Patents by Inventor Craig E. Masse

Craig E. Masse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TYK2 inhibitors and uses thereof
    Patent number: 10562907
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: February 18, 2020
    Assignee: Nimbus Lakshimi, Inc.
    Inventors: Craig E. Masse, Jeremy Robert Greenwood, Sayan Mondal, Scott D. Cowen, Thomas H. McLean
  • TYK2 inhibitors and uses thereof
    Patent number: 10562906
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: February 18, 2020
    Assignee: Nimbus Lakshimi, Inc.
    Inventors: Craig E. Masse, Jeremy Robert Greenwood, Sayan Mondal, Scott D. Cowen, Thomas H. McLean
  • TYK2 inhibitors and uses thereof
    Patent number: 10508120
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: December 17, 2019
    Assignee: Nimbus Lakshimi, Inc.
    Inventors: Craig E. Masse, Jeremy Robert Greenwood, Sayan Mondal, Scott D. Cowen, Thomas H. McLean
  • ACC inhibitors and uses thereof
    Patent number: 10472374
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: November 12, 2019
    Assignee: Gilead Apollo, LLC
    Inventors: Sathesh Bhat, Jeremy Robert Greenwood, Geraldine C. Harriman, James Harwood, Craig E. Masse
  • TYK2 INHIBITORS, USES, AND METHODS FOR PRODUCTION THEREOF
    Publication number: 20190337941
    Abstract: The present invention provides compounds useful as inhibitors of Tyrosine Kinase 2 (Tyk2), solid forms and compositions thereof, methods of producing the same, and methods of using the same in the treatment of Tyk2-mediated diseases.
    Type: Application
    Filed: May 21, 2019
    Publication date: November 7, 2019
    Inventors: Jeremy Robert Greenwood, Craig E. Masse, Jon P. Lawson, Jean-Baptiste Arlin, David Pearson, Jonathan James Loughrey
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20190284194
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Application
    Filed: April 30, 2019
    Publication date: September 19, 2019
    Inventors: Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit de Moradei, Craig E. Masse, Thomas H. McLean, Sayan Mondal
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20190256519
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Application
    Filed: April 12, 2019
    Publication date: August 22, 2019
    Inventors: Craig E. Masse, Jeremy Robert Greenwood, Sayan Mondal, Scott D. Cowen, Thomas H. McLean
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20190248797
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Application
    Filed: April 12, 2019
    Publication date: August 15, 2019
    Inventors: Craig E. Masse, Jeremy Robert Greenwood, Sayan Mondal, Scott D. Cowen, Thomas H. McLean
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20190248810
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Application
    Filed: February 8, 2019
    Publication date: August 15, 2019
    Inventors: Markus Dahlgren, Jeremy Robert Greenwood, Geraldine C. Harriman, Joshua Jahmil Kennedy-Smith, Craig E. Masse, Donna L. Romero, Mee Shelley, Ronald T. Wester
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20190241576
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Application
    Filed: April 12, 2019
    Publication date: August 8, 2019
    Inventors: Craig E. Masse, Jeremy Robert Greenwood, Sayan Mondal, Scott D. Cowen, Thomas H. McLean
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20190241575
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Application
    Filed: April 12, 2019
    Publication date: August 8, 2019
    Inventors: Craig E. Masse, Jeremy Robert Greenwood, Sayan Mondal, Scott D. Cowen, Thomas H. McLean
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20190241577
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Application
    Filed: April 12, 2019
    Publication date: August 8, 2019
    Inventors: Craig E. Masse, Jeremy Robert Greenwood, Sayan Mondal, Scott D. Cowen, Thomas H. McLean
  • TYK2 inhibitors, uses, and methods for production thereof
    Patent number: 10336752
    Abstract: The present invention provides compounds useful as inhibitors of Tyrosine Kinase 2 (Tyk2), solid forms and compositions thereof, methods of producing the same, and methods of using the same in the treatment of Tyk2-mediated diseases.
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: July 2, 2019
    Assignee: Nimbus Lakshmi, Inc.
    Inventors: Jeremy Robert Greenwood, Jon P. Lawson, Craig E. Masse, Jean-Baptiste Arlin, David Pearson, Jonathan James Loughrey
  • TYK2 inhibitors and uses thereof
    Patent number: 10323036
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: June 18, 2019
    Assignee: Nimbus Lakshmi, Inc.
    Inventors: Jeremy Robert Greenwood, Geraldine C. Harriman, Silvana Marcel Leit de Moradei, Craig E. Masse, Thomas H. McLean, Sayan Mondal
  • TYK2 inhibitors and uses thereof
    Patent number: 10253046
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Grant
    Filed: May 9, 2017
    Date of Patent: April 9, 2019
    Assignee: Nimbus Lakshmi
    Inventors: Markus Dahlgren, Jeremy Robert Greenwood, Geraldine C. Harriman, Joshua Jahmil Kennedy-Smith, Craig E. Masse, Donna L. Romero, Mee Shelley, Ronald T. Wester
  • ACC inhibitors and uses thereof
    Patent number: 10208063
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same. Specifically, bicyclic heteroaryl derivatives containing a imidazole, thiazole or oxazole fused to a pyridinone, pyrimidinone or pyrimidindione are provided. These compounds have therapeutic utility toward treating an ACC enzyme mediated disorder such as obesity in a subject, upon administration in an effective amount to said subject.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: February 19, 2019
    Assignee: GILEAD APOLLO, LLC
    Inventors: Jeremy Robert Greenwood, Geraldine C. Harriman, George Borg, Craig E. Masse
  • ACC inhibitors and uses thereof
    Patent number: 10208044
    Abstract: The present invention provides for compounds of formula I as acetyl-CoA carboxylase (ACC) inhibitors. The ACC inhibitors are useful for the prevention or treatment of metabolic syndrome, including obesity, dyslipidemia and hyperlipidemia in humans. The inhibitor compounds are also capable of inhibiting the ACC enzyme found in plants, parasites and bacteria.
    Type: Grant
    Filed: May 8, 2014
    Date of Patent: February 19, 2019
    Assignee: GILEAD APOLLO, LLC
    Inventors: Jeremy Robert Greenwood, Geraldine C. Harriman, George Borg, Craig E. Masse
  • TYK2 inhibitors and uses thereof
    Patent number: 10196390
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Grant
    Filed: March 13, 2017
    Date of Patent: February 5, 2019
    Assignee: Nimbus Lakshmi, Inc.
    Inventors: Craig E. Masse, Jeremy Robert Greenwood, Donna L. Romero, Geraldine C. Harriman, Ronald T. Wester, Mee Shelley, Joshua Jahmil Kennedy-Smith, Markus Dahlgren
  • TYK2 INHIBITORS AND USES THEREOF
    Publication number: 20190031664
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of TYK2, and the treatment of TYK2-mediated disorders.
    Type: Application
    Filed: July 26, 2018
    Publication date: January 31, 2019
    Inventors: Craig E. Masse, Jeremy Robert Greenwood, Sayan Mondal, Scott D. Cowen, Thomas H. McLean
  • ACC INHIBITORS AND USES THEREOF
    Publication number: 20190016732
    Abstract: The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
    Type: Application
    Filed: March 9, 2018
    Publication date: January 17, 2019
    Inventors: Sathesh Bhat, Jeremy Robert Greenwood, Geraldine C. Harriman, James Harwood, Craig E. Masse