Abstract: Disclosed are a system and method for evaluating a tissue sample that has been removed from a subject. Movement of fluid through the tissue sample is monitored by measuring time of flight of acoustic waves passed through the tissue sample. A system for performing the method can include a transmitter that outputs the energy and a receiver configured to detect the transmitted energy. Using the disclosed method and system, an optimized protocol for ensuring adequate distribution of the fluid throughout a variety of tissue types and/or sample sizes can be developed and utilized.

Abstract: In order to provide a simplified inspection of an aircraft for the pilot, an aircraft inspection system is provided which includes at least one movable inspection unit, a position detection arrangement, and at least one data transfer interface. The at least one moveable inspection unit is moveable relative to an aircraft to be inspected. The at least one movable inspection unit includes at least one sensor for detecting a characteristic value, for verifying a characteristic and/or for determining a defect of an aircraft. The movable inspection unit is configured to generate monitoring data. When a defect or a characteristic value is detected, the position detection arrangement detects position data of the movable inspection unit in relation to the aircraft to be inspected, and assigns the position data to the monitoring data. The data transfer interface provides the position data with the assigned monitoring data as inspection data.

Abstract: The subject disclosure presents systems and computer-implemented methods for evaluating a tissue sample that has been removed from a subject. A change in speed of the energy traveling through the sample is evaluated to monitor changes in the biological sample during processing. The rate of change in the speed of the energy is correlated with the extent of diffusion. A system for performing the method can include a transmitter that outputs the energy and a receiver configured to detect the transmitted energy. A time-of-flight of acoustic waves and rate of change thereof is monitored to determine an optimal time for soaking the tissue sample in a fixative.

Abstract: The subject disclosure presents systems and computer-implemented methods for calculating the diffusivity constant of a sample using acoustic time-of-flight (TOF) based information correlated with a diffusion model to reconstruct a sample's diffusivity coefficient. Operations disclosed herein such as acoustically determining the phase differential accumulated through passive fluid exchange (i.e. diffusion) based on the geometry of the tissue sample, modeling the impact of the diffusion on the TOF, and using a post-processing algorithm to correlate the results to determine the diffusivity constant, are enabled by monitoring the changes in the speed of sound caused by penetration of fixative such as formalin into several tissue samples. A tissue preparation system may be adapted to monitor said diffusion of a tissue sample and determine an optimal processing workflow.

Abstract: The subject disclosure presents systems and computer-implemented methods for determining an acoustic time-of-flight (TOF) of sound waves through a sample material with greater accuracy and in a more repeatable fashion, by invoking one or more of an envelope generation for an error function, fitting a non-linear curve to an ultrasound frequency sweep, or performing a clustered piece-wise linear regression on individual linear parts of the ultrasonic frequency sweep. The systems and methods are useful for, among other things, monitoring diffusion of fluids through porous materials, such as tissue samples.

Abstract: The present disclosure relates to use of high-concentration aldehyde-based fixatives to fix tissue samples. Aldehyde concentrations are selected that significantly increase rate of diffusion of the fixative solution into the tissue. When combined in the cold-temperature step of a two-temperature fixation, a substantial improvement in the preservation of post-translationally modified proteins is achieved.

Abstract: A testing arrangement serves for controlling the manufacturing of a fiber reinforced component. The testing arrangement includes an inspection device with a sensor system, with the inspection device being configured to move on and/or above one or more material layer(s) and/or a surface of the component and to examine the material layer(s) or the surface with the sensor system. A device serves for automated manufacturing of a fiber reinforced plastic laminate. The device includes a forming tool, a laying head for automated laying of material layers in the forming tool as well as a testing arrangement.

Abstract: A mechanism for declarative service domain federation uses a declarative approach to both the visibility aspect and the management aspect of service domain federation. Instead of manually exporting services, that is, selecting individual services from source domains to be visible in the target domain, using the present system, a federation architect uses a federation console to specify federation intent. The federation intent may include federation rule, query-based service group, and quality-of-service (QoS) policy. Based on the declared federation intent, a planning engine resolves the individual services based on the group query, generates the service visibility configuration, and creates the necessary service proxies and/or mediation objects to satisfy the goal. At runtime, a service monitor collects the performance metrics of federated services and dynamically adjusts the mediation/proxy configurations to maintain the QoS objectives specified by the federation architect.

Abstract: A mechanism for declarative service domain federation uses a declarative approach to both the visibility aspect and the management aspect of service domain federation. Instead of manually exporting services, that is, selecting individual services from source domains to be visible in the target domain, using the present system, a federation architect uses a federation console to specify federation intent. The federation intent may include federation rule, query-based service group, and quality-of-service (QoS) policy. Based on the declared federation intent, a planning engine resolves the individual services based on the group query, generates the service visibility configuration, and creates the necessary service proxies and/or mediation objects to satisfy the goal. At runtime, a service monitor collects the performance metrics of federated services and dynamically adjusts the mediation/proxy configurations to maintain the QoS objectives specified by the federation architect.

Abstract: Methods of treating individuals identified as having cancer using ATP citrate lyase inhibitor and/or tricarboxylate transporter inhibitor are disclosed. Methods of inducing apoptosis in cancer cells using an ATP citrate lyase inhibitor and/or tri-carboxylate transporter inhibitor are disclosed. of treating an individual who has cancer comprising the steps of identifying the cancer as having a high rate of aerobic glycolysis, and administering an ATP citrate lyase inhibitor and/or tricarboxylate transporter inhibitor are disclosed. Methods of treating individuals who have cancer using compounds that inhibit the expression of ATP citrate lyase or tricarboxylate transporter are disclosed. Methods of identifying a compound with anticancer activity are disclosed.

Abstract: Apportioning apparatus for apportioning moist cut or ground tobacco material with moisture content of at least 35%. Apportioning apparatus includes metering unit; weighing cell; and control unit coupled via a first data link to the metering unit and via a second data link to weighing cell. Metering unit is configured to add a predetermined portion of tobacco material to a receptacle, and metering unit and weighing cell are arranged relative to each other such that, while receptacle is being filled by metering unit, a weight of the added tobacco material is detected by weighing cell, and data relative to the detected weight is communicated via first data link to the control unit. Control unit is configured to control metering unit via second data link on the basis of received data relative to weight of added tobacco material such that a predetermined portion of tobacco material is added to receptacle.

Abstract: A method for accurately acquiring multiple analog input signals that are converted using a plurality of A/D converters into corresponding digital single measured values. A first measurement averaging cycle having a predetermined total number of measuring intervals is predetermined by a higher-order control unit. First and second input signals are acquired by first and second A/D converters in a first and second number of measuring intervals, the second number being smaller than the first number. The first and second input signals are averaged to form first and second measured values, respectively. The first input signal is acquired by the second A/D converter in a third number of measuring intervals as at least one further single measured value.

Abstract: A system for providing flight accident insurance at low price and fixed coverage comprises means for limiting the number of policies that can be sold on any given flight to not more than a predetermined number. The predetermined number may be 20. The system comprises an input device for receiving information from a traveler and an output device for providing an insurance quote to said traveler.

Abstract: A system for providing flight accident insurance at low price and fixed coverage comprises means for limiting the number of policies that can be sold on any given flight to not more than a predetermined number. The predetermined number may be 20. The system comprises an input device for receiving information from a traveler and an output device for providing an insurance quote to said traveler.

Abstract: A mechanism for declarative service domain federation uses a declarative approach to both the visibility aspect and the management aspect of service domain federation. Instead of manually exporting services, that is, selecting individual services from source domains to be visible in the target domain, using the present system, a federation architect uses a federation console to specify federation intent. The federation intent may include federation rule, query-based service group, and quality-of-service (QoS) policy. Based on the declared federation intent, a planning engine resolves the individual services based on the group query, generates the service visibility configuration, and creates the necessary service proxies and/or mediation objects to satisfy the goal. At runtime, a service monitor collects the performance metrics of federated services and dynamically adjusts the mediation/proxy configurations to maintain the QoS objectives specified by the federation architect.

Abstract: A method, device, and computer program product are provided for automatically generating connectivity configuration between domains by a device. A rule is received by the device. The rule is read by the device to determine a first domain invoking a service, a second domain having the service, and connectivity requirements for the first and second domains. A first proxy and a second proxy are automatically determined to fulfill the rule by the device. The first proxy is automatically assigned to the first domain and the second proxy is automatically assigned to the second domain.

Abstract: A system for providing flight accident insurance at low price and fixed coverage comprises means for limiting the number of policies that can be sold on any given flight to not more than a predetermined number. The predetermined number may be 20. The premium for the insurance is a function of the GDP of the country in which the airline operating said flight is domiciled such that said premium is a decreasing function of said GDP.

Abstract: A method, device, and computer program product are provided for automatically generating connectivity configuration between domains by a device. A rule is received by the device. The rule is read by the device to determine a first domain invoking a service, a second domain having the service, and connectivity requirements for the first and second domains. A first proxy and a second proxy are automatically determined to fulfill the rule by the device. The first proxy is automatically assigned to the first domain and the second proxy is automatically assigned to the second domain.

Abstract: A computer-implemented data processing system, computer-implemented method and computer program product for processing data. The system includes: a scheduler; a processor system; and at least one producer for executing a task. The scheduler is operable to allocate to the producer with respect to a scheme, a processing time of a processing resource of the processor system. The producer is operable to execute the task using said processor system during the allocated processing time.

Abstract: A method for securely acquiring multiple analog input signals that are converted using a plurality of A/D converters into corresponding digital single measured values. A first measurement averaging cycle having a predetermined total number of measuring intervals is predetermined by a higher-order control unit. First and second input signals are acquired by first and second A/D converters in a first and second number of measuring intervals, the second number being smaller than the first number. The first and second input signals are averaged to form first and second measured values, respectively. The first input signal is acquired by the second A/D converter in a third number of measuring intervals as at least one further single measured value.