Patents by Inventor Arturo Perez

Arturo Perez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS
    Publication number: 20090018114
    Abstract: The present application relates to cannabinoid receptor ligands containing compounds of formula (I) wherein A, R1, R2, and R3 are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
    Type: Application
    Filed: July 8, 2008
    Publication date: January 15, 2009
    Applicant: ABBOTT LABORATORIES
    Inventors: William A. Carroll, Michael J. Dart, Arturo Perez-Medrano, Derek W. Nelson
  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS
    Publication number: 20080287510
    Abstract: The present application relates to thiazolylidene containing compounds of formula (I) wherein R1, R2, R3, and R4 are as defined in the specification. The present application also relates to compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
    Type: Application
    Filed: May 15, 2008
    Publication date: November 20, 2008
    Applicant: Abbott Laboratories
    Inventors: William A. Carroll, Michael J. Dart, Arturo Perez-Medrano, Jennifer M. Frost, Sridhar Peddi
  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS
    Publication number: 20080242654
    Abstract: The present application relates to thiazolylidene containing compounds of formula (I) wherein R1, R2, R3, R4, L2 and A are as defined in the specification. Compositions comprising such compounds, and methods for treating conditions and disorders using such compounds and compositions are also disclosed.
    Type: Application
    Filed: March 19, 2008
    Publication date: October 2, 2008
    Applicant: ABBOTT LABORATORIES
    Inventors: Teodozyj Kolasa, Jennifer M. Frost, Meena V. Patel, Steven P. Latshaw, Arturo Perez-Medrano, Xueqing Wang, Sridhar Peddi, William A. Carroll, Michael J. Dart
  • Amino-Tetrazoles Analogues and Methods of Use
    Publication number: 20080171733
    Abstract: A compound having Formula (I) or Formula (II) is disclosed as an P2X7 antagonist, wherein A, B, C, Y, Y, Z, m, v, R1, R2, R3, R4, and R5, are as defined in the description. Methods and compositions for treating disease or condition modulated by P2X7 are also disclosed.
    Type: Application
    Filed: March 19, 2008
    Publication date: July 17, 2008
    Applicant: ABBOTT LABORATORIES
    Inventors: William A. Carroll, Arturo Perez-Medrano, Alan S. Florjancic, Derek W. Nelson, Sridhar Peddi, Tongmei Li, Eric M. Bunnelle, Gavin Hirst, Biqin C. Li
  • Piperazines as P2X7 antagonists
    Publication number: 20080076924
    Abstract: Novel compounds of Formula (I) or pharmaceutically acceptable salts thereof, metabolites thereof, isomers thereof, enantiomers thereof or prodrugs thereof of Formula (I) wherein the substituents are as defined herein, which are useful as therapeutic agents.
    Type: Application
    Filed: June 29, 2007
    Publication date: March 27, 2008
    Inventors: Patrick Betschmann, William Carroll, Anna Ericsson, Shannon Fix-Stenzel, Michael Friedman, Gavin Hirst, Nathan Josephsohn, Biqin Li, Arturo Perez-Medrano, Michael Morytko, Paul Rafferty, Haipeng Chen
  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF
    Publication number: 20080064699
    Abstract: The present invention relates to compounds of formula (I), or pharmaceutically acceptable salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1, R2, R3, R4, and L2, are defined in the specification, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
    Type: Application
    Filed: May 31, 2007
    Publication date: March 13, 2008
    Inventors: Alan Florjancic, Michael Dart, Keith Ryther, Arturo Perez-Medrano, William Carroll, Meena Patel, Karin Tietje, Tongmei Li, Teodozyj Kolasa, Megan Gallagher, Sridhar Peddi, Jennifer Frost, Derek Nelson
  • NOVEL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF
    Publication number: 20080058335
    Abstract: The present invention relates to compounds of formula (I), or pharmaceutical salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1, R2, R3, and L1 are defined in the specfication, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions. The present invention also relates to compounds of formula (II), or pharmaceutical salts, prodrugs, salts of prodrugs, or combinations thereof, wherein R1a, R2a and (Rx)n are as defined in the specification, compositions comprising such compounds, and methods of treating conditions and disorders using such compounds and compositions.
    Type: Application
    Filed: May 30, 2007
    Publication date: March 6, 2008
    Inventors: Alan Florjancic, Michael Dart, Keith Ryther, Arturo Perez-Medrano, William Carroll, Meena Patel, Karin Tietje, Tongmei Li, Teodozyj Kolasa, Megan Gallagher, Sridhar Peddi, Jennifer Frost, Derek Nelson
  • P2X7, receptor antagonists and uses thereof
    Publication number: 20070259920
    Abstract: A compound having formula (I) wherein R1, R2, R3, R4, R5 and R6 are defined in the description, is disclosed as an P2X7 antagonist. Methods and compositions for treating disease or condition modulated by P2X7 are also disclosed.
    Type: Application
    Filed: November 7, 2006
    Publication date: November 8, 2007
    Inventors: William Carroll, Arturo Perez-Medrano, Tongmei Li
  • Cyanoamidine P2X7 Antagonists for the Treatment of Pain
    Publication number: 20070232686
    Abstract: Novel cyanoamidines compounds of formula (I) and (II) and their derivatives wherein R1-R12 are as defined in the specification act as antagonists of the P2X7 receptor. These compounds are particularly useful in the treatment of pain, inflammation and neurodegeneration states.
    Type: Application
    Filed: May 18, 2007
    Publication date: October 4, 2007
    Inventors: William Carroll, Arturo Perez-Medrano, Sridhar Peddi, Alan Florjancic
  • Cyanoamidine P2Xantagonists for the treatment of pain
    Patent number: 7241776
    Abstract: Novel cyanoamidines compounds of formula (I) and (II) and their derivatives wherein R1-R12 are as defined in the specification act as antagonists of the P2X7 receptor. These compounds are particularly useful in the treatment of pain, inflammation and neurodegeneration states.
    Type: Grant
    Filed: August 2, 2004
    Date of Patent: July 10, 2007
    Assignee: Abbott Laboratories
    Inventors: William A. Carroll, Arturo Perez-Medrano, Sridhar Peddi, Alan S. Florjancic
  • P2X7 receptor antagonists and methods of use
    Publication number: 20070105842
    Abstract: The invention is directed to compounds that are P2X7 antagonist and have the formula (I) or (II) or a pharmaceutically acceptable salt, prodrug, salt of a prodrug or a combination thereof, wherein R1, R2, and R3 are defined in the specification. The invention is also directed to a method of selectively inhibiting P2X7 activity comprising administering to a patient in need of such treatment a therapeutically effective amount of a compound of formula (III), (IV) or (V) wherein R6, R7, R8, R9, R10, and R11 are defined in the specification.
    Type: Application
    Filed: November 6, 2006
    Publication date: May 10, 2007
    Inventors: William Carroll, Alan Florjancic, Arturo Perez-Medrano, Sridhar Peddi
  • Amino-tetrazoles analogues and methods of use
    Publication number: 20070049584
    Abstract: A compound having Formula (I) or Formula (II) is disclosed as an P2X7 antagonist, wherein A, B, C, Y, Y, Z, m, v, R1, R2, R3, R4, and R5, are as defined in the description. Methods and compositions for treating disease or condition modulated by P2X7 are also disclosed.
    Type: Application
    Filed: April 29, 2005
    Publication date: March 1, 2007
    Inventors: William Carroll, Arturo Perez-Medrano, Alan Florjancic, Derek Nelson, Sridhar Peddi, Tongmei Li, Eric Bunnelle, Gavin Hirst, Biquin Li
  • Use of selective P2X7 receptor antagonists
    Publication number: 20060211739
    Abstract: The present invention relates to the use of selective P2X7 receptor antagonists of formula I, or a pharmaceutically acceptable salt or prodrug thereof wherein D, R1 and R2 are as defined in claim 1, for the treatment of neuropathic pain, chronic inflammatory pain, inflammation, neurodegeneration and for promoting neuroregeneration,
    Type: Application
    Filed: February 1, 2006
    Publication date: September 21, 2006
    Inventors: Arturo Perez-Medrano, Derek Nelson, William Carroll, Michael Kort, Robert Gregg, Eric Voight, Michael Jarvis, Elizabeth Kowaluk
  • Amino-tetrazole analogues and methods of use
    Publication number: 20060052374
    Abstract: A compound having Formula (I) or Formula (II) is disclosed as an P2X7 antagonist, wherein A, B, C, Y, Y, Z, m, v, R1, R2, R3, R4, and R5, are as defined in the description. Methods and compositions for treating disease or condition modulated by P2X7 are also disclosed.
    Type: Application
    Filed: September 7, 2005
    Publication date: March 9, 2006
    Inventors: William Carroll, Arturo Perez-Medrano, Alan Florjancic, Derek Nelson, Sridhar Peddi, Tongmei Li, Eric Bunnelle, Gavin Hirst, Biquin Li
  • Cyanoamidine P2X7 antagonists for the treatment of pain
    Publication number: 20060025614
    Abstract: Novel cyanoamidines compounds of formula (I) and (II) and their derivatives wherein R1-R12 are as defined in the specification act as antagonists of the P2X7 receptor. These compounds are particularly useful in the treatment of pain, inflammation and neurodegeneration states.
    Type: Application
    Filed: August 2, 2004
    Publication date: February 2, 2006
    Inventors: William Carroll, Arturo Perez-Medrano, Sridhar Peddi, Alan Florjancic
  • Web-based customized information retrieval and delivery method and system
    Publication number: 20040230566
    Abstract: A web-based multi-user system and method for identifying, retrieving, and delivering information corresponding to items contained in a user search list from two or more information sources on the World Wide Web (WWW) is provided. The system includes a central server that periodically searches the information sources on the WWW for information corresponding to the items contained in the user search list. The central server retrieves the information onto a storage database where a determination is made as to whether the information is current. The central server electronically delivers only the current information to the user. The system and method therefore provides to the user automatic and periodic electronic reports containing only current or updated information corresponding to items contained in the user search list that the user desires to track.
    Type: Application
    Filed: September 17, 2003
    Publication date: November 18, 2004
    Inventors: Srinivas Balijepalli, Joshua M. Kopelman, Arturo Perez, Michael A. Puscar, Shuchun Zhang
  • Potassium channel openers
    Patent number: 6645968
    Abstract: Compounds of formula I: are useful in treating diseases prevented by or ameliorated with potassium channel openers. Also disclosed are potassium channel opening compositions and a method of opening potassium channels in a mammal.
    Type: Grant
    Filed: February 5, 2001
    Date of Patent: November 11, 2003
    Assignee: Abbott Laboratories
    Inventors: Robert J. Altenbach, Hao Bai, Jorge D. Brioni, William A. Carroll, Murali Gopalakrishnan, Robert J. Gregg, Mark W. Holladay, Peggy P. Huang, John F. Kincaid, Michael E. Kort, Philip R. Kym, John K. Lynch, Arturo Perez-Medrano, Henry Q. Zhang
  • Aminal diones as potassium channel openers
    Patent number: 6495576
    Abstract: Compounds of formula (I) may be useful in treating diseases prevented by or ameliorated with potassium channel openers.
    Type: Grant
    Filed: January 14, 2002
    Date of Patent: December 17, 2002
    Assignee: Abbott Laboratories
    Inventors: Michael E. Kort, Robert J. Gregg, William A. Carroll, Arturo Perez Medrano, Jürgen Dinges, Fatima Z. Basha
  • Aminal diones as potassium channel openers
    Publication number: 20020165264
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: January 14, 2002
    Publication date: November 7, 2002
    Inventors: Michael E. Kort, Robert J. Gregg, William A. Carroll, Arturo Perez Medrano, Jurgen Dinges, Fatima Z. Basha
  • Aminal Diones as potassium channel openers
    Publication number: 20020147230
    Abstract: Compounds of formula (I) 1
    Type: Application
    Filed: February 7, 2001
    Publication date: October 10, 2002
    Inventors: Michael E. Kort, Robert J. Gregg, William A. Carroll, Arturo Perez Medrano, Jurgen Dinges