Abstract: This invention relates to compounds that are agonists of the muscarinic M1 and/or M4 receptor and which are useful in the treatment of diseases mediated by the muscarinic M1 and M4 receptors. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formula where X1; X2; R1 and R4 are as defined herein.

Abstract: An attenuation or “gap” may be inserted into at least a first frequency range of at least first and second audio playback signals of a content stream during at least a first time interval to generate at least first and second modified audio playback signals. Corresponding audio device playback sound may be provided by at least first and second audio devices. At least one microphone may detect at least the first audio device playback sound and the second audio device playback sound and may generate corresponding microphone signals. Audio data may be extracted from the microphone signals in at least the first frequency range, to produce extracted audio data. A far-field audio environment impulse response and/or audio environment noise may be estimated based, at least in part, on the extracted audio data.

Abstract: The present systems, devices, and methods relate to managing shared vehicle access. Vehicle access can be provided to a candidate user based on whether the user is included in a list of at least one user associated with a respective virtual key. Virtual keys can be created, or lists of at least one user can be updated to include the candidate user, to in turn provide vehicle access. Virtual keys can be stored in a plurality of virtual key slots, with vehicle access being provided based on a virtual key stored in an active key slot. Status reports can be sent to a reservation management device, for updating virtual keys or lists of at least one user.

Abstract: Methods, apparatus, systems and articles of manufacture are disclosed for electric motorized wheel assemblies. An example wheel assembly for use with an electric vehicle disclosed herein includes an electric motor, a suspension assembly, and a frame mounting interface to attach the wheel assembly to a frame of the electric vehicle.

Abstract: A system providing various improved processing techniques for haptic feedback is described. An acoustic field is defined by one or more control points in a space within which the acoustic field may exist. Each control point is assigned an amplitude value equating to a desired amplitude of the acoustic field at the control point. Transducers are then controlled to create an acoustic field exhibiting the desired amplitude at each of the control points. When human skin interacts with the acoustic field, vibrations of the skin are interpreted by mechanoreceptors being excited and sending signals to the brain via the nervous system. Improved processing techniques allow for more efficient real-world operation.

Abstract: Apparatuses, systems, and techniques to optimize performance of a processor group. In at least one embodiment, a method increases a processor's clock frequency based, at least in part, on performance of other processors in a group.

Abstract: An insert for an arthropod trapping device. The insert comprising a substrate and a frame for supporting the substrate, where a surface of the substrate has an adhesive disposed thereon, an optional mounting bracket spaced apart from the adhesive surface of the insert and located at a first end of the insert, and an optional graspable tab extending from the frame at a second end of the insert.

Abstract: A variable compression cushion for eyewear includes a lattice structure made up of lattice cells defined by lattice elements. The parameters of the lattice structure may be configured to create a desired compressibility in the cushion. Different zones of the cushion may have different compressibility. The variable compressibility enables the cushion to be configured to optimize the face pressure experienced by a user when the eyewear is worn to enhance the comfort of the user. Some embodiments of the cushion also include structures to improve ventilation through the cushion. Some embodiments of the cushion also include structures that channel moisture away from the portion of the cushion that contacts the face of the user to improve user comfort.

Abstract: An apparatus includes a memory and a processor. The memory stores descriptions of known vulnerabilities and information generated by a monitoring subsystem. Each description of a known vulnerability identifies software components that are associated with the known vulnerability. The monitoring subsystem monitors software programs that are installed within a computer system. The information includes descriptions of issues that are associated with the software programs. The processor generates a set of mappings, based on a comparison between the text describing the known software vulnerabilities and the text describing the issues. Each mapping associates a software program that is associated with an issue with a known software vulnerability. The processor also uses a machine learning algorithm to predict that a given software program is associated with a particular software vulnerability.

Abstract: A computer-implemented method, when executed by data processing hardware of a robot having an articulated arm and a base, causes data processing hardware to perform operations. The operations include determining a first location of a workspace of the articulated arm associated with a current base configuration of the base of the robot. The operations also include receiving a task request defining a task for the robot to perform outside of the workspace of the articulated arm at the first location. The operations also include generating base parameters associated with the task request. The operations further include instructing, using the generated base parameters, the base of the robot to move from the current base configuration to an anticipatory base configuration.

Abstract: This disclosure relates to a climate controlled front trunk. In some aspects, the techniques described herein relate to a motor vehicle, including: a climate control system; and a front trunk establishing a cargo space, wherein the front trunk is configured to receive thermally conditioned air from the climate control system.

Abstract: This disclosure relates to a front trunk including a closure providing increased headroom and shade. In some aspects, the techniques described herein relate to a motor vehicle, including: a front trunk establishing a cargo space; and a closure assembly configured to move between a closed position and an open position to selectively cover and uncover the front trunk, wherein the closure assembly includes a hood section and a grille section, wherein, when the closure assembly is not in the closed position, the grille section is rotatable relative to the hood section in a direction away from a ground surface.

Abstract: A hybrid radiation detector is described comprising a first energy discriminating detector element selected to be sensitive to incident radiation of a lower energy range and a second detector element selected to be sensitive to incident radiation of a higher energy rage and a second detector element. In embodiments, a first detector element comprises a semiconductor detector; and a second detector element comprises a scintillator detector. The first detector element may thus be suitable to be more responsive to radiation in a first, lower energy range and/or configured and arranged to collect incident radiation emergent from a target of such energy that the photoelectric effect predominates as an attenuation mode in the target; and the second detector element may thus be suitable to be more responsive to radiation in a second, higher energy range and/or configured and arranged to collect incident radiation of a generally higher energy.

Abstract: An example method of automatically deploying a containerized workload on a hypervisor based device is provided. The method generally includes booting the device running a hypervisor, in response to booting the device: automatically obtaining, by the device, one or more intended state configuration files from a server external to the device, the one or more intended state configuration files defining a control plane configuration for providing services for at least deploying and managing the containerized workload and workload configuration parameters for the containerized workload; deploying a control plane pod configured according to the control plane configuration; deploying one or more worker nodes based on the control plane configuration, and deploying one or more workloads identified by the workload configuration parameters on the one or more worker nodes.

Abstract: To resolve an issue related to the calibration of optical cameras in transducer-based mid-air haptic systems, the magnification of the motion induced on an optical camera by an acoustic field modulated at specific frequencies reveals very small temporal variations in video frames. This quantized distortion is used to compare different acoustic fields and to solve the calibration problem in an automatized manner. Further, mechanical resonators may be excited by ultrasound when it is modulated at the resonant frequency. When enough energy is transferred and when operating at the correct frequency, a user in contact with the device can feel vibration near areas of largest displacement. This effect can be exploited to create devices which can produce haptic feedback while not carrying a battery or exciter when in the presence of an ultrasonic source.

Abstract: An acoustic field may be produced from a transducer array having known relative positions and orientations In this acoustic field, one or more control points may be defined. An amplitude may be assigned to the control point. Mid-air haptic effect for a virtual object on a human body part may be generated by moving the control point in a single closed curve comprising a plurality of curve segments. The single closed curve traverses at least one location where the human body part intersects with the virtual object. Additionally, a user may interact with virtual three-dimensional content using the user's hands while a tracking system monitoring the user's hands, a physics engine updates the properties of the virtual three-dimensional content and a haptic feedback system provides haptic information to the user.

Abstract: A recommendation system integrated with a content management system (CMS). The CMS stores instances of shared content objects and coordinates user interactions by and between a plurality of CMS users. Shared content objects are divided into a plurality of portions, after which any user interactions over the various portions of the content object are observed and analyzed. User interest inferences are drawn from analysis of the observed user interactions taken user over respective particular portions of the content object. Based on the inferred user interests, fine-grained recommendations are formed and propagated. Some fine-grained recommendations refer to further content objects (e.g., content objects of different types). Some fine-grained recommendations are propagated to other CMS users (e.g., to a plurality of CMS users that are related in some way). The fine-grained recommendations refer to one or more specific portions of a content object as well as to the content object itself.

Abstract: The present systems, devices, and methods relate to managing shared vehicle access. Vehicle access can be provided to a candidate user based on whether the user is included in a list of at least one user associated with a respective virtual key. Virtual keys can be created, or lists of at least one user can be updated to include the candidate user, to in turn provide vehicle access. Virtual keys can be stored in a plurality of virtual key slots, with vehicle access being provided based on a virtual key stored in an active key slot. Status reports can be sent to a reservation management device, for updating virtual keys or lists of at least one user.

Abstract: A valve housing (1) has first and third openings (1.1, 1.3), and first and second actuating elements (6.1, 6.2) that are movable along a longitudinal axis of the housing (1). A return element (5) is between the actuating elements (6.1, 6.2), and exerts a force to keep the actuating elements (6.1, 6.2) in a rest position to close or open the first and third openings (1.1. 1.3). First and second wires (4.1, 4.2) are formed from a shape memory alloy. The first wire (4.1) is on the first actuating element (6.1) and the second wire (4.2) is on the second actuating element (6.2). An electric current to the first or second wire (4.1, 4.2) contracts the respective wire (4.1, 4.2) and moves the corresponding actuating element (6.1, 6.2) into an activated position against the force exerted by the return element (5).

Abstract: Systems and methods are described for pre-authentication access request screening. A server computer may receive a request for access to a resource comprising access data. The server computer may transmit, to an authentication computer, an authentication request message comprising at least a subset of the access data and receive an authentication response message comprising authentication data. The server computer may determine an access score based on the authentication data. Alternatively, the server computer may determine the access score based on the access data without using/receiving authorization data. The server computer may generate an access indicator based on the access score. The server computer may prepare and transmit an authorization request message comprising the access indicator to an authorization computer. The authorization computer may approve or decline the access to the resource based on the access indicator.