Abstract: This document describes techniques, apparatuses, and systems for a grid-based road model with multiple layers. An example road-perception system generates a roadway grid representation that includes multiple cells. The road-perception system uses data from multiple information sources to generate a road model that includes multiple layers. Each layer represents a roadway attribute of each cell in the grid and includes one or more layer hypotheses. In this way, the described techniques and systems can provide an accurate and reliable road model and quantify uncertainty therein.

Abstract: An engine braking system includes engine braking actuators for adjusting exhaust valve timings to engine braking timings in a cylinder-number braking mode. The system further includes an engine braking controller coupled to a control switch that produces a request indicating a requested cylinder-number braking mode. The engine braking controller is structured to transition exhaust valves to the engine braking timings, determine a control term to adjust intake air pressure for varying a braking power of the engine, and to adjust geometry of an exhaust turbine based on the control term. An adjusted speed of a compressor rotated by the exhaust turbine provides a change to intake air pressure that adjusts the braking power of the engine. Different levels of braking power are provided within different cylinder-number braking modes.

Abstract: Punch assembly that enable selective securement and release of punch tips to a punch body (or holder) of the assemblies, wherein various retain/release systems can be used with the punch body, specifically relative to triggering mechanisms of such systems and their functioning and use with ancillary components relative to securing and releasing the punch tip, without adversely affecting long-term efficiency and effectiveness of the assemblies.

Abstract: The invention provides diagnostic and therapeutic targets for pulmonary disease, in particular, fibrotic lung disease. The inventors have found that a genetic variant MUC5B gene is associated with increased expression of the gene, increased risk of developing a pulmonary disease, and an improved prognosis and survival among those developing the pulmonary disease.

Abstract: This document describes techniques, apparatuses, and systems for a grid-based road model with multiple layers. An example road-perception system generates a roadway grid representation that includes multiple cells. The road-perception system uses data from multiple information sources to generate a road model that includes multiple layers. Each layer represents a roadway attribute of each cell in the grid and includes one or more layer hypotheses. In this way, the described techniques and systems can provide an accurate and reliable road model and quantify uncertainty therein.

Abstract: A gas monitor apparatus includes a sorbent material that adsorbs a target gas based on a concentration of the target gas in a monitored environment and a reference material that does not respond to the target gas. The gas monitor also includes a first thermistor disposed within the sorbent material and a second thermistor disposed within the reference material, the first thermistor to provide a first indication of a first temperature of the sorbent material and the second thermistor to provide a second indication of a second temperature of the reference material. A processing device determines a concentration of the target gas based at least in part on a differential measurement between the first temperature and the second temperature.

Abstract: Exemplary embodiments of the present disclosure can provide for a transparent panel that can have a featured image which can be surrounded by a pattern of repeating designs on a first side of the panel. A vinyl layer can be provided on the entire first side of the panel to assist in the featured image and repeating designs to be viewable on the second side of the panel (opposite of the first side). On the second opposite side of the panel, an area of the panel where the pattern of designs is visible is provided with a series of lens that can overly the repeating designs. In some exemplary embodiments, the lenses can project enlarged representations of the underlying repeating designs that appear to the eye as occupying a different plane than the featured image, creating a sense of depth within the image.

Abstract: An incorrect copy of a record of data can be prevented from being transmitted to a distributed ledger system. A first file can be received and can include information, in audio or video form, with a description of a subject matter of the record of data and with an authorization to transmit the copy to the distributed ledger system. The first file can be sent to a device. A second file can be received from the device and can include information that confirms that the description of the subject matter, included in the first file, is correct, and that confirms that an entity, which controlled production of the first file, has permission to authorize causing the copy to be transmitted to the distributed ledger system. The correct copy can be caused, based on a receipt of the first and the second files, to be transmitted to the distributed ledger system.

Abstract: Disclosed herein are biomarkers related to preclinical pulmonary fibrosis and methods of identifying the same. In embodiments, the biomarkers are proteins. In embodiments, the biomarkers are transcripts.

Abstract: An incorrect copy of a record of data can be prevented from being transmitted to a distributed ledger system. A first file can be received and can include information, in audio or video form, with a description of a subject matter of the record of data and with an authorization to transmit the copy to the distributed ledger system. The first file can be sent to a device. A second file can be received from the device and can include information that confirms that the description of the subject matter, included in the first file, is correct, and that confirms that an entity, which controlled production of the first file, has permission to authorize causing the copy to be transmitted to the distributed ledger system. The correct copy can be caused, based on a receipt of the first and the second files, to be transmitted to the distributed ledger system.

Abstract: This document describes techniques, apparatuses, and systems for a grid-based road model with multiple layers. An example road-perception system generates a roadway grid representation that includes multiple cells. The road-perception system uses data from multiple information sources to generate a road model that includes multiple layers. Each layer represents a roadway attribute of each cell in the grid and includes one or more layer hypotheses. In this way, the described techniques and systems can provide an accurate and reliable road model and quantify uncertainty therein.

Abstract: Various designs of die shoe assemblies are provided, each assembly configured to adjust vertical positioning of a die platform within the assembly, in order to correspondingly adjust vertical positioning of a die used with the assembly. The assemblies address limitations often associated with conventional die shoes designed to be used with shims. The assemblies use various methods and corresponding mechanisms to make the adjustment a time efficient process, while in so doing also enabling the desired extent of adjustment to be effectively and accurately provided.

Abstract: This document describes techniques and systems to make determinations of lane-type and roadway hypotheses in a road model. The road-perception system can fuse various forms of evidence to determine lane-type hypotheses and respective belief masses associated with the lane-type hypotheses. The road-perception system the computes, using the belief masses, a belief parameter and a plausibility parameter associated with the lane-type hypotheses. One or more roadway hypotheses are then determined using the lane-type hypotheses. The road-perception system then uses the respective belief parameter and plausibility parameter associated with the lane-type hypotheses to compute a belief parameter and a plausibility parameter associated with the roadway hypotheses. In this way, the described techniques and systems can provide an accurate and reliable road model with quantified uncertainty.

Abstract: An incorrect transmission, of a record of data to a distributed ledger system, can be prevented. A first signal can be received. The first signal can include a first instruction to cause the record to be transmitted to the system. One or more items of information in the record can be determined. A delay of time to be elapsed, before a transmission of the record to the system, can be set in response to a receipt of the first signal and a determination of the one or more items. The transmission of the record to the system can be caused to occur after the delay has elapsed. The transmission of the record to the system can be prevented in response to a receipt of a second signal before the delay has elapsed. The second signal can include a second instruction that supersedes the first instruction.

Abstract: An engine braking system includes engine braking actuators for adjusting exhaust valve timings to engine braking timings in a cylinder-number braking mode. The system further includes an engine braking controller coupled to a control switch that produces a request indicating a requested cylinder-number braking mode. The engine braking controller is structured to transition exhaust valves to the engine braking timings, determine a control term to adjust intake air pressure for varying a braking power of the engine, and to adjust geometry of an exhaust turbine based on the control term. An adjusted speed of a compressor rotated by the exhaust turbine provides a change to intake air pressure that adjusts the braking power of the engine. Different levels of braking power are provided within different cylinder-number braking modes.

Abstract: A method of screening a test compound, e.g., a fibrosis or IPF inhibitor, for induction of an unjammed-to-jammed transition (UJT) in fibrotic primary human bronchial epithelial cells (HBECs) isolated from a subject with a fibrotic lung disease includes culturing the fibrotic primary HBECs at an air-liquid interface for a time sufficient to provide a differentiated pseudostratified epithelium contacting the cultured cells with the test compound; and monitoring the motility of the cultured cells to identify the cultured cells as moving or stationary; wherein stationary cultured cells indicate that the test compound induces the UJT. Also included are methods of identifying lung fibrosis biomarkers.

Abstract: The present disclosure is directed to methods and/or uses of oligonucleotide conjugates for assays and flow cytometry detections and related systems and/or kits. Certain methods are directed to a method for detecting one or more biological targets of a sample in a detection assay, comprising: providing a molecular probe, comprising a binding moiety and an oligonucleotide sequence, to a sample comprising one or more biological targets; binding the one or more biological targets with the binding moiety; providing a detectable component to the sample, wherein the detectable component comprises a signal generating moiety conjugated to an oligonucleotide sequence complementary to the oligonucleotide sequence of the molecular probe; hydridizing the oligonucleotide sequence of the target-bound molecular probe to the detectable component; and detecting a signal generated from the hydridized detectable component. Various other embodiments, applications etc. are disclosed herein.

Abstract: Systems, methods, and devices are provided that allow for high-availability, redundant, cryptographically secure storage of secret data and other data on a blockchain. In an embodiment, a plurality of shards of secret data are received from a user and encrypted with shard manager public keys. The encrypted shards are stored on an authoritative blockchain, allowing for secure storage and use of the secret data by the owner and/or the blockchain.

Abstract: An incorrect transmission, of a record of data to a distributed ledger system, can be prevented. A first signal can be received. The first signal can include a first instruction to cause the record to be transmitted to the system. One or more items of information in the record can be determined. A delay of time to be elapsed, before a transmission of the record to the system, can be set in response to a receipt of the first signal and a determination of the one or more items. The transmission of the record to the system can be caused to occur after the delay has elapsed. The transmission of the record to the system can be prevented in response to a receipt of a second signal before the delay has elapsed. The second signal can include a second instruction that supersedes the first instruction.

Abstract: Punch assembly that enable selective securement and release of punch tips to a punch body (or holder) of the assemblies, wherein various retain/release systems can be used with the punch body, specifically relative to triggering mechanisms of such systems and their functioning and use with ancillary components relative to securing and releasing the punch tip, without adversely affecting long-term efficiency and effectiveness of the assemblies.