Patents by Inventor Ellen Chi

Ellen Chi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human tissue factor antibody and uses thereof
    Patent number: 8999333
    Abstract: The invention relates to a humanized form of an antibody capable of preventing tissue factor (coagulation factor F3) signaling but which does not interfere with Factor VII binding or FX binding to tissue factor and does not prolong coagulation time. The antibody of the invention is useful in treating conditions, such as tumor progression, in which the associated cells express tissue factor and tissue factor signaling occurs.
    Type: Grant
    Filed: March 31, 2014
    Date of Patent: April 7, 2015
    Assignee: Janssen Biotech, Inc.
    Inventors: Juan Carlos Almagro, Glenn Mark Anderson, Ellen Chi, Christian Martinez, Gopalan Raghunathan, Ronald Swanson, Alexey Teplyakov, Kam-Fai Tse, Sheng-Jiun Wu, Hong Mimi Zhou
  • Human Autotaxin Antibodies and Methods of Use
    Publication number: 20150087812
    Abstract: Antibodies and compositions capable of binding and, in a particular aspect, inhibiting the lysophosphatidylipase D activity of human autotaxin protein. The antibodies or are useful in detecting human autotaxin protein and treating diseases and disorders associated with unwanted lysophosphatidylipase D and the presence of lysophosphatidic acid, such as cancer and pulmonary diseases.
    Type: Application
    Filed: March 11, 2013
    Publication date: March 26, 2015
    Applicant: JANSSEN BIOTECH, INC.
    Inventors: Ellen Chi, Thai Dinh, Suzanne Edavettal, Sandra Fenton, Damon Hamel, Sheri Moores, Jose Pardinas, H. Mimi Zhou, Barry L. Ziober
  • Human tissue factor antibody and uses thereof
    Patent number: 8951525
    Abstract: The invention relates to a humanized form of an antibody capable of preventing tissue factor (coagulation factor F3) signaling but which does not interfere with Factor VII binding or FX binding to tissue factor and does not prolong coagulation time. The antibody of the invention is useful in treating conditions, such as tumor progression, in which the associated cells express tissue factor and tissue factor signaling occurs.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: February 10, 2015
    Assignee: Janssen Biotech, Inc.
    Inventors: Juan Carlos Almagro, Glenn Mark Anderson, Ellen Chi, Christian Martinez, Gopalan Raghunathan, Ronald Swanson, Alexey Teplyakov, Kam-Fai Tse, Sheng-Jiun Wu, Hong Mimi Zhou
  • Nitrilases
    Patent number: 8906663
    Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: November 16, 2012
    Date of Patent: December 9, 2014
    Assignee: Verenium Corporation
    Inventors: David Weiner, Ellen Chi, Jennifer Ann Chaplin, Aileen Milan, Jay M. Short, Grace DeSantis, Mark Madden, Mark J. Burk, Dan E. Robertson
  • Interferon Alpha and Omega Antibody Antagonists
    Publication number: 20140271648
    Abstract: Broadly neutralizing interferon-? and interferon-? antibody antagonists, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing are useful in the treatment of diseases associated with increased production of IFN? and IFN?.
    Type: Application
    Filed: March 13, 2014
    Publication date: September 18, 2014
    Applicant: Janssen Biotech, Inc.
    Inventors: Ellen Chi, Judith Connor, Chichi Huang, Jarrat Jordan, Xiefan Lin-Schmidt, Jinquan Luo, Lu Lu, Christian Martinez, Galina Obmolova, Ronald Swanson
  • Kv1.3 Antagonists and Methods of Use
    Publication number: 20140255401
    Abstract: The present invention relates to Kv1.3 antagonists, and polynucleotides encoding them, and methods of making and using the foregoing.
    Type: Application
    Filed: January 24, 2014
    Publication date: September 11, 2014
    Applicant: Janssen Biotech, Inc.
    Inventors: Ellen Chi, Wilson Edwards, Chichi Huang, Wai-Ping Leung, Ronald Swanson, Alan Wickenden
  • HUMAN TISSUE FACTOR ANTIBODY AND USES THEREOF
    Publication number: 20140234304
    Abstract: The invention relates to a humanized form of an antibody capable of preventing tissue factor (coagulation factor F3) signaling but which does not interfere with Factor VII binding or FX binding to tissue factor and does not prolong coagulation time. The antibody of the invention is useful in treating conditions, such as tumor progression, in which the associated cells express tissue factor and tissue factor signaling occurs.
    Type: Application
    Filed: March 31, 2014
    Publication date: August 21, 2014
    Applicant: Janssen Biotech, Inc.
    Inventors: Juan Carlos ALMAGRO, Glenn Mark Anderson, Ellen Chi, Christian Martinez, Gopalan Raghunathan, Ronald Swanson, Alexey Teplyakov, Kam-Fai Tse, Sheng-Jiun Wu, Hong Mimi Zhou
  • Polynucleotides encoding engineered plant cysteine proteases and their uses
    Patent number: 8759067
    Abstract: The present invention relates to potato virus NIa protease variants or fragments thereof, polynucleotides encoding them, and methods of making and using the foregoing.
    Type: Grant
    Filed: March 22, 2013
    Date of Patent: June 24, 2014
    Assignee: Centocor Ortho Biotech Inc.
    Inventors: Ellen Chi, Michael Hunter, Ronald Swanson
  • Human tissue factor antibody and uses thereof
    Patent number: 8722044
    Abstract: The invention relates to a humanized form of an antibody capable of preventing tissue factor (coagulation factor F3) signaling but which does not interfere with Factor VII binding or FX binding to tissue factor and does not prolong coagulation time. The antibody of the invention is useful in treating conditions, such as tumor progression, in which the associated cells express tissue factor and tissue factor signaling occurs.
    Type: Grant
    Filed: February 17, 2012
    Date of Patent: May 13, 2014
    Assignee: Janssen Biotech, Inc.
    Inventors: Juan Carlos Almagro, Glenn Mark Anderson, Ellen Chi, Christian Martinez, Gopalan Raghunathan, Ronald Swanson, Alexey Teplyakov, Kam-Fai Tse, Sheng-Jiun Wu, Hong Mimi Zhou
  • Engineered plant cysteine proteases and their uses
    Publication number: 20130196413
    Abstract: The present invention relates to potato virus NIa protease variants or fragments thereof, polynucleotides encoding them, and methods of making and using the foregoing.
    Type: Application
    Filed: March 22, 2013
    Publication date: August 1, 2013
    Applicant: CENTOCOR ORTHO BIOTECH INC.
    Inventors: Ellen Chi, Michael Hunter, Ronald Swanson
  • Human Tissue Factor Antibody and Uses Thereof
    Publication number: 20130189250
    Abstract: The invention relates to a humanized form of an antibody capable of preventing tissue factor (coagulation factor F3) signaling but which does not interfere with Factor VII binding or FX binding to tissue factor and does not prolong coagulation time. The antibody of the invention is useful in treating conditions, such as tumor progression, in which the associated cells express tissue factor and tissue factor signaling occurs.
    Type: Application
    Filed: March 14, 2013
    Publication date: July 25, 2013
    Applicant: JANSSEN BIOTECH, INC.
    Inventors: Juan Carlos Almagro, Glenn Mark Anderson, Ellen Chi, Christian Martinez, Gopalan Raghunathan, Ronald Swanson, Alexey Teplyakov, Kam-Fai Tse, Sheng-Jiun Wu, Hong Mimi Zhou
  • Engineered potato virus A nuclear inclusion protein
    Patent number: 8426186
    Abstract: The present invention relates to potato virus NIa protease variants or fragments thereof, polynucleotides encoding them, and methods of making and using the foregoing.
    Type: Grant
    Filed: April 14, 2011
    Date of Patent: April 23, 2013
    Assignee: Centocor Ortho Biotech Inc.
    Inventors: Ellen Chi, Michael Hunter, Ronald Swanson
  • Engineered anti-IL-13 antibodies, compositions, methods and uses
    Patent number: 8399630
    Abstract: The present invention relates to engineered antibodies immuno specific for human interleukin-13 (IL-13) protein or fragment thereof, as well as methods of making and using thereof, including therapeutic indications.
    Type: Grant
    Filed: August 11, 2009
    Date of Patent: March 19, 2013
    Assignee: Centocor Ortho Biotech Inc.
    Inventors: Ronald V. Swanson, Ellen Chi, Gopalan Raghunathan, Shanrong Zhao, Johan Fransson, Wendy Cordier, Hong Mimi Zhou, Juan C. Almagro, Linus Hyun, Jill Giles-Komar, Karyn T. O'Neil, Jill M. Carton, Alexey V. Teplyakov, Yiqing Feng
  • Nucleic acids encoding nitrilases
    Patent number: 8334125
    Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: June 27, 2011
    Date of Patent: December 18, 2012
    Assignee: Verenium Corporation
    Inventors: Grace DeSantis, Ellen Chi, Jennifer Ann Chaplin, Aileen Milan, Jay Short, David Weiner, Mark Madden, Darcy Madden, legal representative, Mark Burk, Dan Robertson
  • Engineered anti-IL-13 antibodies, compositions, methods and uses
    Patent number: 8323646
    Abstract: The present invention relates to engineered antibodies immunospecific for human interleukin-13 (IL-13) protein or fragment thereof, as well as methods of making and using thereof, including therapeutic indications.
    Type: Grant
    Filed: August 12, 2009
    Date of Patent: December 4, 2012
    Assignee: Centocor Ortho Biotech Inc.
    Inventors: Ronald V. Swanson, Ellen Chi, Gopalan Raghunathan, Shanrong Zhao, Johan Fransson, Wendy Cordier, Hong Mimi Zhou, Juan C. Almagro, Linus Hyun, Jill Giles-Komar, Karyn T. O'Neil, Jill M. Carton, Alexey V. Teplyakov, Yiging Feng
  • Human Tissue Factor Antibody and Uses Thereof
    Publication number: 20120237528
    Abstract: The invention relates to a humanized form of an antibody capable of preventing tissue factor (coagulation factor F3) signaling but which does not interfere with Factor VII binding or FX binding to tissue factor and does not prolong coagulation time. The antibody of the invention is useful in treating conditions, such as tumor progression, in which the associated cells express tissue factor and tissue factor signaling occurs.
    Type: Application
    Filed: February 17, 2012
    Publication date: September 20, 2012
    Inventors: Juan Carlos Almagro, Glenn Mark Anderson, Ellen Chi, Christian Martinez, Gopalan Raghunathan, Ronald Swanson, Alexey Teplyakov, Kam-Fai Tse, Sheng-Jiun Wu, Hong Mimi Zhou
  • ENGINEERED ANTI-IL-13 ANTIBODIES, COMPOSITIONS, METHODS AND USES
    Publication number: 20120045438
    Abstract: The present invention relates to engineered antibodies immuno specific for human interleukin-13 (IL-13) protein or fragment thereof, as well as methods of making and using thereof, including therapeutic indications.
    Type: Application
    Filed: August 11, 2009
    Publication date: February 23, 2012
    Inventors: Ronald V. Swanson, Ellen Chi, Gopalan Raghunathan, Shanrong Zhao, Johan Fransson, Wendy Cordier, Hong Mimi Zhou, Juan C. Almagro, Linus Hyun, Jill Giles-Komar, Karyn T. O'Neil, Jill M. Carton, Alexey V. Teplyakov, Yiqing Feng
  • Engineered Plant Cysteine Proteases and Their Uses
    Publication number: 20110318808
    Abstract: The present invention relates to potato virus NIa protease variants or fragments thereof, polynucleotides encoding them, and methods of making and using the foregoing.
    Type: Application
    Filed: April 14, 2011
    Publication date: December 29, 2011
    Inventors: Ellen Chi, Michael Hunter, Ronald Swanson
  • Nucleic Acids Encoding Nitrilases
    Publication number: 20110263839
    Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
    Type: Application
    Filed: June 27, 2011
    Publication date: October 27, 2011
    Applicant: VERENIUM CORPORATION
    Inventors: Grace DESANTIS, Jennifer Ann CHAPLIN, Ellen CHI, Aileen MILAN, Jay M. SHORT, David WEINER, Mark MADDEN, Darcy MADDEN, Mark J. BURK, Dan E. ROBERTSON
  • Nitrilases and methods for making and using them
    Patent number: 7993901
    Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: December 2, 2009
    Date of Patent: August 9, 2011
    Assignee: Verenium Corporation
    Inventors: Grace Desantis, Ellen Chi, Jennifer Ann Chaplin, Aileen Milan, Jay Short, David Weiner, Mark Madden, Marcy Madden, legal representative, Mark Burk, Dan Robertson