Patents by Inventor Ellen Chi

Ellen Chi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Differentiation of Pluripotent Stem Cells
    Publication number: 20110091971
    Abstract: The present invention is directed to methods to differentiate pluripotent stem cells. In particular, the present invention is directed to methods and compositions to differentiate pluripotent stem cells into cells expressing markers characteristic of the definitive endoderm lineage. The present invention also provides methods to generate and purify agents capable of differentiating pluripotent stem cells into cells expressing markers characteristic of the definitive endoderm lineage.
    Type: Application
    Filed: June 29, 2009
    Publication date: April 21, 2011
    Inventors: Janet Davis, Jiajian Liu, Gopalan Raghunathan, Michael Joseph Hunter, Jose Pardinas, Judith Ann Connor, Ronald Vernon Swanson, Ellen Chi
  • Nitrilases, Nucleic Acids Encoding Them and Methods for Making and Using Them
    Publication number: 20100273659
    Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
    Type: Application
    Filed: February 29, 2008
    Publication date: October 28, 2010
    Applicant: VERENIUM CORPORATION
    Inventors: Grace DeSantis, Jennifer Chaplin, Ellen Chi, Aileen Milan, Jay Short, David Weiner, Mark Madden, Darcy Madden, Dan Robertson
  • ENGINEERED ANTI-IL-13 ANTIBODIES, COMPOSITIONS, METHODS AND USES
    Publication number: 20100111959
    Abstract: The present invention relates to engineered antibodies immunospecific for human interleukin-13 (IL-13) protein or fragment thereof, as well as methods of making and using thereof, including therapeutic indications.
    Type: Application
    Filed: August 12, 2009
    Publication date: May 6, 2010
    Inventors: Ronald V. Swanson, Ellen Chi, Gopalan Raghunathan, Shanrong Zhao, Johan Fransson, Wendy Cordier, Hong Mimi Zhou, Juan C. Almagro, Linus Hyun, Jill Giles-Komar, Karyn T. O'Neil, Jill M. Carton, Alexey V. Teplyakov
  • Nitrilases and Methods for Making and Using Them
    Publication number: 20100086986
    Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
    Type: Application
    Filed: December 2, 2009
    Publication date: April 8, 2010
    Applicant: VERENIUM CORPORATION
    Inventors: Grace DESANTIS, Jennifer Ann CHAPLIN, Ellen CHI, Aileen MILAN, Jay M. SHORT, David WEINER, Mark MADDEN, Darcy MADDEN, Mark J. BURK, Dan E. ROBERTSON
  • Nitrilases
    Patent number: 7651849
    Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: March 3, 2009
    Date of Patent: January 26, 2010
    Inventors: Grace DeSantis, Ellen Chi, Jennifer Ann Chaplin, Aileen Milan, Jay M. Short, David Paul Weiner, Mark Madden, Darcy Madden, legal representative, Mark J. Burk, Dan E. Robertson
  • NITRILASES
    Publication number: 20090176976
    Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
    Type: Application
    Filed: March 3, 2009
    Publication date: July 9, 2009
    Inventors: Grace DESANTIS, Jennifer Ann Chaplin, Ellen Chi, Aileen Milan, Jay M. Short, David Weiner, Mark Madden, Mark J. Burk, Dan E. Robertson, Darcy Madden
  • Nitrilases and methods for making and using them
    Patent number: 7521216
    Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
    Type: Grant
    Filed: May 15, 2002
    Date of Patent: April 21, 2009
    Assignee: Verenium Corporation
    Inventors: Grace DeSantis, Jennifer Ann Chaplin, Ellen Chi, Aileen Milan, Jay M. Short, David Weiner, Darcy Madden, legal representative, Mark J. Burk, Dan E. Robertson, Mark Madden
  • Crystallization of 11-Beta-Hydroxysteroid Dehydrogenase type 1
    Patent number: 7241604
    Abstract: Provided are crystals relating to 11-Beta-Hydroxysteroid Dehydrogenase type 1 and its various uses.
    Type: Grant
    Filed: March 12, 2004
    Date of Patent: July 10, 2007
    Assignee: Takeda San Diego, Inc.
    Inventors: Kathleen Aertgeerts, Oleg Brodsky, Ellen Chi, Mark T. Hilgers, David J. Hosfield, Robert J. Skene
  • Assays and kits for detecting the presence of nitriles and/or cyanide
    Publication number: 20040038419
    Abstract: In one aspect, invention relates to the field of monitoring chemical reactions and, in one aspect, provides methods and kits for detecting the presence of nitrites and/or cyanide. In one aspect, the invention provides methods and kits for assaying catalytic activity of a material, such as an enzyme, in a chemical or biochemical process, or assaying catalytic activity of a material in a biological sample, such as a whole cell.
    Type: Application
    Filed: May 15, 2003
    Publication date: February 26, 2004
    Applicant: Diversa Corporation
    Inventors: David Paul Weiner, Jennifer Ann Chaplin, Ellen Chi, Aileen Milan, Grace DeSantis, Mark J. Burk, Jeffrey McQuaid, Justin Stege
  • Nitrilases
    Publication number: 20040002147
    Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
    Type: Application
    Filed: September 9, 2002
    Publication date: January 1, 2004
    Inventors: Grace Desantis, Jennifer Ann Chaplin, Ellen Chi, Aileen Milan, Jay M. Short, David Weiner, Mark J. Burk, Eric J. Mathur, Darcy Madden (Heir)
  • Nitrilases
    Publication number: 20030124698
    Abstract: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.
    Type: Application
    Filed: May 15, 2002
    Publication date: July 3, 2003
    Applicant: DIVERSA Corporation
    Inventors: Grace DeSantis, Jennifer Ann Chaplin, Ellen Chi, Aileen Milan, Jay M. Short, David Weiner, Mark Maddes, Darcy Madden, Mark J. Burk, Eric Mathur