Patents by Inventor Daniel A. Snyder

Daniel A. Snyder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INHIBITORS OF FATTY ACID AMIDE HYDROLASE
    Publication number: 20110224171
    Abstract: The present invention provide compounds, and pharmaceutical compositions thereof, encompassed by the formulae (I), (II) or (III). The present invention also provides methods for treating an FAAH mediated disease, disorder or condition by administering a therapeutically effective amount of a provided compound of the formulae (I), (II) or (III), or a pharmaceutical composition thereof, to a patient in need thereof. Additionally, the present invention provides methods for inhibiting FAAH in a patient by administering a therapeutically effective amount of a compound of the formulae (I), (II) or (III), or a pharmaceutical composition thereof, to a patient in need thereof.
    Type: Application
    Filed: March 16, 2011
    Publication date: September 15, 2011
    Inventors: Julian Adams, Mark L. Behnke, Alfredo C. Castro, Catherine A. Evans, Louis Grenier, Michael J. Grogan, Tao Liu, Daniel A. Snyder, Thomas T. Tibbitts
  • Compounds and Methods for Inhibiting the Interaction of BCL Proteins with Binding Partners
    Publication number: 20110213145
    Abstract: The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer.
    Type: Application
    Filed: April 19, 2011
    Publication date: September 1, 2011
    Applicant: Infinity Discovery, Inc.
    Inventors: Alfredo C. Castro, Kristopher M. Depew, Michael J. Grogan, Charles W. Johannes, Edward B. Holson, Brian T. Hopkins, Gregg F. Keaney, Nii O. Koney, Tao Liu, David A. Mann, Marta Nevalainen, Stephane Peluso, Lawrence B. Perez, Daniel A. Snyder, Thomas T. Tibbitts
  • INHIBITORS OF FATTY ACID AMIDE HYDROLASE
    Publication number: 20110172186
    Abstract: The present invention provides compounds, and pharmaceutically acceptable compositions thereof, encompassed by any of formulae (I), (II), (III), (IV), (V), or (VI), or subgenera thereof. The present invention also provides methods for treating an FAAH mediated disease, disorder or condition by administering a therapeutically effective amount of a compound or composition comprising a compound of any of formulae (I), (II), (III), (IV), (V), or (VI), or subgenera thereof, to a patient in need thereof. Additionally, the present invention provides methods for inhibiting FAAH by administering a therapeutically effective amount of a compound or composition comprising a compound of any of formulae (I), (II), (III), (IV), (V), or (VI), or subgenera thereof, to a patient in need thereof.
    Type: Application
    Filed: October 8, 2010
    Publication date: July 14, 2011
    Inventors: Mark L. Behnke, Alfredo C. Castro, Catherine A. Evans, Louis Grenier, Michael J. Grogan, Tao Liu, Daniel A. Snyder, Thomas T. Tibbitts
  • Compounds and Methods for Inhibiting the Interaction of BCL Proteins with Binding Partners
    Publication number: 20110160259
    Abstract: One aspect of the present invention relates to heterocyclic compounds that bind to bcl proteins and inhibit Bcl function. Another aspect of the present invention relates to compositions comprising a heterocyclic compound of the invention. The present invention provides methods for treating and modulating disorders associated with hyperproliferation, such as cancer.
    Type: Application
    Filed: November 30, 2010
    Publication date: June 30, 2011
    Applicant: Infinity Discovery, Inc.
    Inventors: Alfredo C. Castro, Edward B. Holson, Brian T. Hopkins, Nii O. Koney, Daniel A. Snyder, Thomas T. Tibbitts
  • Inhibitors of fatty acid amide hydrolase
    Patent number: 7947663
    Abstract: The present invention provide compounds, and pharmaceutical compositions thereof, encompassed by the formulae (I), (II) or (III). The present invention also provides methods for treating an FAAH mediated disease, disorder or condition by administering a therapeutically effective amount of a provided compound of the formulae (I), (II) or (III), or a pharmaceutical composition thereof, to a patient in need thereof. Additionally, the present invention provides methods for inhibiting FAAH in a patient by administering a therapeutically effective amount of a compound of the formulae (I), (II) or (III), or a pharmaceutical composition thereof, to a patient in need thereof.
    Type: Grant
    Filed: October 10, 2007
    Date of Patent: May 24, 2011
    Assignee: Infinity Pharmaceuticals, Inc.
    Inventors: Julian Adams, Mark L. Behnke, Alfredo C. Castro, Catherine A. Evans, Louis Grenier, Michael J. Grogan, Tao Liu, Daniel A. Snyder, Thomas T. Tibbitts
  • Solid-phase and solution-phase synthesis of glycosylphosphatidylinositol glycans
    Patent number: 7943594
    Abstract: One aspect of the present invention relates to solution-phase approaches to GPI synthesis. Another aspect of the present invention relates to key building blocks, and syntheses thereof, useful for GPI assembly. Yet another aspect of the invention relates to an automated method for the synthesis of GPIs and fragments thereof.
    Type: Grant
    Filed: July 10, 2003
    Date of Patent: May 17, 2011
    Assignee: Massachusetts Institute of Technology
    Inventors: Peter H. Seeberger, Michael C. Hewitt, Daniel A. Snyder
  • Compounds and methods for inhibiting the interaction of BCL proteins with binding partners
    Patent number: 7928244
    Abstract: The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer.
    Type: Grant
    Filed: August 21, 2007
    Date of Patent: April 19, 2011
    Assignee: Infinity Discovery, Inc.
    Inventors: Alfredo C. Castro, Kristopher M. Depew, Michael J. Grogan, Charles W. Johannes, Edward B. Holson, Brian T. Hopkins, Gregg F. Keaney, Nii O. Koney, Tao Liu, David A. Mann, Marta Nevalainen, Stephane Peluso, Lawrence B. Perez, Daniel A. Snyder, Thomas T. Tibbitts
  • ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE
    Publication number: 20110034437
    Abstract: The present invention provides isoxazoline FAAH inhibitors of the formula (I): or pharmaceutically acceptable forms thereof, wherein each of G, Ra, Rb, Rc, and Rd are as defined herein. The present invention also provides pharmaceutical compositions comprising a compound of formula (I), or a pharmaceutically acceptable form thereof, and a pharmaceutically acceptable excipient. The present invention also provides methods for treating an FAAH-mediated condition comprising administering a therapeutically effective amount of a compound of formula (I), or pharmaceutically acceptable form thereof, to a subject in need thereof.
    Type: Application
    Filed: May 18, 2010
    Publication date: February 10, 2011
    Applicant: Infinity Pharmaceuticals, Inc.
    Inventors: Mark L. Behnke, Alfredo C. Castro, Lawrence K. Chan, Catherine A. Evans, Louis Grenier, Michael J. Grogan, Yves Leblanc, Tao Liu, Stephane Peluso, Daniel A. Snyder, Thomas T. Tibbitts
  • ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE
    Publication number: 20110028478
    Abstract: The present invention provides isoxazoline FAAH inhibitors of the formula (I): or pharmaceutically acceptable forms thereof, wherein each of G, Ra, Rb, Rc, and Rd are as defined herein. The present invention also provides pharmaceutical compositions comprising a compound of formula (I), or a pharmaceutically acceptable form thereof, and a pharmaceutically acceptable excipient. The present invention also provides methods for treating an FAAH-mediated condition comprising administering a therapeutically effective amount of a compound of formula (I), or pharmaceutically acceptable form thereof, to a subject in need thereof.
    Type: Application
    Filed: May 18, 2010
    Publication date: February 3, 2011
    Applicant: Infinity Pharmaceuticals, Inc.
    Inventors: Mark L. Behnke, Alfredo C. Castro, Lawrence K. Chan, Catherine A. Evans, Louis Grenier, Michael J. Grogan, Yves Leblanc, Tao Liu, Stephane Peluso, Daniel A. Snyder, Thomas T. Tibbitts
  • ISOXAZOLINES AS INHIBITORS OF FATTY ACID AMIDE HYDROLASE
    Publication number: 20110028482
    Abstract: The present invention provides isoxazoline FAAH inhibitors of the formula (I): or pharmaceutically acceptable forms thereof, wherein each of G, Ra, Rb, Rc, and Rd are as defined herein. The present invention also provides pharmaceutical compositions comprising a compound of formula (I), or a pharmaceutically acceptable form thereof, and a pharmaceutically acceptable excipient. The present invention also provides methods for treating an FAAH-mediated condition comprising administering a therapeutically effective amount of a compound of formula (I), or pharmaceutically acceptable form thereof, to a subject in need thereof.
    Type: Application
    Filed: May 18, 2010
    Publication date: February 3, 2011
    Applicant: Infinity Pharmaceuticals, Inc.
    Inventors: Mark L. Behnke, Alfredo C. Castro, Lawrence K. Chan, Catherine A. Evans, Louis Grenier, Michael J. Grogan, Yves Leblanc, Tao Liu, Stephane Peluso, Daniel A. Snyder, Thomas T. Tibbitts
  • Compounds and methods for inhibiting the interaction of BCL proteins with binding partners
    Patent number: 7851637
    Abstract: One aspect of the present invention relates to heterocyclic compounds that bind to bcl proteins and inhibit Bcl function. Another aspect of the present invention relates to compositions comprising a heterocyclic compound of the invention. The present invention provides methods for treating and modulating disorders associated with hyperproliferation, such as cancer.
    Type: Grant
    Filed: June 17, 2005
    Date of Patent: December 14, 2010
    Assignee: Infinity Pharmaceuticals, Inc.
    Inventors: Alfredo C. Castro, Wei Deng, Kristopher M. Depew, Michael A. Foley, Christian C. Fritz, Asimina T. Georges Evangelinos, Michael J. Grogan, Nafeeza Hafeez, Edward B. Holson, Brian T. Hopkins, Nii O. Koney, Tao Liu, David A. Mann, Lisa A. Marcaurelle, Daniel A. Snyder, Dennis J. Underwood, Andrew A. Wylie, Lin-Chen Yu, Linping Zhang
  • Compounds and methods for inhibiting the interaction of BCL proteins with binding partners
    Patent number: 7842815
    Abstract: One aspect of the present invention relates to heterocyclic compounds that bind to bcl proteins and inhibit Bcl function. Another aspect of the present invention relates to compositions comprising a heterocyclic compound of the invention. The present invention provides methods for treating and modulating disorders associated with hyperproliferation, such as cancer.
    Type: Grant
    Filed: November 15, 2006
    Date of Patent: November 30, 2010
    Assignee: Infinity Pharmaceuticals, Inc.
    Inventors: Alfredo C. Castro, Edward B. Holson, Brian T. Hopkins, Nii O. Koney, Daniel A. Snyder, Thomas T. Tibbitts
  • Compounds and Methods for Inhibiting the Interaction of BCL Proteins with Binding Partners
    Publication number: 20100190791
    Abstract: The present invention relates to heterocyclic compounds that bind to Bcl proteins and inhibit Bcl function, compositions comprising such compounds, and methods for treating and modulating disorders associated with hyperproliferation, such as cancer.
    Type: Application
    Filed: April 2, 2010
    Publication date: July 29, 2010
    Applicant: INFINITY PHARMACEUTICALS, INC.
    Inventors: ALFREDO C. CASTRO, MICHAEL J. GROGAN, EDWARD B. HOLSON, BRIAN T. HOPKINS, NII O. KONEY, STEPHANE PELUSO, DANIEL A. SNYDER
  • Compounds and methods for inhibiting the interaction of BCL proteins with binding partners
    Patent number: 7745464
    Abstract: The present invention relates to heterocyclic compounds that bind to Bcl proteins and inhibit Bcl function, compositions comprising such compounds, and methods for treating and modulating disorders associated with hyperproliferation, such as cancer.
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: June 29, 2010
    Inventors: Alfredo C. Castro, Michael J. Grogan, Edward B. Holson, Brian T. Hopkins, Nii O. Koney, Stephane Peluso, Daniel A. Snyder
  • Techniques For Identifying And Comparing Virtual Machines In A Virtual Machine System
    Publication number: 20100083251
    Abstract: A technique for identifying virtual machines (VMs) in a VM system includes determining a configuration file location on a data store for the VM. A VM manager (for the VM) and an associated VM identification assigned to the VM (by the VM manager) are determined. A unique VM identification is then created based on the configuration file location on the data store, the VM manager, and the associated VM identification.
    Type: Application
    Filed: September 11, 2009
    Publication date: April 1, 2010
    Applicant: HYPER9, INC.
    Inventors: DAVE DENNIS MCCRORY, JAMES DANIEL SNYDER, II, WADE ALLEN REYNOLDS, BRIAN HAY MORTIMORE, JONATHAN MARK REEVE
  • INHIBITORS OF FATTY ACID AMIDE HYDROLASE
    Publication number: 20090099131
    Abstract: The present invention provide compounds, and pharmaceutical compositions thereof, encompassed by the formulae (I), (II) or (III). The present invention also provides methods for treating an FAAH mediated disease, disorder or condition by administering a therapeutically effective amount of a provided compound of the formulae (I), (II) or (III), or a pharmaceutical composition thereof, to a patient in need thereof. Additionally, the present invention provides methods for inhibiting FAAH in a patient by administering a therapeutically effective amount of a compound of the formulae (I), (II) or (III), or a pharmaceutical composition thereof, to a patient in need thereof.
    Type: Application
    Filed: October 10, 2007
    Publication date: April 16, 2009
    Applicant: Infinity Discovery, Inc.
    Inventors: Julian Adams, Mark L. Behnke, Alfredo C. Castro, Catherine A. Evans, Louis Grenier, Michael J. Grogan, Tao Liu, Daniel A. Snyder, Thomas T. Tibbitts
  • Anti-virus security information in an extensible markup language document
    Patent number: 7509573
    Abstract: Methods and systems are provided for allowing software applications capable of reading and saving Extensible Markup Language (XML) representations of documents to quickly and efficiently detect the presence of executable code contained in a given document being read or saved by the software applications. Examples of executable code include, but are not limited to macros, VBA macros, OLE code, OCX or ActiveX controls, embedded executable objects, and the like.
    Type: Grant
    Filed: February 17, 2004
    Date of Patent: March 24, 2009
    Assignee: Microsoft Corporation
    Inventors: Brian Jones, Marcin Sawicki, Robert Little, Daniel Snyder, Ambrose Treacy
  • Compounds and methods for inhibiting the interaction of BCL proteins with binding partners
    Publication number: 20080306127
    Abstract: One aspect of the present invention relates to heterocyclic compounds that bind to bcl proteins and inhibit Bcl function. Another aspect of the present invention relates to compositions comprising a heterocyclic compound of the invention. The present invention provides methods for treating and modulating disorders associated with hyperproliferation, such as cancer.
    Type: Application
    Filed: November 15, 2006
    Publication date: December 11, 2008
    Applicant: Infinity Pharmaceuticals, Inc.
    Inventors: Alfredo Castro, Edward Holson, Brian Hopkins, Nii Koney, Daniel Snyder, Thomas Tibbitts
  • METHOD AND APPARATUS FOR LOAD BALANCE SERVER MANAGEMENT
    Publication number: 20080271037
    Abstract: A computer implemented method, apparatus, and computer usable program code for balancing management loads. Loads are analyzed for a plurality of hardware control points to form an analysis in response to receiving a notification from a hardware control point indicating that a new manageable data processing system has been discovered. One of the plurality of hardware control points is selected using the analysis to form a selected hardware control point. The message is sent to the selected hardware control point to manage the new manageable data processing system, wherein the selected hardware control point manages the new manageable data processing system.
    Type: Application
    Filed: April 27, 2007
    Publication date: October 30, 2008
    Inventors: Antonio Abbondanzio, Shamsundar Ashok, NicoleLyne Jones, Dennis Duane Jurgensen, Rolf Kocheisen, Yan Schloem Koyfman, Sherry Michelle Pitz, Peter Andrew Richman, Devon Daniel Snyder, William John Vanca, Philip Kincheloe Warren, Robert Edward Warren
  • Compounds and Methods for Inhibiting the Interaction of BCL Proteins with Binding Partners
    Publication number: 20080114167
    Abstract: The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer.
    Type: Application
    Filed: August 21, 2007
    Publication date: May 15, 2008
    Applicant: Infinity Discovery, Inc.
    Inventors: Alfredo CASTRO, Kristopher DEPEW, Michael GROGAN, Charles JOHANNES, Edward HOLSON, Brian HOPKINS, Gregg KEANEY, Nii KONEY, Tao LIU, David MANN, Marta NEVALAINEN, Stephane PELUSO, Lawrence PEREZ, Daniel SNYDER, Thomas TIBBITTS