method further includes receiving, by the user device, an electronic confirmation message. The electronic communications method further includes sending, by the user device, electronic information. The electronic communications message further includes receiving, by the user device, a value. The value is based on electronically analyzing simultaneous electronic information being sent to the device. The electronic communications message further includes receiving, by the user device, an electronic recommendation message. The electronic recommendation message includes a recommended schedule of communications based on the score. The electronic communications method further includes sending, by the user device, an electronic request message based on the value and the electronic recommendation message.

Abstract: A system, method and non-transitory computer readable media for facilitating network connectivity in a split architecture fronthaul network (102) comprising a plurality of cells (118-1 to 118-5, 120-1 to 120-5) and one or more BBU hubs (108A, 108B), each hub comprising at least a BBU (110-N, 112-M). An example cell allocation process (400B, 500A) is configured to assign cells to the hubs sequentially, i.e., a hub must be completely full (e.g., with respect to certain predetermined capacity such as port utilization) before adding cells to any other hubs. Once a hub is full, the allocated cells are further assigned to the individual BBUs of the hub also sequentially (500B). An optimal cell allocation map (418) is thereby obtained, which may be used in (re)configuring the connectivity between the cells (118-1 to 118-5, 120-1 to 120-5) and the hubs/BBUs (110-N, 112-M).

Abstract: A system and method of resolving a time ambiguity in a receiver based on a received radio signal. The radio signal includes a first signal component and a second signal component. The first and second signal components include code symbols having durations of time The system and method include acquiring each of the signal components, and performing code symbol synchronization and/or code synchronization for each of the codes. The system and method further include estimating a code phase offset between the synchronized codes, or a code-symbol phase offset between the synchronized code symbols. Finally, the system and method include resolving the time ambiguity of the receiver within a time period based on the time-dependent code phase offset or the time-dependent code-symbol phase offset.

Abstract: The invention relates to binary vectors based on compatible and autonomous origins, specifically based on the pBBR1 and RK2 replication origins. These binary vectors are useful for having a wide range of hosts, for their maintenance in Agrobacterium sp. and Escherichia coli, and as a new tool for plant synthetic biology as well as a flexible framework for assembly, transfer and characterization of multiple DNA elements. The binary vectors disclosed are small, preferably less than 3.8 kb in size, stable, include an origin compatible with the most commonly used binary T-DNA vectors, comply with current standards for plant synthetic biology, and allow the administration of multiple T-DNA cassettes by means of the multiplexing of the vectors. The present invention also relates to methods for transferring and expressing nucleic acid sequences using said binary vectors, and to the uses of the same.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for suppressing hotword triggers when detecting a hotword in recorded media are disclosed. In one aspect, a method includes the actions of receiving, by a computing device, audio corresponding to playback of an item of media content. The actions further include determining, by the computing device, that the audio includes an utterance of a predefined hotword and that the audio includes an audio watermark. The actions further include analyzing, by the computing device, the audio watermark. The actions further include based on analyzing the audio watermark, determining, by the computing device, whether to perform speech recognition on a portion of the audio following the predefined hotword.

Abstract: A method includes providing, for each respective audio channel of a plurality of audio channels provided by an operating system of a computing device, a set of successive audio processing stages to apply to the respective audio channel. The method also includes providing, by the operating system, an application programming interface (API) configured to set a plurality of parameters for adjusting the set of successive audio processing stages for each respective audio channel. The method additionally includes receiving, via the API and from an application running on the computing device, one or more values for one or more parameters of the plurality of parameters. The method further includes adjusting, by the operating system, the plurality of audio channels based on the received one or more values for the one or more parameters.

Abstract: A connector seal pack spacer and assembly are employed for use in a fluid line quick connector in an automotive application, for instance. The spacer is located beside an o-ring in installation in the fluid line quick connector. The spacer is designed and constructed with an angled surface that, upon insertion of a spigot in the fluid line quick connector, works to maintain an intended position of the o-ring in the fluid line quick connector. Unwanted mispositioning and dislodging of the o-ring is hence minimized and, in some cases, altogether precluded.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for using audio watermarks with key phrases. One of the methods includes receiving, by a playback device, an audio data stream; determining, before the audio data stream is output by the playback device, whether a portion of the audio data stream encodes a particular key phrase by analyzing the portion using an automated speech recognizer; in response to determining that the portion of the audio data stream encodes the particular key phrase, modifying the audio data stream to include an audio watermark; and providing the modified audio data stream for output.

Abstract: A sensing module for monitoring dosage delivery of a vaporized material, and a portable vaporization unit including the sensing module, include a light sensor that detects disruptions in a light path across a vapor channel, the disruptions caused by the vaporized material flowing through the vapor channel. The light sensor includes a UV light source, which may emit 370 nm wavelength light, and a UV light detector that converts intensity of incident light in the light path into a signal. A microprocessor of the sensing module compares the signal to a baseline measurement to determine the concentration of a medicament in the vapor; then, using the flow rate and activation time of the device, the microprocessor determines the dosage and can perform monitoring and reporting actions based on the dosage. A measuring circuit measures fluctuations in resistance/impedance of a vaporization element to further determine flow rate and/or dosage.

Abstract: A method includes providing, for each respective audio channel of a plurality of audio channels provided by an operating system of a computing device, a set of successive audio processing stages to apply to the respective audio channel. The method also includes providing, by the operating system, an application programming interface (API) configured to set a plurality of parameters for adjusting the set of successive audio processing stages for each respective audio channel. The method additionally includes receiving, via the API and from an application running on the computing device, one or more values for one or more parameters of the plurality of parameters. The method further includes adjusting, by the operating system, the plurality of audio channels based on the received one or more values for the one or more parameters.

Abstract: One embodiment relates to a system that includes a power electronic system and a cooling system. The power electronic system includes a semiconductor switch, which has a rated maximum temperature. The power electronic system itself has a rated maximum power. The system further includes a temperature sensor that is configured to sense a temperature of the (at least one) semiconductor switch. The cooling system is thermally coupled to the power electronic system and configured to carry heat away from the power electronic system using a cooling agent. A system controller is configured to receive information concerning the sensed temperature of the semiconductor switch and a temperature of the cooling agent (coolant). The system controller is further configured to adjust a power of the power electronic system by controlling the switching operation of the semiconductor switch.

Abstract: An electronic communications method includes sending, by a user device, an electronic communication to a device. The electronic communications method further includes receiving, by the user device, an electronic confirmation message. The electronic communications method further includes sending, by the user device, electronic information. The electronic communications message further includes receiving, by the user device, a value. The value is based on electronically analyzing simultaneous electronic information being sent to the device. The electronic communications message further includes receiving, by the user device, an electronic recommendation message. The electronic recommendation message includes a recommended schedule of communications based on the score. The electronic communications method further includes sending, by the user device, an electronic request message based on the value and the electronic recommendation message.