Abstract: An apparatus for cultivation of cells, particularly podocytes, is described. The apparatus includes a cell cultivation surface exhibiting at least one feature providing a non-planar microtopology. A method for cultivation of cells, particularly podocytes, is also described. The method includes introducing a differentiation media including ATRA, Vit D3, and Dex.

Abstract: A backside-illuminated color image sensor with crosstalk-suppressing color filter array includes (a) a silicon layer including an array of photodiodes and (b) a color filter layer on the light-receiving surface of the silicon layer, wherein the color filter layer includes (i) an array of color filters cooperating with the array of photodiodes to form a respective array of color pixels and (ii) a light barrier grid disposed between the color filters to suppress transmission of light between adjacent ones of the color filters.

Abstract: A phase-detection auto-focus (PDAF) pixel array includes a first pixel and a second pixel. The first pixel, located at a first distance from a center of the PDAF pixel array, includes a first inner photodiode and a first outer photodiode with respect to the center. The first inner photodiode and the first outer photodiode occupy respectively a first inner area and a first outer area. The first inner area divided by the first outer area equals a first ratio. The second pixel, located at a second distance from the center that exceeds the first distance, includes a second inner photodiode and a second outer photodiode with respect to the center. The second inner photodiode and the second outer photodiode occupy respectively a second inner area and a second outer area. The second inner area divided by the second outer area equals a second ratio, which exceeds the first ratio.

Abstract: The present description relates to the discovery of materials, devices, systems and methods for microfabrication of engineered tissue scaffolds for the growth and culture of biological tissues for tissue repair, transplantation, disease treatment, regenerative medicine, drug testing or combinations thereof. The engineered tissue scaffolds mimic native conditions and structures, including, e.g., native physiology, tissue architecture, vasculature, and other properties of native tissues.

Abstract: A phase-detection auto-focus (PDAF) pixel array includes a first pixel and a second pixel. The first pixel, located at a first distance from a center of the PDAF pixel array, includes a first inner photodiode and a first outer photodiode with respect to the center. The first inner photodiode and the first outer photodiode occupy respectively a first inner area and a first outer area. The first inner area divided by the first outer area equals a first ratio. The second pixel, located at a second distance from the center that exceeds the first distance, includes a second inner photodiode and a second outer photodiode with respect to the center. The second inner photodiode and the second outer photodiode occupy respectively a second inner area and a second outer area. The second inner area divided by the second outer area equals a second ratio, which exceeds the first ratio.

Abstract: Methods and devices are disclosed for providing the controlled formation of planar homogeneous or heterogeneous materials using microfluidic devices. In one embodiment, a planar array of microfluidic channels is employed to produce a flowing liquid sheet having heterogeneous structure by spatially and temporally controlling dispensing of polymer liquid from selected microchannels. The resulting liquid sheet is solidified to produce a planar heterogeneous material that may be continuously drawn and/or fed from the plurality of microfluidic channels. The polymer liquid may include a payload that may be selectively incorporated into the heterogeneous structure. In some embodiments, the local material composition is controllable, thereby allowing control over local and bulk material properties, such as the permeability and the elasticity, and of creating materials with directionally dependent properties.

Abstract: A first plasmonic-nanostructure sensor pixel includes a semiconductor substrate and a plurality of metal pillars. The semiconductor substrate has a top surface and a photodiode region therebeneath. The plurality of metal pillars is at least partially embedded in the substrate and extends from the top surface in a direction substantially perpendicular to the top surface. A second plasmonic-nanostructure sensor pixel includes (a) a semiconductor substrate having a top surface, (b) an oxide layer on the top surface, (c) a thin-film coating between the top surface and the oxide layer, and (d) a plurality of metal nanoparticles (i) at least partially between the top surface and the oxide layer and (ii) at least partially embedded in at least one of the thin-film coating and the oxide layer. A third plasmonic-nanostructure sensor pixel includes features of both the first and second plasmonic-nanostructure sensor pixels.

Abstract: The present disclosure provides methods, compositions, and devices for making and using three-dimensional biological tissues that accurately mimic native physiology, architecture, and other properties of native tissues for use in, among other applications, drug testing, tissue repair and/or treatment, and regenerative medicine.

Abstract: A system and method for synchronizing the phases and frequencies of devices in multi-user, wireless communications systems are provided. A primary beacon signal is transmitted by a destination node in a wireless communications network to a plurality of source nodes. Secondary beacon signals are also exchanged between the source nodes. Using the primary and secondary beacon signals, the nodes generate local phase and frequency estimates which are used to control local phases and frequencies of the source nodes. The source nodes then transmit common information to the destination at carrier frequencies based on the estimated local frequencies and phases, so that the phases and frequencies of the transmitted information are synchronized to facilitate coherent combining of the bandpass signals at the destination. Phase and frequency synchronization can be applied to wireless communications systems having any number of source nodes, and effects of Doppler shifts and moving platforms are accounted for.

Abstract: Methods and devices are disclosed for providing the controlled formation of planar homogeneous or heterogeneous materials using microfluidic devices. In one embodiment, a planar array of microfluidic channels is employed to produce a flowing liquid sheet having heterogeneous structure by spatially and temporally controlling dispensing of polymer liquid from selected microchannels. The resulting liquid sheet is solidified to produce a planar heterogeneous material that may be continuously drawn and/or fed from the plurality of microfluidic channels. The polymer liquid may include a payload that may be selectively incorporated into the heterogeneous structure. In some embodiments, the local material composition is controllable, thereby allowing control over local and bulk material properties, such as the permeability and the elasticity, and of creating materials with directionally dependent properties.

Abstract: A system and method for synchronizing the phases and frequencies of devices in multi-user, wireless communications systems are provided. A primary beacon signal is transmitted by a destination node in a wireless communications network to a plurality of source nodes. Secondary beacon signals are also exchanged between the source nodes. Using the primary and secondary beacon signals, the nodes generate local phase and frequency estimates which are used to control local phases and frequencies of the source nodes. The source nodes then transmit common information to the destination at carrier frequencies based on the estimated local frequencies and phases, so that the phases and frequencies of the transmitted information are synchronized to facilitate coherent combining of the bandpass signals at the destination. Phase and frequency synchronization can be applied to wireless communications systems having any number of source nodes, and effects of Doppler shifts and moving platforms are accounted for.

Abstract: A system and method for synchronizing the phases and frequencies of devices in multi-user, wireless communications systems are provided. A primary beacon signal is transmitted by a destination node in a wireless communications network to a plurality of source nodes. Secondary beacon signals are also exchanged between the source nodes. Using the primary and secondary beacon signals, the nodes generate local phase and frequency estimates which are used to control local phases and frequencies of the source nodes. The source nodes then transmit common information to the destination at carrier frequencies based on the estimated local frequencies and phases, so that the phases and frequencies of the transmitted information are synchronized to facilitate coherent combining of the bandpass signals at the destination. Phase and frequency synchronization can be applied to wireless communications systems having any number of source nodes, and effects of Doppler shifts and moving platforms are accounted for.

Abstract: A system and method for synchronizing the phases and frequencies of devices in multi-user, wireless communications systems are provided. A primary beacon signal is transmitted by a destination node in a wireless communications network to a plurality of source nodes. Secondary beacon signals are also exchanged between the source nodes. Using the primary and secondary beacon signals, the nodes generate local phase and frequency estimates which are used to control local phases and frequencies of the source nodes. The source nodes then transmit common information to the destination at carrier frequencies based on the estimated local frequencies and phases, so that the phases and frequencies of the transmitted information are synchronized to facilitate coherent combining of the bandpass signals at the destination. Phase and frequency synchronization can be applied to wireless communications systems having any number of source nodes, and effects of Doppler shifts and moving platforms are accounted for.