Abstract: Check valve are disclosed having a primary seal and a secondary seal, where the primary and secondary seals resist movement of a fluid through the check valve, and the secondary seal can provide a backup seal in an instance where the check valve does not function as intended. The primary and secondary seals can be formed by first and second sealing ridges, respectively, and a valve body can be positioned within the check valve, between a valve support, the first sealing ridge, and a second sealing ridge. The valve body is configured to move relative to the first and second sealing ridges, and can have a position wherein a portion of the valve body is engaged against any of the first and second sealing ridges.

Abstract: A check valve includes an upper housing defining an inlet of the check valve, a lower housing defining an outlet of the check valve, and a cavity interposed between and defined by the upper and lower housings for fluidly connecting the inlet and the outlet. The check valve further includes a valve member mounted in the cavity to selectively permit fluid flow in a first direction, and prevent fluid backflow in a second direction opposite to the first direction. The valve member includes a valve body and a valve stem portion extending axially through a central axis of the valve body. The valve member may further include a plurality of feet disposed about and extending longitudinally from an outer circumferential perimeter of the valve body.

Abstract: An physiological measurement device provides a device body having a base, legs extending from the base and an optical housing disposed at ends of the legs opposite the base. An optical assembly is disposed in the housing. The device body is flexed so as to position the housing over a tissue site. The device body is unflexed so as to attach the housing to the tissue site and position the optical assembly to illuminate the tissue site. The optical assembly is configured to transmit optical radiation into tissue site tissue and receive the optical radiation after attenuation by pulsatile blood flow within the tissue.

Abstract: Check valve assemblies for fluid flow sets and devices are provided. The check valve assembly includes an inlet body including a fluid inlet, a first seal bead and a second seal bead, and an outlet body including a fluid outlet. A seal includes inner and outer rings, wherein, in a fully sealed position of the check valve assembly, the inner ring is configured to engage with the first seal bead and the outer ring is configured to engage with the second seal bead. Fluid flow sets and methods for manufacturing check valve assemblies are also provided.

Abstract: A check valve includes an upper housing defining an inlet of the check valve, a lower housing defining an outlet of the check valve, and a cavity interposed between and defined by the upper and lower housings for fluidly connecting the inlet and the outlet. The check valve further includes a valve member mounted in the cavity to selectively permit fluid flow in a first direction, and prevent fluid backflow in a second direction opposite to the first direction. The valve member includes a valve body and a valve stem portion extending axially through a central axis of the valve body. The valve member may further include a plurality of feet disposed about and extending longitudinally from an outer circumferential perimeter of the valve body.

Abstract: A method of manufacturing a check valve may include forming an upper housing as cylindrical body with (i) an internal surface including an upstream internal surface and a downstream internal surface having a projection and (ii) an external surface, forming a T-shaped filter member and mounting the T-shaped filter member in the internal surface of the upper housing. The method may further include forming a lower housing with a support portion at a central portion thereof, mounting a flexible valve member on the support portion, and coupling the upper housing with T-shaped filter member mounted therein onto the lower housing with flexible valve member mounted therein such that the T-shaped filter member is disposed upstream of the flexible valve member.

Abstract: A check valve includes a housing that includes an inlet port, an outlet port, and a valve chamber. The inlet port extends from a ceiling of the valve chamber to an outer surface of the housing. The outlet port extends from a floor of the valve chamber to the outer surface of the housing. The check valve further includes a valve member supported within the chamber. The valve includes a valve head. When an upstream pressure is applied to the valve, the valve head is configured to deflect away from the ceiling of the valve chamber and unseal the inlet port. When a downstream pressure is applied to the valve, the valve head is configured to deflect away from the floor of the valve chamber and seal the inlet port such that the valve head conforms to a shape of the ceiling of the valve chamber.

Abstract: Syringes are described herein. A syringe includes a syringe body, a first plunger, a biasing member, and a retention member. The syringe body defines a syringe cavity and a syringe port, wherein the syringe port is in fluid communication with the syringe cavity. The first plunger comprises a first plunger shaft extending from the first plunger, the first plunger disposed within the syringe cavity and defining a first chamber in the syringe cavity, wherein the first chamber is in fluid communication with the syringe port. The biasing member is coupled to the first plunger shaft, wherein the biasing member urges the first plunger to advance toward the syringe port. The retention mechanism prevents the biasing member from advancing the first plunger in an engaged position and permits the biasing member to advance the first plunger in a released position.

Abstract: IV filters are described herein. An IV filter includes a body, a filter media, and a bulb. The body defines a body volume. The filter media is disposed within the body volume. The filter media defines an inlet portion of the body volume and an outlet portion of the body volume. The filter media permits inlet flow from the inlet portion of the body volume to the outlet portion of the body volume and captures particulate from the inlet flow. The bulb defines a bulb volume in fluid communication with the outlet portion of the body volume. The bulb is deformable to compress the bulb volume and direct back flow from the outlet portion of the body volume through the filter media and into the inlet portion of the body volume, displacing particulate captured in the filter media into the inlet portion of the body volume.

Abstract: A check valve includes a housing that includes an inlet port, an outlet port, and a valve chamber. The inlet port extends from a ceiling of the valve chamber to an outer surface of the housing. The outlet port extends from a floor of the valve chamber to the outer surface of the housing. The check valve further includes a valve member supported within the chamber. The valve includes a valve head. When an upstream pressure is applied to the valve, the valve head is configured to deflect away from the ceiling of the valve chamber and unseal the inlet port. When a downstream pressure is applied to the valve, the valve head is configured to deflect away from the floor of the valve chamber and seal the inlet port such that the valve head conforms to a shape of the ceiling of the valve chamber.

Abstract: Check valve assemblies for fluid flow sets and devices are provided. The check valve assembly includes an inlet body including a fluid inlet, a first seal bead and a second seal bead, and an outlet body including a fluid outlet. A seal includes inner and outer rings, wherein, in a fully sealed position of the check valve assembly, the inner ring is configured to engage with the first seal bead and the outer ring is configured to engage with the second seal bead. Fluid flow sets and methods for manufacturing check valve assemblies are also provided.

Abstract: Syringes are described herein. A syringe includes a syringe body, a first plunger, a biasing member, and a retention member. The syringe body defines a syringe cavity and a syringe port, wherein the syringe port is in fluid communication with the syringe cavity. The first plunger comprises a first plunger shaft extending from the first plunger, the first plunger disposed within the syringe cavity and defining a first chamber in the syringe cavity, wherein the first chamber is in fluid communication with the syringe port. The biasing member is coupled to the first plunger shaft, wherein the biasing member urges the first plunger to advance toward the syringe port. The retention mechanism prevents the biasing member from advancing the first plunger in an engaged position and permits the biasing member to advance the first plunger in a released position.

Abstract: Various aspects of the subject disclosure relate to a compounder system having a cartridge that includes fluid pathways controllable by valves of the cartridge. A pump component within the cartridge is actuable to move fluid through the controllable fluid pathways. The cartridge includes a backpack for management of tubing to couple the cartridge to a receiving container. A disposable waste container is contained by the cartridge and the backpack. A syringe holder is provided for use of a syringe as a receiving container to receive a compounded medication.

Abstract: Check valve assemblies for fluid flow sets and devices are provided. The check valve assembly includes an inlet body including a fluid inlet, first and second seal beads, and a central channel. An outlet body includes a fluid outlet and a stem having a centering post, the centering post received by the central channel of the inlet body. A seal includes inner and outer rings, wherein the inner ring is configured to engage with the first seal bead and the outer ring is configured to engage with the second seal bead in a fully sealed position of the check valve assembly. Fluid flow sets and methods for manufacturing check valve assemblies are also provided.

Abstract: Syringe assemblies are described herein. A syringe assembly includes an assembly housing, a first syringe, a second syringe, and a connecting gear. The first syringe is disposed within the assembly housing. Each plunger is movable within the respective syringe cavity and defines a respective chamber in the respective syringe cavity, wherein the respective chamber is in fluid communication with the respective syringe port, the respective plunger comprising a respective gear rack extending longitudinally along the respective plunger. The connecting gear is rotatably coupled to the assembly housing. The connecting gear is configured to be in meshed engagement with at least one of the first gear rack and the second gear rack of the syringes.

Abstract: Syringes are described herein. A syringe includes a syringe body, a first plunger, a second plunger, and an inner tube. The syringe body defines a syringe cavity and a syringe port, wherein the syringe port is in fluid communication with the syringe cavity. The first plunger is disposed within the syringe cavity and defining a first chamber in the syringe cavity, wherein the first chamber is in fluid communication with the syringe port. The second plunger is disposed within the syringe cavity, the first plunger and the second plunger cooperatively defining a second chamber in the syringe cavity. The inner tube comprises an inner tube lumen, wherein the inner tube and the first plunger shaft lumen define an annulus therebetween, the annulus in fluid communication with the first plunger channel and the annulus permits fluid communication between the syringe port and the first plunger channel.

Abstract: A method of manufacturing a check valve may include forming an upper housing as cylindrical body with (i) an internal surface including an upstream internal surface and a downstream internal surface having a projection and (ii) an external surface, forming a T-shaped filter member and mounting the T-shaped filter member in the internal surface of the upper housing. The method may further include forming a lower housing with a support portion at a central portion thereof, mounting a flexible valve member on the support portion, and coupling the upper housing with T-shaped filter member mounted therein onto the lower housing with flexible valve member mounted therein such that the T-shaped filter member is disposed upstream of the flexible valve member.

Abstract: Syringe assemblies are described herein. A syringe assembly includes an assembly housing, a first syringe, a second syringe, and a connecting gear. The first syringe is disposed within the assembly housing. Each plunger is movable within the respective syringe cavity and defines a respective chamber in the respective syringe cavity, wherein the respective chamber is in fluid communication with the respective syringe port, the respective plunger comprising a respective gear rack extending longitudinally along the respective plunger. The connecting gear is rotatably coupled to the assembly housing. The connecting gear is configured to be in meshed engagement with at least one of the first gear rack and the second gear rack of the syringes.

Abstract: A syringe includes a syringe body, a first plunger, a second plunger, and an inner tube. The syringe body defines a syringe port in fluid communication with a syringe cavity. The first plunger is disposed within the syringe cavity and defines a first chamber in the syringe cavity, wherein the first chamber is in fluid communication with the syringe port. The second plunger is disposed within the syringe cavity, the first plunger and the second plunger cooperatively defining a second chamber in the syringe cavity. The inner tube comprises an inner tube lumen, wherein the inner tube and a first plunger shaft lumen of a first plunger shaft define an annulus therebetween, the annulus in fluid communication with a first plunger channel of the first plunger and the annulus permits fluid communication between the syringe port and the first plunger channel.

Abstract: A dual-chamber syringe may include an end wall and a primary plunger. The primary plunger may include a primary stopper. The primary stopper may form a primary chamber with the end wall. A secondary plunger may be in mechanical association with the primary plunger. The secondary plunger may include a secondary stopper. The secondary stopper may form a secondary chamber with the primary stopper. A primary nozzle may extend from the end wall and may be in fluid communication with the primary chamber. A secondary nozzle may extend from the end wall and may be in fluid communication with the secondary chamber.