Abstract: This application discloses techniques for generating and querying projective hash maps. More specifically, projective hash maps can be used for spatial hashing of data related to N-dimensional points. Each point is projected onto a projection surface to convert the three-dimensional (3D) coordinates for the point to two-dimensional (2D) coordinates associated with the projection surface. Hash values based on the 2D coordinates are then used as an index to store data in the projective hash map. Utilizing the 2D coordinates rather than the 3D coordinates allows for more efficient searches to be performed to locate points in the 3D space. In particular, projective hash maps can be utilized by graphics applications for generating images, and the improved efficiency can, for example, enable a game streaming application on a server to render images transmitted to a user device via a network at faster frame rates.

Abstract: Provided herein is a method of characterising a target polynucleotide as it moves with respect to a nanopore using a motor protein. Also provided are polynucleotide adapters and kits comprising such adapters. The methods, kits and adapters find use in characterising polynucleotides, for example in sequencing.

Abstract: Provided herein are methods and composition for immune repertoire sequencing and single cell barcoding. The methods and compositions can be used to pair any two sequences originating from a single cell, such as heavy and light chain antibody sequences, alpha and beta chain T-cell receptor sequences, or gamma and delta chain T-cell receptor sequences, for antibody and T-cell receptor discovery, disease and immune diagnostics, and low error sequencing.

Abstract: A cover system for selectively blocking insertion of unauthorized objects through an aperture of a restraint mount of a patient support apparatus is provided. The cover system includes a cover and an instrument having an interface. The cover includes a brace and a restrictor coupled to the brace. The brace attaches to the patient support apparatus adjacent to the aperture and the restrictor operates in a restrict mode blocks access to the aperture and a permit mode where the restrictor permits access to the aperture. The cover also includes a lock mechanism, which includes a keeper movable between a locked state where movement of the restrictor is inhibited and an unlocked state where movement of the restrictor is permitted. The keeper moves from the locked state to the unlocked state in response to selective engagement between the interface of the instrument and a receiver of the lock mechanism.

Abstract: A custom oral device is provided that fits on the maxillary or mandibular arch of a wearer. The oral device comprises a tray that corresponds with the shape and size of a wearer's oral anatomy. A soft liner is disposed within an occlusal channel of the tray having an upper surface that comprises an impression having features that correspond to at least a portion of the wearer's dentition and in which the wearer's teeth align. An apparatus and a method for making the custom oral device are provided.

Abstract: The present disclosure is directed to systems and methods for automatically shutting off fluid flow through a fluid inlet line of a water heater upon detection of a leak of the water heater. The system may include an electrically powered shutoff assembly operatively coupled to the fluid inlet line, and a capacitor operatively coupled to the electrically powered shutoff assembly. The electrically powered shutoff assembly may be configured to shut off fluid flow through the fluid inlet line upon detection of a leak of the water heater, and the capacitor may be configured to store power received from an external power source. Accordingly, when the electrically powered shutoff assembly does not have access to electric power, the capacitor may power the electrically powered shutoff assembly to shut off fluid flow through the fluid inlet line.

Abstract: A pressure relief valve comprises a base attachable to the pressure vessel at a vessel aperture, the base comprising a base face, the base face facing away from the vessel; a cap comprising a cap face, the cap face facing towards the vessel, the cap movable between an open position and a closed position, wherein in the closed position the cap seals the vessel aperture and in the open position flow through the vessel aperture is permitted to relieve pressure in the pressure vessel; and a gasket between the base face and the cap face, wherein in the closed position: the base face and the cap face contact the gasket at a first location to form a first seal; and the base face and the cap face contact the gasket at a second location to form a second seal.

Abstract: The present disclosure is directed to a mechanical and powerless leak detection and shutoff system that may be used in any commercially available water heater, e.g., both gas and electric. The system includes a spring-loaded shutoff assembly having a valve member operatively coupled to a fluid inlet line of the water heater. A handle of the shutoff assembly is maintained in an open configuration via a latching mechanism until a force is applied to cause the latching mechanism to release the handle and actuate the valve member to shutoff fluid flow through the fluid inlet line. The shutoff assembly is operatively coupled to a leak detection assembly via a cable. The leak detection assembly uses a fluid-soluble material that dissolves when exposed to fluid to thereby pull the cable to apply the force to disengage the latching mechanism.

Abstract: Thermoplastic compositions include: (a) from about 20 wt % to about 50 wt % post-consumer recycled polycarbonate (PCR-PC); (b) from about 5 wt % to about 25 wt % of a filler component; (c) from about 4 wt % to about 7 wt % of a phosphazene component; (d) from about 20 wt % to about 65 wt % of a polycarbonate copolymer component; and (e) from about 1 wt % to about 20 wt % one or more additional components. The polycarbonate copolymer component includes bisphenol-A and a monomer comprising one or more of 3,3-Bis(4-hydroxyphenyl)-2-phenyl-2,3-dihydro-isoindol-1-one (PPPBP), 4-4-(3-3-5 trimethylcyclohexane-1-ldiyl)diphenol (BPI), 4,4?-(1-Methyl Ethyl) 1-3-cyclohexandiyl) Bis-Phenol (BHPM), 1,1-Bis(4-hydroxy-3-methyl phenyl) cyclohexane (DMBPC); 4-[1-(4-hydroxyphenyl)cyclododecyl]phenol (Red Cross), bisphenol based on cyclooctadiene, bisphenol based on isophorone nitrile, and combinations thereof.

Abstract: Provided herein is a method of reducing or preventing sunburn caused from visible and ultraviolet radiation in a subject, the method comprising topically applying to the subject a sunscreen composition comprising at least one inorganic UV filtering agent selected from zinc oxide or titanium dioxide; at least one inorganic pigment selected from iron oxide; and at least two visible light protecting agents comprising barium sulfate and mica; wherein the at least two visible light protecting agents are present in an amount effective to reduce or prevent sunburn caused from visible light. Also provided herein are sunscreen compositions and methods of increasing the visible light protection factor of a sunscreen composition.

Abstract: A connector comprises a housing defining a receptacle sized to receive a flat flexible cable. A conductive terminal is arranged within the receptacle and adapted to contact an exposed conductor of the flat flexible cable received within the receptacle. A seal is positioned in contact with a front end of the housing and defines a cable receiving slot therethrough aligned with the receptacle. A cover is arranged over the seal and includes a slotted opening aligned with the cable receiving slot of the seal and the receptacle. The cover selectively fixed to the front end of the housing.

Abstract: The present invention provides, in part, compounds of Formula I: or an N-oxide thereof, or a pharmaceutically acceptable salt of the compound or the N-oxide, wherein: R1, R2, L, A, and E are as described herein; processes for the preparation of; intermediates used in the preparation of; and compositions containing such compounds, N-oxides, or salts, and their uses for treating M4-mediated (or M4-associated) disorders including, e.g., Alzheimer's Disease, schizophrenia (e.g., its cognitive and negative symptoms), pain, addiction, and a sleep disorder.

Abstract: Separators and additives (e.g., electrode additives) for use in energy storage devices are disclosed. In certain embodiments, a separator includes inorganic particles. In certain embodiments, an additive includes inorganic particles. The additive may be used in an electrode, such as a cathode or anode in a battery. The inorganic particles (whether included in a separator or used in (e.g., as) an additive, for example for an electrode) may be functional inorganic particles that promote battery performance and/or safety. For example, the functional inorganic particles may act to reduce or eliminate side reactions or mitigate the effects of side reactions during electrochemical cycling of an energy storage device in which they are included (e.g., discharge and/or charge of a battery). As another example, the functional inorganic particles may additionally or alternatively promote ionic conductivity.

Abstract: A riflescope having a display that provides information to a user of the riflescope, along with related methods, is provided herein. In one embodiment, a riflescope includes an objective system and an ocular system, wherein a focal plane is defined between the objective system and the ocular system. A display system, comprising a display and a mirror, is positioned at a location between the focal plane and the ocular system. In one embodiment, the distance between the focal plane and the ocular system is equal to a sum of a distance between the display and the mirror and a distance between the mirror and the ocular system.

Abstract: A dynamic multi-pane insulating assembly and system including methods for dynamically maintaining the thermal resistance value of the assembly and system. The dynamic multi-pane insulating assembly and system includes first and second gas permeable panes defining an evacuated gap in communication with a vacuum source; a first exterior pane spaced from the first gas permeable pane defining a first pressurized gap in communication with a source of pressurized gas; and a second exterior pane spaced from the second gas permeable pane defining a second pressurized gap in communication with the source of pressurized gas.

Abstract: A patient support apparatus includes a support structure having a patient support deck and a side rail coupled to the support structure. The side rail is movable relative to the support structure. A lock releasably locks the side rail in one or more side rail positions, such as in a raised position and an intermediate position. A manual release is coupled to the side rail and operable to unlock the side rail. A bypass lever is provided to allow a user to raise the side rail from a lowered position to the raised position without locking in the intermediate position. A damper is located inside the side rail to counterbalance the weight of the side rail and assist the user in raising the side rail, bi-directionally. The side rail is formed of first and second walls that are heat staked together to form a lightweight side rail of suitable strength.

Abstract: A system and a method are disclosed for a vehicle control and interface system configured to facilitate control of different vehicles through universal mechanisms. The vehicle control and interface system can be integrated with different types of vehicles (e.g., rotorcraft, fixed-wing aircraft, motor vehicles, watercraft, etc.) in order to facilitate operation of the different vehicles using universal vehicle control inputs. In particular, the vehicle control and interface system converts universal vehicle control inputs describing a requested trajectory of a vehicle received from one or more universal vehicle control interfaces into commands for specific actuators of the vehicle configured to adjust a current trajectory of the vehicle to the requested trajectory. In order to convert the universal vehicle control inputs to actuator commands the vehicle control and interface system processes the universal vehicle control inputs using a universal vehicle control router.

Abstract: A ferrule system includes: a first ferrule comprising a proximal end for engaging a first implement and a threaded portion opposite the proximal end; and a second ferrule comprising a distal portion for engaging a second implement, a proximal portion opposite the distal portion and comprising teeth, a threaded portion intermediate the distal portion and proximal portion and configured to engage the threaded portion of the first ferrule. Teeth are mounted on the first ferrule and are biased to automatically engage the teeth of the proximal portion of the second ferrule as the threaded portion of the first ferrule engages the threaded portion of the second ferrule such that only tightening rotation of the second ferrule relative to the first ferrule is permitted when the teeth mounted on the first ferrule are automatically engaged with the teeth of the proximal portion of the second ferrule.

Abstract: A system and a method are disclosed for enabling assignment of a responder unit to a user on a water vessel. The rescue system transmits a Short Message Service (SMS) message to a user device on the water vessel, the SMS message comprising a selectable option that, when selected, causes a location of the user device to be shared. Based on a selection by a user of the user device of the selectable option, the system receives a plurality of location coordinates from the user device at a plurality of respective times, each respective location coordinate describing a respective location of the user device at its respective time. The system selects a responder unit to assign to the user based on the plurality of location coordinates and a location of each of a plurality of candidate responder units. The system transmits location information to a responder device of the selected responder unit, the location information based on the plurality of location coordinates.

Abstract: Updates to a hierarchical data structure may be selectively replicated to other replicas of the hierarchical data structure. An update for a hierarchical data structure may be received and committed to the hierarchical data structure. A determination as to whether any other replicas of the hierarchical data structure have permission to receive the update may be made. For those replicas of the hierarchical data structure with permission to receive the update, the update may be provided to the replicas and committed to the replicas. Different types of replication techniques may be implemented, such as pull-based replication techniques or push-based replication techniques. Replication permissions for objects of the hierarchical data structure may be individually defined, in some embodiments.