Abstract: Methods for calibrating neuromuscular signals sensed by a plurality of neuromuscular-signal sensors are provided. One example method includes, in response to a triggering event, receiving a pulse sensed by a neuromuscular-signal sensor of a plurality of neuromuscular-signal sensors of a wrist-wearable device. The method also includes, in accordance with a determination that the pulse indicates that at least one neuromuscular-signal sensor of the plurality of neuromuscular-signal sensors of the wrist-wearable device is offset from a respective predetermined default position, determining a worn position of the wrist-wearable device on the user's wrist, and adjusting analysis of neuromuscular signals of the plurality of neuromuscular-signal sensors based on an offset between the worn position of the wrist-wearable device and a predetermined default position of the wrist-wearable device.

Abstract: A plunger head for a fluid injection device includes a transducer disposed in the plunger head to measure a compressive force when applied to the plunger head. The plunger head also includes a power source and a microcontroller disposed in the plunger head. The microcontroller is coupled to the power source and the transducer, and the microcontroller is coupled to enter a high-power mode in response to sensing application of the compressive force to the plunger head.

Abstract: Systems and devices for tracking the opening and closing of a container are provided. According to an aspect of the invention, a device includes a body that is configured to be inserted between a container and a cap that is configured to seal the container, a sensor that is configured to measure a state of the cap as being opened or closed, a microprocessor that is configured to receive a signal from the sensor that represents the state of the cap, and a transmitter that is configured to send a message that indicates the state of the cap.

Abstract: Techniques are disclosed for gating state transitions of a medically related device. Specifically, detection that a particular condition is satisfied can directly or indirectly trigger switching the medically related device from operating in a normal operation mode to a suppressed operation mode.

Abstract: Devices are provided to automatically access blood from beneath or within skin. These devices include a plurality of injectors configured to drive needles into the skin and draw samples of blood into the device. These devices additionally include a plurality of sensors which can detect a target analyte in the blood samples received by the device. These devices further include a user interface, which may prompt the user to self-administer a dose of a substance, or accept a user input which could affect or otherwise influence the activation of the device (i.e., the firing of needles to draw blood samples into the device and detect an analyte). These devices can be wearable and configured to automatically access blood from skin, for example, to access blood from the skin at one or more points in time after the user has self-administered a dose of a substance.

Abstract: A plunger head for a fluid injection device includes a transducer disposed in the plunger head to measure a compressive force when applied to the plunger head. The plunger head also includes a power source and a microcontroller disposed in the plunger head. The microcontroller is coupled to the power source and the transducer, and the microcontroller is coupled to enter a high-power mode in response to sensing application of the compressive force to the plunger head.

Abstract: A medication injection device including a plunger, a temperature sensor, an antenna, and a controller is described herein. The plunger is configured to dispense medication. The temperature sensor is to measure a temperature representative of an ambient temperature of the medication injection device. The antenna is to pair the medication injection device with a remote device. The controller includes logic that when executed causes the medication injection device to perform operations, including placing the medication injection device into a low-power sleep mode, measuring the temperature with the temperature sensor at a regular interval while the medication injection in the low-power sleep mode, detecting a temperature change with the temperature sensor while in the low-power sleep mode, transitioning the medication injection device into an initialization mode in response, and pairing the medication injection device with the remote device using the antenna while in the initialization mode.

Abstract: A plunger head for a medication injection device includes a first ultrasonic transducer coupled to emit ultrasonic signals, where the first ultrasonic transducer is oriented within the plunger head to send the ultrasonic signals along a length of a barrel of the medication injection device when the plunger head is disposed in the barrel. A second ultrasonic transducer is disposed within the plunger head and oriented to receive reflections of the ultrasonic signals. A controller is disposed in the plunger head and coupled to the first ultrasonic transducer and the second ultrasonic transducer. The controller includes logic that when executed by the controller causes the controller to perform operations including instructing the first ultrasonic transducer to emit the ultrasonic signals.

Abstract: The present disclosure relates to a stopper adapted for use in a drug delivery device. In one implementation, the stopper includes a rigid casing having a shape adapted to fit within a barrel of the drug delivery device; electronics disposed and sealed within the rigid casing; and an elastomeric seal disposed around at least a dispensing end of the rigid casing and a side of the rigid casing. The electronics include a power source and at least one of a transducer or a sensor coupled to the power source. The elastomeric seal comprises a single continuous material.

Abstract: In some examples, a fluid delivery device is described. The fluid deliver device includes a housing; a reservoir disposed within the housing, the fluid reservoir defining a fluid outlet at a first end of the fluid reservoir; a plunger assembly disposed within the fluid reservoir, the plunger assembly including a friction clutch; and a seal engaged with an interior surface of the fluid reservoir to prevent movement of a material within the fluid reservoir past the seal; and a motive element in communication with a first end of the plunger assembly and configured to apply a motive force on the first end of the plunger assembly towards the first end of the fluid reservoir, wherein the friction clutch is configured to apply a frictional force to the interior surface of the fluid reservoir to resist the motive force, and wherein operation of the friction clutch enables motive force to overcome the frictional force to allow the plunger assembly to translate towards the first end of the fluid reservoir.

Abstract: A plunger head for a fluid injection device includes a transducer disposed in the plunger head to measure a compressive force when applied to the plunger head. The plunger head also includes a power source and a microcontroller disposed in the plunger head. The microcontroller is coupled to the power source and the transducer, and the microcontroller is coupled to enter a high-power mode in response to sensing application of the compressive force to the plunger head.

Abstract: The present disclosure relates to a rigid sensor stopper adapted for use in a drug delivery device. In one implementation, a rigid sensor stopper may include a transducer, a power source, a rigid molding or casing, and at least one elastomeric seal. The molding may be formed from overmolding or insert molding, and the casing may be formed from injection molding, machining, or forged casing. The at least one elastomeric seal may include at least two o-rings.

Abstract: A device may include a housing, a light-permeable electrode, a computing device, and a display or other light-processing element. The display or other light-processing element may be positioned at least partly within the housing. The device components may be arranged to permit passage of light through the light-permeable electrode and relative to the light-processing element. The computing device may utilize electrical activity signal information from the light-permeable electrode to determine electrocardiogram (ECG) information or other information about the body of a user of the device. For example, the computing device may cause such ECG information to be projected through the light-permeable electrode by the display or other light-processing device and/or obtain additional information based on light received through the light-permeable electrode by the display or other light-processing device.

Abstract: A drug cartridge to dispense an injectable fluid includes a drug cartridge body with an interior cavity, a neck region, and a bottom region. The neck region is opposite the bottom region and the interior cavity of the drug cartridge narrows in the neck region and is wider than most of the neck region in the bottom region. A transducer is coupled to emit sonic waves into the interior cavity towards the neck region, and the neck region is geometrically oriented to reflect the sonic waves back from the neck region towards the bottom region to be received by the transducer.

Abstract: A method of manufacturing a plunger head for a medication injection device includes assembling at least a portion of a first component, assembling at least a portion of a second component, and assembling the first component into a cavity of the second component. The first component has a distal end and a proximal end, the distal end being configured for insertion into a barrel of the medication injection device before the proximal end, and the first component houses at least one electronic component. The second component is configured to at least partially surround the first component and to separate the first component from a medication contained within the barrel of the medication injection device.

Abstract: Various apparatuses and methods for tracking the administration of medication by medication injection devices are provided. A plunger head for a medication injection device may include a first component that houses electronic components and a second component that couples to the first component to form the plunger head. When the plunger head is installed within a barrel of the medication injection device the second component may separate the first component from medication contained within the barrel.

Abstract: A plunger head for a medication injection device includes a first ultrasonic transducer coupled to emit ultrasonic signals, where the first ultrasonic transducer is oriented within the plunger head to send the ultrasonic signals along a length of a barrel of the medication injection device when the plunger head is disposed in the barrel. A second ultrasonic transducer is disposed within the plunger head and oriented to receive reflections of the ultrasonic signals. A controller is disposed in the plunger head and coupled to the first ultrasonic transducer and the second ultrasonic transducer. The controller includes logic that when executed by the controller causes the controller to perform operations including instructing the first ultrasonic transducer to emit the ultrasonic signals.

Abstract: An apparatus includes a pen body of a drug injection pen including a dosage injection mechanism that produces a rotational motion when the drug injection pen dispenses a fluid. The apparatus also includes a button housing with at least part of a dosage measurement system disposed within the button housing. At least part of the dosage measurement system is coupled to receive the rotational motion from the dosage injection mechanism. The dosage measurement system includes one or more sensors positioned to output a signal in response to the rotational motion when the drug injection pen dispenses a fluid, and a controller coupled to the one or more sensors to receive the signal. A drug delivery control wheel of the drug injection pen is disposed between the body of the drug injection pen and the at least part of the dosage measurement system disposed in the button housing.

Abstract: A drug injection pen includes a housing shaped to accept a cartridge containing a fluid, and a dosage injection mechanism positioned in the housing to produce a rotational motion and force the fluid out of the cartridge when the drug injection pen dispenses the fluid. A dosage measurement system is disposed in the drug injection pen and is coupled to measure a strain induced in a portion of the dosage measurement system. The dosage measurement system outputs a signal indicative of the strain, and the strain on the portion of the dosage measurement system changes when the dosage injection mechanism dispenses the fluid. The dosage measurement system outputs a signal indicative of the strain when the drug injection pen dispenses the fluid. A controller is coupled to the dosage measurement system, and the controller performs operations including recording the signal output from the dosage measurement system.

Abstract: A drug cartridge to dispense an injectable fluid includes a drug cartridge body with an interior cavity, a neck region, and a bottom region. The neck region is opposite the bottom region and the interior cavity of the drug cartridge narrows in the neck region and is wider than most of the neck region in the bottom region. A transducer is coupled to emit sonic waves into the interior cavity towards the neck region, and the neck region is geometrically oriented to reflect the sonic waves back from the neck region towards the bottom region to be received by the transducer.