Abstract: Provided is a junction. In one aspect, the junction includes a first member, the first member formed of a first material, and a second member overlapping with the first member, the second member formed of a second material, the first and second members defining an overlapping space. In accordance with this aspect, the junction additionally includes an expanded metal joint located in at least a portion of the overlapping space, the expanded metal joint comprising a metal that has expanded in response to hydrolysis.

Abstract: Provided is an interval control valve. The interval control valve, in one aspect, includes a tubular housing, the tubular housing having one or more openings extending there through, and a sliding sleeve positioned within the tubular, the sliding sleeve configured to move between a closed position closing a fluid path between the one or more opening and an interior of the tubular housing, and an open position opening the fluid path between the one or more openings and the interior of the tubular housing. The interval control valve according to this aspect additionally includes a tubular overlapping with the sliding sleeve, the sliding sleeve and the tubular defining an overlapping space, and an expanded metal joint located in at least a portion of the overlapping space, the expanded metal joint comprising a metal that has expanded in response to hydrolysis.

Abstract: Provided is a multilateral junction. The multilateral junction, in one aspect, includes a y-block. The multilateral junction additionally includes a mainbore leg coupled to the y-block, the mainbore leg defining a second overlapping space, and a lateral bore leg coupled to the y-block, the lateral bore leg defining a third overlapping space. The multilateral junction, in this aspect, additionally includes an expanded metal joint located in at least a portion of the second overlapping space or the third overlapping space, the expanded metal joint comprising a metal that has expanded in response to hydrolysis.

Abstract: Herein is reported a method for determining bacterial endotoxin at low concentrations in a sample of an antibody (that has been produced using bacterial cells) comprising the following steps in the following order: i) adding magnesium ions to the sample, ii) diluting the sample, iii) dialyzing the sample having a pH-value of 5.7-8.0 against an endotoxin-flee aqueous solution, and iv) determining bacterial endotoxin in the sample using a bacterial endotoxin test, particularly the Limulus amoebocyte lysate assay.

Abstract: The invention provides methods of characterising the mode of action of a test compound by exposing populations of a living system to control and treatment conditions, using an unlabeled and labeled isotope source materials. The measurement of the isotopomer distribution of metabolites reveals the effect of the test compounds on the metabolism in that living systems. Further embodiments include where the living system is a plant, fungus, invertebrate, bacteria or virus, and where the test compound is a screening lead in a pesticide product development program.

Abstract: Technologies and techniques for monitoring and correcting the obfuscation of vehicle-related data. Personal data may be removed from the transmitted vehicle-related data, and the vehicle-related data after the removal of the personal references may be combined to form a vehicle-related data set without personal references. A temporal and spatial obfuscation of the vehicle-related data set may be carried out without personal references based on an estimated size of a cluster of data-collecting vehicles for generating an anonymous data set. The anonymous data set, including the degree of obfuscation, may be provided to a data user and an actual cluster size for a spatial region based on the provided anonymous data sets may be determined and compared with the estimated cluster size used for the obfuscation of the anonymous data set. The comparison result may be then used to correct the obfuscation of the spatial region.

Abstract: Systems, methods, and non-transitory computer-readable media can receive sensor data providing information about an environment surrounding a vehicle to a first computing system and a second computing system associated with the vehicle, wherein the first computing system and the second computing system are each capable of generating navigation instructions for the vehicle based on the received sensor data. A first planned trajectory is determined based on the sensor data by the first computing system. The vehicle is navigated by the first computing system based on the first planned trajectory. Control of the vehicle is transitioned from the first computing system to the second computing system based on a failure associated with the first computing system. An emulated trajectory is determined based on data describing a current motion of the vehicle by the second computing system. The vehicle is navigated by the second computing system based on the emulated trajectory.

Abstract: A transparent illumination system and related light guide plate is provided. The system is configured to facilitate total internal reflection propagation of light through the light guide plate despite low index of refraction differences between the glass material of the light guide layer and the adjacent layer. The system includes a light source, such as a laser diode, and an optical element to fan out light from the light source in the plane of the light guide plate. The light guide plate includes internal light extraction features.

Abstract: A method for determining measurement points of an adapted measurement path for measuring a measurement object includes determining measurement points of an ideal measurement path. The method includes determining target measurement points of at least one guide path, which differs from the ideal measurement path. The method includes capturing actual measurement points along the at least one guide path using a coordinate measuring device. The method includes determining deviations between the target measurement points and the actual measurement points of the at least one guide path. The method includes determining the measurement points of the adapted measurement path by changing the measurement points of the ideal measurement path based on the deviations.

Abstract: A method of forming a plate for an article of footwear includes applying a first strand portion to a base layer including positioning adjacent segments of the first strand portion to form a first layer on the base layer. The adjacent segments of the first strand portion having a greater density across a width of the plate between a medial side and a lateral side at a midfoot region of the plate than at a forefoot region of the plate and at a heel region of the plate. The method also includes applying at least one of heat and pressure to the first strand portion and to the base layer to conform the first strand portion and the base layer to a predetermined shape.

Abstract: Embodiments of the disclosure are drawn to an enteral feeding device for hydrolyzing triglycerides in a nutritional formula. The device may include a body housing a chamber, an inlet configured to fluidly couple with a source of nutritional formula, and an outlet configured to fluidly couple with an enteral feeding tube. The device may include a headspace and a plurality of particles contained within the chamber, wherein the lipase is covalently bonded to the plurality of particles. The device may include an inlet filter located between the inlet and the chamber, wherein the inlet filter contains a first plurality of openings, and an outlet filter located between the chamber and the outlet, wherein the outlet filter has a second plurality of openings smaller than the plurality of particles.

Abstract: A sole structure for an article of footwear includes a chamber having a first barrier element, a second barrier element, and a tensile member. The tensile member is disposed within an interior void defined by the first barrier element and the second barrier element. The sole structure further includes a phase change material disposed within the interior void and operable between a first state in a first temperature range and a second state in a second temperature range. The first temperature range is from 30° C. to 35° C. and the second temperature range is from 35° C. to 42° C. The sole structure further includes an insulating member disposed between the chamber and a ground contacting surface.

Abstract: A stitched article includes a substrate and a first strand portion formed from a bundle of fibers. The substrate has a first region and a second region. The first strand portion is attached to the substrate in the first region and in the second region via a series of stitches formed with a thread and forms a first layer on the substrate. The article has a first concentration of the stitches in the first region along a first length of the strand portion and a second concentration of the stitches different than the first concentration in the second region along a second length of the first strand portion.

Abstract: Embodiments of the disclosure are drawn to an enteral feeding device for hydrolyzing triglycerides in a nutritional formula. The device may include a body housing a chamber, an inlet configured to fluidly couple with a source of nutritional formula, and an outlet configured to fluidly couple with an enteral feeding tube. The device may include a headspace and a plurality of particles contained within the chamber, wherein the lipase is covalently bonded to the plurality of particles. The device may include an inlet filter located between the inlet and the chamber, wherein the inlet filter contains a first plurality of openings, and an outlet filter located between the chamber and the outlet, wherein the outlet filter has a second plurality of openings smaller than the plurality of particles.

Abstract: Provided is a multilateral leg bore, a multilateral junction, and a well system. The multilateral leg bore, in one aspect, includes a unitary housing having a first end and a second opposing end defining a length (L). In accordance with this aspect, the multilateral junction includes three or more bores formed in the housing and extending along the length (L).

Abstract: Provided is a multilateral junction (MLT), a well system, and a method for forming a well system. The MLT, in one aspect, includes a y-block having a housing with a single first bore and second and third bores extending therein, the second and third bores defining second and third centerlines. The MLT, in this aspect, further includes a mainbore leg having a first mainbore leg end coupled to the second bore and a second opposing mainbore leg end, and a lateral bore leg having a first lateral bore leg end coupled to the third bore and a second opposing lateral bore leg end. In this aspect, the mainbore leg and the lateral bore leg are twisted with respect to the second and third bore such that a first plane taken through centerlines of the second opposing mainbore leg end and the second opposing lateral bore leg end is angled.

Abstract: Provided is a downhole tool, a y-block, a well system, and a method for forming a well system. The downhole tool, in one aspect, includes a bottom hole assembly (BHA) having an uphole end and a downhole end, and a shroud positioned around and proximate the downhole end of the BHA, the shroud operable to slide relative to the BHA. The downhole tool, in this aspect, may further include one or more shear features coupling the shroud to the downhole end of the BHA.

Abstract: Provided is a method for accessing a well system. The method, in one aspect, includes placing a multilateral junction proximate an intersection between a main wellbore and a lateral wellbore, the multilateral junction including a y-block, a mainbore leg coupled to a second bore of the y-block and extending into the main wellbore, and a lateral bore leg coupled to a third bore of the y-block and extending into the lateral wellbore. The method, in one aspect, further includes selectively accessing at least one of the main wellbore or the lateral wellbore with a fracturing string through the y-block.

Abstract: Provided is a y-block, a multilateral junction, and a method for forming a well system. The y-block, in one aspect, includes a housing having a first end and a second opposing end, and a single first bore extending into the housing from the first end, the single first bore defining a first centerline. The y-block according to this aspect further includes second and third separate bores extending into the housing and branching off from the single first bore, the second bore defining a second centerline and the third bore defining a third centerline, wherein the second and third centerlines are angled relative to one another.

Abstract: The present invention provides novel ROR gamma-t inhibitors and pharmaceutical compositions thereof, formula (A).