Abstract: Systems and methods for accurate measurement and transmission of water level parameters during weather events, such as floods, are provided. The solid-state system can effectively measure water level without utilizing moving parts, pumps, or floats and may implement an improved water level determination method that compensates for inherent sources of error. Additionally, the system may be comprised of a network of sensor units that can communicate weather measurements wirelessly via a hybrid mesh network consisting variously of wireless terrestrial radio, cellular, and satellite communication links. By doing so, the status of water level and other environmental parameters may be reported in real time to first responders and emergency planners.

Abstract: A Honeybee Swarm Trap to provide an inexpensive but sturdy bee box for keeping bees that is flexible in its application. To propagate beehives a beekeeper commonly uses a swarm catcher. These swarm catchers are placed near existing beehives, typically those naturally occurring, a swarm trap may be placed near the location of original beehive. Scout bees can visit the swarm trap and assess the trap for a swarm or propagated swarm to take up residence. Once the honeybee swarm take up residence in the swarm trap, the beekeeper can move the swarm to another location to house the honeybee colony.

Abstract: An electronic contact lens. The electronic contact lens includes an energy storage device and a charging circuit for charging the energy storage device. The electronic contact lens is configured to disable the charging circuit when the contact lens is worn.

Abstract: A method, system, apparatus, and/or device that may include: a first sensor operable to take a first physiological measurement; a second sensor operable to take a second physiological measurement; and a processing device operatively coupled to the first sensor and the second sensor. The processing device may be operable to: receive a first measurement data for the first physiological measurement; receive a second measurement data for the second physiological measurement; generate an event data set based on the first measurement data with the second measurement data; determine an event occurred based on the event data set; determine a type of the event; and in response to the event being a safety event: determine a type of the safety event; identify a risk level of the safety event; and in response to the risk level exceeding a threshold level, notify a second device of the safety event.

Abstract: A method, system, apparatus, and/or device to determine a condition of a user using a wearable device with a miniaturized spectrometer. The method, system, apparatus, and/or device may include: a band configured to extend at least partially around a body part of a user, the body part comprising an internal feature within the body part; a light source embedded in the band, where the light source is configured to emit light into the body part as the user wears the band; a collimator; an optical filter; and an optical sensor, where the collimator, optical sensor, or the optical filter are arranged together to form a stack embedded in the band.

Abstract: The present invention relates to compounds of formula (I): wherein Q is selected from O or S; R1 is a non-aromatic heterocyclic group comprising at least one ring nitrogen atom, wherein R1 is attached to the sulfur atom of the sulfonylurea group by a ring carbon atom, and wherein R1 may optionally be substituted; and R2 is a cyclic group substituted at the ?-position, wherein R2 may optionally be further substituted. The present invention further relates to salts, solvates and prodrugs of such compounds, to pharmaceutical compositions comprising such compounds, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by the inhibition of NLRP3.

Abstract: A novel food station comprises a plurality of cubbies sized to enclose food portion containers, and an externally accessible collection hatch. An internal transport system uses an end effector to temporarily couple to a portion container carrier of a selected cubby, and to controllably move the food portion container carrier within the food station from the selected cubby to the collection hatch. The food station includes heating and cooling systems that selectively provide or remove heat to or from each of the plurality of cubbies independently of the other cubbies, with a heating or cooling rate, or for a heating or cooling duration, that is independently scheduled and controllable for each of the plurality of cubbies.

Abstract: The present invention relates to substituted5-membered nitrogen containing heteroaryl compounds, such as triazole esters, where the heteroaryl ring is further substituted via a linking group such as —NH— with a cyclic group which in turn is substituted at the a-position. The present invention further relates to associated salts, solvates, prodrugs and pharmaceutical compositions, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by NLRP3 inhibition.

Abstract: The present invention relates to macrocyclic compounds, such as macrocyclic sulfonyl ureas. The present invention further relates to associated salts, solvates, prodrugs and pharmaceutical compositions and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by NLRP3 inhibition.

Abstract: A medical manipulation assembly includes a catheter and distal and proximal steering mechanisms. The catheter includes distal and proximal steerable portions with working channels configured to receive an instrument. The distal steering mechanism is operable to bend the distal steerable portion in a first plane relative to the proximal steerable portion in response to movement of a first portion of the distal steering mechanism about a first axis of rotation and to bend the distal steerable portion in a second plane relative to the proximal steerable portion in response to movement of a second portion of the distal steering mechanism about a second axis of rotation. The proximal steering mechanism is operable to bend the proximal steerable portion by rotational movement of the proximal steering mechanism. Distal pullwires extend between the distal steerable portion and steering mechanism and proximal pullwires extend between the proximal steerable portion and steering mechanism.

Abstract: Various embodiments of the present disclosure relate generally to systems and methods for generating multi-view interactive digital media representations in a virtual reality environment. According to particular embodiments, a plurality of images is fused into a first content model and a first context model, both of which include multi-view interactive digital media representations of objects. Next, a virtual reality environment is generated using the first content model and the first context model. The virtual reality environment includes a first layer and a second layer. The user can navigate through and within the virtual reality environment to switch between multiple viewpoints of the content model via corresponding physical movements. The first layer includes the first content model and the second layer includes a second content model and wherein selection of the first layer provides access to the second layer with the second content model.

Abstract: A method for the purification of albumin from plasma is described. The method comprises (a) contacting the plasma with sodium caprylate (NaCP) at an amount dependent on total protein concentration and the ratio of NaCP to total protein in the plasma, (b) heating the plasma at a near neutral pH range, and (c) separating the albumin from non-albumin-phase. The said method provides for a high yield and purity albumin solution.

Abstract: Systems, methods, and devices of a health device network may include: a non-invasive glucometer that non-invasively measures analyte levels; an invasive glucometer communicatively coupled directly to the non-invasive glucometer; a cloud-based server communicatively coupled to the non-invasive glucometer or the invasive glucometer; a user device communicatively coupled to the cloud-based server; and/or a user interface that displays the invasive glucose measurement, the non-invasive glucose measurement, a data batch, and/or processed data to the user. The non-invasive glucometer and/or the invasive glucometer may aggregate an invasive glucose measurement and a non-invasive glucose measurement into the data batch.

Abstract: A system and a method for controlling an electronic device embedded in a package of a consumer product are disclosed. In one aspect, the consumer product packaging includes a bottle for a beverage, a memory, a receiver and a circuit. The memory stores an action to be performed in response to an input. The receiver receives the input indicative of movement of the bottle. The circuit retrieves the action stored in memory upon receipt of the input and command an electronic communication module to perform the action at a particular time or in a particular sequence.

Abstract: According to examples, a machine may include a base housing and a handle assembly mounted to the base housing and extending at an angle from the base housing along a handle plane. The handle assembly may include a mating component having a plurality of slots arranged at multiple angular positions along a slot plane, the slot plane being parallel to the handle plane. The mating assembly may also include a handle segment rotatably mounted to the mating component, the handle segment housing a locking member, in which the handle segment is rotatable along the slot plane relative to the base housing and the locking member is removably insertable into a first slot of the plurality of slots when the handle segment is in a first angular position and is removably inserted into a second slot of the plurality of slots when the handle segment is in a second angular position.

Abstract: The present invention relates to compounds of formula (I): wherein Q is O or S, R1 is a 6-membered heteroaryl group containing at least one nitrogen atom in the 6-membered ring structure, wherein R1 may optionally be substituted, and R2 is a cyclic group substituted at the ?-position, wherein R2 may optionally be further substituted. The present invention further relates to salts, solvates and prodrugs of such compounds, to pharmaceutical compositions comprising such compounds, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by the inhibition of NLRP3.

Abstract: The present invention provides novel liposomes comprising Gd.DOTA.DSA (gadolinium (III) 2-{4,7-bis-carboxymethyl-10-[(N,N-distearylamidomethyl-N?-amido-methyl]-1,4,7,10- =tetra-azacyclododec-1-yl}-acetic acid), characterised in that the liposome further comprises a neutral, fully saturated phospholipid component (e.g. DSPC (1,2-distearoyl-sn-glycero-3-phospocholine]), which are of particular use in the preparation of magnetic resonance contrast agents for enhancing a magnetic resonance image of tumours in a mammal.

Abstract: The present invention relates to compounds of formula (I): wherein Q is selected from O or S; R1 and R3 are each independently hydrogen or an optionally substituted hydrocarbyl group, or R1 and R3 together with the nitrogen atom to which they are attached may form a 3- to 12-membered optionally substituted cyclic group; and R2 is a cyclic group substituted at the position, wherein R2 may optionally be further substituted. The present invention further relates to salts, solvates and prodrugs of such compounds, to pharmaceutical compositions comprising such compounds, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by the inhibition of NLRP3.