Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of liver X receptors (LXRs).

Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of liver X receptors (LXRs).

Abstract: The invention provides compounds having Formula Ia, or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4 and Y are as defined in the specification; as well as pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).

Abstract: Individualized, adaptable media presentations and a method for creating them are disclosed. In particular, each media presentation is generated according to user input and predetermined templates, overlaid with at least an instruction and an accompaniment layers generated from media clips (audio, video, audio/video) selected based on provided user data. The instruction and accompaniment layers are variable by the user and may then be overridden by the removal and replacement of individual media clips within the layer. The method and resultant media presentations as seen as ideal for exercise and physical training regimens, though may be utilized in any situation where recreation and instruction media presentation are used.

Abstract: The present invention relates to silicon-containing glass powder particles suitable for use in providing plant available silicon to a plant growth medium or a plant, a method for producing these particles and a method of providing plant available silicon to a plant growth medium or a plant using the particles. The present invention also relates to a method of improving plant growth and a method of improving plant yield which include applying the particles of the invention to the plant or plant growth medium.

Abstract: A mudflap assembly comprising a bracket for connection to a vehicle and a hanger extended therefrom. A mudflap is connected to one end of the hanger, while the bracket rotatable receives the other end and maintains the hanger in an initial resting position until the hanger is acted upon by a sufficient horizontal force. A bulge or detent on the bracket resists horizontal movement of the hanger.

Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of liver X receptors (LXRs).

Abstract: The present invention relates to inhibition of viruses, e.g., HIV using pyrrolidones and compounds related to pyrrolidones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.

Abstract: The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).

Abstract: The invention provides compounds of formula (Ia), (Ic), (Ig) and (Ik), pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).

Abstract: The present invention relates to inhibition of viruses, e.g., HIV using pyrrolidones and compounds related to pyrrolidones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.

Abstract: The present invention relates to phenyl-substituted pyrrolidones and compounds related to phenyl-substituted pyrrolidones. One use of these compounds is for the inhibition of viruses, e.g., HIV. The invention further relates to methods of malting these compounds, methods of identifying the efficacy of these compounds, and methods of using these compounds to inhibit or prevent HIV infection and related disease states such as AIDS.

Abstract: The present invention relates to inhibition of viruses, e.g., HIV using pyrrolidones and compounds related to pyrrolidones. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.

Abstract: A mudflap assembly comprising a bracket for connection to a vehicle and a swiveling support is claimed. A mudflap hanger arm rotatably couples with the bracket via a hinged pin joint. A ramping sleeve is coupled to the pin between the hanger arm and bracket on one end, and a spring installed on the other end provides compressive force against the hanger arm when it travels up the ramping sleeve in response to a horizontal force.

Abstract: A mudflap retainer comprising two halves wherein each half has protrusions to extend through the standard hole placements of the mudflap. The halves are mated together through the mudflap creating a wedge at the top of the mudflap. The mudflap can then be inserted through a slot in a mudflap hanger assembly wherein the wedge created by the retainer couples with the mudflap hanger assembly.

Abstract: A mudflap assembly comprising a bracket for connection to a vehicle and a hanger extended therefrom. A mudflap is connected to one end of the hanger, while the bracket rotatable receives the other end and maintains the hanger in an initial resting position until the hanger is acted upon by a sufficient horizontal force. A bulge or detent on the bracket resists horizontal movement of the hanger.

Abstract: A mudflap assembly comprising a bracket for connection to a vehicle and a swiveling support is claimed. A mudflap support bar is connected to an upper end of the swiveling support for supporting a mudflap. The bracket rotatably receives the free lower end of the swiveling support hanger and maintains the mudflap support bar in an initial resting position until the support bar is acted upon by a horizontal force. A spring installed on the free lower end of the swiveling support hanger provides compressive force against the bracket.

Abstract: A method and circuitry for pre-conditioning an electrical signal. The method comprises limiting the strength of the signal to not exceed a limit signal strength corresponding to the onset of substantial non-linear response of an amplifier to which the limited signal is to be supplied for amplification.

Abstract: The present invention relates to inhibition of viruses, e.g., HIV using oxindoles and compounds related to oxindoles. The invention further relates to methods for identifying and using agents, including small molecule chemical compositions that inhibit HIV in a cell; as well as to methods of prophylaxis, and therapy related to HIV infection and related disease states such as AIDS.

Abstract: A system is provided for permitting movement of a vehicle having brakes while an auxiliary component of the vehicle is operated by the vehicle. The system includes a pressurized fluid source. A control device is coupled to the pressurized fluid source and the brakes of the vehicle to release the brakes in response to a first signal and to at least partially apply the brakes in response to a second signal. A controller applies the first signal to the control device when at least one of a first set of conditions exist and applies the second signal to the control device when a second set of conditions exist.