Abstract: A biochemical substance analysis system (5) is used to detect biological characteristics of a sample in a flow cell (38), and includes a detection system (51), a scheduling system (53), a biochemical reaction system (55). and a control system (57). The scheduling system (53) is used to schedule the flow cell (38) at different sites, including sites in the detection system (51) and sites in the biochemical reaction system (55). The biochemical reaction system (55) is used to allow the sample to react in the flow cell (38). The detection system (51) is used to detect a signal from the reacted sample to obtain a signal representing the biological characteristics of the sample. The control system (57) is used to control the detection system (51), the scheduling system (53), and the biochemical reaction system (55) to cooperate. The disclosure improves automation degree and flux of the biochemical substance analysis.

Abstract: An adaptor includes a body defining a longitudinal axis, and a transverse axis that is normal to the longitudinal axis. The body also has a leading portion defining a lock receiving recess extending transversely at least partially through the leading portion. The leading portion defines at least one linear portion in the lock receiving recess that is configured to engage the power locking device.

Abstract: The invention is that of a removable shoe sole and a cycling shoe comprising said removable shoe sole, wherein the removable shoe sole may be affixed to the bottom of the cycling shoe to enable the wearer to gain traction on surfaces such as muddy ground surfaces. The removable shoe sole may be unitary or modular in design and comprises traction means such as anterior, medial and posterior traction means for enabling a cyclist to quickly affix the removable shoe sold to the bottom of his or her cycling shoes and walk or run across ground surfaces having low traction. The traction means may comprise ridges and valleys or similar means for engaging low-traction ground surfaces. The removable shoe sole may be made of durable material and affixed to a cycling shoe using off-the-shelf fasteners such as will be familiar to one of ordinary skill in the art.

Abstract: An adaptor includes a body defining a longitudinal axis, and a transverse axis that is normal to the longitudinal axis. The body also has a leading portion defining a lock receiving recess extending transversely at least partially through the leading portion. The leading portion defines at least one linear portion in the lock receiving recess that is configured to engage the power locking device.

Abstract: The present application describes novel antifouling coating compositions comprising carbon-based hydrolysable polymers of ethylenically unsaturated monomers of which some include cyclic carbonates or cyclic ethers, e.g. (2,2-dimethyl-1,3-dioxolan-4-yl)methyl (meth)acrylate (IPGA/IPGMA), isopropylidene glycerol ethoxylated acrylate (iPGEOA), isopropylidene glycerol ethoxylated methacrylate (iPGEOMA) and (2-oxo-1,3-dioxolan-4-yl)methyl (meth)acrylate (GCA/GCMA), and their use in antifouling coating compositions. Novel polymers are also described.

Abstract: A respiratory system is configured to pressurize and deliver a flow of respiratory gas to a patient's airways. The respiratory system includes a cushion configured to sealingly engage the patient's face and a blower mounted to the cushion and configured to pressurize a flow of respiratory gas. An interface structure is attached to an outlet of the blower and an aperture in the cushion. The interface structure forms a gas flow path between the cushion and the blower. The gas flow path is configured to deliver the pressurized respiratory gas from the blower through the aperture in the cushion. The gas flow path is also configured to vent exhaled gas from the aperture in the cushion to atmosphere. The respiratory system also includes headgear configured to support the cushion and the blower on the patient's face.

Abstract: A control system for a vehicle may include a plurality of vehicle subsystems associated with respective different dynamic vehicle control functions and a plurality of subsystem controllers associated with respective ones of the vehicle subsystems. The subsystem controllers may be configured to control actuators associated with the respective different dynamic vehicle control functions to change an operational state of components of the vehicle subsystems based on respective configuration settings. The system further includes an attribute configuration module operably coupled to the subsystem controllers. The attribute configuration module may include processing circuitry configured to save current configuration settings as a saved configuration responsive to a first actuation of a configuration mode actuator and, after an on/off cycle of the vehicle, instruct the subsystem controllers to implement the saved configuration responsive to a second actuation of the configuration mode actuator.

Abstract: Disclosed are processes for preparing [(3-hydroxypyridine-2-carbonyl)amino]-alkanoic acids, derivatives, inter alia, 5-aryl substituted and 5-heteroaryl substituted [(3-hydroxypyridine-2-carbonyl]amino}acetic acids. Further disclosed are methods for making prodrugs of [(3-hydroxypyridine-2-carbonyl)-amino]acetic acids, for example, [(3-hydroxypyridine-2-carbonyl]amino}acetic acid esters and {[3-hydroxypyridine-2-carbonyl]amino}acetic acid amides. The disclosed compounds are useful as prolyl hydroxylase inhibitors or for treating conditions wherein prolyl hydroxylase inhibition is desired.

Abstract: A respiratory system is configured to pressurize and deliver a flow of respiratory gas to a patient's airways. The respiratory system includes a cushion configured to sealingly engage the patient's face and a blower mounted to the cushion and configured to pressurize a flow of respiratory gas. An interface structure is attached to an outlet of the blower and an aperture in the cushion. The interface structure forms a gas flow path between the cushion and the blower. The gas flow path is configured to deliver the pressurized respiratory gas from the blower through the aperture in the cushion. The gas flow path is also configured to vent exhaled gas from the aperture in the cushion to atmosphere. The respiratory system also includes headgear configured to support the cushion and the blower on the patient's face.

Abstract: A cap (10) configured to interact with a spout (12), said cap (10) comprising: a proximal section (14), a distal section (16), a sidewall section (18) in between said proximal (14) and distal section (16); at least two rotating means (20) attached to said sidewall (18) wherein said rotating means (20) configured to be attached to a first tamper proof indicator; at least one cutting element (22) configured in the proximal section (14) of said cap (10) arranged to remove a second tamper proof indicator (24) provided in said spout (12); wherein said cap (10) is arranged such that said first tamper proof indicator is arranged to break or open before said second tamper proof indicator (24) of said spout (12) is removed when said cap (10) is being unscrewed from said spout (12).

Abstract: Methods, devices, and systems for laser eye surgery generally make use of a console that interchangeably accepts multiple types of eye treatment cassettes. The cassettes enable one or both of displacement-based or vacuum-based aspiration. The console and the cassette may communicate to establish the functionality of the installed cassette by utilizing a component indigenous to the operation of the cassette. A dual-mode cassette may include a separable holding tank for enabling vacuum-based aspiration. A displacement-based pump may be provided to drain the holding tank while the vacuum system continues to aspirate fluids. A vacuum sensor for controlling the flow of aspirated fluids may have three ports for communicating with a handpiece, a displacement-based pump, a vacuum-based pump, or an irrigation source. The handpiece may be vented during vacuum-based aspiration by opening a vent valve interposed between the handpiece and the vacuum source.

Abstract: An eye treatment system having a handpiece, a console, a cassette, and a pump formed by the engagement of the cassette with the console. The pump having a head having a plurality of projections disposed to rotate about an axis, a ramp disposed near the rotating projections, and a resilient channel configured to transfer fluid when engaged by the ramp and the plurality of projections. The ramp having an entrance, a central, and an exit portion. The entrance portion has an arcuate extent over which the projections close the channel as the head rotates. The central portion has an arcuate extent over which the channel is sealed by the projections as the head rotates. The exit portion has an arcuate extent over which the projections open the channel as the head rotates. The arcuate extent of the entrance portion is unequal to the arcuate extent of the exit portion.

Abstract: Methods, devices, and systems for laser eye surgery generally make use of a console that interchangeably accepts multiple types of eye treatment cassettes. The cassettes enable one or both of displacement-based or vacuum-based aspiration. The console and the cassette may communicate to establish the functionality of the installed cassette by utilizing a component indigenous to the operation of the cassette. A dual-mode cassette may include a separable holding tank for enabling vacuum-based aspiration. A displacement-based pump may be provided to drain the holding tank while the vacuum system continues to aspirate fluids. A vacuum sensor for controlling the flow of aspirated fluids may have three ports for communicating with a handpiece, a displacement-based pump, a vacuum-based pump, or an irrigation source. The handpiece may be vented during vacuum-based aspiration by opening a vent valve interposed between the handpiece and the vacuum source.

Abstract: Methods, devices, and systems for laser eye surgery generally make use of a console that interchangeably accepts multiple types of eye treatment cassettes. The cassettes enable one or both of displacement-based or vacuum-based aspiration. The console and the cassette may communicate to establish the functionality of the installed cassette by utilizing a component indigenous to the operation of the cassette. A dual-mode cassette may include a separable holding tank for enabling vacuum-based aspiration. A displacement-based pump may be provided to drain the holding tank while the vacuum system continues to aspirate fluids. A vacuum sensor for controlling the flow of aspirated fluids may have three ports for communicating with a handpiece, a displacement-based pump, a vacuum-based pump, or an irrigation source. The handpiece may be vented during vacuum-based aspiration by opening a vent valve interposed between the handpiece and the vacuum source.

Abstract: The present application describes novel antifouling coating compositions comprising carbon-based hydrolysable polymers of ethylenically unsaturated monomers of which some include cyclic carbonates or cyclic ethers, e.g. (2,2-dimethyl-1,3-dioxolan-4-yl)methyl (meth)acrylate (IPGA/IPGMA), isopropylidene glycerol ethoxylated acrylate (iPGEOA), isopropylidene glycerol N ethoxylated methacrylate (iPGEOMA) and (2-oxo-1,3-dioxolan-4-yl)methyl (meth)acrylate (GCA/GCMA), and their use in antifouling coating compositions. Novel polymers are also described.

Abstract: Disclosed are processes for preparing [(3-hydroxypyridine-2-carbonyl)amino]-alkanoic acids, derivatives, inter alia, 5-aryl substituted and 5-heteroaryl substituted [(3-hydroxypyridine-2-carbonyl]amino}acetic acids. Further disclosed are methods for making prodrugs of [(3-hydroxypyridine-2-carbonyl)-amino]acetic acids, for example, [(3-hydroxypyridine-2-carbonyl]amino}acetic acid esters and {[3-hydroxypyridine-2-carbonyl]amino}acetic acid amides. The disclosed compounds are useful as prolyl hydroxylase inhibitors or for treating conditions wherein prolyl hydroxylase inhibition is desired.

Abstract: Methods, devices, and systems for laser eye surgery generally make use of a console that interchangeably accepts multiple types of eye treatment cassettes. The cassettes enable one or both of displacement-based or vacuum-based aspiration. The console and the cassette may communicate to establish the functionality of the installed cassette by utilizing a component indigenous to the operation of the cassette. A dual-mode cassette may include a separable holding tank for enabling vacuum-based aspiration. A displacement-based pump may be provided to drain the holding tank while the vacuum system continues to aspirate fluids. A vacuum sensor for controlling the flow of aspirated fluids may have three ports for communicating with a handpiece, a displacement-based pump, a vacuum-based pump, or an irrigation source. The handpiece may be vented during vacuum-based aspiration by opening a vent valve interposed between the handpiece and the vacuum source.