Abstract: An object of the present invention is to provide an oligonucleotide useful as a therapeutic agent for dyslipidemia that has excellent binding affinity to the PCSK9 gene as well as stability and safety. The oligonucleotide of the present invention contains a sugar-modified nucleoside, the sugar-modified nucleoside has a bridging structure between 4?-position and 2?-position, and the oligonucleotide can bind to the human PCSK9 gene. Also, the present invention provides a therapeutic agent for dyslipidemia containing the oligonucleotide as an active ingredient, and the therapeutic agent preferably contains a bioabsorbable material as a carrier. The bioabsorbable material is preferably atelocollagen or peptide gel.

Abstract: A method is provided for thinning a wafer, for example a wafer containing Through Silicon Vias (TSV). The method includes providing a bonding wafer coupled to a handling wafer, and performing a wafer edge trimming process that forms a trimmed bonding wafer, where the wafer edge trimming process removes an edge portion of the bonding wafer and exposes an upper surface of the handling wafer. The method further includes forming a protective mask on the trimmed bonding wafer and on the exposed upper surface of the handling wafer, planarizing the protective mask and the trimmed bonding wafer, and selectively removing the planarized protective mask by an etching process. In one embodiment, the removing includes performing a first wet etching process that selectively removes a portion of the planarized trimmed bonding wafer relative to the planarized protective mask, and performing a second wet etching process that selectively removes the planarized protective mask.

Abstract: An LED module comprises: an insulating substrate in plate form; first main and sub terminals for connection to an external circuit formed near the first side of the insulating substrate; second main and sub terminals for connection to an external circuit formed near the second side opposite to the first side; three or more connecting wires formed on the insulating substrate for connecting LEDs continuously aligned at a distance from each other in series; LEDs individually connected between the connecting wires adjacent to each other and connected in series in a same direction; and a first passing wire formed on the insulating substrate for electrically connecting the first sub-terminal to the second sub-terminal, wherein a first connecting wire located on one side is electrically connected to the first main terminal, and a second connecting wire located on the other side is electrically connected to the second main terminal.

Abstract: A zoom lens includes: a first lens group with a positive refractive power, including a reflection optical element; a second lens group with a negative refractive power; a third lens group with a positive refractive power; a fourth lens group with a positive refractive power; and a fifth lens group with a negative refractive power. A power of the zoom lens varies by moving the second lens group, the fourth lens group, and the fifth lens group along an optical axis. A negative lens in the first lens group or a positive lens in the second lens group satisfies the predetermined conditions relating to a refractive index and an Abbe number.

Abstract: Provided is a zoom lens including a first lens group having negative refractive power, a second lens group having positive refractive power, a third lens group having negative refractive power, and a fourth lens group having positive refractive power. The first lens group contains a reflective optical element that bends the light path. In order from the object side, the second lens group comprises a positive 2p1 lens, a negative 2n lens, and a positive 2p2 lens. The third lens group comprises a single negative lens. Letting n2n be the index of refraction of the 2n lens, n2p2 be the index of refraction of the 2p2 lens, ?2p2 be the Abbe number of the 2p2 lens, and ?2n be the Abbe number of the 2n lens, 0.30<n2n?n2p2<0.50 and 30<?2p2??2n<60.

Abstract: A user interface device allocates each of functions for operating an instrument to fingertips in response to a hand movement and allowing an operator to intuitively comprehend the allocation of each of the functions to the fingertips. The device includes a GUI button allocation section that first allocates a GUI button, read out from a GUI button data storing section, to each fingertip in a hand shape acquired by a hand shape acquiring section when a contact position acquiring section detects a contact to an operation surface by the operator. Then, in accordance with a change of hand shape direction, the GUI button allocation section reallocates the GUI button to each fingertip of the hand shape.

Abstract: An input device for a mobile body allows for a safe input operation at the time of operating equipment, such as a car, regardless of whether the mobile body is traveling or stopped. The input device includes an input section for receiving inputs by hand and voice operations, a traveling state determination section for determining a traveling state of the mobile body, and an item executability determination section for determining, in the determined traveling state, whether each of the received inputs corresponds to an item executable by the hand and voice operations. The input device also includes a display content generation section for generating a display mode which distinguishably shows whether nor not the item is executable by the hand and voice operations in accordance with a determination by the item executability determination section, and a display section for displaying the generated display mode.

Abstract: A voice input device, in which a content spoken by a user is reflected on a confirmation screen when executing the content, allows the user to confirm that a command, corresponding to the content which is spoken by the user who intended for the execution, is executed after being recognized by the voice input device.

Abstract: An LED substrate comprises holes having an elliptical shape through which fixing screws are inserted. The fixing screw has a head portion, an unthreaded neck portion whose diameter smaller than that of the head portion, and a threaded shaft portion whose diameter smaller than that of the neck portion. A major axis of the hole is larger than the diameter of the head portion, and a minor axis thereof is smaller than the diameter of the head portion and larger than the diameter of the neck portion. The LED substrate further comprises counterbored recesses to which anchoring claws provided in a cabinet are fitted. A width of the counterbored recess in a direction of the major axis of the hole is larger than that of the anchoring claw. The counterbored recesses are formed on both of two sides of the LED substrate facing each other in a first direction.

Abstract: An image operating device which is inexpensive and capable of allowing a user to understand to what extent an image operation of movement, enlargement and reduction, rotation or the like is performed on an image.

Abstract: An input device for inputting a command and information to a device, includes a body shape input section acquiring body shape information of a user and a display information generation section generating a display image necessary for the user to input the command and the information. Further, the input device includes an operation section having an operation surface corresponding to the display image, a body shape extraction section extracting a portion corresponding to the operation surface from the body shape information acquired by the body shape input section and generating a body image, an image composition section making a composite image of the display image generated by the display information generation section and the body image generated by the body shape extraction section, and a display section displaying the composite image made by the image composition section.

Abstract: Object: To provide a small-sized, durable metal mold structure capable of casting two cylinder blocks at a time. Solution: A metal mold structure for casting two cylinder blocks W at a time, comprises left and right inner slide cores 5a, 5b being interposed between two cylinder blocks W, hydraulic cylinder units 10, 11 adapted to move each of these left and right inner slide cores 5a, 5b, inclined holes 12, 13 being provided in each of the left and right inner slide cores 5a, 5b, and inclined pins 14, 15 being provided on a fixed mold 2 and inserted into the inclined holes 12, 13 with a predetermined clearance C1, C2 maintained respectively, wherein, when the fixed mold 2 is operated, each of the inclined pins 14, 15 pushes a wall surface of the inclined hole 12, 13 in such a way as to move the left and right inner slide cores 5a, 5b in a mold opening direction respectively. Preferably, the clearances C1, C2 are different with respect to the left and right inner slide cores 5a, 5b.

Abstract: A light emitting module board which is compatible with a plurality of screen sizes and is used for a backlight apparatus of a liquid crystal display panel is provided. A light emitting module includes a first connector 15 and a second connector 16, each including a plurality of cathode terminals and at least one anode terminal, at each end of the board, and can be connected to another one to each other through the connectors in multi-level. A cathode wiring 14 for supplying a cathode control signal includes first cathode wirings which connect the cathode terminals of the first connector and light emitting bodies to supply a control signal to the light emitting bodies in the light emitting module, and second cathode wirings which connect the cathode terminals of the first and second connectors to supply a control signal to the light emitting bodies on a downstream light emitting module.

Abstract: Object: To provide a small-sized, durable metal mold structure capable of casting two cylinder blocks at a time. Solution: A metal mold structure for casting two cylinder blocks W at a time, comprises left and right inner slide cores 5a, 5b being interposed between two cylinder blocks W, hydraulic cylinder units 10, 11 adapted to move each of these left and right inner slide cores 5a, 5b, inclined holes 12, 13 being provided in each of the left and right inner slide cores 5a, 5b, and inclined pins 14, 15 being provided on a fixed mold 2 and inserted into the inclined holes 12, 13 with a predetermined clearance C1, C2 maintained respectively, wherein, when the fixed mold 2 is operated, each of the inclined pins 14, 15 pushes a wall surface of the inclined hole 12, 13 in such a way as to move the left and right inner slide cores 5a, 5b in a mold opening direction respectively. Preferably, the clearances C1, C2 are different with respect to the left and right inner slide cores 5a, 5b.

Abstract: Character information recognition means extracts, through a character recognition process, character information from a selection button included in an index image. Based on text data having been outputted from the character information recognition means, index dictionary creation means creates an index dictionary usable for a speech recognition process performed by speech recognition means. The speech recognition means performs the speech recognition process by using speech data retrieved through an ADC and the index dictionary stored in storage means. Based on a result of the speech recognition process performed by the speech recognition means, reproduction control means performs reproduction control of a chapter. Thus, a desired button can be selected by speech, from chapter selection buttons displayed on a chapter selection image of a DVD video.

Abstract: An in-vehicle recording/reproduction device (121) records in a recording device a program which the user starts watching, and reads and reproduces the data when watching is permitted, such as, for example, when a vehicle is stopped. The in-vehicle recording/reproduction device (121) transmits recording information about recording, such as a program, a time, and the like, to an in-home recording/reproduction device (303). The in-home recording/reproduction device (303) records the same program as that recorded by the in-vehicle recording/reproduction device (121) based on the recording information. The in-vehicle recording/reproduction device (121) transmits to the in-home recording/reproduction device (303) reproduction information indicating which scene was last reproduced in the in-vehicle recording/reproduction device (121). The in-home recording/reproduction device (303) performs reproduction based on the reproduction information.

Abstract: A zoom lens includes, in order from an object side thereof: a first lens group with a positive refractive power; a second lens group with a negative refractive power; a third lens group with a positive refractive power; a fourth lens group with a negative refractive power; and a fifth lens group with a positive refractive power. A power of the zoom lens is varied by changing intervals between neighboring lens groups in the first through fifth lens groups. The second lens group includes a cemented lens consisting of one positive lens and one negative lens, and the third lens group includes a cemented lens consisting of two positive lenses and one negative lens.

Abstract: A method is provided for thinning a wafer, for example a wafer containing Through Silicon Vias (TSV). The method includes providing a bonding wafer coupled to a handling wafer, and performing a wafer edge trimming process that forms a trimmed bonding wafer, where the wafer edge trimming process removes an edge portion of the bonding wafer and exposes an upper surface of the handling wafer. The method further includes forming a protective mask on the trimmed bonding wafer and on the exposed upper surface of the handling wafer, planarizing the protective mask and the trimmed bonding wafer, and selectively removing the planarized protective mask by an etching process. In one embodiment, the removing includes performing a first wet etching process that selectively removes a portion of the planarized trimmed bonding wafer relative to the planarized protective mask, and performing a second wet etching process that selectively removes the planarized protective mask.

Abstract: A user interface system having an improved usability is provided.

Abstract: An LED substrate comprises holes having an elliptical shape through which fixing screws are inserted. The fixing screw has a head portion, an unthreaded neck portion whose diameter smaller than that of the head portion, and a threaded shaft portion whose diameter smaller than that of the neck portion. A major axis of the hole is larger than the diameter of the head portion, and a minor axis thereof is smaller than the diameter of the head portion and larger than the diameter of the neck portion. The LED substrate further comprises counterbored recesses to which anchoring claws provided in a cabinet are fitted. A width of the counterbored recess in a direction of the major axis of the hole is larger than that of the anchoring claw. The counterbored recesses are formed on both of two sides of the LED substrate facing each other in a first direction.