Patents by Inventor Arthur J. Chirino

Arthur J. Chirino has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thrombopoiesis-stimulating proteins having reduced immunogenicity
    Publication number: 20040121953
    Abstract: The present invention relates to variant thrombopoietin proteins that possess thrombopoiesis-stimulating activity and have reduced immunogenicity. In particular, variants of thrombopoietin with reduced ability to bind one or more human class II MHC molecules are described.
    Type: Application
    Filed: August 11, 2003
    Publication date: June 24, 2004
    Inventors: Arthur J. Chirino, Jamal El Yazal, Shannon Alicia Marshall, Peter McDonnell, Jost Vielmetter
  • Protein design automation for designing protein libraries with altered immunogenicity
    Publication number: 20030022285
    Abstract: The present invention relates to the use of a variety of computational methods for modulating the immunogenicity of proteins by identifying and then altering potential amino acid sequences that elicit an immune response in a host organism. In particular, proteins will be screened for MHC binding sequences, T cell epitopes and B cell epitopes.
    Type: Application
    Filed: January 4, 2002
    Publication date: January 30, 2003
    Inventors: Arthur J. Chirino, Bassil I. Dahiyat, John Desjarlais
  • Protein design automation for designing protein libraries with altered immunogenicity
    Publication number: 20020119492
    Abstract: The present invention relates to the use of a variety of computational methods for modulating the immunogenicity of proteins by identifying and then altering potential amino acid sequences that elicit an immune response in a host organism. In particular, proteins will be screened for MHC binding sequences, T cell epitopes and B cell epitopes.
    Type: Application
    Filed: July 10, 2001
    Publication date: August 29, 2002
    Inventors: Arthur J. Chirino, Bassil I. Dahiyat