Abstract: A driver includes a low-resistance charging path between a supply voltage rail and a first output node, a high-resistance charging path between the supply voltage rail and the first output node, an inverter coupled to the first output node and configured to enable and disable the low-resistance charging path, and a high-resistance discharging path between the first output node and a second output node. The first output node is coupled to a control terminal of a pass gate transistor in some implementations. The low-resistance charging path charges a voltage on the first output node to a threshold voltage of the pass gate transistor, and the high-resistance charging path charges the voltage on the first output node greater than the threshold voltage of the pass gate transistor. The high-resistance discharging path discharges the voltage on the first output node.

Abstract: The invention relates to a dental tool having a shank region, which is formed for coupling to a dental handpiece, and also having a work region, which is connected to the shank region. In this case, the shank region of the dental tool is formed so that there is the possibility of latchable insertion and removal without actuation. In particular, at least the shank region can consist of plastics material. As a result, inter alia facilitated handling of the tool and inexpensive production of the tool are rendered possible.

Abstract: The invention relates to a dental tool having a shank region, which is formed for coupling to a dental handpiece, and also having a work region, which is connected to the shank region. In this case, the shank region of the dental tool is formed so that there is the possibility of latchable insertion and removal without actuation. In particular, at least the shank region can consist of plastics material. As a result, inter alia facilitated handling of the tool and inexpensive production of the tool are rendered possible.

Abstract: The invention relates to a dental tool having a shank region, which is formed for coupling to a dental handpiece, and also having a work region, which is connected to the shank region. In this case, the shank region of the dental tool is formed so that there is the possibility of latchable insertion and removal without actuation. In particular, at least the shank region can consist of plastics material. As a result, facilitated handling of the tool and inexpensive production of the tool are rendered possible.

Abstract: Provided herein are methods of treating congenital heart disease in a patient, such as tetralogy of Fallot, with beta blockers to increase cardiomyocyte endowment in the patient and/or to reduce risk of developing complications originating later from heart diseases, such as myocardial infarction, in the patient. Also provided herein are uses for beta blockers for treating congenital heart disease, such as tetralogy of Fallot, in a patient to increase cardiomyocyte endowment in the patient and/or to reduce risk of developing complications originating later from heart diseases, such as myocardial infarction, in the patient.

Abstract: In the case of a dental hand instrument having a grip sleeve and also a head housing arranged at the front end of the grip sleeve for receiving or holding a treatment instrument, the head housing has a substantially cylindrical hollow space which is connected by way of at least one connecting bore to a connection region pointing to the grip sleeve, wherein the connecting bore is coupled, at its end facing the grip sleeve, to a media line extending through the grip sleeve, and wherein the inner wall region of the head housing enclosing the hollow space has a recess into which the connecting bore opens.

Abstract: The invention relates to a dental tool having a shank region, which is formed for coupling to a dental handpiece, and also having a work region, which is connected to the shank region. In this case, the shank region of the dental tool is formed so that there is the possibility of latchable insertion and removal without actuation. In particular, at least the shank region can consist of plastics material. As a result, inter alia facilitated handling of the tool and inexpensive production of the tool are rendered possible.

Abstract: A process and also to a system for cleaning and maintaining a medical hand-held instrument, in particular a dental hand-held instrument, with an elongate grip sleeve in which elements are arranged which pertain to a drive arrangement and which are, in particular, rotatably supported, for example a shaft. For the purpose of cleaning and maintaining the hand-held instrument different media are conducted through it. In this connection a first medium, for example oil, is conducted merely through a power-transmission region surrounding the elements of the drive arrangement, whereas, on the other hand, a second medium, for example a cleaning agent, is conducted additionally also through at least one further cavity within the hand-held instrument.

Abstract: A dental hand instrument having an elongate handle sleeve, at the front end of which there is disposed a tool holder for holding a treatment tool, for example a dental drill, there is disposed inside the handle sleeve a driving mechanism for driving the treatment tool, the driving mechanism having at least two rotatably mounted shafts that are coupled to each other, and a sealing element is disposed in the coupling region of the two shafts inside the handle sleeve.

Abstract: In the case of a dental hand instrument having a grip sleeve and also a head housing arranged at the front end of the grip sleeve for receiving or holding a treatment instrument, the head housing has a substantially cylindrical hollow space which is connected by way of at least one connecting bore to a connection region pointing to the grip sleeve, wherein the connecting bore is coupled, at its end facing the grip sleeve, to a media line extending through the grip sleeve, and wherein the inner wall region of the head housing enclosing the hollow space has a recess into which the connecting bore opens.

Abstract: The present invention provides compositions and methods for increasing proliferation, increasing cell cycle activity, and/or proliferation of postmitotic mammalian differentiated cardiomyocytes. The invention can be used to slow, reduce, or prevent the onset of cardiac damage caused by, for example, myocardial ischemia, hypoxia, stroke, or myocardial infarction in vivo. In addition, the methods and compositions of the invention can be used to enhance proliferation of differentiated cardiomyocytes in vitro and/or ex vivo, which can then be used in tissue grafting.

Abstract: A bearing for rotatably mounting a rotational part, for example a turbine rotor of a dental handpiece, has a plurality of roll bodies, in particular balls, arranged between an inner bearing ring and an outer bearing ring, a cage surrounding the roll bodies in an axial direction, and a locking element for axially locking the bearing rings with respect to each other, wherein the locking element has a ring-like or ring-segment-like securing element fitted on an inner circumference of the outer bearing ring or on an outer circumference of the inner bearing ring in a region of the cage such that the locking element blocks the roll bodies in the axial direction.

Abstract: In a dental, dental-medical or dental-technical handpiece, having an elongate grip sleeve there are provided at the rearward end of the grip sleeve coupling elements for the connection of the handpiece to a supply hose to be connected with a dental supply arrangement, and there are provided at the forward end of the grip sleeve a head section with a tool receiver for mounting a tool to be put into rotation. The handpiece further has an electric motor for driving a tool held by the tool receiver, which motor is completely integrated into the grip sleeve such that grip sleeve and motor form a unit.

Abstract: A process and also to a system for cleaning and maintaining a medical hand-held instrument, in particular a dental hand-held instrument, with an elongate grip sleeve in which elements are arranged which pertain to a drive arrangement and which are, in particular, rotatably supported, for example a shaft. For the purpose of cleaning and maintaining the hand-held instrument different media are conducted through it. In this connection a first medium, for example oil, is conducted merely through a power-transmission region surrounding the elements of the drive arrangement, whereas, on the other hand, a second medium, for example a cleaning agent, is conducted additionally also through at least one further cavity within the hand-held instrument.

Abstract: A dental hand instrument having an elongate handle sleeve, at the front end of which there are disposed means for holding a treatment tool, for example a dental drill, there are disposed inside the handle sleeve means for driving the treatment tool, which driving means have at least two rotatably mounted shafts that are coupled to each other, a sealing element being disposed in the coupling region of the two shafts inside the handle sleeve.

Abstract: The present invention provides methods for inducing division of postmitotic mammalian differentiated cardiomyocytes. The invention can be used to repair heart tissue damaged by, for example, myocardial ischemia, hypoxia, stroke, myocardial infarction or chronic ischemic heart disease in vivo. In addition, the methods of the invention can be used to induce heart muscle cells to divide in vitro, in vivo and/or ex vivo, which can then be used in heart tissue repair.

Abstract: A motor-driven handpiece, which has a grip sleeve with a head area for mounting a tool, in particular for the preparation of tooth substance and/or bone substance, in which the head area is at least partially surrounded or encapsulated by a thermoplastic material which, compared to the material of the rest of the grip sleeve, has a lower thermal conduction value.

Abstract: In a dental, dental-medical or dental-technical handpiece, having an elongate grip sleeve there are provided at the rearward end of the grip sleeve coupling elements for the connection of the handpiece to a supply hose to be connected with a dental supply arrangement, and there are provided at the forward end of the grip sleeve a head section with a tool receiver for mounting a tool to be put into rotation. The handpiece further has an electric motor for driving a tool held by the tool receiver, which motor is completely integrated into the grip sleeve such that grip sleeve and motor form a unit.

Abstract: In a dental, dental-medical or dental-technical handpiece, having an elongate grip sleeve there are provided at the rearward end of the grip sleeve coupling elements for the connection of the handpiece to a supply hose to be connected with a dental supply arrangement, and there are provided at the forward end of the grip sleeve a head section with a tool receiver for mounting a tool to be put into rotation. The handpiece further has an electric motor for driving a tool held by the tool receiver, which motor is completely integrated into the grip sleeve such that grip sleeve and motor form a unit.

Abstract: A coupling for the production of a releasable connection between a medical, in particular a dental, handpiece part and a supply hose and for the transmission of current and if applicable further supply media from the supply hose to the handpiece part. The coupling includes two coupling elements wherein one of the two coupling elements may be arranged on the supply hose and the other on the handpiece part. A guide element is arranged on one of the two coupling elements, which guide element can be inserted into an insertion opening formed on the other coupling element. In a certain relative rotational position of the two coupling elements a pushing element having current contacts engages into a corresponding recess of the second coupling element, wherein with inserted or at least partly inserted guide element the two coupling elements can be rotated relative to one another around an axis of rotation before attainment of the predetermined coupling position.