Abstract: Embodiments of the present disclosure relate to lipid-PEGylated solid support and phosphoramidites derivatives, methods for preparing the same, and their uses in the delivery of oligonucleotide drugs to the cellular targets.

Abstract: Antimicrobial compositions including at least one acid and at least one anionic surfactant are provided. In particular, food contact antimicrobial compositions including at least one acid and at least one anionic surfactant provide a no-rinse compositions efficacious against Norovirus, having acceptable use solution pH that do not require use of personal protective equipment (PPE), are surface compatible and do not leave residues on treated surfaces are provided. Methods of cleaning a surface with the compositions are also provided.

Abstract: An optical ferrule connector is provided. The optical ferrule connector includes a body including a beveled surface, a plurality of optical fibers embedded in the body, each of the plurality of optical fibers extending along a transmission direction and terminating in a fiber tip that is oriented coplanar to the beveled surface, and a plurality of optical elements, each optical element of the plurality of optical elements located at an associated fiber tip of an associated optical fiber, each optical element operable to manipulate or otherwise focus light into or out of a core of the associated optical fiber.

Abstract: Systems, methods, compositions of matter, and kits for undermedia repellency are disclosed. In some cases, these involve a first volume of a first liquid presented in a second volume of a second liquid above a first location of a first surface. The first liquid, second liquid, and first location can have properties sufficient to give rise to undermedia perfect liquid repellency.

Abstract: System and method for creating and managing trusted execution environments (TEEs) using different underlying hardware TEE mechanisms use a virtual secure enclave device which runs in a virtualized environment in a computer system. The device enables an enclave command transmitted to the virtual secure enclave device to be retrieved and parsed to extract an enclave operation to be executed. A TEE backend module is used to interact with a particular hardware TEE mechanism among those available in the computer system. The module ensures the enclave operation for the software process is executed by the particular hardware TEE mechanism, or the TEE scheme based on a particular hardware TEE mechanism.

Abstract: An agent engine allocates a collection of agents to scan the surface of an object model. Each agent operates autonomously and implements particular behaviors based on the actions of nearby agents. Accordingly, the collection of agents exhibits swarm-like behavior. Over a sequence of time steps, the agents traverse the surface of the object model. Each agent acts to avoid other agents, thereby maintaining a relatively consistent distribution of agents across the surface of the object model over all time steps. At a given time step, the agent engine generates a slice through the object model that intersects each agent in a group of agents. The slice associated with a given time step represents a set of locations where material should be deposited to fabricate a 3D object. Based on a set of such slices, a robot engine causes a robot to fabricate the 3D object.

Abstract: An electronic device may include an antenna and a coaxial cable coupled to the antenna. The coaxial cable may have a signal conductor coupled to an antenna resonating element of the antenna and a ground conductor coupled to an antenna ground of the antenna. The ground conductor may include an ungrounded segment that is separated from the antenna ground by a gap. A capacitive coupling between the ground conductor in the ungrounded segment and the antenna ground via the gap may form an impedance matching component for the coaxial cable. A dielectric retention layer may overlap the coaxial cable and hold the coaxial cable in place relative to the antenna ground to maintain the gap.

Abstract: The present invention relates to a four-way conversion catalyst for the treatment of an exhaust gas stream of a gasoline engine, the catalyst comprising a porous wall-flow filter substrate comprising an inlet end, an outlet end, a substrate axial length extending between the inlet end and the outlet end, and a plurality of passages defined by porous internal walls of the porous wallflow filter substrate, wherein the plurality of passages comprise inlet passages having an open inlet end and a closed outlet end, and outlet passages having a closed inlet end and an open outlet end, wherein the interface between the passages and the porous internal walls is defined by the surface of the internal walls; wherein the porous internal walls comprise pores which comprise an oxidic component comprising a first refractory metal oxide, said first refractory metal oxide comprising aluminum, said oxidic component having a platinum group metal content in the range of from 0 to 0.

Abstract: A bipolar electrosurgical device including an outer shaft, an inner shaft, first and second electrode surfaces, and an irrigation channel. The outer shaft defines a lumen, a proximal end and a distal end forming a cutting window. The inner shaft is rotatably disposed within the outer shaft, and defines a distal portion forming a cutting tip. The cutting tip and the cutting window combine to define a cutting implement. The first and second electrode surfaces are electrically isolated, and are formed at the cutting implement. The irrigation channel extends parallel to the outer shaft, and terminates in at least one outlet port. The outlet port is proximally spaced from the cutting window and is located radially outside of the outer shaft. Fluid (e.g., saline) is emitted at the exterior surface of the device near the cutting window and is readily present for interacting with the electrode surfaces.

Abstract: A switching power converter is provided that communicates with a mobile device to receive a value of a load detection current. The switching power converter adjusts the cycling of a power switch until a constant current mode of operation is entered with a known output current driving the mobile device. The switching power converter subtracts the load current from the output current to measure a soft-short circuit current.

Abstract: The present disclosure is directed to a multi-functional composition including activated carbon that is useful for injection or other application into soil or groundwater for removal (e.g., via adsorption) of inorganic contaminants in a contaminated plume. The composition of activated carbon may include physical and chemical properties to enhance the mechanism of contaminant physisorption and chemisorption including enhanced electrostatic interactions with contaminants. The multi-functional composition may further include one or more second materials (e.g., contaminant-selective agents) which comprise one or more compounds that improve the activated carbon's ability to sequester or otherwise immobilize inorganic contaminants in a subsurface environment.

Abstract: Techniques for a user interface for pathogen analysis are provided. The user interface may include an interactive dendrogram that identifies a plurality of biological samples and their corresponding sequences. The biological samples of the interactive dendrogram may be arranged based on a degree of similarity between nucleotide sequences of the biological samples. In response to a selection of biological sample, the interactive dendrogram may identify a cluster of biological samples. Each biological sample of the cluster can be identified based on a determination that a number of variations between the sequences of the biological sample and the selected biological samples are under a predefined threshold. The user interface may also include a similarity matrix that identifies a number of variations between sequences of two biological samples selected from the interactive dendrogram.

Abstract: Oral care based imaging computer-implemented systems and methods for analyzing attributes of a facial image portion of at least one person depicted in a digital image. An oral care digital imaging computer-implemented method for analyzing a facial image portion of a person depicted in a digital image may include analyzing the facial image portion for positive and negative attributes as defined by pixel data of the digital image and generating a probability value based on the positive and negative attributes in the facial image portion in the digital image.

Abstract: Provided are methods, kits and compositions related to toxicity associated with administration of cell therapy for the treatment of diseases or conditions, e.g., cancer, including methods for use in predicting and treating a toxicity. In some embodiments, the toxicity is a neurotoxicity or cytokine release syndrome (CRS), such as a severe neurotoxicity or a severe CRS. The methods generally involve detecting a parameter of a biomarker or individually a parameter of each biomarker in a panel of biomarkers, such as a concentration, amount or activity, and comparing the detected parameter to a reference value for the parameter to determine if the subject is at risk for developing the toxicity, such as neurotoxicity or CRS or severe neurotoxicity or severe CRS.

Abstract: The present invention relates generally to stable percarboxylic acid compositions comprising, inter alia, at least two stabilizing agents, and various uses for water treatments, including water treatments in connection with oil- and gas-field operations. The present invention also relates to slick water compositions and gel based compositions that comprise stable percarboxylic acid compositions and the use thereof in oil- and gas-field operations.

Abstract: Antimicrobial compositions including at least one acid and at least one anionic surfactant are provided. In particular, food contact antimicrobial compositions including at least one acid and at least one anionic surfactant provide efficacious virucidal activity, including against Norovirus, having acceptable use solution pH that do not require use of personal protective equipment (PPE), are surface compatible and do not leave residues on treated surfaces. Methods of cleaning a surface with the compositions are also provided and may beneficially eliminate the need to rinse the antimicrobial compositions after use.

Abstract: Rechargeable batteries include a NiyFe1-y cathode where 0?y?1, an anode comprising a current collector, a porous separator positioned between the cathode and the anode, and an electrolyte comprising MAlX4, wherein M is Na, Li, K, or a combination thereof, and X is Cl, Br, I, or a combination thereof, and wherein the electrolyte is a solid at temperatures less than 50° C. The batteries are temperature activated. The electrolyte temperature is increased above its melting point while charging and reduced below the melting point for energy storage, such as seasonal energy storage. The electrolyte temperature is increased above the melting point again to discharge the battery.

Abstract: A thermally sensitive ionic redox transistor comprises a channel, a reservoir layer, and an electrolyte layer disposed between the channel and the reservoir layer. A conductance of the channel is varied by changing concentration of ions in the channel layer. The electrolyte layer is configured to undergo a state change at a state transition temperature. Below the state transition temperature, ions in the electrolyte layer are substantially immobile. Above the state transition temperature, ions can move freely between the reservoir layer and the channel across the electrolyte layer in response to a voltage being applied between the channel and the reservoir layer. When the device is cooled below the state transition temperature or temperature range, the ions are trapped in one or more of the layers because the electrolyte layer loses its ionic conductivity. A state of the redox transistor can be read by measuring the conductance of the channel.

Abstract: The present invention relates to compositions of peptide inhibitors of the interleukin-23 receptor (IL-23R) or pharmaceutically acceptable salt or solvate forms thereof, corresponding pharmaceutical compositions, methods and/or uses for treatment of autoimmune inflammation and related diseases and disorders.

Abstract: Various embodiments are disclosed for providing machine learning routines with peripheral device data to infer driver activity and location. Peripheral device data may be collected on a peripheral device having a machine learning routine executing thereon to infer driver activity and perform improved estimation of driver location. Using driver activity and location estimation, contextually relevant delivery workflow assistance may be automatically provided to a delivery driver or other individual without requiring manual input, thereby improving driver safety and operational efficiency.