Abstract: A method of applying a dielectric coating on a structure array of a component of an electrical device includes applying a first layer of a first dielectric material on a structure array with an atomic layer deposition (ALD) process or a spin-on cladding process. The structure array has a plurality of features. The method may include applying a second layer of a second dielectric material on the first layer with an evaporation deposition process, a physical vapor deposition process (PVD), or a flux-controlled chemical vapor deposition (CVD) process. The first layer has a first thickness and the second layer has a second thickness that is greater than the first thickness.

Abstract: Materials and methods for producing tactile anatomical structures are described. These are intended primarily for use for high-value, in-depth surgical training for novice or expert surgeons. They may also be used for medical education, sales demonstrations, or for research and development. Examples of embodiments refer to their use in knee and shoulder models. The tactile tissue-simulating structures include, amongst others: skin, fat, muscles, ligaments, tendons, cartilage, bursa, fat pad, and periosteum. A method for creating a musculotendinous junction is also described.

Abstract: In an example embodiment, an apparatus for making pouch products includes a conveyor system. The conveyor system includes a first receiving location along a path of the conveyor system, and a dosing location along the path of the conveyor system. The apparatus also includes a first material dispensing station configured to transfer a first material to the first receiving location. The first material includes a first elastic layer and a first support layer. The first material dispensing station includes a dispenser roller configured to hold a roll of the first material, a plurality of rollers configured to convey the first material from the dispenser roller to the first receiving location, and a stripper plate configured remove at least a portion of the first support layer from a portion of the first elastic layer.

Abstract: A turbine engine and method of operating includes an engine core with a compressor, a combustor, and a turbine in axial flow arrangement. A flow path extends through the engine core from the compressor to the turbine to define a flow direction for a working airflow through the engine core.

Abstract: Compounds that inhibit KRas G12D. In particular, compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor, and in particular, methods of treating cancer. The compounds have a general structure represented by Formula (I): or a pharmaceutically acceptable salt thereof.

Abstract: To enable a patron of a venue attending a performance to feel as if he or she is ‘front and center’ even if located much farther away or angled from a stage of the venue, system and methods that enhance audio quality of audio signals especially over the voice frequency spectrum to generate a processed audio signal including an increased voice frequency spectrum are provided. The processed audio signal may be communicated to a receiving system with a headset or other transducer (e.g., loudspeakers) that allows for ambient sounds to be heard by a patron and for the patron to control volume of the processed audio signal, thereby mixing the processed audio signal with the ambient sounds. The receiving system may be rented and an operator may control usage for both performance or long-term rentals using various control features of the processed audio signals and/or receiving system.

Abstract: A device for sealing an aperture in a tissue includes: a foot including a distal portion configured to be disposed distal to the tissue when the device is implanted in a position to seal the aperture; and a flexible wing positionable against a distal surface of the tissue adjacent the aperture such that the flexible wing is disposed between the distal portion of the foot and the distal surface adjacent the aperture.

Abstract: A system for content presentation is disclosed. According to one embodiment, the system includes Input/Output(I/O) circuitry to receive an indicated location and an indicated one or more preferred sources of content. Memory stores scheduling information that includes a location information and date information associated therewith. A processor identifies at least one media segment for inclusion into a customized media programming stream based on (a) comparing the indicated location to the location information; (b) comparing the current date to the associated date information; and (c) comparing the indicated one or more preferred sources for content to the content source information. The processer assembles a customized media programming stream by adding the at least one identified media segment to the customized media programming stream. The I/O circuitry transmits the customized media programming stream for presentation on a user device.

Abstract: An intravascular catheter for peri-vascular and/or peri-urethral tissue ablation includes multiple needles advanced through supported guide tubes which expand around a central axis to engage the interior surface of the wall of the renal artery or other vessel of a human body allowing the injection an ablative fluid for ablating tissue, and/or nerve fibers in the outer layer or deep to the outer layer of the vessel, or in prostatic tissue. The system may also include a means to limit and/or adjust the depth of penetration of the ablative fluid into and beyond the tissue of the vessel wall. The catheter may also include structures which provide radial and/or lateral support to the guide tubes so that the guide tubes expand uniformly and maintain their position against the interior surface of the vessel wall as the sharpened injection needles are advanced to penetrate into the vessel wall.

Abstract: Apparatuses, systems, and techniques to render computer graphics. In at least one embodiment, a first one or more lights are selected from among lights in a virtual scene to be rendered as a frame of graphics, and a second one or more lights are selected from among lights used to render one or more pixels in at least one of a prior frame or the current frame. A pixel of the current frame is rendered using the first and second one or more lights, and a light is selected for reuse in rendering a subsequent frame from among the first and second one or more lights.

Abstract: In an example embodiment, an apparatus for making pouch products includes a conveyor system. The conveyor system includes a first receiving location along a path of the conveyor system, and a dosing location along the path of the conveyor system. The apparatus also includes a first material dispensing station configured to transfer a first material to the first receiving location. The first material includes a first elastic layer and a first support layer. The first material dispensing station includes a dispenser roller configured to hold a roll of the first material, a plurality of rollers configured to convey the first material from the dispenser roller to the first receiving location, and a stripper plate configured remove at least a portion of the first support layer from a portion of the first elastic layer.

Abstract: A system and a method are disclosed for enabling seamlessly tracking a location of a water vessel by supplementing satellite data with mobile data location based on proximity of a water vessel to shore. The system receives a Global Positioning System (GPS) location of the water vessel, the GPS location of the water vessel based on using the satellite data of the water vessel. The system determines that the GPS location is within a threshold distance of a boundary. Responsive to determining that the GPS location is within the threshold distance of the boundary, the system initiates monitoring for a mobile signal emanating from a trajectory path of the water vessel. The system detects, during the monitoring, the mobile signal, the tracking the location of the water vessel based on mobile data of the mobile signal. The system provides the tracked location to a monitoring device.

Abstract: Disclosed approaches may leverage the actual spatial and reflective properties of a virtual environment—such as the size, shape, and orientation of a bidirectional reflectance distribution function (BRDF) lobe of a light path and its position relative to a reflection surface, a virtual screen, and a virtual camera—to produce, for a pixel, an anisotropic kernel filter having dimensions and weights that accurately reflect the spatial characteristics of the virtual environment as well as the reflective properties of the surface. In order to accomplish this, geometry may be computed that corresponds to a projection of a reflection of the BRDF lobe below the surface along a view vector to the pixel. Using this approach, the dimensions of the anisotropic filter kernel may correspond to the BRDF lobe to accurately reflect the spatial characteristics of the virtual environment as well as the reflective properties of the surface.

Abstract: System, methods, and non-transitory, machine-readable media to facilitate state-based content composite generation with respect to digitally distributed content are disclosed. Electronic communications received via interfaces may be detected. Signals of events that are specified for digital distribution from events may be detected. Data changes that are generated based on an event may be detected. A specification of criteria that apply to the data changes may be identified. A content composite may be created. An adaptable content object may be identified. The adaptable content object may be configured with a content object so that the content composite. The content composite may be output for presentation so that the endpoint media device performs an operation relating to the content composite. A signal corresponding to the operation that is indicative of activation of an interface option may be processed.

Abstract: Disclosed herein are systems and methods for serial flow emulsion processes. Systems and methods as described herein result in reduced cross-contamination.

Abstract: A system and a method are disclosed for enabling assignment of a responder unit to a user on a water vessel. The rescue system transmits a Short Message Service (SMS) message to a user device on the water vessel, the SMS message comprising a selectable option that, when selected, causes a location of the user device to be shared. Based on a selection by a user of the user device of the selectable option, the system receives a plurality of location coordinates from the user device at a plurality of respective times, each respective location coordinate describing a respective location of the user device at its respective time. The system selects a responder unit to assign to the user based on the plurality of location coordinates and a location of each of a plurality of candidate responder units. The system transmits location information to a responder device of the selected responder unit, the location information based on the plurality of location coordinates.

Abstract: A system and a method are disclosed for enabling accurate estimation of a location of a water vessel. In an embodiment, a rescue system transmits a Short Message Service (SMS) message to a user device on the water vessel, the SMS message comprising a selectable option that, when selected, causes a location of the user device to be shared. Based on a selection by a user of the user device of the selectable option, the system receives a plurality of location coordinates from the user device at a plurality of respective times, each respective location coordinate describing a respective location of the user device at its respective time. The system computes an estimated location of the water vessel based on the plurality of location coordinates and an elapsed time between a current time and a time at which a last-received location coordinate was received. The system transmits the estimated location to a responder device.

Abstract: A parking availability predictor system provides a prediction of parking availability that meets a user's specified needs. When the user submits a query for parking availability, he can include desired parking criteria such as location, handicapped status, and desired time to begin parking. The system consults a parking occupancy model which gathers current and historical information about parking occupancy, including parking durations and durations of vacancies between occupancies. The model processes the gathered information into a statistical predictor of parking occupancy and vacancy. The system uses the predictor to predict when parking that meets the user's needs will become available. That prediction, including user-suitable parking locations along with the expected start of their vacancies, is then sent to the user in answer to his query.

Abstract: This application discloses techniques for generating and querying projective hash maps. More specifically, projective hash maps can be used for spatial hashing of data related to N-dimensional points. Each point is projected onto a projection surface to convert the three-dimensional (3D) coordinates for the point to two-dimensional (2D) coordinates associated with the projection surface. Hash values based on the 2D coordinates are then used as an index to store data in the projective hash map. Utilizing the 2D coordinates rather than the 3D coordinates allows for more efficient searches to be performed to locate points in the 3D space. In particular, projective hash maps can be utilized by graphics applications for generating images, and the improved efficiency can, for example, enable a game streaming application on a server to render images transmitted to a user device via a network at faster frame rates.

Abstract: Provided herein is a method of characterising a target polynucleotide as it moves with respect to a nanopore using a motor protein. Also provided are polynucleotide adapters and kits comprising such adapters. The methods, kits and adapters find use in characterising polynucleotides, for example in sequencing.