Patents by Inventor David Ho

David Ho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9078902
    Abstract: The invention provides Triazine derivatives and further provides methods of using these compounds to modulate protein kinases and for treating diseases and conditions mediated by protein kinases.
    Type: Grant
    Filed: June 9, 2010
    Date of Patent: July 14, 2015
    Assignee: NantBioScience, Inc.
    Inventors: Chunlin Tao, Qinwei Wang, Laxman Nallan, Tulay Polat, David Ho, Neil Desai
  • Publication number: 20150157009
    Abstract: The present invention provides compositions (i.e., preservation solutions) for preserving biologics comprising at least one membrane penetrable sugar, at least one membrane impenetrable sugar, at least one anti-microbial agent, at least one anti-oxidant, adenosine albutinum, a salt, a buffer, and a chelating agent, and to methods of using such preservation solutions to preserve biologies.
    Type: Application
    Filed: February 13, 2015
    Publication date: June 11, 2015
    Inventors: David Ho, Stephen Bruttig
  • Patent number: 9006535
    Abstract: In a transgenic plant, a stress-responsive promoter containing CE3 and ABRE2 from HVA1 ABRC3 and CE1 from HVA22 ABRC1, directs low background expression of a gene under normal growth conditions, but is highly inducible by an abiotic stress, such as abscisic acid, dehydration, salt or cold. Compared with the wild type plant, the transgenic plant that expresses a stress-resistant gene under the control of the stress-responsive promoter is more resistant and/or tolerant to abiotic stresses and exhibits similar or higher growth rate and strength under regular or normal environmental conditions.
    Type: Grant
    Filed: November 19, 2007
    Date of Patent: April 14, 2015
    Assignee: Academia Sinica
    Inventors: Su-May Yu, Tuan-Hua David Ho
  • Publication number: 20150057285
    Abstract: The invention provides triazine compounds and methods of their use to modulate protein kinases and to treat diseases mediated by said protein kinases.
    Type: Application
    Filed: November 3, 2014
    Publication date: February 26, 2015
    Inventors: Chunlin Tao, Qinwei Wang, David Ho, Laxman Nallan, Tulay Polat, Xiaowen Sun, Neil Desai
  • Publication number: 20150007367
    Abstract: The present invention relates generally to the field of molecular biology and concerns a method for enhancing various economically important yield-related traits in plants. More specifically, the present invention concerns a method for enhancing yield-related traits in plants by modulating expression in a plant of a nucleic acid encoding an FBO13 (F-box and other domain containing protein) polypeptide. The present invention also concerns plants having modulated expression of a nucleic acid encoding an FBO13 polypeptide, which plants have enhanced yield-related traits relative to control plants. The invention also provides hitherto unknown FBO13-encoding nucleic acids, and constructs comprising the same, useful in performing the methods of the invention.
    Type: Application
    Filed: November 22, 2012
    Publication date: January 1, 2015
    Applicant: BASF Plant Science Company GmbH
    Inventors: Christophe Reuzeau, Su-May Yu, Swee-Suak Ko, Yue-le Hsing, Tuan-Hua David Ho, Shuen-Fang Lo
  • Patent number: 8877924
    Abstract: The invention provides triazine compounds and methods of their use to modulate protein kinases and to treat diseases mediated by said protein kinases.
    Type: Grant
    Filed: June 8, 2010
    Date of Patent: November 4, 2014
    Assignee: NantBio Inc.
    Inventors: Chunlin Tao, Qinwei Wang, David Ho, Laxman Nallan, Tulay Polat, Xiaowen Sun, Neil Desai
  • Patent number: 8772459
    Abstract: In one embodiment, a minibody monomer that binds PSMA is provided. The minibody monomer is encoded by a nucleotide sequence comprising, from N-terminus to C-terminus, an scFv sequence that can bind PSMA, an artificial hinge sequence, and a human IgG CH3 sequence. In another embodiment, a CysDB monomer that binds PSMA is provided. The CysDB monomer may be encoded by a nucleotide sequence comprising, from N-terminus to C-terminus, an scFv sequence that can bind PSMA and a cysteine tail. In other embodiments, methods for diagnosing or treating a cancer associated with PSMA expression in a subject are provided.
    Type: Grant
    Filed: December 2, 2010
    Date of Patent: July 8, 2014
    Assignee: ImaginAb, Inc.
    Inventors: David Ho, Tove Olafsen, Arye Lipman
  • Patent number: 8759614
    Abstract: A method of making a transgenic plant by transforming into a host plant a recombinant DNA construct that expresses in the transgenic plant a rice polypeptide and the transgenic plant thus produced.
    Type: Grant
    Filed: May 1, 2009
    Date of Patent: June 24, 2014
    Assignee: Academia Sinica
    Inventors: Su-May Yu, Swee-Suak Ko, Yue-Ie C. Hsing, Tuan-Hua David Ho, Shuen-Fang Lo
  • Publication number: 20140165229
    Abstract: The present invention provides a method for enhancing yield-related traits in plants by modulating expression in a plant of a nucleic acid encoding an ELNINI (comprising an ELNINI signature sequence) polypeptide. The present invention also provides plants having modulated expression of a nucleic acid encoding an ELNINI polypeptide, which plants have enhanced yield-related traits relative to control plants. The present invention also provides constructs comprising ELNINI-encoding nucleic acids, useful in performing the methods of the present invention.
    Type: Application
    Filed: June 19, 2012
    Publication date: June 12, 2014
    Applicant: BASF Plant Science Company GmbH
    Inventors: Christophe Reuzeau, Su-May Yu, Swee-Suak Ko, Yue-Le Hsing, Tuan-Hua David Ho, Shuen-Fang Lo
  • Publication number: 20140136211
    Abstract: A method for controlling a mobile information device based on verbal input from a user is presented. The method comprises waiting for a predetermined verbal input from a user. The method further comprises controlling a functional module of the mobile information device to determine a value within a predetermined range for a functional parameter in response to a first portion of the verbal input. Finally, the method comprises executing a functional operation by the functional module based on a determined value, in response to a second portion of the verbal input, wherein the second portion follows the first portion.
    Type: Application
    Filed: March 20, 2013
    Publication date: May 15, 2014
    Applicant: NVIDIA Corporation
    Inventors: Li-Ling CHOU, David HO
  • Publication number: 20140129957
    Abstract: A method for creating a personalized user interface on a mobile information device is provided. The method includes the steps of: filtering out from a plurality of applications APPs installed on the mobile information device one or more said applications according to a personalization filtering criterion, such as a given number of most frequently used APPs; displaying the one or more filtered APPs on a visualized menu; and executing a selected one of the one or more filtered APPs on the visualized menu in response to a selection entered by a user.
    Type: Application
    Filed: December 28, 2012
    Publication date: May 8, 2014
    Applicant: NVIDIA CORPORATION
    Inventors: Li-Ling Chou, Yu-Li David Ho
  • Patent number: 8643655
    Abstract: The present invention sets forth a method and system for communicating with an external device through a processing unit in a graphics system of a computing device. In one embodiment, the method comprises allocating a first set of memory buffers having a first memory buffer and a second memory buffer in the graphics system based on an identification information of the external device, and invoking a first thread processor of the processing unit of the graphics system to perform services associated with a physical layer according to the identification information of the external device by storing a first data stream received from the external device through an I/O interface of the processing unit of the graphics system in the first memory buffer and retrieving a second data stream from the second memory buffer for transmission to the external device through the I/O interface.
    Type: Grant
    Filed: November 12, 2009
    Date of Patent: February 4, 2014
    Assignee: Nvidia Corporation
    Inventors: Shany-I Chan, Ching-Yee Feng, Shih-Da Wu, Li-Kai Cheng, Li-Ling Chou, Yu-Kuo Chiang, Yu-Li (David) Ho
  • Patent number: 8637024
    Abstract: Disclosed herein are fusion antibodies created to provide both an antigen-binding site that targets the CD4 receptor and an antigen-binding site that targets the HIV envelope. The fusion antibodies disclosed herein provide improved potency and breadth against HIV as compared to monospecific antibodies, and additionally provide high barrier against viral resistance. Also disclosed are pharmaceutical formulations and therapeutic methods utilizing such fusion proteins.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: January 28, 2014
    Assignee: The Rockefeller University
    Inventors: David Ho, Yaoxing Huang, Craig Pace, Ruijiang Song, Qing Fang
  • Patent number: 8615058
    Abstract: A signal acquisition system efficiently acquires a transmitted signal even at very low power. The system may synchronize to a preamble structure in the transmitted signal and, for example, determine timing parameters that locate the preamble with respect to system timing or other clock references. The system is particularly effective at acquiring weak power signals and is also robust against significant noise and other impairments, and therefore improves the ability of a receiving device that incorporates the signal acquisition system to acquire the signal and establish communication with other devices.
    Type: Grant
    Filed: September 27, 2011
    Date of Patent: December 24, 2013
    Assignee: Broadcom Corporation
    Inventors: Ka Shun Carson Pun, Siavash Ekbatani, David Ho, Siukai Mak
  • Patent number: 8486617
    Abstract: The present invention provides processes for preparing freeze-dried platelets, freeze-dried platelets made by those processes, platelets reconstituted from those freeze-dried platelets, methods of using the platelets for therapeutic, diagnostic, and research purposes, and kits comprising the freeze-dried platelets.
    Type: Grant
    Filed: August 12, 2005
    Date of Patent: July 16, 2013
    Assignee: Cellphirc, Inc
    Inventors: David Ho, Cindy S. Orser, Alan S. Rudolph, Keith Moskowitz, Joshua Dee
  • Patent number: 8426677
    Abstract: Novel gibberellin 2-oxidase (GA2ox) genes were identified. Differential expression of GA2ox genes correlated with flower development, seed germination, tiller growth and other developmental processes. In addition, the early and increased growth of tiller and adventitious root and altered root architecture caused by overexpression of GA2oxs further suggest the pleiotropic role of GA2oxs in controlling growth and architecture in plants such as rice. GA2ox5, GA2ox6 and GA2ox9 were three genes encoding class C20 GA2oxs in rice. Mutants or transgenic rice overexpressing class C20 GA2oxs exhibited a broad range of mutant phenotypes, including semi-dwarfism, increased root system and higher tiller numbers that may favor grain yield. Mutations in the conserved domain III were found to affect the physiological activity of class C20 GA2oxs. Methods are described for controlling plant growth and architecture by controlling gene expression of gibberellin 2-oxidase in the plant.
    Type: Grant
    Filed: October 23, 2009
    Date of Patent: April 23, 2013
    Assignee: Academia Sinica
    Inventors: Su-May Yu, Shuen-Fang Lo, Liang-Jwu Chen, Tuan-Hua David Ho
  • Patent number: 8416975
    Abstract: In an embodiment, a hearing aid housing is provided. The hearing aid housing may include a first behind-the-ear hearing aid housing portion, a second behind-the-ear hearing aid housing portion, and a moisture protector at least partially arranged between the first behind-the-ear hearing aid housing portion and the second behind-the-ear hearing aid housing portion.
    Type: Grant
    Filed: April 2, 2008
    Date of Patent: April 9, 2013
    Assignee: Siemens Medical Instruments Pte. Ltd.
    Inventors: Wai Kit David Ho, Wee Haw Koo
  • Publication number: 20130077722
    Abstract: A signal acquisition system efficiently acquires a transmitted signal even at very low power. The system may synchronize to a preamble structure in the transmitted signal and, for example, determine timing parameters that locate the preamble with respect to system timing or other clock references. The system is particularly effective at acquiring weak power signals and is also robust against significant noise and other impairments, and therefore improves the ability of a receiving device that incorporates the signal acquisition system to acquire the signal and establish communication with other devices.
    Type: Application
    Filed: September 27, 2011
    Publication date: March 28, 2013
    Applicant: Broadcom Corporation
    Inventors: Ka Shun Carson Pun, Siavash Ekbatani, David Ho, Siukai Mak
  • Patent number: 8394619
    Abstract: A novel beta-glucosidase and nucleic acids encoding the beta-glucosidase. Also disclosed are cells, compositions, and methods relating to using the beta-glucosidase to convert ligocellulosic material to fermentable sugars.
    Type: Grant
    Filed: January 28, 2011
    Date of Patent: March 12, 2013
    Assignee: Academia Sinica
    Inventors: Su-May Yu, Tuan-Hua David Ho, Hsion-Wen Kuo, Ng I-Son Wu, Chen-Wei Li, Yu-Ming Ju
  • Publication number: 20130059380
    Abstract: The present invention provides compositions (i.e., preservation solutions) for preserving biologies comprising at least one membrane penetrable sugar, at least one membrane impenetrable sugar, at least one anti-microbial agent, at least one anti-oxidant, adenosine, albumin, a salt, a buffer, and a chelating agent, and to methods of using such preservation solutions to preserve biologies.
    Type: Application
    Filed: February 16, 2011
    Publication date: March 7, 2013
    Applicant: HeMemics Biotechnologies, Inc.
    Inventors: David Ho, Stephen Bruttig