Patents by Inventor Elisabeth Perzborn

Elisabeth Perzborn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted oxazolidinones and their use in the field of blood coagulation
    Patent number: 7576111
    Abstract: The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: August 18, 2009
    Assignee: Bayer Schering Pharma AG
    Inventors: Alexander Straub, Thomas Lampe, Jens Pohlmann, Susanne Rohrig, Elisabeth Perzborn, Karl-Heinz Schlemmer, Joseph Pernerstorfer
  • Substituted 2-thio-3,5-dicyano-4-aryl-6-aminopyridines and their use
    Patent number: 7504421
    Abstract: The invention relates to compounds of general formula (I), a method for the production thereof and the use thereof as pharmacologically effective substances for a broad medical indication spectrum. Furthermore, selective adenosine receptor ligands, preferably selective adenosine A1-, adenosine A2a- and/or adenosine A2b-receptor ligands are provided for the prophylaxis and/or the treatment of diseases, especially cardiovascular diseases, diseases of the urogenital region, diseases of the respiratory tract, inflammatory and neuroinflammatory diseases, diabetes, especially pancreatic diabetes, neurodegenerative diseases, pain states, cancer as well as liver fibrosis and liver cirrhosis.
    Type: Grant
    Filed: February 21, 2006
    Date of Patent: March 17, 2009
    Inventors: Ulrich Rosentreter, Rolf Henning, Marcus Bauser, Thomas Krämer, Andrea Vaupel, Walter Hübsch, Klaus Dembowsky, Olga Salcher-Schraufstatter, Johannes-Peter Stasch, Thomas Krahn, Elisabeth Perzborn
  • 2-Aminoethoxyacetic Acid Derivatives and Their Use
    Publication number: 20090036504
    Abstract: The present application relates to novel 2-aminoethoxyacetic acid derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular thromboembolic disorders.
    Type: Application
    Filed: September 14, 2006
    Publication date: February 5, 2009
    Applicant: BAYER HEALTHCARE AG
    Inventors: Christian R. Thomas, Susanne Rohrig, Elisabeth Perzborn
  • Substituted isoindoles and their use
    Patent number: 7482472
    Abstract: The invention relates to coagulation of the blood. Disclosed are novel compounds of formula (I), a method for the production of these compounds, pharmaceutical compositions containing them, and methods of using them for the prevention and/or treatment of various diseases.
    Type: Grant
    Filed: March 12, 2007
    Date of Patent: January 27, 2009
    Assignee: Bayer Healthcare AG
    Inventors: Alexander Straub, Thomas Lampe, Jens Pohlmann, Susanne Rohrig, Elisabeth Perzborn, Karl-Heinz Schlemmer
  • Combination Therapy Comprising Substituted Oxazolidinones for the Prevention and Treatment of Cerebral Circulatory Disorders
    Publication number: 20080306070
    Abstract: The present invention relates to combinations of A) oxazolidinones of the formula (I), with B) antiarrhythmics, processes for the production of these combinations, their use for the prophylaxis and/or treatment of diseases, and their use for the manufacture of medicaments for the prophylaxis and/or treatment of diseases, especially of thromboembolic disorders and/or complications.
    Type: Application
    Filed: September 22, 2006
    Publication date: December 11, 2008
    Applicant: BAYER HEALTHCARE AG
    Inventors: Elisabeth Perzborn, Thomas Krahn
  • Cyclic Iminocarbamates And Their Use
    Publication number: 20080214533
    Abstract: The invention relates to novel cyclic iminocarbamates of formula (I), wherein R1, R2, R3, A, Z, and n have the meanings recited in the description, to a method for the production thereof, to pharmaceutical compositions containing such materials, and to methods for the treatment and/or prophylaxis of thromboembolic diseases using them.
    Type: Application
    Filed: November 22, 2005
    Publication date: September 4, 2008
    Applicant: BAYER HEALTHCARE AG
    Inventors: Susanne Rohrig, Jens Pohlmann, Sabine Arndt, Mario Jeske, Metin Akbaba, Elisabeth Perzborn, Christoph Gerdes, Karl-Heinz Schlemmer, Arounarith Tuch, Mario Lobell, Peter Nell, Nils Burkhardt
  • SUBSTITUTED OXAZOLIDINONES AND THEIR USE IN THE FIELD OF BLOOD COAGULATION
    Publication number: 20080200674
    Abstract: The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
    Type: Application
    Filed: February 7, 2008
    Publication date: August 21, 2008
    Applicant: Bayer Healthcare Aktiengesellschaft
    Inventors: Alexander Straub, Thomas Lampe, Jens Pohlmann, Susanne Rohrig, Elisabeth Perzborn, Karl-Heinz Schlemmer, Joseph Pernerstorfer
  • 2-Phenyl substituted imidazotriazinones as phosphodiesterase inhibitors
    Publication number: 20080113972
    Abstract: The 2-phenyl-substituted imidazotriazinones having short, unbranched alkyl radicals in the 9-position are prepared from the corresponding 2-phenyl-imidazotriazinones by chlorosulphonation and subsequent reaction with the amines. The compounds inhibit cGMP-metabolizing phosphodiesterases and are suitable for use as active compounds in pharmaceuticals, for the treatment of cardiovascular and cerebrovascular disorders and/or disorders of the urogenital system, in particular for the treatment of erectile dysfunction.
    Type: Application
    Filed: December 21, 2007
    Publication date: May 15, 2008
    Applicant: Bayer Aktiengesellschaft
    Inventors: Ulrich Niewohner, Mazen Es-Sayed, Helmut Haning, Thomas Schenke, Karl-Heinz Schlemmer, Jorg Keldenich, Erwin Bischoff, Elisabeth Perzborn, Klaus Dembowsky, Peter Serno, Marc Nowakowski, Maria Niewohner
  • SUBSTITUTED OXAZOLIDINONES AND THEIR USE IN THE FIELD OF BLOOD COAGULATION
    Publication number: 20080090815
    Abstract: The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
    Type: Application
    Filed: October 31, 2007
    Publication date: April 17, 2008
    Inventors: Alexander Straub, Thomas Lampe, Jens Pohlmann, Susanne Rohrig, Elisabeth Perzborn, Karl-Heinz Schlemmer, Joseph Pernerstorfer
  • Novel dicarboxylic acid derivatives with pharmaceutical properties
    Publication number: 20080058314
    Abstract: The present invention relates to the use of compounds of the formula (I) and to their salts and stereoisomers, for the preparation of medicaments for the treatment of cardiovascular disorders.
    Type: Application
    Filed: June 27, 2007
    Publication date: March 6, 2008
    Inventors: Cristina Alonso-Alija, Markus Heil, Dietmar Flubacher, Paul Naab, Johannes-Peter Stasch, Frank Wunder, Klaus Dembowsky, Elisabeth Perzborn, Elke Stahl
  • Substituted isoindoles and their use
    Publication number: 20080039446
    Abstract: The invention relates to coagulation of the blood. Disclosed are novel compounds of formula (I), a method for the production of these compounds, pharmaceutical compositions containing them, and methods of using them for the prevention and/or treatment of various diseases.
    Type: Application
    Filed: March 12, 2007
    Publication date: February 14, 2008
    Applicant: Bayer HealthCare AG
    Inventors: Alexander Straub, Thomas Lampe, Jens Pohlmann, Susanne Rohrig, Elisabeth Perzborn, Karl-Heinz Schlemmer
  • Methods of treating medical conditions using sulfonate-substituted pyrazolopyridine derivatives
    Patent number: 7317016
    Abstract: This invention relates to methods of treatment of cardiovascular disorders, thromboembolic disorders, inflammation, and disorders of the central nervous system using pyrazol pyridine derivatives of formula (I) wherein R1 is a radical of the formula —O—SO2—R3 in which R3 is optionally substituted C1-6-alkyl, optionally substituted C3-8-cycloalkyl, or optionally substituted phenyl; R2 is H, optionally substituted C1-6-alkyl-CO— or optionally substituted C1-6-alkyl-SO2—; as well as salts, stereoisomers, tautomers, and hydrates thereof.
    Type: Grant
    Filed: July 5, 2005
    Date of Patent: January 8, 2008
    Assignee: Bayer Aktiengesellschaft
    Inventors: Johannes-Peter Stasch, Achim Feurer, Stefan Weigand, Elke Stahl, Dietmar Flubacher, Cristina Alonso-Alija, Frank Wunder, Dieter Lang, Klaus Dembowsky, Alexander Straub, Elisabeth Perzborn
  • 2-phenyl substituted imidazotriazinones as phosphodiesterase inhibitors, for treatment of hypertension
    Patent number: 7314871
    Abstract: The application claims a method for treating hypertension by administering an effective amount of a compound of the formula (I) wherein the variable groups are as defined in the specification and claims. These 2-phenyl-substituted imidazotriazinones having short, unbranched alkyl radicals in the 9-position are prepared from the corresponding 2-phenyl-imidazotriazinones by chlorosulphonation and subsequent reaction with the amines. The compounds inhibit cGMP-metabolizing phosphodiesterases and are suitable for use as active compounds in pharmaceuticals, for the treatment of cardiovascular and cerebrovascular disorders and/or disorders of the urogenital system, in particular for the treatment of erectile dysfunction.
    Type: Grant
    Filed: April 21, 2006
    Date of Patent: January 1, 2008
    Assignee: Bayer Aktiengesellschaft
    Inventors: Maria Niewöhner, legal representative, Mazen Es-Sayed, Helmut Haning, Thomas Schenke, Karl-Heinz Schlemmer, Jörg Keldenich, Erwin Bischoff, Elisabeth Perzborn, Klaus Dembowsky, Peter Serno, Marc Nowakowski, Ulrich Niewöhner, deceased
  • Heterocyclic compounds
    Publication number: 20070066615
    Abstract: The present invention relates to the area of blood clotting. The invention relates in particular to certain heterocyclic compounds, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases.
    Type: Application
    Filed: May 6, 2004
    Publication date: March 22, 2007
    Applicant: BAYER HEATHCARE AG
    Inventors: Christoph Gerdes, Elisabeth Perzborn, Jens Pohlmann, Susanne Rohrig, Alexander Straub, Christian Thomas, Arounarith Tuch, Karl-Heinz Schlemmer
  • Substituted isoindoles and their use thereof
    Patent number: 7189738
    Abstract: The invention relates to coagulation of the blood. Disclosed are novel compounds of formula (I), a method for the production of these compounds, pharmaceutical compositions containing them, and methods of using them for the prevention and/or treatment of various diseases.
    Type: Grant
    Filed: July 17, 2002
    Date of Patent: March 13, 2007
    Assignee: Bayer Healthcare AG
    Inventors: Alexander Straub, Thomas Lampe, Jens Pohlmann, Susanne Rohrig, Elisabeth Perzborn, Karl-Heinz Schlemmer
  • Substituted oxazolidinones and their use in the field of blood coagulation
    Patent number: 7157456
    Abstract: The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
    Type: Grant
    Filed: December 11, 2000
    Date of Patent: January 2, 2007
    Assignee: Bayer HealthCare AG
    Inventors: Alexander Straub, Thomas Lampe, Jens Pohlmann, Susanne Röhrig, Elisabeth Perzborn, Karl-Heinz Schlemmer, Joseph Pernerstorfer
  • Pyrazinedicarboxamides and their use
    Publication number: 20060287315
    Abstract: The present invention relates to novel pyridinedicarboxamides, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular thromboembolic disorders.
    Type: Application
    Filed: December 8, 2005
    Publication date: December 21, 2006
    Applicant: Bayer HealthCare AG
    Inventors: Susanne Rohrig, Mario Jeske, Metin Akbaba, Ulrich Rosentreter, Stephen Boyer, Karin Fischer, Jens Pohlmann, Arounarith Tuch, Elisabeth Perzborn, Christoph Gerdes, Karl-Heinz Schlemmer, Nils Burkhardt, Swen Allerheiligen, Peter Nell, Sabine Arndt, Mario Lobell
  • Substituted 2-thio-3,5-dicyano-4-aryl-6-aminopyridines and their use
    Publication number: 20060264432
    Abstract: The invention relates to compounds of general formula (I), a method for the production thereof and the use thereof as pharmacologically effective substances for a broad medical indication spectrum. Furthermore, selective adenosine receptor ligands, preferably selective adenosine A1-, adenosine A2a- and/or adenosine A2b-receptor ligands are provided for the prophylaxis and/or the treatment of diseases, especially cardiovascular diseases, diseases of the urogenital region, diseases of the respiratory tract, inflammatory and neuroinflammatory diseases, diabetes, especially pancreatic diabetes, neurodegenerative diseases, pain states, cancer as well as liver fibrosis and liver cirrhosis.
    Type: Application
    Filed: February 21, 2006
    Publication date: November 23, 2006
    Inventors: Ulrich Rosentreter, Rolf Henning, Marcus Bauser, Thomas Kramer, Andrea Vaupel, Walter Hubsch, Klaus Dembowsky, Olga Salcher-Schraufstatter, Johannes-Peter Stasch, Thomas Krahn, Elisabeth Perzborn
  • Substituted Oxazolidinones and Their Use in the Field of Blood Coagulation
    Publication number: 20060258724
    Abstract: The invention relates to the field of blood coagulation. Novel oxazolidinone derivatives of the general formula (I) processes for their preparation and their use as medicinally active compounds for the prophylaxis and/or treatment of disorders are described.
    Type: Application
    Filed: July 27, 2006
    Publication date: November 16, 2006
    Inventors: Alexander Straub, Thomas Lampe, Jens Pohlmann, Susanne Rohrig, Elisabeth Perzborn, Karl-Heinz Schlemmer, Joseph Pernerstorfer
  • Substituted 2-thio-3,5-dicyano-4-aryl-6-aminopyridines and the use thereof
    Patent number: 7135486
    Abstract: This application relates to compounds of formula (I), wherein R1, R2, R3, and R4 are defined as recited in the claims, or a tautomer, salt, hydrate, or alkoxide thereof. A process for preparing such materials, pharmaceutical compositions containing them, and methods of treating a cardiovascular disorder by administering them to a patient are also disclosed and claimed.
    Type: Grant
    Filed: September 19, 2000
    Date of Patent: November 14, 2006
    Assignee: Bayer Aktiengeselischaft
    Inventors: Ulrich Rosentreter, Rolf Henning, Marcus Bauser, Thomas Krämer, Andrea Vaupel, Walter Hübsch, Klaus Dembowsky, Olga Salcher-Schraufstätter, Johannes-Peter Stasch, Thomas Krahn, Elisabeth Perzborn