Abstract: The present disclosure provides binding proteins, such as antibodies and antigen-binding fragments, which specifically bind to human IL-36 cytokines, IL-36?, IL-36?, and/or IL-36?, and block the IL-36 stimulated signaling pathways. Compositions comprising such binding proteins and methods of making and using such binding proteins are also provided.

Abstract: A three-terminal bidirectional GaN FET with a single gate. The device is formed by integrating a single-gate bidirectional GaN FET in parallel with a bidirectional device formed of two back-to-back GaN FETs with a source that is connected to the field plate of the device and does not have a pin-out. Diodes or gate-shorted-to-source FETs are connected between the source without pin-out and the D/S and S/D power terminals of the device. In another embodiment, a single-gate bidirectional GaN FET is provided with diodes or gate-shorted-to-source FETs connected between the substrate and the power terminals of the device.

Abstract: A method includes attaching a first portion of a preformed metal micro-wire to a multilayer structure. The preformed metal micro-wire has a diameter of 10 microns or less. The method also includes attaching a second portion of the preformed metal micro-wire to the multilayer structure.

Abstract: Provided is a Fluid Catalytic Cracking catalyst additive composition and method of making the same. The catalyst additive composition comprises zeolite about 35 wt % to about 80 wt %, preferably about 40 wt % to about 70 wt %; silica about 0 wt % to about 10 wt %, preferably about 2 wt % to about 10 wt %; about 10.5 wt % to 20 wt % alumina and about 7 wt % to 20 wt % P2O5, preferably about 11 wt % to about 18 wt %, and the balance clay which can fall between 0 and 50 wt %. The alumina is typically derived from more than one source, such as at least an amorphous or small crystallite size pseudo-boehmite alumina and then either a large crystallite size alumina or other reactive alumina.

Abstract: A scrubbing tool for cleaning a surface that has a handle for holding by a user in a cleaning operation. The handle has a first connector. The scrubbing tool also has a cleaning head having a second connector configured to mate with the first connector in order to attach the cleaning head to the handle in an engaged position. The cleaning head is comprised entirely of a material configured to dissolve in water and has a cleaning agent.

Abstract: A display may have a pixel array such as a liquid crystal pixel array. The pixel array may be illuminated with backlight illumination from a direct-lit backlight unit. The backlight unit may include an array of light-emitting diodes (LEDs) on a printed circuit board. The display may have a notch to accommodate an input-output component. Reflective layers may be included in the notch. The backlight may include a color conversion layer with a property that varies as a function of position. The light-emitting diodes may be covered by a slab of encapsulant with recesses in an upper surface.

Abstract: Techniques are disclosed herein for integrating document question answering in an artificial intelligence-based platform, such as a chatbot system. The techniques include receiving a query from a user, rewriting the query to include one or more specific descriptors, computing an embedding vector for the rewritten query, retrieving one or more textual passages from a document store utilizing the embedding vector for the rewritten query, determining one or more answers to the rewritten query within the one or more textual passages, and returning the one or more answers.

Abstract: Described herein are methods and computer systems for classification of CD8 T-cell topology using a patient response-based linear cutoff model. A plurality of histology images of tissue samples in a plurality of patients are received by a computer system. An image analysis of the plurality of histology images is performed to obtain a CD8+ T-cell abundance in the tumor parenchyma and stroma in each of the plurality of histology images. Real inflammation scores and tumor infiltration scores are determined based on a polar coordinate transformation of the CD8+ T-cell abundance in the tumor parenchyma and stroma. Based on the real inflammation scores and tumor infiltration scores, a feature space is generated, and linear boundaries or linear cutoffs between a plurality of classifications in the feature space are identified based on the real inflammation scores, the tumor infiltration scores, and patient response data.

Abstract: An agricultural navigation system and method for an autonomous vehicle (AV) is described. The agricultural navigation system includes a system controller, a localization module associated with the system controller, and an environmental sensor. The system controller determines an AV positional pose that identifies the location of the AV. The system controller determines a relative body frame of reference (RBF) that is associated with the AV positional pose. The environmental sensor detects an asset feature in the AV environment. The asset feature includes an agricultural asset feature having a crop row. The system controller identifies at least one asset feature frame (AFF) that includes a coordinate system originating at the asset feature. The localization module determines the AV positional pose in the coordinate system of the AFF. The system controller transforms the AV positional pose from the RBF coordinate system to the coordinate system of the AFF.

Abstract: A tool system for installing a parking pawl includes a tool that includes a base, a plate, and an actuator. The base includes a base surface configured to support a parking pawl in a predetermined position. The plate includes a protrusion that extends upward from a front portion of the plate. A rear portion of the plate is coupled to a front portion of the base. The plate is movable relative to the base between a retention position in which the protrusion is positioned to retain a pawl spring loaded on the parking pawl in a pretensioned state, and a release position in which the protrusion is configured to release the pawl spring. The actuator is operably coupled to the plate such that activation of the actuator moves the plate between the retention position and the release position.

Abstract: Computer implemented techniques for converting a text string to an interactive media. The techniques cause a data processing system to receive a text string having one or more branching moments, process the text string to recognize indications of the one or more branching moments given the text string, convert the processed text string and the indications of the one or more branching moments into executable computer code, receive a response to a given one of the converted one or more branching moments from a predetermined set of responses, generate, from the executable computer code and media elements for the response, a virtual respondent, and store the executable computer code and the media elements as a file in the computer storage that represents the virtual respondent.

Abstract: An Autonomous Vehicle (AV) system is described. The AV system is capable of determining at motor control command associated with an AV trajectory. The AV system includes a content generating device, a system controller, and an AV sensor. The content generating device collects target data associated with a target. The system controller is communicatively coupled to the content generating device. The system controller extracts target features from the target data. Also, the system controller compares the extracted target features to target model data to determine a target pose. Additionally, the system controller determines the AV trajectory by comparing the target pose with at least one target objective. The AV sensor determines an AV state. The system controller determines a motor control command associated with the AV trajectory based on the AV state, the target objective, and the AV trajectory.

Abstract: A scrubbing tool for cleaning a surface that has a handle for holding by a user in a cleaning operation. The handle has a first connector. The scrubbing tool also has a cleaning head having a second connector configured to mate with the first connector in order to attach the cleaning head to the handle in an engaged position. The cleaning head is comprised entirely of a material configured to dissolve in water and has a cleaning agent.

Abstract: A catalyst structure includes: (1) a substrate; (2) a catalyst layer on the substrate; and (3) an adhesion layer disposed between the substrate and the catalyst layer. In some implementations, an average thickness of the adhesion layer is about 1 nm or less. In some implementations, a material of the catalyst layer at least partially extends into a region of the adhesion layer. In some implementations, the catalyst layer is characterized by a lattice strain imparted by the adhesion layer.

Abstract: A fluid catalytic cracking unit fractionator comprising a fractionator column having a slurry pumparound section and a bottom liquid section. The slurry pumparound section comprises an upper bed and a lower bed each disposed in the fractionator column. The slurry pumparound section further comprises an upper liquid distributor (such as a spray header comprising a plurality of upper nozzles) disposed above the upper bed and configured to distribute liquid from the bottom liquid section onto the upper bed. The slurry pumparound section also comprises a lower liquid distributor (such as a spray header comprising a plurality of lower nozzles) disposed below the upper bed and above the lower bed and configured to distribute liquid from the bottom liquid section onto the lower bed.

Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a user equipment (UE) may receive configuration information identifying a set of possible paging occasions and a set of connected mode communications. The UE may receive paging in a paging occasion, of the set of possible paging occasions, for which there is not a collision between the paging occasion and the set of connected mode communications and that is selected from the set of possible paging occasions based at least in part on a power utilization characteristic. Numerous other aspects are described.

Abstract: The invention provides anti-KLK7 antibodies, anti-KLK5 antibodies, anti-KLK5/KLK7 multispecific antibodies, and methods of using the same.

Abstract: A fluid catalytic cracking unit fractionator comprising a fractionator column having a slurry pumparound section and a bottom liquid section. The slurry pumparound section comprises an upper bed and a lower bed each disposed in the fractionator column. The slurry pumparound section further comprises an upper liquid distributor (such as a spray header comprising a plurality of upper nozzles) disposed above the upper bed and configured to distribute liquid from the bottom liquid section onto the upper bed. The slurry pumparound section also comprises a lower liquid distributor (such as a spray header comprising a plurality of lower nozzles) disposed below the upper bed and above the lower bed and configured to distribute liquid from the bottom liquid section onto the lower bed.