Abstract: The present invention discloses a wireless bio-signal monitoring system for monitoring a patient's bio-signal. The system includes a bio-signal capture unit, an analysis unit, a wireless transmission unit, a receiver unit and a remote database. With a chaotic phase space difference algorithm, the consumption of system resources can be minimized and the power management of the monitoring system can be optimized. By capturing position coordinates of the receiver unit via the Internet, we can locate the position of the patient to provide medical treatments immediately in an emergency situation.

Abstract: An optical waveguide SPR sensor is adapted for differential measurement. The optical waveguide SPR sensor includes a base, a bottom layer, and at least one set of optical waveguide layers. The set of the optical waveguide layers includes a measuring optical waveguide channel and a reference optical waveguide channel. The measuring optical waveguide channel includes an SPR sensing film layer. The measuring optical waveguide channel and the reference optical waveguide channel are independently configured and substantially parallel one to another. The bottom layer has a refractive index higher than a refractive index of the optical waveguide layer.

Abstract: Surface plasmon resonance (SPR) sensing technique which provides high specificity and accuracy has been an important method for molecular sensing technology. In the past, in order to affix 45 nm gold film onto glass or silicon substrate, several nanometers of chromium (Cr) or titanium (Ti) has been used as adhesive layer for the attachment of Au film. However, the existence of Cr or Ti thin film deteriorates the performance of SPR sensor due to their characteristic optical absorption. Our experimental results have confirmed the uses of conducting metal oxide, specifically, ITO and Zinc Oxide (ZnO) can be used to replace Cr or Ti for better performance in terms of SPR resonant properties (resonant angle and HMBW) and sensitivity enhancement for 3 to 15 times than traditional ones. It would contribute significantly to the SPR applications in both biosensors and gas sensors.

Abstract: A detecting device for detecting an autonomic nervous state of an examinee includes a measuring unit, an analog-to-digital converting (ADC) unit and a digital processing unit. The measuring unit measures a vital sign of the examinee to output a vital sign signal. The ADC unit is coupled to the measuring unit for receiving and converting the vital sign signal from analog to digital to output a digitalized vital sign signal. The digital processing unit is coupled to the ADC unit for receiving and processing the digitalized vital sign signal to obtain a detecting result. The detecting result represents the autonomic nervous state and organic states of the examinee.

Abstract: Surface plasmon resonance (SPR) sensing technique which provides high specificity and accuracy has been an important method for molecular sensing technology. In the past, in order to affix 45 nm gold film onto glass or silicon substrate, several nanometers of chromium (Cr) or titanium (Ti) has been used as adhesive layer for the attachment of Au film. However, the existence of Cr or Ti thin film deteriorates the performance of SPR sensor due to their characteristic optical absorption. Our experimental results have confirmed the uses of conducting metal oxide, specifically, ITO and Zinc Oxide (ZnO) can be used to replace Cr or Ti for better performance in terms of SPR resonant properties (resonant angle and HMBW) and sensitivity enhancement for 3 to 15 times than traditional ones. It would contribute significantly to the SPR applications in both biosensors and gas sensors.

Abstract: The present invention relates to a method for analyzing bio-signal instantaneously by Chaotic Phase Space Difference (CPSD) operation and its measure analyze device. This method includes time-delay procedure and rebuilt phase space matrix to calculate chaos of phase space matrix and diagnose the bio-signal. This method can also be used as an analyze method in portable device or 24 h ECG recorder which is a fast and convenient measure analyze device.

Abstract: The present invention relates to a dual-band micro-planar inverted F antenna (MPIFA), which is made based on a new type of printed circuit board (PCB), and its identification method to all different biomolecular concentration. This device works under 3 GHz and 7 GHz microwave frequency bands, and can predict the relationship for different absorbed biomolecular concentrations versus frequencies with the impedance value, dB(S(1,1)) parameter, and the variance of phase versus the frequency obtained from the measurement.

Abstract: An optical waveguide SPR sensor is adapted for differential measurement. The optical waveguide SPR sensor includes a base, a bottom layer, and at least one set of optical waveguide layers. The set of the optical waveguide layers includes a measuring optical waveguide channel and a reference optical waveguide channel. The measuring optical waveguide channel includes an SPR sensing film layer. The measuring optical waveguide channel and the reference optical waveguide channel are independently configured and substantially parallel one to another. The bottom layer has a refractive index higher than a refractive index of the optical waveguide layer.

Abstract: The present invention provides a miniature surface plasmon resonance sensor chip that produces a plane light source with an organic optoelectronic material by an electro-luminescence method and excites a surface plasmon resonance wave to observe a signal variation at the surface of a sensor chip caused by the combining condition of surface bio-molecules and provide a more accurate miniature sensor in conformity with micro-channel.

Abstract: One embodiment of the present invention is a sensor for analyzing an analyte that includes: (a) an sensing element that is adapted to interface with the analyte; (b) an organic luminescent element that is adapted to excite surface plasmon resonance on the sensing element; and (c) a detector that is adapted to detect signals from the sensing element.

Abstract: A biomolecular sensor system utilizing a transverse propagation wave of surface plasmon resonance (SPR) is described. The system comprises: a substrate; a dielectric layer, having a groove therein and standing on top of the substrate; a sensing film layer, sitting at the groove; a pair of prism devices, each resting on one side of the groove and both separating a tunable distance. Besides, the sensor system further comprises a light source, a light detector (a frontend of which connecting to a spectrometer and a backend connecting to a differential amplifier) and a channel with a cover forming inside the groove for the acquisition of the reflected light from the prism devices. Since the sensor system is constructed by exploiting the SPR technique on the transverse propagation, a whole contact surface is under detection (parallel detection) which differentiates it from the traditional method of single-area SPR detection.

Abstract: The present invention is in related to a miniature surface plasmon resonance waveguide device with sinusoidal curvature compensation and at least comprises: a substract, a waveguide structure, a sensing film layer and a cover layer, wherein the waveguide structure is configured with the function of sinusoidal curvature compensation and installed above the substract, further that, the waveguide structure includes a light input port and a light output port; the sensing film layer is on a special region of the waveguide structure, the special region is a sensing region; the cover layer is upper than the substract and has an opening. By means of the optimal curve figure of the sinusoidal curvature compensation, attenuation of light energy can be minimized while in propagation, and allows the input and output of the light on the same side of the device.

Abstract: A microarray biochip workstation allowing positioning of chips, immobilization of molecules, mixing of sample solution, molecular interactions and washing and processing qualitative and quantitative analyses consists of a positioning device for holding a biochip, a mixing device for acting on the sample solution applied on the biochip, a pumping device for removing the sample solution from the biochip surface that does not react, and a reading device for detecting reaction results of the biochip. The workstation thus constructed provides an integrated and effective work interface.

Abstract: A biomolecular sensor system utilizing a transverse propagation wave of surface plasmon resonance (SPR) is described. The system comprises: a substrate; a dielectric layer, having a groove therein and standing on top of the substrate; a sensing film layer, sitting at the groove; a pair of prism devices, each resting on one side of the groove and both separating a tunable distance. Besides, the sensor system further comprises a light source, a light detector (a frontend of which connecting to a spectrometer and a backend connecting to a differential amplifier) and a channel with a cover forming inside the groove for the acquisition of the reflected light from the prism devices. Since the sensor system is constructed by exploiting the SPR technique on the transverse propagation, a whole contact surface is under detection (parallel detection) which differentiates it from the traditional method of single-area SPR detection.

Abstract: An improved linear wave guide type surface plasmon resonance (SPR) microsensor, particularly a microsensor employing a dual-opening multi-channel design, adopts a cross differential comparison to enhance the performance of the microsensor and uses a surface plated metal thin film to provide a wavelength absorption according to a SPR characteristic and match with an appropriate sized micro-channel to give a highly sensitive high-flux measurement. The invention applied in a water solution sample comprises: a substrate; a bottom layer contacting a surface of the substrate; at least one wave guide layer contacting the bottom layer and the other surface of the substrate; at least two SPR sensing areas on a surface opposite to the contact surface of the wave guide layer and the bottom layer; at least two SPR sensing film layers on a surface opposite to the contact surface of the two PRS sensing areas and the wave guide layer.

Abstract: The present invention is in related to a miniature surface plasmon resonance waveguide device with sinusoidal curvature compensation and at least comprises: a substract, a waveguide structure, a sensing film layer and a cover layer, wherein the waveguide structure is configured with the function of sinusoidal curvature compensation and installed above the substract, further that, the waveguide structure includes a light input port and a light output port; the sensing film layer is on a special region of the waveguide structure, the special region is a sensing region; the cover layer is upper than the substract and has an opening. By means of the optimal curve figure of the sinusoidal curvature compensation, attenuation of light energy can be minimized while in propagation, and allows the input and output of the light on the same side of the device.

Abstract: A digital amblyopia image aid system provided with individually adjustable function, the structure thereof at least consists of an original image input, a system processing center and an image output after adjusting, wherein the characteristics is the said system processing center can adjust on vision according to individual amblyopia patient, and simulate the image seen by the vision disabled through linear and non-linear method to determine and adjust the suitable image contrast intensification parameters according to users' image intensification effect requirement to enhance the image contrast information and provide optimal image effect, and the said system can be applied in electronic magnification system, added with internet function, making it become class instruction reading system for the vision disabled, while the digital signal processor (DSP) is used for outdoors and convenience increasing, which adds exclusive image contrast intensification function into portable aid to bring more convenience and

Abstract: A symmetric or asymmetric multilayer structure based on the technique of surface plasmon resonance (SPR) has been applied for modulation of resonant angle and wavelength. The fabrication of this invention can have nanoscale thin film layers up to several hundreds, while each layer has its own material of a high or low refractive index value, and the total layers in a thickness of tens to hundreds nanometers are grown in this single structure. This invention is intended for optimizing the scanning of mechanism by modulating SPR resonant angle and wavelength, and for developing the prospect of portable instruments.

Abstract: A symmetric or asymmetric multilayer structure based on the technique of surface plasmon resonance (SPR) has been applied for modulation of resonant angle and wavelength. The fabrication of this invention can have nanoscale thin film layers up to several hundreds, while each layer has its own material of a high or low refractive index value, and the total layers in a thickness of tens to hundreds nanometers are grown in this single structure. This invention is intended for optimizing the scanning of mechanism by modulating SPR resonant angle and wavelength, and for developing the prospect of portable instruments.

Abstract: A multi-function opto-electronic detection apparatus for detecting molecular characteristics of a test sample. The appratuses comprises functional mode subsystems including a detecting light source subsystem for generating sampling beams for illuminating the test sample; a manipulation optics subsystem for aligning the sampling beam onto the test sample; a target signal processing subsystem for analyzing target beams emerging from the test sample resulting from the illuminating of the sampling beam; and a sample fixation subsystem for holding the test sample. The detecting light source subsystem, manipulation optics subsystem and target signal processing subsystem are assembled into one of several possible optical sampling setups for the detection characteristics of the test sample. The functional mode setups include at least ellispometer, confocal image scanner, photon tunneling scanning microscope and interferometer.