Abstract: This invention provides a device for delivering medical implants, the device comprising a guide, a mandrel disposed internal to the guide, and a sleeve, wherein the sleeve is disposed external to the guide and is attached to the mandrel for movement therewith relative to the guide. Included among the various embodiments are devices configured for abutting a proximal surface against the palm of a user and presenting finger tabs for retraction of the guide relative to the mandrel. Optionally, a device of the present invention is a dual-mode device configured for being operated independently in each of an ejection mode and an injection mode. Optionally, a device of the present invention is configured for delivering an implant to the eye of a subject. Optionally, the eye implant is a retinal implant. Optionally, the implant comprises retinal cells.

Abstract: Devices, systems, and methods for performing injections with lowered likelihood of infection include needles and other injection means with protective sleeves or sheaths. The protective sleeve can protect the needle before, during, or before and during an injection. The force needed to administer an injection or penetrate an insertion site using an injection device or system with a protective sleeve can be about the same to up to 50% more than the force needed for a system or device without a protective sleeve. The force needed to collapse the protective sleeve can be less than 100 gram-force. The material, the thickness, or both the material and the thickness of the protective sleeve may differ when comparing the portion of the sleeve near the needle tip and the portion near the base of the needle.

Abstract: This invention provides a device for delivering substances such as medical implants and tissues. The device comprises a mandrel and a mandrel guide whereby substances are delivered by retracting the mandrel guide relative to the mandrel. Included among the various embodiments are devices specialized for delivering retinal pigment epithelial (RPE) cells or nanoplates containing RPE cells to the retina, devices with precise control of delivery, devices with specialized mandrels and/or nozzles, and multifunctional devices adapted to provide additional functions such as infusion and/or suction, illumination, and diathermy.

Abstract: Devices, systems, and methods for performing injections with lowered likelihood of infection include needles and other injection means with protective sleeves or sheaths. The protective sleeve can protect the needle before, during, or before and during an injection. The force needed to administer an injection or penetrate an insertion site using an injection device or system with a protective sleeve can be about the same to up to 50% more than the force needed for a system or device without a protective sleeve. The force needed to collapse the protective sleeve can be less than 100 gram-force. The material, the thickness, or both the material and the thickness of the protective sleeve may differ when comparing the portion of the sleeve near the needle tip and the portion near the base of the needle.

Abstract: This invention provides a device for delivering substances such as medical implants and tissues. The device comprises a mandrel and a mandrel guide whereby substances are delivered by retracting the mandrel guide relative to the mandrel. Included among the various embodiments are devices specialized for delivering retinal pigment epithelial (RPE) cells or nanoplates containing RPE cells to the retina, devices with precise control of delivery, devices with specialized mandrels and/or nozzles, and multifunctional devices adapted to provide additional functions such as infusion and/or suction, illumination, and diathermy.

Abstract: A variable-rigidity, small-gauge illuminator is disclosed, one embodiment being a small-gauge illumination surgical system comprising: a light source for providing a light beam; an optical cable, optically coupled to the light source for receiving and transmitting the light beam; a handpiece, operably coupled to the optical cable; an optical fiber, operably coupled to the handpiece, wherein the optical fiber is optically coupled to the optical cable to receive and transmit the light beam to illuminate an area; and a cannula, operably coupled to the handpiece, for housing and directing the optical fiber, wherein the cannula is operable to extend and retract from the handpiece to vary the length of the cannula extending from the handpiece, and wherein the optical fiber is operably connected to the cannula.

Abstract: A variable intensity endoilluminator system is disclosed, one embodiment comprising: a light source for providing a light beam; an optical cable, optically coupled to the light source for receiving and transmitting the light beam; a handpiece, operably coupled to the optical cable to receive the light beam; an optical fiber, operably coupled to the handpiece, wherein the optical fiber is optically coupled to the optical cable to receive and transmit the light beam to illuminate a surgical field; and a translucent cannula, operably coupled to the handpiece, for housing and directing the optical fiber, wherein the cannula is operable to diffuse and transmit the light from the light beam when the optical fiber is retracted into the cannula. The cannula and the handpiece can be fabricated from biocompatible materials.

Abstract: A transparent illuminated infusion cannula is provided for illuminating an area during eye surgery. An optical fiber may be spaced a certain distance away from the cannula such that fluid flow around the distal end of the fiber and into the transparent cannula may occur with a much higher flow rate than what had previously been possible. The fiber cannula airspace may be optimized so that the cross-sectional area of the fluid conduit remains substantially constant in order to achieve a best compromise between high light transmittance and high fluid flow rate.

Abstract: A variable intensity endoilluminator system is disclosed, one embodiment comprising: a light source for providing a light beam; an optical cable, optically coupled to the light source for receiving and transmitting the light beam; a handpiece, operably coupled to the optical cable to receive the light beam; an optical fiber, operably coupled to the handpiece, wherein the optical fiber is optically coupled to the optical cable to receive and transmit the light beam to illuminate a surgical field; and a translucent cannula, operably coupled to the handpiece, for housing and directing the optical fiber, wherein the cannula is operable to diffuse and transmit the light from the light beam when the optical fiber is retracted into the cannula. The cannula and the handpiece can be fabricated from biocompatible materials.

Abstract: A disposable injection device has a dispensing chamber housing and a plunger. The dispensing chamber housing has an inner surface and an outer surface. The inner surface partially defines a dispensing chamber for receiving a quantity of a substance. The plunger is engaged with the inner surface of the dispensing chamber housing, is capable of sliding in the dispensing chamber housing, and is fluidly sealed to the inner surface of the dispensing chamber housing. The plunger has a plunger interface. The plunger interface mates with a mating surface on a mechanical linkage interface such that force is transferred from the mechanical linkage interface to the plunger along a first direction towards the plunger when the plunger interface is in contact with the mating surface of the mechanical linkage interface, and force is not substantially transferred from the mechanical linkage interface to the plunger along a second direction away from the plunger.

Abstract: A variable-rigidity, small-gauge illuminator is disclosed, one embodiment being a small-gauge illumination surgical system comprising: a light source for providing a light beam; an optical cable, optically coupled to the light source for receiving and transmitting the light beam; a handpiece, operably coupled to the optical cable; an optical fiber, operably coupled to the handpiece, wherein the optical fiber is optically coupled to the optical cable to receive and transmit the light beam to illuminate an area; and a cannula, operably coupled to the handpiece, for housing and directing the optical fiber, wherein the cannula is operable to extend and retract from the handpiece to vary the length of the cannula extending from the handpiece, and wherein the optical fiber is operably connected to the cannula such that the distal end of the optical fiber and the distal end of the cannula remain co-incident as the length of the cannula extending from the handpiece is varied.

Abstract: A transparent illuminated infusion cannula is provided for illuminating an area during eye surgery. An optical fiber may be spaced a certain distance away from the cannula such that fluid flow around the distal end of the fiber and into the transparent cannula may occur with a much higher flow rate than what had previously been possible. The fiber cannula airspace may be optimized so that the cross-sectional area of the fluid conduit remains substantially constant in order to achieve a best compromise between high light transmittance and high fluid flow rate.

Abstract: A thin walled, hubbed cannula with an exterior diameter of approximately that of a 20 gauge surgical instrument and in interior bore having a diameter that is slightly larger than a 23 gauge or 25 gauge surgical instrument. The scleral contact surface of the hub of the adapter also can be rounded to provide a pivot point for the surgical instrument shaft, thereby reducing bending forces on the relatively thin shaft of the instrument.

Abstract: A syringe-like device having a chamber in which a pressurizing piston reciprocates. The chamber is connected on one end to a vial containing a drug to be delivered to an eye and on the other end to a needle or cannula for administering the drug to an eye. Pulling proximally backwards on the piston creates a vacuum in the chamber and draws the drug out of the vial. Upon release of the piston, a spring pushes the piston forward, pressurizing the chamber and forcing the drug out of the cannula. A one-way valve prevents the drug from being expelled back into the vial. A pinch valve between the chamber and the cannula allows the flow of the drug out of the cannula to be stopped. The flow rate of the drug out of the cannula can be controlled by varying the size of the chamber, piston and spring.

Abstract: A device having a pair of stretcher bars. The first bar remains fixed while the second bar can be reciprocated relative to the first bar by actuation of a movable slide. The device of the present invention is useful for stretching and implanting the ring portion of a two component intraocular lens.

Abstract: A variable-intensity, wide-angle illuminator is disclosed, one embodiment comprising: a light source for providing a light beam; an optical cable, optically coupled to the light source for receiving and transmitting the light beam; a handpiece, operably coupled to the optical cable to receive the light beam; an optical fiber, operably coupled to the handpiece, wherein the optical fiber is optically coupled to the optical cable to receive and transmit the light beam; an optical element, optically coupled to a distal end of the optical fiber, for receiving the light beam and scattering the light beam to illuminate a surgical field, wherein the optical element comprises a hemispherically shaped sapphire; and a cannula, operably coupled to the handpiece, for housing and directing the optical fiber and the optical element.

Abstract: An assembly of connectors adapt multiple optic fiber illuminators of microsurgical instruments for use with a variety of different available light sources.

Abstract: A micro surgical lighting instrument includes a hollow needle and a light guide received coaxially within the hollow needle and connected to a light source for transmitting light to a surgical site of a patient. The light guide has a distal end formed with an end face of circular segment shape and defined by a plane oriented orthogonal to the axis of the hollow needle, and a slanted surface adjacent the end face and extending rearwardly at an acute angle, with the slanted surface being lined by a coating for reflection of incident light rays.

Abstract: A control unit may be mounted in operative relationship to a conventional tonometer adjustment wheel to allow for motorized adjustment thereof. The unit includes a battery which powers a DC motor. The motor provides driven input to a right-angle gear drive, the output of which drives a friction wheel. The friction wheel is positioned so as to be in frictional engagement with the outer circumferential surface of the tonometer adjustment wheel. Actuation of a remote-mounted switch therefore allows the attending ophthalmologist to selectively drive the tonometer adjustment wheel in clockwise and counterclockwise directions so as to thereby adjust tonometer settings. The gear drive is mounted for pivotal movements about an axis transverse to the rotational axis of the tonometer adjustment wheel so that the friction wheel may be moved between engaged and disengaged positions relative to the tonometer adjustment wheel.

Abstract: Rotary oscillatory coupling includes a pair of opposed hubs which are independently rotatable about a common axis. Pairs of permanent magnets are provided in the opposed faces of the hubs. The proximal hub is continuously rotated in a selected rotational direction by a suitable motor. During a portion of the proximal hub's rotation, the distal hub will concurrently be rotated by virtue of the magnetic field interaction that occurs between the magnet pairs. The distal hub is, however, prevented from rotating a complete cycle by virtue of a mechanical stop. Upon encountering the mechanical stop, the rotation direction of the distal hub will be reverse to that of the continuously rotating proximal hub. When the magnets of the proximal and distal hubs again are in proximity to one another, the distal hub will then experience another reversal of rotation direction so that it rotates in the same direction as the proximal hub.