Abstract: Techniques for secure and efficient interfacing with a cloud computing service are described. In an embodiment, a cloud computing management service is programmed or configured to communicate with a cloud computing service. The cloud computing management service can be accessed by software engineers that are looking to deploy a software instance to a computing device of the cloud computing service. Thus, the cloud computing management service acts as an intermediary layer in front of the cloud computing service. In an embodiment, the cloud computing management service may store one or more frequently-used system parameters for deployment of software instances. The parameters conform to company's security protocols, compliance protocols, and/or other standards.

Abstract: A glass fencing system includes glass panels, rails, gaskets, and spigots. The rails extend across the upper edges of the glass panels. The gaskets are fitted within the rails. The spigots support one of the glass panels and comprise a base, a first arm, a first pad, a second arm, and a second pad. The first pad has a first pad surface and a lower surface. The first pad surface is in contact with the first arm and the glass panel. The lower surface extends from the first pad surface and is in contact with the glass panels. The second arm has bores. The second pad has a second pad surface, a backing, a plate, and fasteners. The second pad surface is in contact with the glass panel. The backing is spaced apart from the second pad surface and has backing openings aligned with the bores. The plate is located between the second pad surface and the backing. The fasteners pass through the bores and the backing openings to contact the plate.

Abstract: A railing system for stairs comprises a plurality of pickets, a first rail, and a second rail. The first rail comprises a handle portion, an attachment portion, and a first cover. The attachment portion is attached to the pickets using fasteners. The first cover is adapted to cover the fasteners when the attachment portion is attached to the pickets. The second rail comprises a base member, a base sidewall, and a second cover. The base member comprises a plurality of base openings adapted to receive the pickets. The base sidewall is attached to the pickets using fasteners. The second cover is adapted to fit over the fasteners when base sidewall is attached to the pickets.

Abstract: A system for controlling an agent interacting with an environment to perform a task. The system includes an action selection neural network configured to generate action selection outputs that are used to select actions to be performed by the agent. The action selection neural network includes an encoder sub network configured to generate encoded representations of the current observations; an attention sub network configured to generate attention sub network outputs with the used of an attention mechanism; a recurrent sub network configured to generate recurrent sub network outputs; and an action selection sub network configured to generate the action selection outputs that are used to select the actions to be performed by the agent in response to the current observations.

Abstract: A compound of formula (I), or a pharmaceutically acceptable salt thereof.

Abstract: The invention provides expression vectors, nucleic acids, vector particles and methods of treatment involving these vector particles, comprising an engineered KCNA1 gene encoding an edited Kv1.1 potassium channel, as well as methods of confirming the presence of engineered KCNA1 mRNA in a cell. The features of the engineered KCNA1 gene combine to advantageously enhance the translation and activity of the Kv1.1 protein and improve detection of KCNA1 gene expression in a cell and can be used for example in the treatment of epilepsy and similar neurological disorders.

Abstract: A sealed, passively pumped, polycrystalline ceramic vacuum chamber and method for fabricating the chamber are disclosed. The body of the vacuum chamber is made from a polycrystalline ceramic, for example, alumina. The vacuum chamber includes one or more windows made from a transparent ceramic, for example, sapphire, to accommodate optical access, while remaining amorphous-glass free to minimize or eliminate helium permeation. The vacuum chamber components are joined via laser welding or furnace brazing and the completed chamber is bakeable at temperatures up to 400° C. The vacuum chamber can operate at high or ultra-high vacuum pressures for an extended period through the use of one or more getter-based pumps. The vacuum chamber may include one or more atomic sources depending upon the application.

Abstract: The invention provides expression vectors or vector systems comprising a polynucleotide sequence encoding a polypeptide, wherein the gene is operably linked to a neuronal activity-dependent promoter suitable to drive expression of the gene product in a subject’s neural cells. The features of the expression vectors combine to advantageously improve the treatment of a neurological disorder associated with neuronal hyperexcitability in a subject. The invention also provides the expression vectors or vector systems for use in related methods of treatment, as well as viral particles, cells, kits and methods using the expression vectors or vector systems.

Abstract: Implant delivery devices, methods of device assembly and methods of using those devices are presented where the delivery device uses an automatic implant delivery mechanism that eliminates variability in pusher wire speeds by providing a needle assembly having one or more implants positioned within a proximal end of a needle cannula, a dampener assembly and a shuttle assembly located within a housing along with the activation member which holds the shuttle assembly in cocked or pre-tensioned state. A lock can be engaged with the activation member to prevent premature firing or triggering of the device.

Abstract: A hermetically-sealed edge-connect header that can withstand high temperatures, high pressures (or high vacuum levels), and high vibration environments, along with two corresponding connectors are disclosed. After brazing the edge-connect header components, the assembly is machined to form a slot with a portion of each of a plurality of electrical conductors removed in the machining process, resulting in a header with a high pin density. During the process of mating the first connector design to the edge-connect header, a plurality of wipers in the connector deflect, thereby causing the wipers to extend from the connector and contact the corresponding electrical conductors in the header. During the process of mating the second connector design to the edge-connect header, each of a plurality of wipers formed of low-mass, compliant metal wool, forms multiple contact points with a corresponding electrical conductor in the header.

Abstract: A hermetically-sealed edge-connect header that can withstand high temperatures, high pressures (or high vacuum levels), and high vibration environments, along with two corresponding connectors are disclosed. After brazing the edge-connect header components, the assembly is machined to form a slot with a portion of each of a plurality of electrical conductors removed in the machining process, resulting in a header with a high pin density. During the process of mating the first connector design to the edge-connect header, a plurality of wipers in the connector deflect, thereby causing the wipers to extend from the connector and contact the corresponding electrical conductors in the header. During the process of mating the second connector design to the edge-connect header, each of a plurality of wipers formed of low-mass, compliant metal wool, forms multiple contact points with a corresponding electrical conductor in the header.

Abstract: Nanometers thick conformal coatings deposited by atomic-layer deposition (ALD) onto the metal surface of an active braze joint modifies the surface chemistry to eliminate excess braze filler metal flow. Unlike other means used to prevent braze filler metal runout, the thin ALD coating does not hinder next assembly processes, does not require post-braze cleaning, and does not alter the base material mechanical properties.

Abstract: Systems and methods detect a multicomponent brain-based bio-signal in non-brain internal body tissues and cavities of a patient, such as the mouth. Sub-component signals are filtered from the multi-component signal to isolate frequency brave wave bands.

Abstract: A hermetically-sealed edge-connect header that can withstand high temperatures, high pressures (or high vacuum levels), and high vibration environments, along with two corresponding connectors are disclosed. After brazing the edge-connect header components, the assembly is machined to form a slot with a portion of each of a plurality of electrical conductors removed in the machining process, resulting in a header with a high pin density. During the process of mating the first connector design to the edge-connect header, a plurality of wipers in the connector deflect, thereby causing the wipers to extend from the connector and contact the corresponding electrical conductors in the header. During the process of mating the second connector design to the edge-connect header, each of a plurality of wipers formed of low-mass, compliant metal wool, forms multiple contact points with a corresponding electrical conductor in the header.

Abstract: A hermetically-sealed edge-connect header that can withstand high temperatures, high pressures (or high vacuum levels), and high vibration environments, along with two corresponding connectors are disclosed. After brazing the edge-connect header components, the assembly is machined to form a slot with a portion of each of a plurality of electrical conductors removed in the machining process, resulting in a header with a high pin density. During the process of mating the first connector design to the edge-connect header, a plurality of wipers in the connector deflect, thereby causing the wipers to extend from the connector and contact the corresponding electrical conductors in the header. During the process of mating the second connector design to the edge-connect header, each of a plurality of wipers formed of low-mass, compliant metal wool, forms multiple contact points with a corresponding electrical conductor in the header.

Abstract: A hermetically-sealed edge-connect header that can withstand high temperatures, high pressures (or high vacuum levels), and high vibration environments, along with two corresponding connectors are disclosed. After brazing the edge-connect header components, the assembly is machined to form a slot with a portion of each of a plurality of electrical conductors removed in the machining process, resulting in a header with a high pin density. During the process of mating the first connector design to the edge-connect header, a plurality of wipers in the connector deflect, thereby causing the wipers to extend from the connector and contact the corresponding electrical conductors in the header. During the process of mating the second connector design to the edge-connect header, each of a plurality of wipers formed of low-mass, compliant metal wool, forms multiple contact points with a corresponding electrical conductor in the header.

Abstract: The present invention provides systems, devices and methods for detecting the presence and/or absence of one or more allergens in a sample particularly a food sample. The detection system includes a separate sample pickup, one or more disposables for receiving and processing a test sample and a detection device that can execute an allergen detection testing in minutes. The present detection system and device is compact and portable.

Abstract: The invention provides expression vectors, nucleic acids, vector particles and methods of treatment involving these vector particles, comprising an engineered KCNA1 gene encoding an edited Kv1.1 potassium channel, as well as methods of confirming the presence of engineered KCNA1 mRNA in a cell. The features of the engineered KCNA1 gene combine to advantageously enhance the translation and activity of the Kv1.1 protein and improve detection of KCNA1 gene expression in a cell and can be used for example in the treatment of epilepsy and similar neurological disorders.

Abstract: The present invention provides systems, devices and methods for detecting the presence and/or absence of one or more allergens in a sample particularly a food sample. The detection system includes a separate sample pickup, one or more disposables for receiving and processing a test sample and a detection device that can execute an allergen detection testing in minutes. The present detection system and device is compact and portable.

Abstract: This disclosure relates to a system for the collection and removal of fats, oils, and greases (FOG) including a collection container including a sealable liner having a bag shape and configured to be inserted into the interior of the collection container and removable from the collection container. The system may also include a collection receptacle and a receptacle cover retractably attachable to the collection receptacle and configured to cover the top opening, a bag trough disposed within the receptacle interior, a filter screen to filter FOG, a liner basket contained in the collection interior configured to hold liner(s) for removal from the collection receptacle; a bag wiper configured to push the liner from the bag trough into the liner basket, and a tank heater configured to heat the receptacle interior.