Abstract: Embodiments of negative pressure wound therapy systems and methods for operating the systems are disclosed. In some embodiments, a system includes a negative pressure source, a wound dressing configured to be positioned over a wound, and optionally a canister configured to store fluid aspirated from the wound. The negative pressure source, wound dressing, and canister (when present) can be fluidically connected to facilitate delivery of negative pressure to the wound. The system can be configured to automatically detect whether the canister is positioned in the fluid flow path between the negative pressure source and the dressing while negative pressure source provides negative pressure to the wound dressing. Operation of the system can be adjusted based on whether presence of the canister has been detected. For example, a value of an operational parameter can be set to indicate that the canister is present.

Abstract: An ultrasonic probe assembly includes an ultrasonic probe having a housing, an ultrasonic sensor, at least one magnet, and rotatable joint portions. The housing extends along a longitudinal axis between first and second ends and includes a base surface. The sensor is secured adjacent a housing base surface configured to emit ultrasonic signals and receive ultrasonic echoes reflected from a target. The magnet is secured within the housing and configured to apply a magnetic force urging the base surface into contact with a surface of the target. The magnetic force frictionally maintains the housing at a stationary position with respect to the target surface. A first rotatable joint portion is positioned on a first lateral side of the housing. A second rotatable joint portion is positioned on a second lateral side of the housing, opposite the first lateral side.

Abstract: A dual polar ionization system that introduces ions into passenger transports for the purpose of air and surface purification. The system includes a dual polar ionization generator. The dual polar ionization generator including a control system, a communication system, a positive ion antenna, a negative ion antenna, and a power source. The communication system transmits dual polar ionization output parameters. The system also includes a dual polar ionization user interface for displaying functionality of the dual polar ionization generator including displaying a calculated ion output of the dual polar ionization generator.

Abstract: In some examples, just-in-time (JIT) control instructions upon execution cause a system to initiate a plurality of instances of JIT compilation of a first code called by a program, where the initiating of the plurality of instances of the JIT compilation of the first code is under control of the JIT control instructions that are outside the program, and the plurality of instances of the JIT compilation of the first code use respective different compilation settings, and are to produce respective JIT compiled instances of the first code.

Abstract: A system, method, and computer readable and executable media for detecting, alerting, managing, and optionally mitigating cyber security events on an aircraft's networks using an on-board cyber security appliance and applications that monitors and detects cyber security events in real time. A software selectable cyber security agent within the cyber security appliance mitigates (if enabled) the effects of a cyber security events and/or anomalies on the aircrafts networks while the aircraft is in-flight and/or on the ground.

Abstract: The present invention relates to systems and methods that utilize a combination of immunoassay and magnetic immunoassay techniques to detect an analyte within an extended range of specified concentrations. In particular, a device includes a housing, a heterogeneous surface capture immunosensor within the housing and configured to generate a first signal indicative of the concentration of the analyte in an upper concentration range, and a homogeneous magnetic bead capture immunosensor within the housing and configured to generate a second signal indicative of the concentration of the analyte in a lower concentration range.

Abstract: Described herein are systems and methods for neural machine translation (NMT) of languages between network operation systems. The languages may be a query language, such as a XML path, to navigate through elements and attributes in an XML document. An NMT model comprises an encoder and a decoder to implement the machine translation. The encoder encodes a source sentence as a sequence of encoder hidden states. The decoder may incorporate attention mechanism to generate a target sentence, conditioned on the encoder hidden states. The NMT model may also use a modified beam search with variable beam width and search scope for each search step to speed up search process with a balance of accuracy and processing cost. Evaluation results demonstrate that embodiments of the present disclosure may be used in a recommender system for XPath auto-generation between different network operation systems.

Abstract: A system, method and computer readable and executable media for detecting, alerting, managing and optionally mitigating cyber security events on an aircraft's networks using an on-board cyber security appliance and applications that monitors and detects cyber security events in real time. A software selectable cyber security agent within the cyber security appliance mitigates (if enabled) the effects of a cyber security events and/or anomalies on the aircrafts networks while the aircraft is in-flight and/or on the ground.

Abstract: In accordance with a version, one or more identification clips, identification clip systems, and methods are provided which safely attach to and identify a plurality of damaged shingles to visually demonstrate and ascertain the extent of roof damage from a distance, particularly from the perspective of someone standing on the ground.

Abstract: The present invention relates to systems and methods that utilize a combination of immunoassay and magnetic immunoassay techniques to detect an analyte within an extended range of specified concentrations. In particular, a device includes a housing, a heterogeneous surface capture immunosensor within the housing and configured to generate a first signal indicative of the concentration of the analyte in an upper concentration range, and a homogeneous magnetic bead capture immunosensor within the housing and configured to generate a second signal indicative of the concentration of the analyte in a lower concentration range.

Abstract: A system, method and computer readable and executable media for detecting, alerting, managing and optionally mitigating cyber security events on an aircraft's networks using an on-board cyber security appliance and applications that monitors and detects cyber security events in real time. A software selectable cyber security agent within the cyber security appliance mitigates (if enabled) the effects of a cyber security events and/or anomalies on the aircrafts networks while the aircraft is in-flight and/or on the ground.

Abstract: A method, according to some implementations, includes generating a plurality of base datasets using a random number generator and determining scenario specifications. The method may further include identifying at least one transformation function for at least one of the plurality of base datasets based on the scenario specifications and transforming the at least one of the plurality of base datasets using the at least one transformation function. In some cases, the method may also include generating scenario parameters based on the at least one transformed datasets.

Abstract: A method for trial design with pareto techniques is provided. The method includes obtaining trial design simulation results for a set of trial designs and determining a score for each trial design based on a performance criteria. The method further includes evaluating Pareto optimality for each design in the set of trial designs to determine a Pareto frontier, filtering designs that are not on the Pareto frontier, and communicating the Pareto frontier designs.

Abstract: A method for determining trial designs is provided. The method includes receiving, via at least one processor, one or more trial design criteria and one or more scenarios corresponding to a set of trial designs, and generating, via the at least one processor, simulation data based at least in part on replicating each of the set of trial designs with the one or more trial design criteria and the one or more scenarios. The simulation data includes performance parameters and performance parameter values associated with each design in the set of designs for a set of criteria. The method further includes determining, via the at least one processor, an optimality criteria for evaluating the trial designs, searching, within the set of trial designs, via the at least one processor, for globally optimum designs based on the optimality criteria, and transmitting, via the at least one processor, globally optimum designs.

Abstract: A method, according to some implementations, includes obtaining a criteria for a trial design study, determining permutations for designs in response to the criteria, and determining permutations for scenarios in response to the criteria. The method may further include generating combinations of the permutations for the designs and the permutations for the scenarios, simulating designs corresponding to the generated combinations, and determining performance of the simulated designs.

Abstract: A method for trial design includes presenting on a graphical interface, a set of cards, wherein each card in the set is representative of a different trial design from a set of trial designs. The method further includes: monitoring a first set of user interactions with the set of cards; determining a user preference for one or more values of one or more parameters of the set of trial designs from the first set of user interactions; and presenting on the graphical interface a new card that is representative of a trial design consistent with the determined user preference. The method may also include monitoring a second set of user interactions with the new card and refining the determined user preference based at least in part on the second set of user interactions with the new card.

Abstract: A method, according to some implementations, determining, via at least one processor, a plurality of possible sites for recruiting patients from for a trial and determining, via the at least one processor and for each of one or more subgroupings of the plurality of possible sites, a predicted available resources value. The method may further include determining, via the at least one processor, which subgrouping of the plurality of possible sites has a predicted available resources value that globally optimizes a desired site resource criteria.

Abstract: A method, according to some implementations, includes obtaining trial design simulation results for a set of trial designs and determining a set of Pareto designs in the set of trial designs based at least in part on the trial design simulation results and one or more performance parameters. The method further includes determining a set of convex hull designs in the set of trial designs, determining a set of recommended designs based at least in part on the set of Pareto designs and the set of convex hull designs, and transmitting the set of recommended designs.

Abstract: A method for determining trial designs is provided. The method includes obtaining simulation data for a set of trial designs. The simulation data includes performance parameters and performance parameter values associated with each design in the set of designs for a set of criteria; determining an optimality criteria for evaluating the trial designs; searching, within the set of trial designs, for globally optimum designs based on the optimality criteria; and recommending globally optimum designs.