Patents by Inventor Bahram Asgharian

Bahram Asgharian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PUNCTAL PLUG COMPRISING A WATER-INSOLUBLE POLYMERIC MATRIX
    Publication number: 20080114076
    Abstract: Disclosed is a pharmaceutical composition comprising a water insoluble polymer matrix that comprises a bioerodable polyester polymer or a fatty acid based polyester polymer, or a mixture of both polymers, wherein the polymer matrix has a melting point of less than 60° C., and wherein the composition is liquid or paste at room temperature and is formulated to occlude a punctual channel in a subject and conforms to the shape of the canalicular or punctal channel.
    Type: Application
    Filed: November 8, 2007
    Publication date: May 15, 2008
    Applicant: Alcon Manufacturing Ltd.
    Inventors: Bahram Asgharian, Masood A. Chowhan
  • WATER INSOLUBLE POLYMER MATRIX FOR DRUG DELIVERY
    Publication number: 20080113027
    Abstract: Disclosed is a pharmaceutical composition comprising (a) a bioerodible water insoluble polymer matrix comprising a polyester polymer, wherein the polymer matrix has a melting point of less than 60° C. and (b) an active agent dispersed within the polymer matrix, wherein the composition is formulated to controllably release the active agent for a pre-determined period of time to a target site. Also disclosed are methods of treating a disease or condition with the disclosed compositions.
    Type: Application
    Filed: November 8, 2007
    Publication date: May 15, 2008
    Applicant: Alcon Manufacturing Ltd.
    Inventors: Bahram Asgharian, Masood A. Chowhan, Martin B. Wax
  • OPHTHALMIC COMPOSITIONS CONTAINING GALACTOMANNAN POLYMERS AND BORATE
    Publication number: 20070098677
    Abstract: The present invention is directed to ophthalmic compositions containing a gelling amount of a combination of galactomannan polysaccharides and borates. The compositions gel or partially gel upon administration to the eye. The present invention also discloses methods of topical ophthalmic administration of the compositions to the eye.
    Type: Application
    Filed: December 19, 2006
    Publication date: May 3, 2007
    Inventor: Bahram Asgharian
  • Ophthalmic compositions containing a PVA/borate gelling system
    Publication number: 20070059274
    Abstract: Ophthalmic compositions containing a polyvinyl alcohol/borate gelling system are described. The system forms a gel or partial gel when the composition is applied to the eye. The compositions are particularly useful as ocular lubricants or artificial tears.
    Type: Application
    Filed: November 17, 2006
    Publication date: March 15, 2007
    Inventors: Bahram Asgharian, David Meadows
  • Ophthalmic compositions containing galactomannan polymers and borate
    Patent number: 7169767
    Abstract: The present invention is directed to ophthalmic compositions containing a gelling amount of a combination of galactomannan polysaccharides and borates. The compositions gel or partially gel upon administration to the eye. The present invention also discloses methods of topical ophthalmic administration of the compositions to the eye.
    Type: Grant
    Filed: November 24, 2004
    Date of Patent: January 30, 2007
    Assignee: Alcon Manufacturing, Ltd.
    Inventor: Bahram Asgharian
  • Use of low molecular weight amino alcohols in ophthalmic compositions
    Publication number: 20060264516
    Abstract: The use of low molecular weight amino alcohols in ophthalmic compositions is described. These compounds have been found to enhance the efficacy of anti-microbial preservatives.
    Type: Application
    Filed: January 30, 2006
    Publication date: November 23, 2006
    Inventor: Bahram Asgharian
  • Use of low molecular weight amino alcohols in ophthalmic compositions
    Patent number: 7045095
    Abstract: The use of low molecular weight amino alcohols in ophthalmic compositions is described. These compounds have been found to enhance the efficacy of anti-microbial preservatives.
    Type: Grant
    Filed: June 28, 2005
    Date of Patent: May 16, 2006
    Assignee: Alcon Manufacturing, Ltd.
    Inventor: Bahram Asgharian
  • Use of low molecular weight amino alcohols in ophthalmic compositions
    Publication number: 20050239900
    Abstract: The use of low molecular weight amino alcohols in ophthalmic compositions is described. These compounds have been found to enhance the efficacy of anti-microbial preservatives.
    Type: Application
    Filed: June 28, 2005
    Publication date: October 27, 2005
    Inventor: Bahram Asgharian
  • Use of low molecular weight amino alcohols in ophthalmic compositions
    Patent number: 6949218
    Abstract: The use of low molecular weight amino alcohols in ophthalmic compositions is described. These compounds have been found to enhance the efficacy of anti-microbial preservatives.
    Type: Grant
    Filed: October 22, 2001
    Date of Patent: September 27, 2005
    Assignee: Alcon Manufacturing, Ltd.
    Inventor: Bahram Asgharian
  • Use of cooling agents to relieve mild ocular irritation and enhance comfort
    Publication number: 20050137166
    Abstract: Ophthalmic compositions containing very low concentrations (e.g., 1 to 50 ppm) of cooling agents are described. The cooling agents are less volatile and less prone to causing ocular discomfort than agents previously utilized to obtain an ocular cooling effect, such as menthol. The cooling agents are preferably contained in a vehicle that forms a gel or partial gel upon application to the eye.
    Type: Application
    Filed: December 1, 2004
    Publication date: June 23, 2005
    Inventors: Bahram Asgharian, David Meadows
  • Ophthalmic compositions containing a polysaccharide/borate gelling system
    Publication number: 20050129771
    Abstract: Topical ophthalmic compositions that form a gel or partial gel upon application to the eye are described. The compositions are particularly useful as artificial tears and ocular lubricants, but may also be utilized for the topical delivery of pharmaceutically active compounds to the eye. The compositions contain a polysaccharide/borate gelling system. The polysaccharides that may be utilized contain cis-diol groups and have a structure that is predominately linear, with a slight degree of branching.
    Type: Application
    Filed: December 1, 2004
    Publication date: June 16, 2005
    Inventor: Bahram Asgharian
  • Ophthalmic compositions containing a PVA/borate gelling system
    Publication number: 20050129770
    Abstract: Ophthalmic compositions containing a polyvinyl alcohol/borate gelling system are described. The system forms a gel or partial gel when the composition is applied to the eye. The compositions are particularly useful as ocular lubricants or artificial tears.
    Type: Application
    Filed: December 1, 2004
    Publication date: June 16, 2005
    Inventors: Bahram Asgharian, David Meadows
  • Ophthalmic compositions containing galactomannan polymers and borate
    Publication number: 20050075313
    Abstract: The present invention is directed to ophthalmic compositions containing a gelling amount of a combination of galactomannan polysaccharides and borates. The compositions gel or partially gel upon administration to the eye. The present invention also discloses methods of topical ophthalmic administration of the compositions to the eye.
    Type: Application
    Filed: November 24, 2004
    Publication date: April 7, 2005
    Inventor: Bahram Asgharian
  • Ophthalmic compositions containing galactomannan polymers and borate
    Patent number: 6838449
    Abstract: The present invention is directed to ophthalmic compositions containing a gelling amount of a combination of galactomannan polysaccharides and borates. The compositions gel or partially gel upon administration to the eye. The present invention also discloses methods of topical ophthalmic administration of the compositions to the eye.
    Type: Grant
    Filed: May 14, 2003
    Date of Patent: January 4, 2005
    Assignee: Alcon Manufacturing, Ltd.
    Inventor: Bahram Asgharian
  • Ophthalmic compositions containing galactomannan polymers and borate
    Publication number: 20030206970
    Abstract: The present invention is directed to ophthalmic compositions containing a gelling amount of a combination of galactomannan polysaccharides and borates. The compositions gel or partially gel upon administration to the eye. The present invention also discloses methods of topical ophthalmic administration of the compositions to the eye.
    Type: Application
    Filed: May 14, 2003
    Publication date: November 6, 2003
    Inventor: Bahram Asgharian
  • Ophthalmic compositions containing galactomannan polymers and borate
    Patent number: 6583124
    Abstract: The present invention is directed to ophthalmic compositions containing a gelling amount of a combination of galactomannan polysaccharides and borates. The compositions gel or partially gel upon administration to the eye. The present invention also discloses methods of topical ophthalmic administration of the compositions to the eye.
    Type: Grant
    Filed: April 22, 2002
    Date of Patent: June 24, 2003
    Assignee: Alcon Manufacturing, Ltd.
    Inventor: Bahram Asgharian
  • Methods of performing surgery with galactomannan polymers and borate
    Patent number: 6495608
    Abstract: The present invention is directed to viscoelastic systems comprising a combination of a galactomannan polysaccharide containing composition and borate containing composition. The two compositions gel or partially gel upon combination. The present invention also discloses methods of using the systems during surgery and, in particular, eye surgery.
    Type: Grant
    Filed: January 26, 2000
    Date of Patent: December 17, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventor: Bahram Asgharian
  • Ophthalmic compositions containing galactomannan polymers and borate
    Publication number: 20020183280
    Abstract: The present invention is directed to ophthalmic compositions containing a gelling amount of a combination of galactomannan polysaccharides and borates. The compositions gel or partially gel upon administration to the eye. The present invention also discloses methods of topical ophthalmic administration of the compositions to the eye.
    Type: Application
    Filed: April 22, 2002
    Publication date: December 5, 2002
    Inventor: Bahram Asgharian
  • Solutions for treating contact lenses
    Patent number: 6486215
    Abstract: Contact lens care compositions for the treatment of hard contact lenses are disclosed. The compositions are useful for rinsing, cleaning, disinfecting and storing of hard contact lenses. The compositions contain an unique gelling system involving galactomannan polysaccharides and borates to allow for the conditioning of the lens when it is reinserted in the eye of the user. Methods of using these compositions are also disclosed.
    Type: Grant
    Filed: June 18, 2001
    Date of Patent: November 26, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventor: Bahram Asgharian
  • Ophthalmic compositions containing galactomannan polymers and borate
    Patent number: 6486138
    Abstract: The present invention is directed to ophthalmic compositions containing a gelling amount of a combination of galactomannan polysaccharides and borates. The compositions gel or partially gel upon administration to the eye. The present invention also discloses methods of topical ophthalmic administration of the compositions to the eye.
    Type: Grant
    Filed: November 23, 1999
    Date of Patent: November 26, 2002
    Assignee: Alcon Manufacturing, Ltd.
    Inventors: Bahram Asgharian, Gerald Cagle, Mandar V. Shah, Kerry L. Markwardt