Abstract: A perturbation radio frequency (RF) signal generator is provided which generates a perturbed RF output signal to cause a signal classification change by an RF signal classifier. The perturbation RF signal generator may include a quantum computing circuit configured to perform quantum subset summing; and a processor. The processor may be configured to generate a game theory reward matrix for a plurality of different deep learning signal perturbation models, cooperate with the quantum computing circuit to perform quantum subset summing of the game theory reward matrix, select a deep learning signal perturbation model from the plurality thereof based upon the quantum subset summing of the game theory reward matrix, and generate the perturbed RF output signal based upon the selected deep learning signal perturbation model to cause the signal classification change in the RF signal classifier.

Abstract: A computer-implemented method of classifying an image using a quantum trained vision system. The method comprises enhancing contrast of the image and applying dimension reduction to the contrast-enhance image. The enhanced contrast and dimensionally reduced image is passed to a quantum trained vision system and a result is generated from the quantum trained vision system. The result could be a simply yes/no or true/false binary result to see whether the image fell into one of several predefined classes. Alternatively, the result could be an indication of an object in the image.

Abstract: Compositions and methods are provided for genome modification of a target sequence in the genome of a plant or plant cell, without incorporating a selectable transgene marker. The methods and compositions employ a guide polynucleotide/Cas endonuclease system to provide an effective system for modifying or altering target sites within the genome of a plant, plant cell or seed, without incorporating a selectable transgene marker. Once a genomic target site is identified, a variety of methods can be employed to further modify the target sites such that they contain a variety of polynucleotides of interest. Breeding methods and methods for selecting plants utilizing a guide polynucleotide/Cas endonuclease system are also disclosed. Compositions and methods are also provided for editing a nucleotide sequence in the genome of a cell, without incorporating a selectable transgene marker.

Abstract: This invention pertains to biotechnology, more specifically to the field of human health. This document describes in particular conjugates of the SARS-CoV-2 receptor binding domain covalently conjugated to a carrier protein, the method used to obtain them, and the vaccine compositions that contain them. The vaccine compositions described in this invention are useful for the prevention of the SARS-CoV-2 infection as they induce a strong response of neutralizing antibodies.

Abstract: Disclosed herein are agricultural compositions comprising plant messenger packs (PMPs), methods for using the same, and methods and related bioreactors for manufacturing PMPs.

Abstract: A magnet assembly for a debris collection tool includes first and second annular end bands, between which is disposed an annular arrangement of magnets. The magnet assembly includes a plurality of bridges, each bridge disposed between the first and second annular end bands and between circumferentially adjacent magnets of the annular arrangement of magnets. The first and second annular end bands are substantially of a non-magnetic material, and the bridges are substantially of a magnetic material.

Abstract: Method for generating and controlling complex strain patterns on biological materials comprising the steps of providing a magnetic stimulation device and a magneto-responsive substrate; culturing biological material in the substrate; determining the position of the magnetic stimulation device for obtaining a defined strain pattern on the biological material; placing the magnets in the position determined; and activating a magnetic stimulation device to generate a complex strain pattern in the magneto-responsive substrate and consequently in the biological material; and magneto-mechanical stimulation system comprising a magneto-responsive substrate configured to hold biological material; a holder for placing the magneto-responsive substrate; a magnetic stimulation device configured to generate a complex strain pattern on the biological material by generating a magnetic field which acts over the magneto-responsive substrate; a computing module; an imaging module for long-term monitoring; and an interface module

Abstract: A clot mobilizer device for extraction of an occlusion from a blood vessel is provided, which comprises a working portion including a plurality of crowns of cells. Each cell comprises an open area bordered by struts. A distal end of each cell in a first crown is contiguous with a proximal end of a corresponding cell in a third crown, and a distal end of each cell in a second crown is contiguous with a proximal end of a corresponding cell in a fourth crown. The second crown is disposed distal to the first crown and proximal to the third crown, and the fourth crown is disposed distal to the third crown. The plurality of crowns of cells define a tubular-shaped section forming a cylindrically closed structure. The clot mobilizer also comprises a tapered portion extending proximally from the proximal end of the working portion and comprising a plurality of struts.

Abstract: An elongated device with an improved attachment of its elements is provided. The device comprises a working element comprising a first connection portion extending proximally, the first connection portion having a first attachment surface; a pusher comprising a second connection portion extending distally, the second connection portion having a second attachment surface facing and extending longitudinally aligned to the first attachment surface to define an overlapping portion and to define first and second seams extending longitudinally along first and second lateral extents of the overlapping portion; a first weld attaching the first and second connection portions, extending from the first seam toward the second seam; and a second weld attaching the first and second connection portions, extending from the second seam toward the first seam. A method for connecting a working element to a pusher is also provided.

Abstract: Disclosed herein are microfluidic devices and methods to deliver concentration gradients to biological material such as oocytes and embryos for the purpose of cryopreparation, cryopreservation, or thawing. Cryopreservation methods, such as vitrification, involve the use of cryoprotectants to reduce formation of damaging ice crystals in cells during freezing. Microfluidic devices and methods described herein improve cell viability and efficiency during handling and cryopreservation of biological materials.

Abstract: A digital radio OFDM modulator and demodulator provide an efficient mode and a backwards-compatible mode to work with IEEE 802.15.4g or a similar standard. In backwards-compatible mode, they use a single method for error encoding physical header and payload transmit data, and a single method for detecting and correcting errors in physical header and payload receive data. In efficient mode, they use two different methods. The payload is BCH-LDPC encoded. They may also use mapping constellations that are not available in IEEE 802.15.4g, including 64-QAM, 256-QAM, and APSK. To ensure that physical header data can be received more robustly than payload data, they use frequency diversity of the physical header data, and selection maximal ratio combining (SMRC) in the demodulator to reduce the bit error rate (BER) at a low cost.

Abstract: A method and computer programmes for the management of vehicle fleets are proposed. The method comprises the obtaining of data concerning the state and the operation of each of a plurality of vehicles of a particular type in a vehicle fleet; detecting an anomalous average fuel consumption over a certain period in at least one first vehicle of said vehicle fleet on the basis of analysis of the data received; determining and accounting for the cause of said anomalous average fuel consumption detected by means of the implementation of an explainable artificial intelligence algorithm that takes into account different parameters of the first vehicle, including parameters concerning: the driving behaviour of the first vehicle over a set period of time, the state of the first vehicle and a number of meteorological and environmental elements, and deducing the influence of each of the parameters.

Abstract: A method and computer programmes for the management of vehicle fleets are proposed. The method comprises the obtaining of data concerning the state and the operation of each of a plurality of vehicles of a particular type in a vehicle fleet; detecting an anomalous average fuel consumption over a certain period in at least one first vehicle of said vehicle fleet on the basis of analysis of the data received; determining and accounting for the cause of said anomalous average fuel consumption detected by means of the implementation of an explainable artificial intelligence algorithm that takes into account different parameters of the first vehicle, including parameters concerning: the driving behaviour of the first vehicle over a set period of time, the state of the first vehicle, and a number of meteorological and environmental elements.

Abstract: An article of headgear to be worn on the head of a user includes a first portion to encompass at least a portion of the head of the user and a visor extending forward from the first portion. The visor includes a laterally extending opening therein to receive a personal communication device including a camera such that a lens of the camera is positioned below the lower surface of the visor.

Abstract: A method for identifying a quantitative trait locus associated with desirable nutritional traits in canola includes: analyzing a population of canola plants or germplasm for desirable nutritional traits; determining the genotype of the canola plants or germplasm using at least one marker selected from the group consisting of SEQ ID NO:1 through SEQ ID NO:111; mapping the canola plants or germplasm for the presence of a quantitative trait locus (QTL) associated with the markers; and associating the QTL with the desirable nutritional trait. An isolated and/or recombinant nucleic acid includes a sequence associated with a quantitative trait locus (QTL), wherein the QTL is associated with a desirable nutritional trait in a canola plant or germplasm and wherein the QTL is further associated with at least one marker selected from the group consisting of SEQ ID NO:1 through SEQ ID NO:111.

Abstract: A system and method for maintenance and supplying of a fleet of multifunction peripheral devices includes two or more networked devices including a decision engine. Devices discover one another and one device is designated as a server. The server creates a virtual lobby accessible by other devices and its decision engine is enabled. The server invites other devices into its virtual lobby, and these devices join the lobby in response. Devices provide their device state information to the lobby. The enabled decision engine generates recommendations for consumable replenishment, device servicing or device configuration, relaying the recommendations to a system administrator's tablet or smartphone. The administrator may accept, reject, modify or implement received suggestions. Consumable supplies or servicing recommendations can be done automatically if enabled. Administrator actions are fed back to the server for machine learning to improve future suggestions.

Abstract: Disclosed herein are microfluidic devices and methods to deliver concentration gradients to biological material such as oocytes and embryos for the purpose of cryopreparation, cryopreservation, or thawing. Cryopreservation methods, such as vitrification, involve the use of cryoprotectants to reduce formation of damaging ice crystals in cells during freezing. Microfluidic devices and methods described herein improve cell viability and efficiency during handling and cryopreservation of biological materials.

Abstract: A method for providing a yaw angle (105a) between a first vehicle (110) coupled to a second vehicle (100), comprises: receiving an image of the first vehicle from a camera (101) mounted on the second vehicle; performing (210) a polar transformation on the image to form a polar image (400) in a polar space having an origin corresponding to a location of a pivot point (303) of the coupling (302) to the second vehicle in the received image coordinate space; estimating (230) an optical coupling angle by analysing the content of the polar image; receiving a signal from an odometer (102) mounted on the first or second vehicle; estimating a kinematic coupling angle from the signal and a kinematic model of the first vehicle and the coupled second vehicle; and combining the estimated optical coupling angle and the estimated kinematic coupling angle to provide the coupling angle.

Abstract: Phytosphingosine derivatives suitable as adjuvants in immune stimulation, pharmaceutical compositions comprising such compounds and the medical use of the compounds and/or compositions in therapeutic or prophylactic methods of immune stimulation in a subject, and for use in the treatment of a disease, for which stimulation of an immune response in a subject produces a therapeutic benefit. The phytosphingosine derivative may also be used as adjuvants in vaccinating a subject. The phytosphingosine derivative may also be used in stimulating antibody production, stimulating an immune response against infection, stimulating an immune response against a cancer, or preventing and/or treating septic shock. Methods for the manufacture of the derivatives comprising an Ugi-4-component reaction (Ugi-4CR) is also disclosed.

Abstract: A package that includes a substrate having a first surface; a solder resist layer coupled to the first surface of the substrate; a device located over the solder resist layer such that a portion of the device touches the solder resist layer; and an encapsulation layer located over the solder resist layer such that the encapsulation layer encapsulates the device. The solder resist layer is configured as a seating plane for the device. The device is located over the solder resist layer such that a surface of the device facing the substrate is approximately parallel to the first surface of the substrate. The solder resist layer includes at least one notch. The device is located over the solder resist layer such that at least one corner of the device touches the at least one notch.