Patents by Inventor Bernhard A. Fischer

Bernhard A. Fischer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8372799
    Abstract: A protein which is composed N-terminally of one or several C-terminal parts of the amino acid sequence of the mature tumor necrosis factor and C-terminally of one or several N-terminal parts of the amino acid sequence of the mature tumor necrosis factor, which activates epithelial ion channels and improves the lung function and which can be used for the manufacture of medicaments for the treatment of diseases associated with the lung function, such as oedemas.
    Type: Grant
    Filed: December 12, 2008
    Date of Patent: February 12, 2013
    Assignee: Apeptico Forschung und Entwicklung GmbH
    Inventors: Bernhard Fischer, Rudolf Lucas
  • Publication number: 20120317068
    Abstract: A method is disclosed for generating a set of optimal rules and parameters for use by an evaluation engine on a volume of information extracted from a stream of IP packets associated with a web browsing session conducted over a network in order to filter user-initiated traffic flowing across the network from non-user-initiated traffic. Deep packet inspection is performed to extract the volume of information from the stream that conforms to at least one discrimination criteria. An initial iteration of application of the evaluation engine to the volume is performed by selecting initial discrimination criteria and rules for generating the filtered results and a distance between the filtered results and known actual user-initiated traffic is measured. Subsequent iterations of application of the evaluation engine to the volume are performed by changing the discrimination criteria and/or rules until there is no significant improvement in the measured distance.
    Type: Application
    Filed: June 9, 2011
    Publication date: December 13, 2012
    Inventors: Thomas Walter Ruf, Bernhard Fischer-Wuenschel, Renate Wendlik
  • Publication number: 20120317151
    Abstract: A network intelligence solution (“NIS”) is arranged to access a stream of IP (Internet Protocol) packets associated with communications over a network between a network access device and a server. The NIS performs deep packet inspection (“DPI”) to extract a volume of information from the accessed stream that conforms to at least one discrimination criteria and further utilizes an evaluation model that applies rules to filter the volume of information to distinguish user-initiated traffic flowing across the network from non-user-initiated traffic. The filtered results are written to a database and may be analyzed to determine network usage and/or other network characteristics.
    Type: Application
    Filed: June 9, 2011
    Publication date: December 13, 2012
    Inventors: Thomas Walter Ruf, Bernhard Fischer-Wuenschel, Renate Wendlik
  • Publication number: 20120018542
    Abstract: A stroke translator or an injector having a solid-state actuator for generating a stroke and a hydraulic system for the hydraulic transmission of the stroke of the solid-state actuator to a control element such as a jet needle of a valve. The hydraulic system has hydraulic volumes hermetically sealed to the outside by metal bellows and constitute a hydraulic bearing with compensation for play. The advantages over known hydraulic levers are such that a complete metal seal is provided, and that a lower-wear design can be realized. Furthermore, a modular structure can be produced.
    Type: Application
    Filed: February 25, 2010
    Publication date: January 26, 2012
    Applicant: SIEMENS AKTIENGESELLSCHAFT
    Inventors: Georg Bachmaier, Gerit Ebelsberger, Bernhard Fischer, Matthias Gerlich, Michael Höge, Wolfgang Zöls
  • Publication number: 20110319316
    Abstract: A peptide is described, which consists of 7-17 adjacent amino acids and comprises the hexamer TX EX X E, wherein X, X and X can be any natural or non-natural amino acid, wherein the peptide has no TNF receptor binding activity and is cyclized, for the prevention and treatment of hyperpermeability of epithelial cells and endothelial cells.
    Type: Application
    Filed: March 5, 2010
    Publication date: December 29, 2011
    Applicant: APEPTICO FORSCHUNG UND ENTWICKLUNG GMBH
    Inventors: Bernhard Fischer, Rudolf Lucas
  • Publication number: 20110269032
    Abstract: A combustor generates and supplies hot combustion gases to a fuel reformer. The combustor includes a housing defining a combustion chamber. The combustor also includes a fuel vaporizer having a fuel tube with an electric heating element. The fuel tube is positioned such that a portion thereof extends into the combustion chamber and is exposed to the hot combustion gases exiting the combustion chamber. An electric current is supplied to the electric heating element to vaporize the liquid fuel within the fuel tube when the temperature within the combustion chamber is below is a predetermined temperature. Substantially no electric current is supplied to the electric heating element when the temperature within the combustion chamber is at least the predetermined temperature and the hot combustion gases passing over the portion of the fuel tube extending into the combustion chamber vaporize the liquid fuel within the fuel tube.
    Type: Application
    Filed: December 10, 2010
    Publication date: November 3, 2011
    Applicant: DELPHI TECHNOLOGIES, INC.
    Inventors: Bernhard A. Fischer, Duane E. Jones
  • Patent number: 8038119
    Abstract: A metering device has an actuating unit within a housing in which an actuator is inserted and a hydraulic compensating element. The hydraulic compensating element is connected to the actuator and can be filled with a fluid when subjected to pressure. A first end of the actuator is provided with a first end cap. The metering device further has a stop that is disposed on the housing in the form of a seat, faces the first end cap, and defines a stopping position for the first end cap. The stop maintains a maximum distance between a sealing element and the end cap, the distance being smaller than the actuator traveling distance such that the actuator stroke beyond the end cap is sufficient for opening the valve. The first end cap hits the stop when moving in the direction of the hydraulic compensating element such that the movement is blocked.
    Type: Grant
    Filed: September 10, 2004
    Date of Patent: October 18, 2011
    Assignee: Siemens Aktiengesellschaft
    Inventors: Georg Bachmaier, Bernhard Fischer, Bernhard Gottlieb, Andreas Kappel, Tim Schwebel
  • Publication number: 20110105414
    Abstract: A protein selected from the amino acid sequence of the region valine Val(91) to glycine Gly(l21) of the mature human tumour necrosis factor, or a portion thereof, with the proviso that the protein comprises at least the amino acid sequence of the region lysine Lys(98) to glutamic acid Glu(116), with the cysteine Cys(101) being replaced by a glycine and an amide bond being formed between the amino group of the side chain of the lysine Lys(98) and the carboxyl group of the side chain of the glutamic acid Glu(116), which activates epithelial ion channels and improves the lung function and which can be used for the manufacture of medicaments for the treatment of diseases associated with the lung function, such as oedemas.
    Type: Application
    Filed: December 12, 2008
    Publication date: May 5, 2011
    Applicant: APEPTICO FORSCHUNG UND ENTWICKLUNG GMBH
    Inventors: Bernhard Fischer, Rudolf Lucas
  • Patent number: 7886993
    Abstract: An injection valve for injecting fuel comprises a valve housing (1) inside of which a drive unit (15) controls the movement of a valve needle (5) that is pretensioned by a spring (11). The injection valve also comprises a main chamber (27), which is provided inside the valve housing, is filled with fuel and accommodates the valve needle (5), and comprises a hydraulic bearing for the drive unit (15). The hydraulic bearing has a hydraulic chamber (29) that is connected to the main chamber (27), whereby fuel serves as the operating substance of the hydraulic bearing.
    Type: Grant
    Filed: August 23, 2004
    Date of Patent: February 15, 2011
    Assignee: Siemens Aktiengesellschaft
    Inventors: Georg Bachmaier, Bernhard Fischer, Bernhard Gottlieb, Andreas Kappel, Hans Meixner, Enrico Ulivieri
  • Publication number: 20110021411
    Abstract: A protein which is composed N-terminally of one or several C-terminal parts of the amino acid sequence of the mature tumour necrosis factor and C-terminally of one or several N-terminal parts of the amino acid sequence of the mature tumour necrosis factor, which activates epithelial ion channels and improves the lung function and which can be used for the manufacture of medicaments for the treatment of diseases associated with the lung function, such as oedemas.
    Type: Application
    Filed: December 12, 2008
    Publication date: January 27, 2011
    Applicant: APEPTICO FORSCHUNG UND ENTWICKLUNG GMBH
    Inventors: Bernhard Fischer, Rudolf Lucas
  • Patent number: 7858214
    Abstract: In an SOFC stack system, wherein a CPOx reformer supplies reformate to the stack, a portion of the anode tail gas is recycled directly into the anode inlet of the stack, such that the fuel reaching the anodes is a mixture of fresh reformate and recycled anode tail gas and is present at a sufficiently high temperature that endothermic reforming of residual hydrocarbons from the CPOx reformer occurs within the stack. Preferably, an amount of secondary non-reformed fuel is also added to optimize the fuel mixture presented for internal reforming. The anode tail gas is hot, at the stack temperature of 750-800° C., which allows for the mixture of anode tail gas and secondary fuel to be mixed and reacted in a clean-up catalyst to react higher hydrocarbons in the secondary fuel, without additional oxygen, prior to being mixed with reformate and sent to the stack.
    Type: Grant
    Filed: September 21, 2005
    Date of Patent: December 28, 2010
    Assignee: Delphi Technologies, Inc.
    Inventors: Sean M. Kelly, Bernhard Fischer
  • Publication number: 20100143755
    Abstract: A planar endothermic reformer assembly comprising only a few macrochannels rather than many microchannels as in the prior art. The macrochannels are arranged alternately in a stack for reforming and hot gas flow in a cross-flow reformer/heat exchanger. The assembly includes four manifolds. An external combustor supplies heat to the hot gas macrochannels in the reformer/heat exchanger stack for endothermic reforming, resulting in low temperature gradients in the reforming macrochannels. The macrochannels, having no dimension less than 2.0 mm, contain metal substrates for heat transfer as well as for support for the catalytic washcoat and may comprise packs of corrugated sheet metal such as Haynes or Inconell; packs of wire mesh; metallic foam made of Fecralloy, Haynes, Inconel, or higher conductivity material; or stacks of metallic felt material. The metallic substrates are brazed into the reforming channels and the hot flow channels to ensure maximum heat transfer for highest reforming efficiencies.
    Type: Application
    Filed: June 24, 2009
    Publication date: June 10, 2010
    Inventors: Bernhard A. Fischer, David J. Ranelli, David Schumann
  • Publication number: 20100050929
    Abstract: Coil arrangement for crystal pulling comprising two coils, wherein at least one of said two coils is arranged in a way to substantially surround the crystal and/or the fluid the crystal is pulled from. Method of forming a crystal comprising the steps of providing a fluid the crystal is pulled from, and providing two coils, wherein at least one of said two coils is arranged in a way to substantially surround the crystal and/or the fluid, and pulling the crystal from the fluid.
    Type: Application
    Filed: August 27, 2008
    Publication date: March 4, 2010
    Applicant: ACCEL INSTRUMENTS GMBH
    Inventors: Achim Hobl, Bernhard Fischer
  • Patent number: 7669783
    Abstract: The invention relates to an injection valve which has a piezo actuator that is functionally connected to a nozzle needle by a hydraulic transmission device. The hydraulic transmission device is connected to a pressure reservoir by a sealing gap so that the pressure differences between the pressure reservoir and a hydraulic chamber of the hydraulic transmission device are compensated in the long term.
    Type: Grant
    Filed: February 11, 2003
    Date of Patent: March 2, 2010
    Assignee: Siemens Aktiengesellschaft
    Inventors: Bernhard Fischer, Bernhard Gottlieb, Andreas Kappel, Hans Meixner, Randolf Mock
  • Patent number: 7648958
    Abstract: There is disclosed a method of recovering factor VIII/vWF-complex which is characterized in that factor VIII/vWF-complex from a protein solution is bound to a cation exchanger and is recovered by step-wise elution of factor VIII/vWF-complex, which particularly contains high-molecular vWF multimers, as well as a factor VIII/vWF-complex obtainable by means of cation exchange chromatography.
    Type: Grant
    Filed: February 27, 2004
    Date of Patent: January 19, 2010
    Assignee: Baxter Innovations GmbH
    Inventors: Artur Mitterer, Bernhard Fischer, Oyvind L. Schönberger, Kathrin Thomas-Urban, Friedrich Dorner, Johann Eibl
  • Patent number: 7638923
    Abstract: The invention relates to a method and a control unit for operating a hydraulic injection valve, which comprises at least one piezoelectric actuator (2), a displaceable component (3) and a hydraulic element (9) such as bearing or a transmission system. The use of a drive voltage (U) modifies the length of an actuator (2), which makes it possible to control the stroke of the displaceable component (a valve needle 3). The inventive control unit (10) produces a polarizing voltage (UB) which pre-stresses the actuator (2) and whose polarization direction is opposite to the polarization direction of said actuator (2). Said invention makes it possible to obtain the greater modification of the length when the actuator (2) operates in the polarization direction than the drive voltage starts at 0 volts, as it was in practice before. Said invention makes it possible to reduce energy consumption.
    Type: Grant
    Filed: September 3, 2003
    Date of Patent: December 29, 2009
    Assignee: Siemens Aktiengesellschaft
    Inventors: Georg Bachmaier, Bernhard Fischer, Bernhard Gottlieb, Andreas Kappel, Tim Schwebel
  • Patent number: 7498146
    Abstract: There are disclosed a stable factor VIII/vWF-complexes, particularly comprising high-molecular vWF multimers, being free from low-molecular vWF molecules and from proteolytic vWF degradation products, as well as methods of producing these complexes.
    Type: Grant
    Filed: May 19, 2005
    Date of Patent: March 3, 2009
    Assignee: Baxter Innovations GmbH
    Inventors: Bernhard Fischer, Artur Mitterer, Friedrich Dorner, Johann Eibl
  • Publication number: 20090042071
    Abstract: A catalytic reformer assembly including a reactor comprising a plurality of parallel tubes arranged within a tubular housing. A metal substrate, formed preferably as a metal foam lattice, is brazed to the tubes on both their inside and outside surfaces. A catalytic washcoat is applied to the metal substrate within the tubes, defining thereby the tubes as individual catalytic reforming reactors. Endothermic reforming reactions within the tubes are supported by heat from hot combustor exhaust flowing around the tubes in contact with the augmenting heat transfer metal substrates outside the tubes. Radial temperature gradients are small because of excellent heat transfer across the tube walls, resulting in excellent mechanical stability of the washcoat on the metal substrate. Preferably, the tubes are formed of Inconel 625 and the metal substrate is formed of Fecralloy®, a high temperature alloy having excellent thermal conductivity and oxidation resistance.
    Type: Application
    Filed: August 7, 2007
    Publication date: February 12, 2009
    Inventors: Bernhard A. Fischer, Diane M. England, David J. Ranelli
  • Publication number: 20080292922
    Abstract: An SOFC fuel cell stack system including means for recycling a portion of the SOFC anode tailgas into the inlet of a hydrocarbon reformer supplying reformate to the stack. Recycle means includes a pump. A first heat exchanger ahead of the pump cools the tail gas via heat exchange with incoming cathode air, allowing use of an inexpensive pump. To facilitate endothermic or steam reforming of hydrocarbons, CO2, and water in the later portions of the reformer, heat is added back into the tailgas recycle by installing a second heat exchanger or an electric heater downstream of the pump. Air and fuel being supplied to the reformer also are preheated, and reforming air flow may be increased to increase exothermic activity in the early portions of the reformer to permit recycling of large percentages of tailgas such that greater overall reformer efficiencies are achievable.
    Type: Application
    Filed: May 22, 2007
    Publication date: November 27, 2008
    Inventor: Bernhard A. Fischer
  • Publication number: 20080253938
    Abstract: A catalytic reformer assembly including a liquid hydrocarbon fuel vaporizer comprising a combustion zone and a mixing zone ahead of the reformer. Fuel flow is divided between a principal flow directed to the mixing zone and a secondary flow directed to the combustion zone. Air flow is also divided between a principal flow to the mixing zone and a secondary flow to the combustor. The principal air flow is mixed with the combustor effluent together with anode tailgas recycle (“recycle”) when it becomes available. The flow of recycle is also divided into principal and secondary flows. By varying component flows, the mixture temperature can be controlled. The principal fuel flow is injected into the hot mixture of combustion products, air, and recycle in the mixing zone.
    Type: Application
    Filed: April 13, 2007
    Publication date: October 16, 2008
    Inventor: Bernhard A. Fischer