Abstract: Pharmaceutical formulations (nanococktails) include two or more nanoparticulate delivery vehicles each including an active agent. The nanococktails can be formulated at any ratio of active agents by changing the ratio of nanoparticulate delivery vehicles in the nanococktail. The nanoparticulate delivery vehicles can have matched surface potential to prevent aggregation. The nanoparticulate delivery vehicles of the combined formulation are designed to provide each active agent with desired, preferably overlapping therapeutic windows and a specifically selected pharmacokinetic and pharmacodynamic profile when the nanococktail is administered to a subject. Each of the nanoparticulate delivery vehicles can be designed to enhance solubility, duration of action, targeting, stability, and to program release while preventing degradation of an active agent and preventing side effects, toxicity, and tolerability issues in a subject.

Abstract: Techniques for a distributed data processing application service in a cloud provider network are described. A virtual machine bundle is obtained, the virtual machine bundle including a copy of a memory and one or more registers of a paused virtual machine executing a distributed data processing application runtime. A request to launch a virtual machine to execute a distributed data processing application runtime is received, the request to launch the virtual machine including a bundle identifier that identifies the virtual machine bundle. The virtual machine is launched based at least in part on the virtual machine bundle. The virtual machine sends a message to register the virtual machine with a cluster of virtual machines.

Abstract: The invention relates to a method and system that implements a peer-to-peer transaction using a QR Code. The invention may be realized by a mobile device that comprises: a memory component that stores customer data; and a computer processor, coupled to the memory, programmed to: send a request for a QR Code for a transaction, wherein the request comprises an amount and a time period; responsive to the request, receive the QR Code on the mobile device; present the QR Code to a payer for the transaction; and receive a payment based on the QR Code, from the payer, where the payment is received in an account associated with the QR Code.

Abstract: Pharmaceutical formulations (nanococktails) include two or more nanoparticulate delivery vehicles each including an active agent. The nanococktails can be formulated at any ratio of active agents by changing the ratio of nanoparticulate delivery vehicles in the nanococktail. The nanoparticulate delivery vehicles can have matched surface potential to prevent aggregation. The nanoparticulate delivery vehicles of the combined formulation are designed to provide each active agent with desired, preferably overlapping therapeutic windows and a specifically selected pharmacokinetic and pharmacodynamic profile when the nanococktail is administered to a subject. Each of the nanoparticulate delivery vehicles can be designed to enhance solubility, duration of action, targeting, stability, and to program release while preventing degradation of an active agent and preventing side effects, toxicity, and tolerability issues in a subject.

Abstract: Various methods, apparatuses/systems, and media for implementing an automation suite module (ASM) for automated functional testing are provided. A receiver receives a request for testing an application. A repository stores a plurality of test classes related to the request. A processor accesses the repository; creates a plurality of packages, each package including one or more test classes among the plurality of test classes; causes, in response to receiving the request for testing the application, a graphical user interface (GUI) to display the plurality of packages with their respective test classes; generates, by utilizing the GUI, a plurality of test blocks by receiving selection of one or more test classes from one or more packages among the plurality of packages; generates, by utilizing the GUI, a custom test suite by receiving selection of one or more test blocks from the plurality of test blocks; and executes the test classes based on the custom test suite to test the application.

Abstract: The present invention is directed to wheat plants and triticale plants having increased tolerance to an imidazolinone herbicide. More particularly, the present invention includes wheat plants or triticale plants containing one or more Triticum turgidum IMI nucleic acids. The present invention also includes seeds produced by these wheat plants and triticale plants, and methods of controlling weeds in the vicinity of these wheat plants and triticale plants.

Abstract: Various methods, apparatuses/systems, and media for implementing an automation suite module (ASM) for automated functional testing are provided. A receiver receives a request for testing an application. A repository stores a plurality of test classes related to the request. A processor accesses the repository; creates a plurality of packages, each package including one or more test classes among the plurality of test classes; causes, in response to receiving the request for testing the application, a graphical user interface (GUI) to display the plurality of packages with their respective test classes; generates, by utilizing the GUI, a plurality of test blocks by receiving selection of one or more test classes from one or more packages among the plurality of packages; generates, by utilizing the GUI, a custom test suite by receiving selection of one or more test blocks from the plurality of test blocks; and executes the test classes based on the custom test suite to test the application.

Abstract: The invention relates to a method and system that implements a peer-to-peer transaction using a QR Code. The invention may be realized by a mobile device that comprises: a memory component that stores customer data; and a computer processor, coupled to the memory, programmed to: send a request for a QR Code for a transaction, wherein the request comprises an amount and a time period; responsive to the request, receive the QR Code on the mobile device; present the QR Code to a payer for the transaction; and receive a payment based on the QR Code, from the payer, where the payment is received in an account associated with the QR Code.

Abstract: The present disclosure relates to a thiolated hydroxypropyl methylcellulose phthalate (T-HPMCP) drug delivery vehicle which is pH responsive and is loaded with either a protein drug or an antigen, to T-HPMCP microparticles, and to a production method for an ileum-specific, pH responsive, T-HPMCP drug delivery vehicle, the method including a step of loading a protein drug or an antigen onto the T-HPMCP microparticles. The T-HPMCP microparticles of the present disclosure are soluble in chlorinated methane because of the introduction of the thiol group, while a T-HPMCP drug delivery vehicle produced from the particles can efficiently effect in vivo delivery of the protein drug or antigen which is loaded thereon, since said vehicle is pH responsive such that the in vivo residence time is extended and the vehicle can act specifically on the ileum.

Abstract: The present invention is directed to wheat plants and triticale plants having increased tolerance to an imidazolinone herbicide. More particularly, the present invention includes wheat plants or triticale plants containing one or more Triticum turgidum IMI nucleic acids. The present invention also includes seeds produced by these wheat plants and triticale plants, and methods of controlling weeds in the vicinity of these wheat plants and triticale plants.

Abstract: The present invention is directed to wheat plants and triticale plants having increased tolerance to an imidazolinone herbicide. More particularly, the present invention includes wheat plants or triticale plants containing one or more Triticum turgidum IMI nucleic acids. The present invention also includes seeds produced by these wheat plants and triticale plants, and methods of controlling weeds in the vicinity of these wheat plants and triticale plants.

Abstract: The present invention is directed to nucleic acids encoding polypeptides that confer upon a plant tolerance to an imidazolinone and/or other acetohydroxyacid synthase (AHAS) inhibiting herbicide when expressed in the plant. The present invention also provides plants having increased tolerance to an imidazolinone and/or other AHAS-inhibiting herbicide. More particularly, the present invention includes plants containing at least one IMI nucleic acid. The present invention also includes seeds produced by these plants and methods of controlling weeds in the vicinity of these wheat plants.

Abstract: The invention provides nucleic acids encoding mutants of the acetohydroxyacid synthase (AHAS) large subunit comprising at least two mutations, for example double and triple mutants, which are useful for producing transgenic or non-transgenic plants with improved levels of tolerance to AHAS-inhibiting herbicides. The invention also provides expression vectors, cells, plants comprising the polynucleotides encoding the AHAS large subunit double and triple mutants, plants comprising two or more AHAS large subunit single mutant polypeptides, and methods for making and using the same.

Abstract: Representative embodiments of a distributed processing method of facilitating interactive analytics of streaming data records by receiving the data records at a plurality of distributed computational nodes, establishing and storing dimensions corresponding to attributes of the data records, parsing the streaming data records to identify matches to at least one of the dimensions and based thereon, reducing the number of data records to create a targeted subset of the data, re-distributing the targeted subsets of the streaming data records among the distributed computational nodes in accordance with the dimensions stored on the nodes, updating a database storing measures of the dimensions in accordance with the targeted subsets of the streaming data records, and using the database to respond to a query based on measures associated with one or more of the dimensions.

Abstract: Representative embodiments of a distributed processing method of facilitating interactive analytics of streaming data records by receiving the data records at a plurality of distributed computational nodes, establishing and storing dimensions corresponding to attributes of the data records, parsing the streaming data records to identify matches to at least one of the dimensions and based thereon, reducing the number of data records to create a targeted subset of the data, re-distributing the targeted subsets of the streaming data records among the distributed computational nodes in accordance with the dimensions stored on the nodes, updating a database storing measures of the dimensions in accordance with the targeted subsets of the streaming data records, and using the database to respond to a query based on measures associated with one or more of the dimensions.

Abstract: Representative embodiments of a distributed processing method of facilitating interactive analytics of streaming data records by receiving the data records at a plurality of distributed computational nodes, establishing and storing dimensions corresponding to attributes of the data records, parsing the streaming data records to identify matches to at least one of the dimensions and based thereon, reducing the number of data records to create a targeted subset of the data, re-distributing the targeted subsets of the streaming data records among the distributed computational nodes in accordance with the dimensions stored on the nodes, updating a database storing measures of the dimensions in accordance with the targeted subsets of the streaming data records, and using the database to respond to a query based on measures associated with one or more of the dimensions.

Abstract: Representative embodiments of a distributed processing method of facilitating interactive analytics of streaming data records by receiving the data records at a plurality of distributed computational nodes, establishing and storing dimensions corresponding to attributes of the data records, parsing the streaming data records to identify matches to at least one of the dimensions and based thereon, reducing the number of data records to create a targeted subset of the data, re-distributing the targeted subsets of the streaming data records among the distributed computational nodes in accordance with the dimensions stored on the nodes, updating a database storing measures of the dimensions in accordance with the targeted subsets of the streaming data records, and using the database to respond to a query based on measures associated with one or more of the dimensions.

Abstract: The present invention is directed to plants having increased tolerance to an imidazolinone herbicide. More particularly, the present invention includes rice plants containing at least one variant AHAS nucleic acid such as an imidazolinone tolerant IMINTA 1, 4 or 5 lines comprising an alanine to threonine substitution as compared to the wild-type AHAS. The present invention also includes seeds produced by these rice plants and methods of controlling weeds in the vicinity of these rice plants.

Abstract: The invention provides transgenic or non-transgenic plants with improved levels of tolerance to AHAS-inhibiting herbicides. The invention also provides nucleic acids encoding mutants of the acetohydroxyacid synthase (AHAS) large subunit, expression vectors, plants comprising the nucleic acids encoding the AHASL subunits containing one, two, or more mutations, plants comprising such AHASL subunit mutant nucleic acids, methods for making and using the same, and methods of controlling weeds.

Abstract: The present invention relates to improved methods for the incorporation of DNA into the genome of a Zea mays plant by means of Agrobacterium-mediated transformation. Preferred is the use of the Zea may lines deposited with American Type Culture Collection under the Patent Deposit Designation PTA-6170 and PTA-6171.