Abstract: A cell chip includes first, second and third elements, a dye dialysis layer, a micro-channel structure and washing solution inlet and outlet. The first element has a first hole and second holes at opposite sides of the first hole. The second element has a third hole corresponding to the first hole and fourth holes corresponding to the second holes. The dye dialysis layer is inserted between the first element and the second element and has a cell-assembly region corresponding to the first and third holes. The micro-channel structure is disposed below the cell-assembly region and between the second and the third elements. The washing solution inlet and outlet are communicatively connected to the micro-channel structure. The washing solution inlet includes the second hole and a corresponding fourth hole. A washing solution flows in the micro-channel structure through the washing solution inlet and outlet.

Abstract: A conveying pipeline including a bionic tube, a delivery tube, and a shrinkable tube is provided. A portion of the delivery tube is located in the bionic tube, so that the bionic tube has an overlapping region with the delivery tube. The shrinkable tube wraps the bionic tube located in the overlapping region.

Abstract: An integrated chip is provided and comprises systems for sperm sorting, oocyte incubation and fertilization and liquid perfusion. The sperm sorting system comprises an inlet, an outlet, a main channel and a branch channel. The main channel has a width which increases along a direction from the inlet toward the outlet. The branch channel is connected to the main channel. The oocyte incubation and fertilization system is connected to the branch channel and comprises upper and lower holes. The upper hole is larger than the oocyte to hold the oocyte to be fertilized by a sperm. The lower hole is smaller than the oocyte. The sorted sperms are introduced into the oocyte incubation and fertilization system through the branch channel, to fertilize with the oocytes in the upper holes. The liquid perfusion system is located below the lower holes and a liquid exchange is performed through the second holes.

Abstract: A metal ion detection equipment and a metal ion detection method are provided. The metal ion detection equipment includes a porous silicon resonant cavity structure, an electrochemical device and a spectrum detecting device. A sample solution permeates into the porous silicon resonant cavity structure. A to-be-detected metal ion of the sample solution in the porous silicon resonant cavity structure is reduced into a to-be-detected metal by the electrochemical device. The spectrum detecting device detects a spectral variation of a reflective light from the porous silicon resonant cavity structure.

Abstract: This invention relates to microfluidic chips for and their applications in acquiring sperms with high velocity and/or motility. The microfluidic chip comprises an inlet region, a first flow channel, a divergent channel, an optional block structure with rounded corners and one or more outlet region(s). The invention mimics sperm activation process in body and designs a microfluidic chip mimicking the activation process so that higher amount of populations and/or subpopulations of sperms with high motility can be acquired.

Abstract: A manufacturing method of a proton exchange membrane is provided, which includes the steps as follows. The hydroxyl groups are disposed on the surface of a substrate by a hydrophilic treatment. The hydroxyl groups on the substrate are chemically modified with a coupling agent by a sol-gel process. The substrate is exposed to an amino acid with a phosphonate radical so that the amino acid containing a phosphonate radical can be chemically bonded with the coupling agent. The chemically bonded substrate is immersed in phosphoric acid for absorbing the phosphoric acid. The substrate blended with the phosphoric acid is placed between at least two leak-proof films for the purpose of preventing the leakage of the absorbed phosphoric acid. The proton exchange membrane manufactured by this method enable to retain the phosphoric acid in organic/inorganic complex form and micron/nano complex pore size.

Abstract: A liquid lens chip, a driving apparatus and a driving method thereof are provided. The driving apparatus includes a carrier and a driver. The carrier is configured to carry a liquid lens and has a plurality of electrode pairs in contact with the liquid lens. The driver provides a periodic first driving signal to a selected electrode pair of the electrode pairs during a first time period according to a scan control signal to change a shape of the liquid lens. The driver further provides a periodic second driving signal to an opposite electrode pair opposite to the selected electrode pair during a second time period to recover the shape of the liquid lens which has been changed during the first time period.

Abstract: A reactor suitable for a reaction containing an exothermic reaction is provided. The reactor includes the following components. A reaction channel has an inlet and an outlet, and has a front-end reaction zone, middle-end reaction zones, and a back-end reaction zone from the inlet to the outlet. A front-end catalyst support and a front-end catalyst are located in the front-end reaction zone, a middle-end catalyst support and a middle-end catalyst are respectively located in the middle-end reaction zones, and a back-end catalyst support and a back-end catalyst are located in the back-end reaction zone. The concentration of the front-end catalyst is less than the concentration of the back-end catalyst, and the concentration of the middle-end catalyst is decided via a computer simulation of reaction parameters. The reaction parameters include size and geometric shape of the reaction channel.

Abstract: A cell chip including first and second substrates and a dye dialysis layer disposed therebetween is provided. A cell-assembly region of the dye dialysis layer is disposed corresponding to a first hole of the first substrate, includes second holes and is configured to contain a sample solution containing cells. A size of the second hole is smaller than that of the cell. The cells are arranged on the cell-assembly region in a single layer manner. When a dye enters into the cell-assembly region via the first hole, the dye diffuses from the cell-assembly region to the micro-channel structure due to a concentration difference between the dye and a washing solution in the micro-channel structure. Thereby, the cells are dyed. Also, the washing solution passes in and out the cell chip via the second holes to accelerate the dye diffusion, and a high efficiency dynamic dialysis staining for cells is achieved.

Abstract: A drug carrier and a method of fabricating the same are provided. The drug carrier is used to cover boron-containing drugs. The drug carrier includes a negatively charged polysaccharide inner core and a positively charged polysaccharide outer shell. The negatively charged polysaccharide inner core covers the boron-containing drugs. The positively charged polysaccharide outer shell covers a surface of the negatively charged polysaccharide inner core. The drug carrier can be delivered and gathered near tumor tissues. Also, a leakage of the boron-containing drugs in the delivery process is low, so as to reduce damage to normal cells.

Abstract: A liquid lens chip, a driving apparatus and a driving method thereof are provided. The driving apparatus includes a carrier and a driver. The carrier is configured to carry a liquid lens and has a plurality of electrode pairs in contact with the liquid lens. The driver provides a periodic first driving signal to a selected electrode pair of the electrode pairs during a first time period according to a scan control signal to change a shape of the liquid lens. The driver further provides a periodic second driving signal to an opposite electrode pair opposite to the selected electrode pair during a second time period to recover the shape of the liquid lens which has been changed during the first time period.

Abstract: An image positioning and stitching method and an image detection system of a cell detection chip are provided. In the method, a moving path of an image capturing device for capturing images of the cell detection chip is planned according to a size of an imaging region of the image capturing device and a size of a detection region of the cell detection chip, wherein a plurality of marks for positioning the images are disposed in the detection region. Next, the image capturing device is controlled to move above the cell detection chip according to the planned moving path to capture a plurality of images of the cell detection chip. Lastly, the images are positioned and stitched into a complete chip image according to the positions of the marks appearing in the images.

Abstract: An apparatus for cell observation and a method for cell collection using the same are disclosed. The apparatus for cell selection comprises a first substrate having an opening; and a second substrate having a photoresist unit disposed on a surface thereof, wherein the photoresist unit comprises at least one notch and defines a space which is interconnected with the notch and corresponds to the opening of the first substrate.

Abstract: A non-enzymatic glucose biosensor and a manufacturing method thereof and a manufacturing method of a nanometal catalyst are provided. The non-enzymatic glucose biosensor includes a voltage source and a working electrode. The working electrode is electrically connected to the voltage source, wherein the working electrode includes a substrate and a nanometal catalyst. The nanometal catalyst is deposited on the substrate and includes polygonal block nanostructures, wherein the nanometal catalyst catalyzes the oxidation reaction of glucose.

Abstract: A metal ion detection equipment and a metal ion detection method are provided. The metal ion detection equipment includes a porous silicon resonant cavity structure, an electrochemical device and a spectrum detecting device. A sample solution permeates into the porous silicon resonant cavity structure. A to-be-detected metal ion of the sample solution in the porous silicon resonant cavity structure is reduced into a to-be-detected metal by the electrochemical device. The spectrum detecting device detects a spectral variation of a reflective light from the porous silicon resonant cavity structure.

Abstract: A hydrogen-generating device is provided, wherein a first substrate includes a liquid container and a first gas container at a first side thereof, and the first substrate sequentially includes a first and second liquid diffusion area and a diverging channel area from the liquid container to the first gas container. The first and second liquid diffusion areas respectively have a plurality of liquid diffusion structures, and the diverging channel area has a plurality of diverging channels. A laminate covers the first side of the first substrate and includes a liquid feed inlet connected to the liquid container. The first side of a second substrate covers the second side of the first substrate and includes a second gas container and a gas reaction channel located at the first side. A catalyst is disposed in the gas reaction channel and a heater is disposed on the second side of the second substrate.

Abstract: A visible light response photocatalyst structure and a process for manufacturing the same are disclosed, where the structure is manufactured by the GRR for two times, so that the structure has a large surface area, high surface activity, being apt to get integrated with a silicon substrate and endurable to the environment, and further has the rapid and simple manufacturing characteristics without any additional energy required and has a high reproductively.

Abstract: The present invention is related to a membrane electrochemical signal detection system, which comprises a detection platform and a probe, wherein the detection platform comprises a substrate having a cavity; a hydrogel layer disposed in the cavity of the substrate; and a carrier film disposed above the substrate and the hydrogel layer with at least one through hole corresponding to the cavity of the substrate as a sample slot. The surface of the probe is covered by an insulating layer and a metal for detection is exposed at a tip portion of the probe.

Abstract: The present invention provides a reparation method of a tubular vascular graft, (a) immersing a tubular scaffold in a first light sensitivity gelatin solution, and irradiate the tubular scaffold by a first time period, to let surface of the tubular scaffold form a base layer; (b) immersing the tubular scaffold of the step (a) in a chitin gelatin solution, when the surface of the base layer form a film, then immersing the tubular scaffold into a sodium hydroxide solution to generate a middle layer of the surface of the base layer; (c) immersing the tubular scaffold of the step (b) in a second light sensitivity gelatin solution, wherein the second light sensitivity gelatin solution comprises a cell, the tubular scaffold is irradiated by a second time period to form a surface layer of the middle layer; (d) until the cell forms a tubular structure of the surface layer by the cell in the tubular scaffold of the step (c), heating the tubular scaffold by a temperature to solve the base layer into a solution, pulling

Abstract: A reactor suitable for a reaction containing an exothermic reaction is provided. The reactor includes the following components. A reaction channel has an inlet and an outlet, and has a front-end reaction zone, middle-end reaction zones, and a back-end reaction zone from the inlet to the outlet. A front-end catalyst support and a front-end catalyst are located in the front-end reaction zone, a middle-end catalyst support and a middle-end catalyst are respectively located in the middle-end reaction zones, and a back-end catalyst support and a back-end catalyst are located in the back-end reaction zone. The concentration of the front-end catalyst is less than the concentration of the back-end catalyst, and the concentration of the middle-end catalyst is decided via a computer simulation of reaction parameters. The reaction parameters include size and geometric shape of the reaction channel.