Patents by Inventor Dapeng Sun

Dapeng Sun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High Fidelity Restriction Endonucleases
    Publication number: 20110151450
    Abstract: Methods and compositions are provided for engineering mutant enzymes with reduced star activity where the mutant enzymes have a fidelity index (FI) in a specified buffer that is greater than the FI of the non-mutated enzyme in the same buffer.
    Type: Application
    Filed: February 7, 2011
    Publication date: June 23, 2011
    Applicant: NEW ENGLAND BIOLABS, INC.
    Inventors: Zhenyu Zhu, Aine Quimby, Shengxi Guan, Dapeng Sun, Yishu Huang, Xuhui Lai, Siu-hong Chan, Xianghui Li, Shuang-Yong Xu, Chunhua Zhang
  • High Fidelity Restriction Endonucleases
    Publication number: 20090029376
    Abstract: Compositions and methods are provided for enzymes with altered properties that involve a systematic approach to mutagenesis and a screening assay that permits selection of the desired proteins. Embodiments of the method are particularly suited for modifying specific properties of restriction endonucleases such as star activity. The compositions include restriction endonucleases with reduced star activity as defined by an overall fidelity index improvement factor.
    Type: Application
    Filed: July 14, 2008
    Publication date: January 29, 2009
    Applicant: New England Biolabs, Inc.
    Inventors: Zhenyu Zhu, Aine Blanchard, Shuang-Yong Xu, Shengxi Guan, Hua Wei, Penghua Zhang, Dapeng Sun, Siu-Hong Chan