Patents by Inventor David Dixon

David Dixon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190101594
    Abstract: A control system for an electric motor comprises a current controller which produces a set of voltage demands for the motor, a current sensing means arranged to produce a current sensing output indicative of electric current in the motor, and a current signal processing means arranged to process the current sensing output signal to produce a modified current signal in which at least one harmonic component present in the current sensing output signal due to inaccuracies in the current measurement is removed or substantially reduced. The modified current signal is combined with a demanded motor current to provide the input to the current controller.
    Type: Application
    Filed: March 17, 2017
    Publication date: April 4, 2019
    Applicant: TRW Limited
    Inventors: Christopher David Dixon, Peter Geoffrey Scotson
  • Publication number: 20190015377
    Abstract: The present disclosure provides methods of treating pulmonary arterial hypertension (PAH) in a subject in need thereof. Compositions for use in these methods are also provided.
    Type: Application
    Filed: July 16, 2018
    Publication date: January 17, 2019
    Applicant: Peloton Therapeutics, Inc.
    Inventors: Darryl David Dixon, Jonas Grina, John A. Josey, James P. Rizzi, Stephen T. Schlachter, Eli M. Wallace, Bin Wang, Paul Wehn, Rui Xu, Hanbiao Yang
  • Patent number: 10173186
    Abstract: A pulsed gas mixing apparatus is provided. The pulsed gas mixing apparatus may include a mixing plate having a top side that is substantially smooth, and a bottom side that includes a plurality of ribs. The pulsed gas mixing apparatus may also include a supply tube configured to be coupled to the mixing plate and supply a mixing gas that is used to mix the contents a container in which the pulsed gas mixing apparatus is installed.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: January 8, 2019
    Assignee: Micro Matic USA, LLC
    Inventors: Michael A. Tomlinson, David Dixon
  • Patent number: 10144711
    Abstract: The present disclosure relates to HIF-2? inhibitors and methods of making and using them for treating cancer. Certain compounds were potent in HIF-2? scintillation proximity assay, luciferase assay, and VEGF ELISA assay, and led to tumor size reduction and regression in 786-O xenograft bearing mice in vivo.
    Type: Grant
    Filed: November 7, 2017
    Date of Patent: December 4, 2018
    Assignee: PELOTON THERAPEUTICS, INC.
    Inventors: Darryl David Dixon, Jonas Grina, John A. Josey, James P. Rizzi, Stephen T. Schlachter, Eli M. Wallace, Bin Wang, Paul Wehn, Rui Xu, Hanbiao Yang
  • Publication number: 20180265834
    Abstract: A cassette comprising: a first reservoir arranged to couple to a first actuator for imparting flow to a cell-containing solution in a first direction through a filter; a second reservoir arranged to couple to a second actuator for imparting flow to a cell-containing solution in a second direction through the filter; the filter being in fluid communication with the first and second reservoirs, and when connected to a filtration unit is in further fluid communication to a sample inlet, and a sample outlet; wherein, the cassette is disposable and housed by a connector being removeably adjoinable to the filtration unit, the filtration unit comprising the first and second actuators and one or more valves.
    Type: Application
    Filed: November 17, 2015
    Publication date: September 20, 2018
    Applicant: Bend Research Inc.
    Inventors: David Dixon Newbold, Clinton Boyd Pepper, David Andrew Hansen
  • Publication number: 20180229467
    Abstract: A tool can include a substrate with a support surface and at least one mechanical registration feature. The tool can also include a removable wear material including a matrix material. The removable wear material can include a matrix material shaped to be received by the at least one mechanical registration feature of the substrate. The removable wear material can be attached to the substrate so that the at least one mechanical registration feature registers the removable wear material.
    Type: Application
    Filed: June 7, 2016
    Publication date: August 16, 2018
    Applicant: Schlumberger Technology Corporation
    Inventors: Stuart David Dixon Walker, Fabio Cappi, Are Funderud
  • Patent number: 10040767
    Abstract: Benzimidazole derivatives of Formula I, that modulate the activity of ACSS2 are disclosed for therapeutic use. The fused imidazole ring of the compounds disclosed has a diarylmethyl or diarylmethanol moiety attached at the 2-position and the as compounds have at least one other substituent at the 5 or 6 position of the benzimidazole. Also disclosed are methods of using the benzimidazole compounds for the treatment of diseases or disorders, such as cancer.
    Type: Grant
    Filed: May 14, 2015
    Date of Patent: August 7, 2018
    Assignee: Peloton Therapeutics, Inc.
    Inventors: Darryl David Dixon, Jonas Grina, John A. Josey, James P. Rizzi, Stephen T. Schlachter, Eli M. Wallace, Bin Wang, Paul Wehn, Hanbiao Yang
  • Publication number: 20180162807
    Abstract: Aromatic entities that modulate HIF-2? activity, pharmaceutical compositions containing the aromatic entities, and methods of using these chemical entities for treating proliferative diseases and conditions associated with HIF-2? activity are described herein.
    Type: Application
    Filed: March 4, 2016
    Publication date: June 14, 2018
    Inventors: Darryl David DIXON, Jonas GRINA, John A. JOSEY, James P. RIZZI, Stephen T. SCHLACHTER, Eli M. WALLACE, Bin WANG, Paul WEHN, Rui Xu, Hanbiao YANG
  • Publication number: 20180155279
    Abstract: The present disclosure relates to HIF-2? inhibitors and methods of making and using them for treating cancer. Certain compounds were potent in HIF-2? scintillation proximity assay, luciferase assay, and VEGF ELISA assay, and led to tumor size reduction and regression in 786-O xenograft bearing mice in vivo.
    Type: Application
    Filed: November 7, 2017
    Publication date: June 7, 2018
    Inventors: Darryl David Dixon, Jonas Grina, John A. Josey, James P. Rizzi, Stephen T. Schlachter, Eli M. Wallace, Bin Wang, Paul Wehn, Rui Xu, Hanbiao Yang
  • Publication number: 20180135148
    Abstract: This application pertains to methods of recovering metals from metal sulfides that involve contacting the metal sulfide with an acidic sulfate solution containing ferric sulfate and a reagent that has a thiocarbonyl functional group, wherein the concentration of reagent in the acidic sulfate solution is sufficient to increase the rate of metal ion extraction relative to an acidic sulfate solution that does not contain the reagent, to produce a pregnant solution containing the metal ions.
    Type: Application
    Filed: April 15, 2016
    Publication date: May 17, 2018
    Inventors: David DIXON, Oscar OLVERA OLMEDO, Edward ASSELIN, Ahmad GHAHREMANINEZHAD, Zihe REN
  • Patent number: 9969689
    Abstract: The present disclosure relates to HIF-2? inhibitors and methods of making and using them for treating cancer. Certain compounds were potent in HIF-2? scintillation proximity assay, luciferase assay, and VEGF ELISA assay, and led to tumor size reduction and regression in 786-O xenograft bearing mice in vivo.
    Type: Grant
    Filed: February 22, 2017
    Date of Patent: May 15, 2018
    Assignee: PELOTON THERAPEUTICS, INC.
    Inventors: Darryl David Dixon, Jonas Grina, John A. Josey, James P. Rizzi, Stephen T. Schlachter, Eli M. Wallace, Bin Wang, Paul Wehn, Rui Xu, Hanbiao Yang
  • Patent number: 9966882
    Abstract: A control system for an electric motor comprises a current sensing means arranged to produce a current sensing output indicative of electric current in the motor, current control means arranged to receive the current sensing output and to output a voltage demand indicative of voltages to be applied to the motor, and current sensing correction means arranged to monitor the voltage demand to measure distortion in the current sensing output and to generate a correction signal which is arranged to correct the distortion.
    Type: Grant
    Filed: February 16, 2011
    Date of Patent: May 8, 2018
    Assignee: TRW LIMITED
    Inventors: Connel Brett Williams, Christopher David Dixon, Robert James Huxford
  • Patent number: 9908845
    Abstract: The present disclosure relates to HIF-2? inhibitors and methods of making and using them for treating cancer. Certain compounds were potent in HIF-2? scintillation proximity assay, luciferase assay, and VEGF ELISA assay, and led to tumor size reduction and regression in 786-O xenograft bearing mice in vivo.
    Type: Grant
    Filed: September 5, 2014
    Date of Patent: March 6, 2018
    Assignee: PELOTON THERAPEUTICS, INC.
    Inventors: Darryl David Dixon, Jonas Grina, John A. Josey, James P. Rizzi, Stephen T. Schlachter, Eli M. Wallace, Bin Wang, Paul Wehn, Rui Xu, Hanbiao Yang
  • Publication number: 20180049995
    Abstract: Chemical compounds that modulate HIF-2? activity, their polymorphs, pharmaceutical compositions, and methods of treatment of diseases and conditions associated with HIF-2?, are described herein.
    Type: Application
    Filed: March 10, 2016
    Publication date: February 22, 2018
    Inventors: Darryl David DIXON, Peter J. STENGEL, Bin WANG
  • Patent number: 9896418
    Abstract: The present disclosure relates to HIF-2? inhibitors and methods of making and using them for treating cancer. Certain compounds were potent in HIF-2? scintillation proximity assay, luciferase assay, and VEGF ELISA assay, and led to tumor size reduction and regression in 786-O xenograft bearing mice in vivo.
    Type: Grant
    Filed: February 22, 2017
    Date of Patent: February 20, 2018
    Assignee: PELOTON THERAPEUTICS, INC.
    Inventors: Darryl David Dixon, Jonas Grina, John A. Josey, James P. Rizzi, Stephen T. Schlachter, Eli M. Wallace, Bin Wang, Paul Wehn, Rui Xu, Hanbiao Yang
  • Patent number: 9884843
    Abstract: The present disclosure relates to cyclic sulfones and sulfoximines that are HIF-2a inhibitors and methods of making and using them for treating cancers. In another aspect, the present disclosure provides a pharmaceutical composition comprising a compound described herein and a pharmaceutically acceptable carrier or excipient. The compound may exist in an amorphous form, a crystalline form, or as a salt, solvate, or hydrate. In another aspect, the present disclosure provides a method of treating renal cell carcinoma by administrating a therapeutically effective amount of a compound described herein or a pharmaceutical composition thereof to a subject in need of such treatment.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: February 6, 2018
    Assignee: PELOTON THERAPEUTICS, INC.
    Inventors: Darryl David Dixon, Jonas Grina, John A. Josey, James P. Rizzi, Stephen T. Schlachter, Eli M. Wallace, Bin Wang, Paul Wehn, Rui Xu, Hanbiao Yang
  • Publication number: 20180028527
    Abstract: This invention relates a therapeutic pharmaceutical composition comprising: a mixture including an opioid; polyethylene oxide in an amount of about 3 to about 40 wt % of the composition; a disintegrant; and a surfactant; wherein the disintegrant is present in an amount sufficient to cause the pharmaceutical composition to exhibit an immediate release profile.
    Type: Application
    Filed: October 5, 2017
    Publication date: February 1, 2018
    Applicant: Acura Pharmaceuticals, Inc.
    Inventors: Vijai KUMAR, David DIXON, Divya TEWARI, Dilip B. WADGAONKAR
  • Publication number: 20170217891
    Abstract: The present disclosure relates to HIF-2? inhibitors and methods of making and using them for treating cancer. Certain compounds were potent in HIF-2? scintillation proximity assay, luciferase assay, and VEGF ELISA assay, and led to tumor size reduction and regression in 786-O xenograft bearing mice in vivo.
    Type: Application
    Filed: February 22, 2017
    Publication date: August 3, 2017
    Inventors: Darryl David Dixon, Jonas Grina, John A. Josey, James P. Rizzi, Stephen T. Schlachter, Eli M. Wallace, Bin Wang, Paul Wehn, Rui Xu, Hanbiao Yang
  • Publication number: 20170217892
    Abstract: The present disclosure relates to HIF-2? inhibitors and methods of making and using them for treating cancer. Certain compounds were potent in HIF-2? scintillation proximity assay, luciferase assay, and VEGF ELISA assay, and led to tumor size reduction and regression in 786-O xenograft bearing mice in vivo.
    Type: Application
    Filed: February 22, 2017
    Publication date: August 3, 2017
    Inventors: Darryl David Dixon, Jonas Grina, John A. Josey, James P. Rizzi, Stephen T. Schlachter, Eli M. Wallace, Bin Wang, Paul Wehn, Rui Xu, Hanbiao Yang
  • Publication number: 20170200201
    Abstract: A computer-implemented method may provide a dashboard configured to monitor postings from users and process user postings placed on the dashboard for earned content. The method may then select earned content from the dashboard and generate an advertising unit comprising the selected earned content. The generated advertising unit may then be distributed in a targeted fashion to at least one user.
    Type: Application
    Filed: January 13, 2017
    Publication date: July 13, 2017
    Inventors: Erin Lanuti, Benoit Bignon, Will Parker, Sebastian Shapiro, Monty Kiernan, David Dixon, Julia Soukhareva, Guillaume Guay