Patents by Inventor David Ho

David Ho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180163221
    Abstract: The present disclosure relates to transgenic plants that over-express PP2CABA and methods of using such for enhancing osmotic stress tolerance.
    Type: Application
    Filed: December 12, 2017
    Publication date: June 14, 2018
    Applicant: Academia Sinica
    Inventors: Su-May Yu, Chun-Hsien Lu, Tuan-Hua David Ho, Shuen-Fang Lo
  • Publication number: 20180155327
    Abstract: The present invention provides antitumor agents comprising substituted pyrimidine derivatives and pharmaceutically-acceptable formulations thereof, methods for making novel compounds and methods for using the compounds. The compounds and compositions in accordance with the invention have utility in treatment of a variety of diseases and have kinase inhibitory activities.
    Type: Application
    Filed: February 27, 2015
    Publication date: June 7, 2018
    Inventors: Chunlin Tao, Qinwei Wang, Laxman Nallan, David Ho, Tulay Polat, Forrest Arp, Paul Weingarten
  • Patent number: 9943075
    Abstract: The present invention provides compositions (i.e., preservation solutions) for preserving biologies comprising at least one membrane penetrable sugar, at least one membrane impenetrable sugar, at least one anti-microbial agent, at least one anti-oxidant, adenosine, albumin, a salt, a buffer, and a chelating agent, and to methods of using such preservation solutions to preserve biologies.
    Type: Grant
    Filed: February 16, 2011
    Date of Patent: April 17, 2018
    Assignee: HEMEMICS BIOTECHNOLOGIES, INC.
    Inventors: David Ho, Stephen P. Bruttig
  • Publication number: 20180086752
    Abstract: Compounds and compositions are presented that inhibit K-ras, and especially mutant K-ras. Certain compounds preferentially or even selectively inhibit specific forms of mutant K-Ras, and particularly the G12D mutant form.
    Type: Application
    Filed: April 1, 2016
    Publication date: March 29, 2018
    Inventors: Shahrooz Rabizadeh, Kayvan Niazi, Sasha Buzko, Paul Weingarten, Heather McFarlane, Anna Juncker-Jensen, Justin Golovato, Patrick Soon-Shiong, Chunlin Tao, David Ho
  • Patent number: 9725736
    Abstract: The present invention relates to mutant gibberellin 2-oxidase (GA2ox) genes and uses thereof. In particular, the effective mutations disclosed herein can reduce GA2ox enzymatic activity to different extents, leading to various degrees of GA deficient yet beneficial agronomic traits in transgenic plants.
    Type: Grant
    Filed: November 29, 2013
    Date of Patent: August 8, 2017
    Assignee: Academia Sinica
    Inventors: Su-May Yu, Shuen-Fang Lo, Liang-Jwu Chen, Tuan-Hua David Ho
  • Publication number: 20170088544
    Abstract: The present invention relates generally to the use of compounds to treat a variety of disorders, diseases and pathologic conditions and more specifically to the use of substituted indol-5-ol derivatives to modulate protein kinases and for treating protein kinase-mediated diseases.
    Type: Application
    Filed: October 4, 2016
    Publication date: March 30, 2017
    Inventors: Chunlin Tao, Qinwei Wang, David Ho, Tulay Polat, Laxman Nallan, Patrick Soon-Shiong
  • Publication number: 20160379339
    Abstract: Customizing virtual assets is disclosed, including: transforming each of a plurality of initially identical copies of a virtual asset or a portion thereof to isolate a feature of the virtual asset or portion thereof; and enabling the isolated feature to be changed by a user in at least one of the transformed copies. In some embodiments, customizing virtual assets includes: receiving a three-dimensional model associated with the virtual asset; receiving an indication to save a two-dimensional virtual asset based on the 3D model with a 2D image wrapped on it; and using the 3D model with the 2D image wrapped on it to generate the 2D virtual asset.
    Type: Application
    Filed: September 9, 2016
    Publication date: December 29, 2016
    Inventors: David Ho, Dennis Suggs
  • Patent number: 9490934
    Abstract: Methods, systems, and apparatus for crosstalk avoidance in a telecommunications network are disclosed. In one aspect a method includes determining, by a network element and for each vectoring group from multiple vectoring groups, a transmission load of the vectoring group based on transmission loads of links within the vectoring group; identifying, by the network element, a resource allocation interval (RAI) that is shared by the multiple vectoring groups; determining, based on the transmission load of each vectoring group and by the network element, a first portion of the RAI that will be a normal operation interval (NOI) and a second portion of the RAI that will be a discontinuous operation interval (DOI); transmitting, by the network element, data over all of the multiple vectoring groups during at least a portion of the NOI; and transmitting, by the network element, data over fewer than all of the vectoring groups during the entire DOI.
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: November 8, 2016
    Assignee: Adtran, Inc.
    Inventors: Richard Lee Goodson, Kenneth David Ho
  • Patent number: 9472161
    Abstract: Customizing virtual assets is disclosed, including: transforming each of a plurality of initially identical copies of a virtual asset or a portion thereof to isolate a feature of the virtual asset or portion thereof; and enabling the isolated feature to be changed by a user in at least one of the transformed copies. In some embodiments, customizing virtual assets includes: receiving a three-dimensional model associated with the virtual asset; receiving an indication to save a two-dimensional virtual asset based on the 3D model with a 2D image wrapped on it; and using the 3D model with the 2D image wrapped on it to generate the 2D virtual asset.
    Type: Grant
    Filed: November 30, 2011
    Date of Patent: October 18, 2016
    Assignee: CIE Games LLC
    Inventors: David Ho, Dennis Suggs
  • Patent number: 9458137
    Abstract: The present invention relates generally to the use of compounds to treat a variety of disorders, diseases and pathologic conditions and more specifically to the use of substituted indol-5-ol derivatives to modulate protein kinases and for treating protein kinase-mediated diseases.
    Type: Grant
    Filed: November 5, 2013
    Date of Patent: October 4, 2016
    Assignee: NantBioScience, Inc.
    Inventors: Chunlin Tao, Qinwei Wang, David Ho, Tulay Polat, Laxman Nallan, Patrick Soon-Shiong
  • Publication number: 20160242997
    Abstract: An acupressure device applies pressure to the pericardium acupressure point on a wrist of a user for the relief of nausea. The device has a frame element including two opposing end portions with adhesive thereon for adhering to skin of the user. A protruding element is supported on the frame element to protrude from an inner surface of the frame element at a location which is between the two end portions of the frame element in a lateral direction of the frame element. The frame element is formed of a resilient material which is arranged to undergo bending stresses when flexed about a bending axis oriented transversely to the lateral direction whereby the protruding element is arranged to apply pressure to the pericardium acupressure point when the adhesive material at the two end portions is adhered to skin of the user at laterally opposing sides of the pericardium acupressure point.
    Type: Application
    Filed: May 5, 2016
    Publication date: August 25, 2016
    Inventor: Barry Michael David Ho
  • Patent number: 9409903
    Abstract: The invention provides triazine compounds and methods of their use to modulate protein kinases and to treat diseases mediated by said protein kinases.
    Type: Grant
    Filed: November 3, 2014
    Date of Patent: August 9, 2016
    Assignee: NantBioScience, Inc.
    Inventors: Chunlin Tao, Qinwei Wang, David Ho, Laxman Nallan, Tulay Polat, Xiaowen Sun, Neil Desai
  • Publication number: 20160177329
    Abstract: The present invention relates to a method for inhibiting sprouting, particularly pre-harvest sprouting, in plant seeds, by introducing a polynucleotide encoding a FCA protein into the plant.
    Type: Application
    Filed: August 18, 2015
    Publication date: June 23, 2016
    Applicant: Academia Sinica
    Inventors: Tuan-hua David Ho, Wan-chi Lin, Kuan-Ying Huang
  • Publication number: 20160160231
    Abstract: Transgenic plants that over-express a Big Grain 2 (BG2) gene and methods of using such for improving the growth, productivity, or stress tolerance of a plant.
    Type: Application
    Filed: December 7, 2015
    Publication date: June 9, 2016
    Applicant: Academia Sinica
    Inventors: SU-MAY YU, Tuan-Hua David Ho, Shuen-Fang Lo, Ching-Yi Liao
  • Publication number: 20160138037
    Abstract: A method for enhancing one or more yield-related traits in plants relative to control plants comprises modulating expression in a plant of a nucleic acid encoding a PAE1 (pectin acetylesterase) polypeptide. PAE1-encoding nucleic acids, and constructs comprising the same, are used in performing the method, and plants having one or more enhanced yield-related traits are obtained.
    Type: Application
    Filed: June 6, 2014
    Publication date: May 19, 2016
    Applicant: BASF Plant Science Compnay GmbH
    Inventors: Christophe REUZEAU, Su-May YU, Yue-Le HSING, Tuan-Hua David HO, Shuen-Fang LO
  • Publication number: 20160046956
    Abstract: The present invention relates to mutant gibberellin 2-oxidase (GA2ox) genes and uses thereof. In particular, the effective mutations disclosed herein can reduce GA2ox enzymatic activity to different extents, leading to various degrees of GA deficient yet beneficial agronomic traits in transgenic plants.
    Type: Application
    Filed: November 29, 2013
    Publication date: February 18, 2016
    Applicant: Academia Sinica
    Inventors: Su-May Yu, Shuen-Fang Lo, Liang-Jwu Chen, Tuan-Hua David Ho
  • Publication number: 20150381309
    Abstract: Methods, systems, and apparatus for crosstalk avoidance in a telecommunications network are disclosed. In one aspect a method includes determining, by a network element and for each vectoring group from multiple vectoring groups, a transmission load of the vectoring group based on transmission loads of links within the vectoring group; identifying, by the network element, a resource allocation interval (RAI) that is shared by the multiple vectoring groups; determining, based on the transmission load of each vectoring group and by the network element, a first portion of the RAI that will be a normal operation interval (NOI) and a second portion of the RAI that will be a discontinuous operation interval (DOI); transmitting, by the network element, data over all of the multiple vectoring groups during at least a portion of the NOI; and transmitting, by the network element, data over fewer than all of the vectoring groups during the entire DOI.
    Type: Application
    Filed: September 30, 2014
    Publication date: December 31, 2015
    Inventors: Richard Lee Goodson, Kenneth David Ho
  • Publication number: 20150381233
    Abstract: Methods, systems, and apparatus for crosstalk avoidance in a telecommunications network are disclosed. In one aspect a method includes determining, by a network element and for each vectoring group from multiple vectoring groups, a transmission load of the vectoring group based on transmission loads of links within the vectoring group; allocating, by the network element, a different transmission interval to each vectoring group from the multiple vectoring groups based on the transmission load of the vectoring group and transmission loads of other vectoring groups in the multiple vectoring groups; and transmitting, during each different transmission interval, at least a portion of the transmission load of the vectoring group that was allocated the different transmission interval.
    Type: Application
    Filed: September 30, 2014
    Publication date: December 31, 2015
    Inventors: Richard Lee Goodson, Kenneth David Ho, Marin Kuipers
  • Publication number: 20150344900
    Abstract: The present invention relates to a method for enhancing root growth of a plant by introducing a polynucleotide encoding late embryogenesis abundant protein, group 3 (LEA3) into the plant. Plant root architecture is essential for its functions in water and nutrient uptake, anchorage and interactions with microbes in the soil.
    Type: Application
    Filed: November 21, 2013
    Publication date: December 3, 2015
    Applicant: Academia Sinica
    Inventors: Su-May Yu, Yi-Shih Chen, Shuen-Fang Lo, Tuan-Hua David Ho
  • Patent number: 9165394
    Abstract: The present invention sets forth a method for supporting enhanced audio on a graphics processing unit (GPU) in a computing device having a graphics subsystem. In one embodiment, the method includes the steps of determining whether an option of a GPU audio output is enabled and the graphics subsystem and a first external output device is connected, and routing a first audio stream to the GPU of the graphics subsystem for processing when the option of the GPU audio output is enabled and the graphics subsystem and the first external output device is in connection and causing the processed first audio stream to be transferred along a first transmission path to the first external output device, or otherwise causing a second audio stream to be transferred along a second transmission path to a second external output device.
    Type: Grant
    Filed: October 13, 2009
    Date of Patent: October 20, 2015
    Assignee: NVIDIA Corporation
    Inventors: Shany-I Chan, Ching-Yee Feng, Shih-Da Wu, Tseng-Ying Lee, Li-Kai Cheng, Li-Ling Chou, Yu-Kuo Chiang, Yu-Li (David) Ho