Abstract: Systems, apparatuses, and methods for implementing a hierarchical scheduler. In various implementations, a processor includes a global scheduler, and a plurality of independent local schedulers with each of the local schedulers coupled to a plurality of processors. In one implementation, the processor is a graphics processing unit and the processors are computation units. The processor further includes a shared cache that is shared by the plurality of local schedulers. Each of the local schedulers also includes a local cache used by the local scheduler and processors coupled to the local scheduler. To schedule work items for execution, the global scheduler is configured to store one or more work items in the shared cache and convey an indication to a first local scheduler of the plurality of local schedulers which causes the first local scheduler to retrieve the one or more work items from the shared cache.

Abstract: Systems, apparatuses, and methods for implementing a message passing system to schedule work in a computing system. In various implementations, a processor includes a global scheduler, and a plurality of local schedulers with each of the local schedulers coupled to a plurality of processors. The processor further includes a shared cache that is shared by the plurality of local schedulers. Also, a plurality of mailboxes are implemented to enable communication between the local schedulers and the global scheduler. To schedule work items for execution, the global scheduler is configured to store one or more work items in the shared cache and store an indication in a mailbox for a first local scheduler of the plurality of local schedulers. Responsive to detecting the message in the mailbox, the first local scheduler identifies a location of the one or more work items in the shared cache and retrieves them for scheduling locally.

Abstract: Bolt assemblies for firearms (e.g., bolt action firearms) and methods of assembling and disassembling same are disclosed herein. In particular aspects, bolt assemblies comprising a bolt body, a bolt handle, a bolt shroud, and a clip that secures the bolt shroud to the bolt body are disclosed. The bolt shroud preferably resists removal of the bolt handle from the bolt body.

Abstract: The invention provides a compound of formula (0): or a pharmaceutically acceptable salt, N-oxide or tautomer thereof; wherein: n is 1 or 2; X is CH or N; Y is selected from CH and C—F; Z is selected from C—Rz and N; R1 is selected from: -(Alk1)t-Cyc1; wherein t is 0 or 1; Optionally substituted C1-6 acyclic hydrocarbon groups R2 is selected from hydrogen; halogen; and C1-3 hydrocarbon groups optionally substituted with one or more fluorine atoms; R3 is hydrogen or a group L1-R7; R4 is selected from hydrogen; methoxy; and optionally substituted C1-3 alkyl; and R4a is selected from hydrogen and a C1-3 alkyl group; wherein Rz, Alk1, Cyc1, L1 and R7 are defined herein; provided that the compound is other than 6-benzyl-3-{2-[(2-methylpyrimidin-4-yl)amino]pyridin-4-yl}-7,8-dihydro-1,6-naphthyridin-5(6H)-one and 3-{2-[(2-methylpyrimidin-4-yl)amino]pyridin-4-yl}-7,8-dihydro-1,6-naphthyridin-5(6H)-one and salts and tautomers thereof.

Abstract: A method and system for identifying scale. The method may include disposing a fluid sampling tool into a wellbore. The fluid sampling tool may comprise at least one probe configured to fluidly connect the fluid sampling tool to a formation in the wellbore and at least one passageway that passes through the at least one probe and into the fluid sampling tool. The method may further comprise drawing a formation fluid, as a fluid sample, through the at least one probe and through the at least one passageway, perturbing the formation fluid, and analyzing the fluid sample in the fluid sampling tool for one or more indications of scale.

Abstract: A microfluidic device capable of trapping contents in a manner suitable for high-throughput imaging is described herein. The microfluidic device may include one or more trapping devices, with each trapping device having a plurality of trapping channels. The trapping channels may be configured to receive contents via an inlet channel that connects a sample reservoir to the trapping channels via fluid communication. The trapping channels are shaped such that contents within the trapping channels are positioned for optimal imaging purposes. The trapping channels are also connect to at least one exit channel via fluid communication. The fluid, and contents within the fluid, maybe controlled via hydraulic pressure.

Abstract: This disclosure provides a method for substantially increasing the concentration of cfDNA in a patient. By injecting a patient with lipid and/or polymer nanoparticles, agents that bind cfDNA, or inhibit deoxyribonucleases prior to collection of a sample of cfDNA, e.g., by way of a liquid biopsy, major pathways for the degradation of cfDNA are temporarily blocked, permitting transient accumulation of cfDNA. This strategy has the potential to dramatically enhance the quality of detection achieved by downstream cfDNA e analytical applications, such as sequencing applications.

Abstract: Exemplary systems and methods are directed to generating customized imagery includes receiving input parameters that define operations for one of plural disparate image processing tools in generating the customized imagery and define attributes of the customized imagery to be generated. Program code for generating an API is executed and the API establishes communication with each image processing tool. The API generates parameterized calls which provide instructions for a specified one of the image processing tools to generate the customized imagery. The image processing tool which receives the instructions is identified from the input parameters. The parameterized calls are sent to the parameterized calls to the image processing tool and the customized imagery is generated. The customized imagery is returned to the API and is stored in a database as training data for an artificial intelligence model.

Abstract: In some embodiments, a device for reinforcement of a facet joint is provided. The device comprises a lumen configured to receive a fastener member. In some embodiments, a second segment comprises a second lumen configured to receive a fastener member or fastener. In some embodiments, kits are provided with a fastener member and a facet reinforcement device. Methods are also provided for treating a spine. In some embodiments, the fastener member is placed through both articular processes of a facet joint and a facet reinforcement device.

Abstract: A grill plate includes a body having a top surface for supporting food, a grease trap associated with said body, a cavity defined by said grease trap, and an opening to said cavity disposed proximate said top surface.

Abstract: Hardware for implementing a Deep Neural Network (DNN) having a convolution layer. A plurality of convolution engines each perform a convolution operation by applying a filter to a data window. Each of the plurality of convolution engines includes multiplication logic that combines a weight of a filter with a respective data value of a data window; control logic that receives configuration information identifying a set of filters for operation on a set of data windows at the plurality of convolution engines; determines a sequence of convolution operations for evaluation at the multiplication logic; requests weights and data values for at least partially applying a filter to a data window; and causes the multiplication logic to combine the weights with their respective data values. Accumulation logic accumulates the results of a plurality of combinations performed by the multiplication logic to form an output for a convolution operation of the determined sequence.

Abstract: A nuclear reactor is designed to couple the load path of control elements with the reactor core, thus reducing opportunity for differential movement between the control elements and the reactor core. A core barrel can be fabricated in a manufacturing facility to include the reactor core, control element supports, and control element drive system. The core barrel can be mounted to a reactor vessel head. Movement, such as through seismic forces, transmits an equal direction and magnitude to the control elements and the reactor core, thus inhibiting the opportunity for differential movement.

Abstract: A display system of an aircraft includes a display device defining a display area, a vision system for generating an image of an operating environment of the aircraft on the display area, data processors operatively coupled to the display device and the vision system, and non-transitory machine-readable memory operatively coupled to the one or more data processors and storing instructions executable by the one or more processors and configured to cause the one or more processors to, when a condition of the aircraft is met, cause an alteration of a display of flight information on the display area to declutter a cutout region in the image generated by the vision system, the cutout region devoid of imaging generated by the vision system and displaying an Approach Lighting System (ALS) of a runway of intended landing for the aircraft.

Abstract: Systems and methods for heteroaromatic silicon fluoride compounds as radiopharmaceuticals with theranostic properties are described. The theranostic heteroaromatic silicon fluoride compounds can be conjugated with various disease binding ligands and/or chelators for imaging and therapeutic applications.

Abstract: Methods and systems for providing a user interface and workflow for interacting with time series data, and applying portions of time series data sets for refining regression models. A system can present a user interface for receiving a first user input selecting a first model from a list of models for modeling the apparatus, generate and display a first chart depicting a first time series data set depicting data from a first sensor, generate and display a second chart depicting a second time series data set depicting a target output of the apparatus, receive a second user input of a portion of the first time series data set, and generate and display a third chart depicting a third time series data set depicting an output of the selected model and aligned with the second chart of the target output and updated in real-time in response to the second user input.

Abstract: A display system of an aircraft includes a display device defining a display area, a vision system for generating an image of an operating environment of the aircraft on the display area, data processors operatively coupled to the display device and the vision system, and non-transitory machine-readable memory operatively coupled to the one or more data processors and storing instructions executable by the one or more processors and configured to cause the one or more processors to, when a condition of the aircraft is met, cause an alteration of a display of flight information on the display area to declutter a cutout region in the image generated by the vision system, the cutout region devoid of imaging generated by the vision system and displaying an Approach Lighting System (ALS) of a runway of intended landing for the aircraft.

Abstract: Hardware for implementing a Deep Neural Network (DNN) having a convolution layer, the hardware comprising a plurality of convolution engines each configured to perform convolution operations by applying filters to data windows, each filter comprising a set of weights for combination with respective data values of a data window; and one or more weight buffers accessible to each of the plurality of convolution engines over an interconnect, each weight buffer being configured to provide weights of one or more filters to any of the plurality of convolution engines; wherein each of the convolution engines comprises control logic configured to request weights of a filter from the weight buffers using an identifier of that filter.

Abstract: A sample analyzer is configured to obtain first and second stage position data. The first stage position data indicates a first position of a movable stage in a first dimension, and the second stage position data indicates a second position of the movable stage in a second (perpendicular) dimension. The sample analyzer is configured to, based on the first and second stage position data, determine a viewing position of one or more viewing or imaging optics relative to the movable stage. The sample analyzer is configured to display a vessel map, which comprises a visual representation of a sample vessel associated with the movable stage. The sample analyzer is configured to display a viewing position marker overlaid on the vessel map. The viewing position marker indicates the viewing position of the one or more viewing or imaging optics relative to the sample vessel as represented by the vessel map.

Abstract: An example hinged device flexible substrate testing system includes: a first plate comprising a first surface configured to hold stationary a first side of a hinged device under test; a second plate comprising a second surface configured to hold a second side of the hinged device under test; a first cam follower coupled to the second plate; a first drive arm configured to move the first cam follower to cause the second plate to rotate about a hinge pivot axis of the hinged device under test; an actuator configured to rotate the drive arm; and a load cell configured to measure loads on the first plate while the actuator moves the second plate.