Patents by Inventor Claes Gustafsson

Claes Gustafsson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for making character strings, polynucleotides and polypeptides having desired characteristics
    Publication number: 20020183934
    Abstract: “In silico” nucleic acid recombination methods, related integrated systems utilizing genetic operators and libraries made by in silico shuffling methods are provided.
    Type: Application
    Filed: January 18, 2000
    Publication date: December 5, 2002
    Inventors: Sergey A. Selifonov, Willem P.C. Stemmer, Claes Gustafsson, Matthew Tobin, Stephen del Cardayre, Phillip A. Patten, Jeremy Minshull
  • Oligonucleotide mediated nucleic acid recombination
    Patent number: 6479652
    Abstract: Methods of recombining nucleic acids, including homologous nucleic acids, are provided. Families of gene shuffling oligonucleotides and their use in recombination procedures, as well as polymerase and ligase mediated recombination methods are also provided.
    Type: Grant
    Filed: July 27, 2000
    Date of Patent: November 12, 2002
    Assignee: Maxygen, Inc.
    Inventors: Andreas Crameri, Willem P. C. Stemmer, Jeremy Minshull, Steven H. Bass, Mark Welch, Jon E. Ness, Claes Gustafsson, Phillip A. Patten
  • Triazine degrading enzymes
    Publication number: 20020155571
    Abstract: New triazine hydrolases, (both nucleic acids and proteins) are provided. Compositions which include these new proteins and/or genes, recombinant cells, shuffling methods involving the new triazine hydrolases, antibodies to the new triazine hydrolases and methods of using the triazine hydrolases are also provided.
    Type: Application
    Filed: February 28, 2001
    Publication date: October 24, 2002
    Inventors: Sun Ai Raillard, Jeremy Minshull, Claes Gustafsson
  • Use of codon-varied oligonucleotide synthesis for synthetic shuffling
    Patent number: 6436675
    Abstract: Methods of providing shuffling libraries that include codon-varied oligonucleotide sequences are described. Codon-varied oligonucleotides are synthesized using trinucleotide or mononucleotide phosphoramidite sequences, and are derived from homologous or non-homologous nucleic acid sequences, or combinations of such sequences. Various methods of recombining codon-varied oligonucleotide sequences to expedite artificial evolution are also described. The present invention additionally relates to various integrated systems that are optionally used to automate these recombination methods.
    Type: Grant
    Filed: September 28, 1999
    Date of Patent: August 20, 2002
    Assignee: Maxygen, Inc.
    Inventors: Mark Welch, Jon Ness, Claes Gustafsson, Willem P. C. Stemmer, Jeremy Minshull
  • Oligonucleotide mediated nucleic acid recombination
    Patent number: 6426224
    Abstract: Methods of recombining nucleic acids, including homologous nucleic acids, are provided. Families of gene shuffling oligonucleotides and their use in recombination procedures, as well as polymerase and ligase mediated recombination methods are also provided.
    Type: Grant
    Filed: July 27, 2000
    Date of Patent: July 30, 2002
    Assignee: MaxyGen, Inc.
    Inventors: Andreas Crameri, Willem P. C. Stemmer, Jeremy Minshull, Steven H. Bass, Mark Welch, Jon E. Ness, Claes Gustafsson, Phillip A. Patten
  • Oligonucleotide mediated nucleic acid recombination
    Patent number: 6423542
    Abstract: Methods of recombining nucleic acids, including homologous nucleic acids, are provided. Families of gene shuffling oligonucleotides and their use in recombination procedures, as well as polymerase and ligase mediated recombination methods are also provided.
    Type: Grant
    Filed: July 27, 2000
    Date of Patent: July 23, 2002
    Assignee: Maxygen, Inc.
    Inventors: Andreas Crameri, Willem P. C. Stemmer, Jeremy Minshull, Steven H. Bass, Mark Welch, Jon E. Ness, Claes Gustafsson, Phillip A. Patten
  • Oligonucleotide mediated nucleic acid recombination
    Patent number: 6376246
    Abstract: Methods of recombining nucleic acids, including homologous nucleic acids, are provided. Families of gene shuffling oligonucleotides and their use in recombination procedures, as well as polymerase and ligase mediated recombination methods are also provided.
    Type: Grant
    Filed: September 28, 1999
    Date of Patent: April 23, 2002
    Assignee: Maxygen, Inc.
    Inventors: Andreas Crameri, Willem P. C. Stemmer, Jeremy Minshull, Steven H. Bass, Mark Welch, Jon E. Ness, Claes Gustafsson, Phillip A. Patten
  • Oligonucleotide mediated nucleic acid recombination
    Patent number: 6368861
    Abstract: Methods of recombining nucleic acids, including homologous nucleic acids, are provided. Families of gene shuffling oligonucleotides and their use in recombination procedures, as well as polymerase and ligase mediated recombination methods are also provided.
    Type: Grant
    Filed: January 18, 2000
    Date of Patent: April 9, 2002
    Assignee: Maxygen, Inc.
    Inventors: Andreas Crameri, Willem P. C. Stemmer, Jeremy Minshull, Steven H. Bass, Mark Welch, Jon E. Ness, Claes Gustafsson, Phillip A. Patten
  • Oligonucleotide mediated nucleic acid recombination
    Patent number: 6319714
    Abstract: Methods of recombining nucleic acids, including homologous nucleic acids, are provided. Families of gene shuffling oligonucleotides and their use in recombination procedures, as well as polymerase and ligase mediated recombination methods are also provided.
    Type: Grant
    Filed: July 27, 2000
    Date of Patent: November 20, 2001
    Assignee: Maxygen, Inc.
    Inventors: Andreas Crameri, Willem P.C. Stemmer, Jeremy Minshull, Steven H. Bass, Mark Welch, Jon E. Ness, Claes Gustafsson, Phillip A. Patten
  • Integrated systems and methods for diversity generation and screening
    Publication number: 20010039014
    Abstract: Integrated systems and methods for diversity generation and screening are provided. The systems use common fluid and array handling components to provide nucleic acid diversification, transcription, translation, product screening and subsequent diversification reactions.
    Type: Application
    Filed: January 10, 2001
    Publication date: November 8, 2001
    Applicant: Maxygen, Inc.
    Inventors: Steven H. Bass, S. Christopher Davis, Phillip A. Patten, Matthew Tobin, Jeremy Minshull, Mark Welch, Claes Gustafsson, Brian Carr, Stephane Jenne, Sun Ai Raillard, Andreas Crameri, Willem P.C. Stemmer, Robin Emig, Pascal Longchamp, Stanley Goldman, Lorraine J. Giver, Joseph A. Affholter
  • Sorangium polyketide synthases and encoding DNA therefor
    Patent number: 6280999
    Abstract: Novel Sorangium polyketide synthases, and domains thereof, and polynucleotides encoding therefor. Additionally, chimeric polyketide synthases that include domains, or subsets of domains, patterned on said novel polyketide synthases. Methods to prepare polyketide combinatorial libraries are described, as are recombinant host cells in which polyketides are produced.
    Type: Grant
    Filed: August 31, 1998
    Date of Patent: August 28, 2001
    Assignee: Kosan Bioscience
    Inventors: Claes Gustafsson, Mary C. Betlach, Gary Ashley, Bryan Julien, Rainer Ziermann
  • Sorangium polyketide synthase
    Patent number: 6090601
    Abstract: Domains of epothilone polyketide synthase, and polynucleotides encoding therefor. Additionally, chimeric polyketide synthases that include domains, or subsets of domains, patterned on epothilone polyketide synthase. Methods to prepare epothilone in pharmaceutically useful quantitites are described, as are methods to prepare polyketide combinatorial libraries.
    Type: Grant
    Filed: January 23, 1998
    Date of Patent: July 18, 2000
    Assignee: Kosan Bioscience
    Inventors: Claes Gustafsson, Mary C. Betlach