Abstract: This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.

Abstract: An identity and access management (IAM) system is associated with a set of data sources from which data is collected. A set of vulnerabilities that the IAM system should attempt to detect is identified. For each vulnerability to be detected, a prioritized list of strategies used to detect that vulnerability is generated. Preferably, each strategy specifies the type(s) of data required to detect that vulnerability. An algorithm to determine a best strategy to be used for detecting each vulnerability, preferably based on the data available from the data sources, is then identified. The IAM system then collects data in an optimized manner. In particular, during the collection process, the IAM system preferably collects only what is necessary based on the configuration, even if the data source is capable of providing additional data. The collected data is then processed to detect security vulnerabilities associated with the IAM accounts.

Abstract: The present disclosure provides regioselective methods for synthesizing intermediates useful in making prostacyclin derivatives, such as treprostinil.

Abstract: This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.

Abstract: A method for assessing security risks associated with a cloud application to which one or more connected applications are coupled begins by configuring a security risk assessment application to function as a connected application. The security risk assessment application collects “first” data associated with one or more accounts, and “second” data associated with the one or more connected applications coupled to the cloud application. After receiving the first and second data, the security risk assessment application instantiates that data into a generic “data object” that the system uses to represent each account and each of the connected applications. Each such data object thus is populated either with the first data or the second data, depending on whether the data object represents an account or a connected application. A risk assessment is then applied to the generic data object to assess a security risk associated with the cloud application.

Abstract: A method of provisioning a plurality of applications from different application developer systems to a network provider system comprises establishing a plurality of service accounts for a corresponding plurality of application service provider systems, receiving a plurality of API interfaces from the plurality of application service provider systems, integrating, by the processor system, each of the plurality of API interfaces with a unified services platform API interface, receiving a provider API interfaces for a network provider system, and integrating the provider API interface with the unified services platform API interface. The plurality of application service provider systems provide services for use in association with a telephone number of a subscriber of telecommunication services. At least two of the API interfaces are different, and at least one of the plurality of API interfaces from the plurality of application service provider systems is not compatible with the provider API interface.

Abstract: The present disclosure provides regioselective methods for synthesizing intermediates useful in making prostacyclin derivatives, such as treprostinil.

Abstract: This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.

Abstract: A system and method for aggregating services within a VoIP network. The VoIP network comprises a plurality of vendors, resellers, and users, and each reseller aggregates a plurality of services from the vendors and other resellers. Each type of service may be organized into two or more tiers, with each tier including one or more services. Each tier is presented to downstream users as a single price and is re-branded with the reseller's branding elements. Downstream users can select a desired service from a given tier, and the tier may automatically select a service that maximizes the profit for the reseller.

Abstract: A surgical clip applier having an adjustable jaw open dimension, including an instrument body having jaws at a distal end and an actuator at a proximal end; an actuator shaft movable longitudinally relative to the instrument body to transmit actuating force from the actuator to the jaws; and an adjusting member threadedly engaged with the actuator shaft and configured to engage the instrument body at a jaw open position, wherein rotation of the adjusting member relative to the actuating shaft moves the adjusting member longitudinally relative to the actuating shaft to adjust a jaw open position of the jaws when the adjusting member contacts the instrument body.

Abstract: This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.

Abstract: This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.

Abstract: The present invention is directed to a novel method for preparing a synthetic intermediates for treprostinil. Also described are methods of preparing treprostinil comprising utilizing novel intermediates described herein as well as novel intermediates useful for synthesis prostacyclin derivatives, such as treprostinil.

Abstract: A wearable aid for gripping an item by hand includes a main body shaped to be worn by a user, a strap connected to a first location of the main body and a releasable retaining means at a second location of the main body that is away from the first location. When a user wearing the aid has engaged an item to be gripped, part of the strap can be passed over at least part of one or more fingers of the user's hand and secured to the releasable retaining means in a manner that aids the user in gripping the item.

Abstract: The present invention is directed to a novel method for preparing a synthetic intermediates for treprostinil. Also described are methods of preparing treprostinil comprising utilizing novel intermediates described herein as well as novel intermediates useful for synthesis prostacyclin derivatives, such as treprostinil.

Abstract: This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.

Abstract: A system and method for aggregating services within a VoIP network. The VoIP network comprises a plurality of vendors, resellers, and users, and each reseller aggregates a plurality of services from the vendors and other resellers. Each type of service may be organized into two or more tiers, with each tier including one or more services. Each tier is presented to downstream users as a single price and is re-branded with the reseller's branding elements. Downstream users can select a desired service from a given tier, and the tier may automatically select a service that maximizes the profit for the reseller.

Abstract: This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.

Abstract: This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.