Abstract: An example device includes a silicon substrate having a first substrate surface and a second substrate surface; a plurality of layers associated with one or more electronic components of an integrated circuit (IC), where the plurality of layers are deposited on the second substrate surface; a lithium-based battery having a plurality of battery layers deposited on the first substrate surface of the silicon substrate, where the lithium-based battery includes an anode current collector and a cathode current collector; a first through-silicon via (TSV) passing through the silicon substrate and providing an electrical connection between the anode current collector and the plurality of layers associated with the one or more electronic components of the IC; and a second TSV passing through the silicon substrate and providing an electrical connection between the cathode current collector and the plurality of layers associated with the one or more electronic components of the IC.

Abstract: Apparatus, systems and methods of contact lenses with power sources are provided. In some aspects, a contact lens can include a substrate; and a circuit. The circuit can include: one or more sensors disposed on or within the substrate; circuitry disposed on at least a portion of the substrate; one or more photovoltaic cells disposed on at least a portion of the substrate; and a hybrid power component that supplies at least one of two or more different types of power to the circuitry, wherein at least one of the two or more different types of power is radio frequency/inductive power. In various aspects, other types of power can be solar and/or microelectromechanical system power. Additionally, in various aspects, photovoltaic cells can be arrayed in different configurations and/or over a significant portion of a viewing surface of the contact lens. In some aspects, the photovoltaic cells can be transparent.

Abstract: In one aspect of the present disclosure, a method is disclosed. The method involves: a reader detecting an eye-mountable device within a wireless communication range of the reader, wherein the eye-mountable device includes a transparent material having a concave mounting surface configured to be removably mounted on a corneal surface; wirelessly retrieving from the detected eye-mountable device a first set of data; using the retrieved first set of data to determine that a condition has been satisfied; and responsive to using the retrieved first set of data to determine that the condition has been satisfied, retrieving from the detected eye-mountable device a second set of data.

Abstract: A body-mountable device includes a flexible substrate configured for mounting to a skin surface. The flexible substrate is configured to be adhered or otherwise mounted to the skin in a manner that minimally impacts activities of the body. The device includes a flexible display configured to provide indications to a user, e.g., indications of sensor readings, medical alerts, or operational states of the device. The display could be operated on a very low power budget, e.g., the display could be operated intermittently. In some examples, the display could include an e-paper display or similar low power display elements. In some examples, elements of the display, e.g., electrodes of a multi-segment display, could be formed on the flexible substrate such that additional elements of the display, e.g., a layer of display medium and a layer of transparent conductor, could be adhered or otherwise attached to the formed elements.

Abstract: The present disclosure provides methods and apparatuses for providing an audible feedback based on a proximity or a link quality between an external reader and a tag. The external reader transmits power to the tag with a radio frequency electromagnetic signal. The tag may rectify the radio frequency electromagnetic signal and create a rectified voltage. This rectified voltage may be used to power various components of the tag. Once it receives power from the reader, the tag may communicate information back to the external reader. The information communicated back to the reader is communicated by modulating an antenna impedance of the tag. By modulating the impedance, the tag will backscatter radiation transmitted by the reader. The reader is able to create an audio output based on determining the proximity or link quality from the reader to the tag based on the backscatter radiation it receives from the tag.

Abstract: A reader for communicating with both an eye-mountable device and a display device is provided. The reader can transmit radio frequency power to a tag that is part of the eye-mountable device. The reader can communicates with the tag using a first protocol. Communicating with the tag can include having the reader request data from the tag and receive the requested data from the tag. The reader can process the received data. The reader can store the processed data. The reader can communicates with the display device using a second protocol, where the first and second protocols can differ. Communicating with the display device can include having the reader transmit the stored data to the display device. The display device can receive the transmitted data, process the transmitted data, and generate one or more displays including the transmitted and/or processed data.

Abstract: A flexible, body-mountable analyte sensing device includes a flexible substrate configured for mounting to skin of a living body. The sensing device additionally includes a sensor probe attached to the flexible substrate and configured to penetrate the skin such that a sensor disposed on the end of the sensor probe can be exposed to an analyte in interstitial fluid. The sensor could be an electrochemical sensor that includes two or more electrodes disposed at the end of the sensor probe and configured to electrochemically detect the analyte. The sensing device is configured to display detected concentrations or other information about the analyte in the interstitial fluid. The flexible substrate of the sensing device is configured to be adhered or otherwise mounted to the skin in a manner that minimally impacts activities of the living body.

Abstract: Systems and methods are described that relate to a plurality of sensors configured to measure a physiological parameter. Each sensor of the plurality of sensors may be removably attached to an exterior surface of a living body. A controller may be configured to receive sensor data from the plurality of sensors. The sensor data may be indicative of the physiological parameter. The controller may correlate the sensor data to provide correlated data that is indicative of the physiological parameter. Based at least on the correlated data, the controller may determine a health state. The controller may further provide an indication based on the determined health state.

Abstract: Apparatus, systems and methods of contact lenses with power sources are provided. In some aspects, a contact lens can include a substrate; and a circuit. The circuit can include: one or more sensors disposed on or within the substrate; circuitry disposed on at least a portion of the substrate; one or more photovoltaic cells disposed on at least a portion of the substrate; and a hybrid power component that supplies at least one of two or more different types of power to the circuitry, wherein at least one of the two or more different types of power is radio frequency/inductive power. In various aspects, other types of power can be solar and/or microelectromechanical system power. Additionally, in various aspects, photovoltaic cells can be arrayed in different configurations and/or over a significant portion of a viewing surface of the contact lens. In some aspects, the photovoltaic cells can be transparent.

Abstract: A flexible, body-mountable analyte sensing device includes a flexible substrate configured for mounting to skin of a living body. The sensing device additionally includes optical fiber attached to the flexible substrate and configured to penetrate the skin such that an analyte-sensitive substance disposed on the end of the optical fiber can detect an analyte in interstitial fluid. A color, fluorescence intensity, or other optical property of the analyte-sensitive substance is related to the concentration or other property of the analyte. Light reflected, scattered, fluorescently emitted, or otherwise emitted from the analyte-sensitive substance is transmitted via the optical fiber and detected by a light sensor on the flexible substrate. Such emitted light can be emitted in response to illumination of the analyte-sensitive substance via the optical fiber. The sensing device is configured to wirelessly indicate detected concentrations or other information about the analyte in the interstitial fluid.

Abstract: An eye-mountable device includes an enclosure material, a sensor system, and a controller. The enclosure material has a first surface and a second surface. The first surface is configured to be removeably mounted over a cornea and the second surface is configured to be compatible with eyelid motion when the concave surface is so mounted. The sensor system is disposed within the enclosure material. The sensor system has at least one value that varies with changes in a gazing direction of the cornea. The controller is disposed within the enclosure material and electrically connected to the sensor system. The controller is configured to measure the value of the sensor system to detect the changes in the gazing direction.

Abstract: Systems and methods for the wireless transfer of power between two hermetically sealed devices are described herein. An example system may include a battery package and a hermetically sealed body-implantable electronic device having an electronics package. The battery package may include one or more alignment structures, configured to removably align the battery package with the electronic device, a battery, and a wireless power transceiver. At least the battery and the wireless power transceiver of the battery package may be contained within a hermetic material separate from the electronic device. Power may be wirelessly transferred between the devices by any means, including inductive coupling or capacitive coupling. In some examples, the hermetically-sealed devices may be implanted in a living body.

Abstract: A body-mountable device includes a flexible substrate configured for mounting to a skin surface. The device includes an input component configured to receive inputs from a user, e.g., finger presses, swipes, motions of the sensing platform, or gestures. Received inputs could include calibration data, for example, known values of a sensed property to compare with corresponding values obtained by a sensor of the device. The device can additionally include an output component configured to provide outputs to a user. Outputs could include indications of sensor readings, medical alerts, or operational states of the device. The flexible substrate of the device is configured to be adhered or otherwise mounted to the skin in a manner that minimally impacts activities of the body.

Abstract: A method of capacitive gaze detection for accommodation includes monitoring at least one capacitance value of a capacitive sensor system disposed within a contact lens. The at least one capacitance value varies in response to changes in a gazing direction of a cornea upon which the contact lens is removeably mounted. The changes in the gazing direction of the cornea are detected in real-time based upon changes in the at least one capacitance value. An accommodation actuator disposed within the contact lens is manipulated to automatically change an optical power of the contact lens in response to detecting changes in the gazing direction.

Abstract: An eye-mountable device includes an enclosure material, a capacitive sensor system, and a controller. The enclosure material has a concave surface and a convex surface. The concave surface is configured to be removeably mounted over a cornea and the convex surface is configured to be compatible with eyelid motion when the concave surface is so mounted. The capacitive sensor system is disposed within the enclosure material. The capacitive sensor system has at least one capacitance value that varies with changes in a gazing direction of the cornea. The controller is disposed within the enclosure material and electrically connected to the capacitive sensor system. The controller is configured to measure the capacitance value of the capacitive sensor system to detect the changes in the gazing direction.

Abstract: An electrochemical sensor of a flexible, body-mountable analyte sensing device is provided. The electrochemical sensor is disposed on a flexible sensor probe that is configured to penetrate the skin such that the electrochemical sensor disposed on the sensor probe can detect an analyte in interstitial fluid. The electrochemical sensor is made sensitive to the analyte by disposing a substance that selectively binds to reacts with, catalyzes a reaction of, or otherwise selectively interacts with the analyte. The substance is localized by crosslinking on the surface of an electrode and/or by being disposed in a polymer layer disposed on the electrode. The polymer layer can be a hydrogel. Further, a hydrogel layer can be formed on the sensor probe to protect elements of the sensor probe and to increase the biocompatibility of the sensor probe.

Abstract: A flexible, body-mountable analyte sensing device includes a flexible substrate configured for mounting to skin of a living body. The sensing device additionally includes a sensor probe attached to the flexible substrate and configured to penetrate the skin such that a sensor disposed on the sensor probe can detect an analyte in interstitial fluid. The sensor probe can include an elongate extension of the flexible substrate. The sensor can be, for example, an electrochemical sensor or an optical sensor. The sensing device is configured to wirelessly indicate detected concentrations or other information about the analyte in the interstitial fluid. The flexible substrate of the sensing device is configured to be adhered or otherwise mounted to the skin in a manner that minimally impacts activities of the living body.

Abstract: This disclosure relates to systems and/or methods for subtracting in the current domain an output current primary signal from a primary sensor from an output current reference signal from a reference sensor to produce a frequency output signal indicative of the difference between the output current primary signal and the output current reference signal.

Abstract: A potentiostat includes a voltage regulator, a current mirror, a capacitor, a comparator, a current source, and a counter. The voltage regulator maintains a voltage on a working electrode of an electrochemical sensor. The current mirror develops a mirror current that mirrors an input current from the working electrode. The capacitor is alternately charged by the mirror current, causing the capacitor voltage to increase at a rate related to the current's magnitude, and discharged by a control current, causing the capacitor voltage to decrease. The comparator outputs a waveform that includes upward and downward transitions based on the variations of the capacitor voltage. The current source produces the control current based on the waveform. The counter counts the number of upward or downward transitions in the waveform during a predetermined sampling period to produce a digital output. The digital output is representative of the magnitude of the input current.

Abstract: Apparatus and methods employing contact lenses having electrochemical sensors that have adjustable analyte-sensing sensitivity are provided. In some aspects, level of the analyte or biological substance is detected and a number of sub-electrodes of the sensor are turned on or off based on the level of the analyte or biological substance. The sensitivity of the sensor is adjusted based on the number of sub-electrodes that are turned on or off. In some aspects, the current level from the sensor is employed in determining the number of sub-electrodes to turn on or off. In one aspect, a contact lens includes: a substrate; a power component; a circuit and an adjustment circuit. The circuit can include a potentiostat; and a sensor electrically coupled to the potentiostat, and configured to sense a level of an analyte. The sensitivity of the sensor can be adjustable by the adjustment circuit.