Patents by Inventor Bernd Kaiser
Bernd Kaiser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200230334Abstract: The present invention provides a single-dose powder-medication inhaler (10) for nasal application, comprising a flat inhaler housing consisting of two flat housing parts (1, 2) connected to one another along a connecting plane (E). Formed in the two flat housing parts are: a medication chamber (11) having at least one powder receiving hollow (11?); an air inlet opening (14); and an air channel delimited by walls (7), the air channel extending from the air inlet opening (14), via the medication chamber (11) to a discharge opening (12). According to the invention the air inlet opening (14) does not lie on a side facing away from the discharge opening (12), whereby the air channel provides a direction change of an air flow through the air inlet opening (14) relative to the discharge opening (12). The outlet section (13) of the air channel between the medication chamber (11) and the discharge opening (12) has more than one bend (6).Type: ApplicationFiled: June 22, 2018Publication date: July 23, 2020Inventors: Klaus-Dieter Beller, Bernd Kaiser
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Patent number: 10669296Abstract: This invention features compounds that modulate the activity of liver X receptors, pharmaceutical compositions including the compounds of the invention, and methods of utilizing those compositions for modulating the activity of liver X receptors in the treatment of cancer.Type: GrantFiled: January 9, 2015Date of Patent: June 2, 2020Assignee: Rgenix, Inc.Inventors: Eduardo J. Martinez, Bernd Kaiser, Sohail F. Tavazoie, Isabel Kurth, Foster Casimir Gonsalves, David M. Darst, Jr., Masoud Fakhr Tavazoie
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Patent number: 10605717Abstract: An apparatus for analyzing urine, including: a feeding and discharging device that delivers a quantity of urine into an analysis chamber of a urine test strip and discharges a quantity of urine from an analysis chamber of a urine test strip, the analysis chamber having an analysis zone. The feeding and discharging device includes a movably mounted feeding and/or discharging element for delivering a quantity of urine into a delivery zone in the analysis chamber and/or discharging a quantity of urine from a discharge zone in the analysis chamber. A detection device detects an at least sectoral variation of an optically detectable parameter, which varies in an optically detectable manner in accordance with the composition of a quantity of urine that contacts the analysis zone and produces detection data describing at least one optically detected parameter in the analysis zone or a variation of such a parameter.Type: GrantFiled: October 5, 2015Date of Patent: March 31, 2020Assignee: DURAVIT AKTIENGESELLSCHAFTInventors: Bernd Spangenberg, Dirk Jansen, Bernd Kaiser
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Publication number: 20170284925Abstract: An apparatus for analyzing urine, including: a feeding and discharging device that delivers a quantity of urine into an analysis chamber of a urine test strip and discharges a quantity of urine from an analysis chamber of a urine test strip, the analysis chamber having an analysis zone. The feeding and discharging device includes a movably mounted feeding and/or discharging element for delivering a quantity of urine into a delivery zone in the analysis chamber and/or discharging a quantity of urine from a discharge zone in the analysis chamber. A detection device detects an at least sectoral variation of an optically detectable parameter, which varies in an optically detectable manner in accordance with the composition of a quantity of urine that contacts the analysis zone and produces detection data describing at least one optically detected parameter in the analysis zone or a variation of such a parameter.Type: ApplicationFiled: October 5, 2015Publication date: October 5, 2017Inventors: Bernd SPANGENBERG, Dirk JANSEN, Bernd KAISER
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Publication number: 20170066791Abstract: This invention features compounds that modulate the activity of liver X receptors, pharmaceutical compositions including the compounds of the invention, and methods of utilizing those compositions for modulating the activity of liver X receptors in the treatment of cancer.Type: ApplicationFiled: January 9, 2015Publication date: March 9, 2017Inventors: Eduardo J. MARTINEZ, Bernd KAISER, Sohail F TAVAZOIE, Isabel KURTH, Foster Casimir GONSALVES, David M. DARST, Masoud Fakhr TAVAZOIE
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Publication number: 20110213029Abstract: There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.Type: ApplicationFiled: May 6, 2011Publication date: September 1, 2011Applicants: Schering Corporation, Pharmacopeia Drug DiscoveryInventors: Arthur G. Taveras, Cynthia J. Aki, Richard W. Bond, Jianping Chao, Michael Dwyer, Johan A. Ferreira, Jianhua Chao, Younong Yu, John J. Baldwin, Bernd Kaiser, Ge Li, J. Robert Merritt, Purakkattle J. Biju, Kingsley H. Nelson, JR., Laura L. Rokosz, Gaifa Lai, James P. Jakway, Minglang Wu, Evan A. Hecker, Daniel Lundell, Jay S. Fine
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Patent number: 7964646Abstract: There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.Type: GrantFiled: August 8, 2006Date of Patent: June 21, 2011Assignees: Schering Corporation, Pharmacopeia Drug DiscoveryInventors: Arthur G. Taveras, Cynthia J. Aki, Richard W. Bond, Jianping Chao, Michael Dwyer, Johan A. Ferreira, Jianhua Chao, Younong Yu, John J. Baldwin, Bernd Kaiser, Ge Li, J. Robert Merritt, Purakkattle J. Biju, Kingsley H. Nelson, Jr., Laura L. Rokosz, Gaifa Lai
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Patent number: 7947720Abstract: There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.Type: GrantFiled: January 13, 2009Date of Patent: May 24, 2011Assignees: Schering Corporation, Pharmacopeia Drug DiscoveryInventors: Arthur G. Taveras, Cynthia J. Aki, Richard W. Bond, Jianping Chao, Michael Dwyer, Johan A. Ferreira, Jianhua Chao, Younong Yu, John J. Baldwin, Bernd Kaiser, Ge Li, J. Robert Merritt, Purakkattle J. Biju, Kingsley H. Nelson, Jr., Laura L. Rokosz
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Publication number: 20090306079Abstract: There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.Type: ApplicationFiled: January 13, 2009Publication date: December 10, 2009Inventors: Arthur G. Taveras, Cynthia J. Aki, Richard W. Bond, Jianping Chao, Michael Dwyer, Johan A. Ferreira, Jianhua Chao, Younong Yu, John J. Baldwin, Bernd Kaiser, Ge Li, J. Robert Merritt, Purakkattle J. Biju, Kingsley H. Nelson, JR., Laura L. Rokosz, Gaifa Lai, James P. Jakway, Minglang Wu, Evan A. Hecker, Daniel Lundell, Jay S. Fine
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Publication number: 20070043056Abstract: Novel 5-substituted-2-arylpyrazine compounds are provided. Such compounds can act as selective modulators of CRF receptors. The 5-substituted-2-arylpyrazine compounds provided herein are useful in the treatment of a number of CNS and periphereal disorders, particularly stress, anxiety, depression, cardiovascular disorders, and eating disorders. Methods of treatment of such disorders and well as packaged pharmaceutical compositions are also provided. Compounds provided are also useful as probes for the localization of CRF receptors and as standards in assays for CRF receptor binding. Methods of using the compounds in receptor localization studies are given.Type: ApplicationFiled: October 23, 2006Publication date: February 22, 2007Applicant: Neurogen CorporationInventors: Taeyoung Yoon, Ping Ge, Stephane De Lombaert, Raymond Horvath, Dario Doller, Kevin Hodgetts, Lu Yan Zhang, Bernd Kaiser, Xuechun Zhang, Cunyu Zhang, Jim Darrow, Yasuchika Yamaguchi
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Patent number: 7179807Abstract: Novel 5-substituted-2-arylpyrazine compounds are provided. Such compounds can act as selective modulators or CRF receptors. Compounds of the invention are provided by the following formula: The 5-substituted-2-arylpyrazine compounds provided herein are useful in the treatment of a number of CNS and periphercal disorders, particularly stress, anxiety, depression, cardiovascular disorders, and eating disorders. Methods of treatment of such disorders and well as packaged pharmaceutical compositions are also provided. Compounds provided are also useful as probes for the localization of CRF receptors and as standards in assays for CRF receptor binding. Methods of using the compounds in receptor localization studies are given.Type: GrantFiled: August 20, 2003Date of Patent: February 20, 2007Assignee: Neurogen CorporationInventors: Taeyoung Yoon, Ping Ge, Stéphane De Lombaert, Raymond F. Horvath, Dario Doller, Kevin J. Hodgetts, Lu Yan Zhang, Bernd Kaiser, Xuechun Zhang, Yasuchika Yamaguchi, Cunyu Zhang, Jim Darrow
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Publication number: 20070021494Abstract: There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.Type: ApplicationFiled: August 8, 2006Publication date: January 25, 2007Inventors: Arthur Taveras, Cynthia Aki, Richard Bond, Jianping Chao, Michael Dwyer, Johan Ferreira, Jianhua Chao, Younong Yu, John Baldwin, Bernd Kaiser, Ge Li, J. Merritt, Purakkattle Biju, Kingsley Nelson, Laura Rokosz, Gaifa Lai, James Jakway, Minglang Wu, Evan Hecker, Daniel Lundell, Jay Fine
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Patent number: 7132445Abstract: There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.Type: GrantFiled: July 30, 2003Date of Patent: November 7, 2006Assignees: Schering Corporation, Pharmacopeia Drug Discovery, Inc.Inventors: Arthur G. Taveras, Cynthia J. Aki, Richard W. Bond, Jianping Chao, Michael Dwyer, Johan A. Ferreira, Jianhua Chao, Younong Yu, John J. Baldwin, Bernd Kaiser, Ge Li, J. Robert Merritt, Purakkattle J. Biju, Kingsley H. Nelson, Jr., Laura L. Rokosz, James P. Jakway, Gaifa Lai, Minglang Wu, Evan A. Hecker, Daniel Lundell, Jay S. Fine
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Publication number: 20060199823Abstract: Substituted heteroaryl fused pyridine, pyrazine, and pyrimidine compounds that act as selective modulators of CRF 1 receptors are provided. These compounds are useful in the treatment of a number of CNS and periphereal disorders, particularly stress, anxiety, depression, cardiovascular disorders, and eating disorders. Methods of treatment of such disorders and well as packaged pharmaceutical compositions are also provided. Compounds of the invention are also useful as probes for the localization of CRF receptors and as standards in assays for CRF receptor binding. Methods of using the compounds in receptor localization studies are given.Type: ApplicationFiled: March 24, 2006Publication date: September 7, 2006Applicant: Neurogen CorporationInventors: Ping Ge, Raymond Horvath, Lu Zhang, Yasuchika Yamaguchi, Bernd Kaiser, Xuechun Zhang, Suoming Zhang, He Zhao
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Publication number: 20050113379Abstract: Substituted heteroaryl fused pyridine, pyrazine, and pyrimidine compounds that act as selective modulators of CRF 1 receptors are provided. These compounds are useful in the treatment of a number of CNS and periphereal disorders, particularly stress, anxiety, depression, cardiovascular disorders, and eating disorders. Methods of treatment of such disorders and well as packaged pharmaceutical compositions are also provided. Compounds of the invention are also useful as probes for the localization of CRF receptors and as standards in assays for CRF receptor binding. Methods of using the compounds in receptor localization studies are given.Type: ApplicationFiled: September 3, 2004Publication date: May 26, 2005Inventors: Ping Ge, Raymond Horvath, Lu Yan Zhang, Yasuchika Yamaguchi, Bernd Kaiser, Xuechun Zhang, Suoming Zhang, He Zhao, Stanly John, Neil Moorcroft, Greg Shutske
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Publication number: 20050070542Abstract: 5-aryl-Pyrazolo[4,3-d]pyrimidines, 6-aryl-Pyrazolo[3,4-d]pyrimidines and related compounds, as well as other chemically related compounds, that act as selective modulators of CRF 1 receptors are provided. These compounds are useful in the treatment of a number of CNS and periphereal disorders, particularly stress, anxiety, depression, cardiovascular disorders, and eating disorders. Methods of treatment of such disorders and well as packaged pharmaceutical compositions are also provided. Compounds of the invention are also useful as probes for the localization of CRF receptors and as standards in assays for CRF receptor binding. Methods of using the compounds in receptor localization studies are given.Type: ApplicationFiled: September 3, 2004Publication date: March 31, 2005Inventors: Kevin Hodgetts, Stanly John, Neil Moorcroft, Greg Shutske, Bernd Kaiser, Yasuchika Yamaguchi, Ping Ge, Raymond Horvath
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Publication number: 20040235908Abstract: Disclosed are compounds of the formula: 1Type: ApplicationFiled: June 16, 2004Publication date: November 25, 2004Applicant: Schering CorporationInventors: Arthur G. Taveras, Cynthia J. Aki, Richard W. Bond, Jianping Chao, Michael Dwyer, Johan A. Ferreira, Jonathan A. Pachter, John J. Baldwin, Bernd Kaiser, Ge Li, J. Robert Merritt, Kingsley H. Nelson, Laura L. Rokosz
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Patent number: 6821632Abstract: In a composite of vulcanizable rubber or rubber-like composition with one or more metal reinforcement elements embedded therein, the metal reinforcement element is coated with a polymer or non-cured rubber composition compatible with and co-polymerizable, co-vulcanizable or crosslinkable with said vulcanizable ruber composition to be reinforced, and additionally bearing functional groups either covalently bonding to the metal surface of said reinforcement element or forming covalent bonds with the outward directed first functional groups of a mono- or multimolecular layer of a bifunctional adhesion promoter intercalated between said metal and said coating and bound to said metal by its second functional groups. A cured rubber or rubber-like product, for instance a pneumatic tire, is obtained by vulcanization of such a composite.Type: GrantFiled: April 13, 2001Date of Patent: November 23, 2004Assignee: Continental AktiengesellschaftInventors: Andreas Topp, Bernd Kaiser, Richard Michalitsch, Francis Garnier, Philippe Lang
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Publication number: 20040147559Abstract: There are disclosed compounds of the formula 1Type: ApplicationFiled: July 30, 2003Publication date: July 29, 2004Applicant: Schering Corporation and Pharmacopeia, Inc.Inventors: Arthur G. Taveras, Cynthia J. Aki, Richard W. Bond, Jianping Chao, Michael Dwyer, Johan A. Ferreira, Jianhua Chao, Younong Yu, John J. Baldwin, Bernd Kaiser, Ge Li, J. Robert Merritt, Purakkattle J. Biju, Kingsley H. Nelson, Laura L. Rokosz, James P. Jakway, Gaifa Lai, Minglang Wu, Evan A. Hecker, Daniel Lundell, Jay S. Fine
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Publication number: 20040106794Abstract: There are disclosed compounds of the formula 1Type: ApplicationFiled: September 11, 2002Publication date: June 3, 2004Applicant: Schering CorporationInventors: Arthur G. Taveras, Cynthia J. Aki, Richard W. Bond, Jianping Chao, Michael Dwyer, Johan A. Ferreira, Jianhua Chao, Younong Yu, John J. Baldwin, Bernd Kaiser, Ge Li, J. Robert Merritt, Purakkattle J. Biju, Kingsley H. Nelson, Laura L. Rokosz