Patents by Inventor Bastiaan Nuijen

Bastiaan Nuijen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Medical Compositions for Intravesical Treatment of Bladder Cancer
    Publication number: 20080166402
    Abstract: Methods for treating bladder cancer comprising intravesicular administration of a stabilized pharmaceutical formulation comprising 5-(1-aziridinyl)-3-(hydroxymethyl)-2-[(E)-3-hydroxyprop-1-enyl]-1-methyl-1H-indole-4,7-dione (EO9). More specifically, the stabilized pharmaceutical formulation is instilled in the bladder for a time sufficient to treat the cancer.
    Type: Application
    Filed: March 21, 2008
    Publication date: July 10, 2008
    Applicant: Spectrum Pharmaceuticals, Inc.
    Inventors: Bastiaan Nuijen, Ernie Pfadenhauer, Jos H. Beijnen
  • Medical Compositions for Intravesical Treatment of Bladder Cancer
    Publication number: 20070010570
    Abstract: Anti-cancer coating compositions comprising 3-hydroxymethyl-5-aziridinyl-1-1-methyl-2-[1H-indole-4,7-dione]propenol (E09) are disclosed. More specifically, the coating compositions comprise EO9 and a formulation vehicle. The formulation vehicle improves the solubility and stability of EO9. Additionally, the coating compositions can include coating agents that provide better adhesion of the coating composition to the bladder wall during intravesical delivery of the coating composition.
    Type: Application
    Filed: September 13, 2006
    Publication date: January 11, 2007
    Applicant: SPECTRUM PHARMACEUTICALS, INC.
    Inventors: Bastiaan Nuijen, Ernie Pfadenhauer, Jos Beijnen
  • Formulations
    Publication number: 20060094687
    Abstract: Ecteinascidin formulations, methods of preparing the same, articles of manufacture and kits with such formulations, and methods of treating proliferative diseases with the same formulations are provided.
    Type: Application
    Filed: October 28, 2005
    Publication date: May 4, 2006
    Inventors: Jacob Beijnen, Bastiaan Nuijen, Pilar Salve, Maria Barreira
  • Medical compositions for intravesical treatment of bladder cancer
    Publication number: 20050215615
    Abstract: Anti-cancer coating compositions comprising 3-hydroxymethyl-5-aziridinyl-1-1-methyl-2-[1 H-indole-4,7-dione]propenol (E09) are disclosed. More specifically, the coating compositions comprise EO9 and a formulation vehicle. The formulation vehicle improves the solubility and stability of EO9. Additionally, the coating compositions can include coating agents that provide better adhesion of the coating composition to the bladder wall during intravesical delivery of the coating composition.
    Type: Application
    Filed: April 1, 2005
    Publication date: September 29, 2005
    Applicant: Spectrum Pharmaceuticals, Inc.
    Inventors: Bastiaan Nuijen, Ernie Pfadenhauer, Jos Beijnen
  • Medical compositions for intravesical treatment of bladder cancer
    Patent number: 6894071
    Abstract: Anti-cancer coating compositions comprising 3-hydroxymethyl-5-aziridinyl-1-1-methyl-2-[1H-indole-4,7-dione]propenol (E09) are disclosed. More specifically, the coating compositions comprise EO9 and a formulation vehicle. The formulation vehicle improves the solubility and stability of EO9. Additionally, the coating compositions can include coating agents that provide better adhesion of the coating composition to the bladder wall during intravesical delivery of the coating composition.
    Type: Grant
    Filed: November 1, 2002
    Date of Patent: May 17, 2005
    Assignee: Spectrum Pharmaceuticals, Inc.
    Inventors: Bastiaan Nuijen, Ernie Pfadenhauer, Jos H. Beijnen
  • Medical compositions for intravesical treatment of bladder cancer
    Publication number: 20030133954
    Abstract: Anti-cancer coating compositions comprising 3-hydroxymethyl-5-aziridinyl-1-1-methyl-2-[1H-indole-4,7-dione]propenol (E09) are disclosed. More specifically, the coating compositions comprise EO9 and a formulation vehicle. The formulation vehicle improves the solubility and stability of EO9. Additionally, the coating compositions can include coating agents that provide better adhesion of the coating composition to the bladder wall during intravesical delivery of the coating composition.
    Type: Application
    Filed: November 1, 2002
    Publication date: July 17, 2003
    Inventors: Bastiaan Nuijen, Ernie Pfadenhauer, Jos H. Beijnen