Patents by Inventor Fang Shen

Fang Shen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10624536
    Abstract: A virtual reality-based ophthalmic inspection system includes a wearable unit, an electronic unit, and at least one detector; the wearable unit is available for an inspected object to wear the wearable unit on head; the electronic unit is assembled with the wearable unit and has a left-eye display zone and a right-eye display zone, wherein the left-eye display zone is used for displaying at least one left-eye sight-targets, and the right-eye display zone is used for displaying at least one right-eye sight-targets; the detector is disposed on the electronic unit. A sight-target with at least one distinguishing feature are shown on one of the left-eye display zone and the right-eye display zone, the left-eye display zone displays the sight-target while the right-eye display zone is filled with black, and the right-eye display zone displays the sight-target while the left-eye display zone is filled with black.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: April 21, 2020
    Inventors: Ho-Fang Shen, Ming-Fu Chen
  • Patent number: 10596173
    Abstract: The present invention is directed to compositions and methods for treating hepatitis B virus infection. In particular, the present invention is directed to a combination therapy comprising administration of an HBV capsid assembly inhibitor and an interferon for use in the treatment of hepatitis B virus infections.
    Type: Grant
    Filed: May 3, 2018
    Date of Patent: March 24, 2020
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Lu Gao, Isabel Najera, Hong Shen, Fang Shen, Liping Shi, Steffen Wildum, Guang Yang
  • Publication number: 20200010571
    Abstract: The present invention relates to bispecific anti-TNF-?/IL-17A antibodies and anti-TNF-? antibodies, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
    Type: Application
    Filed: September 11, 2019
    Publication date: January 9, 2020
    Inventors: Mark Chiu, Jennifer Nemeth-Seay, Tatiana Ort, Fang Shen
  • Publication number: 20190390162
    Abstract: Provided is a method for manufacturing cell-containing blocks having steps of: preparing an standardized size mold by 3D printing (three dimensional printing) using a biocompatible elastic material; injecting a thermosensitive colloid into the mold to form a thermosensitive mold; injecting a hydrogel containing cells in to the thermosensitive mold and curing the hydrogel containing cells to form the cell-containing blocks; separating the thermosensitive mold and the cell-containing blocks at a temperature higher than a solidifying point of the thermosensitive colloid. Also provided are method for assembling the cell-containing blocks in a target configuration by using an assembling mold defining the target configuration and made of a thermoreversible material.
    Type: Application
    Filed: June 20, 2019
    Publication date: December 26, 2019
    Inventors: Yu Fang Shen, Ming You Shie, Yi Wen Chen, Wei Huang Wang
  • Publication number: 20190381019
    Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the modulation of MALT 1. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, R5, and G, are defined herein.
    Type: Application
    Filed: June 13, 2019
    Publication date: December 19, 2019
    Inventors: Tianbao Lu, Peter J. Connolly, Maxwell David Cummings, Joseph Kent Barbay, Kevin D. Kreutter, Tongfei Wu, Gaston Stanislas Marcella Diels, Jan Willem Thuring, Ulrike Philippar, James Patrick Edwards, Fang Shen
  • Publication number: 20190152342
    Abstract: A power system for an electric vehicle comprising a battery pack connector unit and a battery assembly. The battery pack connector unit is electrically connected to a motor driver controller, and comprises at least a first battery connector and a second battery connector. The battery assembly includes at least a first battery pack and a second battery pack controlled by a first battery management system and a second battery management system respectively. When the first battery pack is electrically connected to the first battery connector, the first battery management system is arranged to become a master battery management system which is adapted to control the second battery management system as a slave battery management system, in such a manner that a respective voltage output of the battery assembly is optimally modulated by the master battery management system so as to create a single voltage output of the power system.
    Type: Application
    Filed: January 22, 2019
    Publication date: May 23, 2019
    Inventors: Fang SHEN, Hua SHUI, Jie CHEN
  • Publication number: 20190143833
    Abstract: This invention provides a method of computing dynamically the maximum power output to electric vehicle (EV) power train from the multiple and independently controlled battery packs to ensure safety and proper protection of the electric system. This method applies to an EV with multiple or extendable number of battery packs and provides fast computation of number of connected battery packs, the SOC of each battery pack, maximum power output of each battery pack and maximum power output of all battery packs combined.
    Type: Application
    Filed: November 12, 2017
    Publication date: May 16, 2019
    Inventors: Fang Shen, Hua Shui, Jie Chen
  • Publication number: 20180344148
    Abstract: A virtual reality-based ophthalmic inspection system includes a wearable unit, an electronic unit, and at least one detector; the wearable unit is available for an inspected object to wear the wearable unit on head; the electronic unit is assembled with the wearable unit and has a left-eye display zone and a right-eye display zone, wherein the left-eye display zone is used for displaying at least one left-eye sight-targets, and the right-eye display zone is used for displaying at least one right-eye sight-targets; the detector is disposed on the electronic unit. A sight-target with at least one distinguishing feature are shown on one of the left-eye display zone and the right-eye display zone, the left-eye display zone displays the sight-target while the right-eye display zone is filled with black, and the right-eye display zone displays the sight-target while the left-eye display zone is filled with black.
    Type: Application
    Filed: June 5, 2018
    Publication date: December 6, 2018
    Inventors: Ho-Fang SHEN, Ming-Fu CHEN
  • Publication number: 20180250301
    Abstract: The present invention is directed to compositions and methods for treating hepatitis B virus infection. In particular, the present invention is directed to a combination therapy comprising administration of an HBV capsid assembly inhibitor and an interferon for use in the treatment of hepatitis B virus infections.
    Type: Application
    Filed: May 3, 2018
    Publication date: September 6, 2018
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Lu Gao, Isabel Najera, Hong Shen, Fang Shen, Liping Shi, Steffen Wildum, Guang Yang
  • Publication number: 20180170909
    Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the modulation of MALT1. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, R5, R6, R5, G1, and G2 are defined herein.
    Type: Application
    Filed: December 20, 2017
    Publication date: June 21, 2018
    Inventors: Tianbao Lu, Brett Douglas Allison, Joseph Kent Barbay, Peter J. Connolly, Maxwell David Cummings, Gaston Diels, James Patrick Edwards, Kevin D. Kreutter, Ulrike Philippar, Fang Shen, Johannes Wilhelmus John Fitzgerald Thuring, Tongfei Wu
  • Publication number: 20180056805
    Abstract: This invention provides a method of energizing electric vehicle (EV) power train with multiple and independently controlled battery packs. In this method, an EV can have one or more battery packs installed, only limited by the EV's physical spaces of the battery pack connector. All battery packs are interchangeable. Each battery pack has its battery management system (BMS) software and can either provide energy to the EV concurrently or individually. A typical embodiment of the invention comprises of a battery pack controller, a battery pack connector, a battery pack acting as the master (master battery pack), and optional slave battery pack(s). The battery pack controller connects electronically with the battery pack connector. The master battery pack, and optional slave battery pack(s) are mounted in the modular battery pack connector.
    Type: Application
    Filed: August 27, 2016
    Publication date: March 1, 2018
    Inventors: Fang Shen, Hua Shui, Jie Chen
  • Patent number: 9879229
    Abstract: A method of using a cell to produce virus is provided involving growing cells under hyperosmotic conditions during a growth phase of the cells, infecting or transfecting the cells grown under hyperosmotic conditions with a virus, and maintaining the infected or transfected cells under less stressful conditions during a production phase of the infected or transfected cells to produce more of the virus. Viral productivity is improved by this method.
    Type: Grant
    Filed: February 15, 2012
    Date of Patent: January 30, 2018
    Assignee: National Research Council of Canada
    Inventors: Chun Fang Shen, Amine Kamen
  • Publication number: 20170218092
    Abstract: The present invention relates to bispecific anti-TNF-?/IL-17A antibodies and anti-TNF-? antibodies, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.
    Type: Application
    Filed: January 27, 2017
    Publication date: August 3, 2017
    Inventors: Mark Chiu, Jennifer Nemeth-Seay, Tatiana Ort, Fang Shen
  • Publication number: 20170108243
    Abstract: A tile or plate, includes: an upper plate (3) and a lower plate (4); wherein a plurality of heat conducting cavities (6) are uniformly provided between the upper plate (3) and the lower plate (4) via connecting ribs (5). A solar collection layer is provided on an upper surface of the tile or the plate. Two ends of the tile or the plate are connected with each of the plurality of the heat conducting cavities (6) via transverse connecting pipes (23, 37, 42). The transverse connecting pipes (23, 37, 42) of two neighboring tiles are connected by a ferrule (17) or a hose (36) to form an integrated circulation system. The tile or plate has a large day-lighting area and a high energy conversion rate.
    Type: Application
    Filed: July 24, 2014
    Publication date: April 20, 2017
    Inventors: Yunliang Qu, Jian Cui, Zhixiang Ying, Fang Shen, Bin Qu, Xinrong Wang, Chen Zhang, Xiangdong Li, Hongxing Wang
  • Publication number: 20160134147
    Abstract: The invention relates to a battery energy storage system (10) and controlling method, wherein the battery energy storage system comprising: an input (102) capable of connecting with a grid; a first output (104) capable of connecting with a first load; a charge controller (108) connected to the input (102) and adapted to convert an alternating current power supply from the input (102) to a direct current power supply; a battery (110) connected to the charge controller (108) and adapted to store the direct current power supply converted by the charge controller (108); an inverter (112) connected to the battery (110) and the first output (104) and adapted to convert a direct current power supply stored in the battery (110) to an alternating current power supply and output the converted alternating current power supply to the first output (104); a first switch (114) connected to the input (102) and the first output (104); and an energy management system (118) adapted to control the charge controller (108), the in
    Type: Application
    Filed: June 13, 2013
    Publication date: May 12, 2016
    Inventors: Fang Shen, Jie Chen
  • Patent number: 8875083
    Abstract: Disclosed herein are rouging methods and devices for a flip-chip package. The flip chip includes several outer pads and several inner pads. The routing method includes: setting an outer sequence based on the arrangement order of the outer pads; setting several inner sequences based on the connection relationships between inner pads and the outer pads; calculating the longest common subsequence of each inner sequence and the outer sequence, defining the connection relationships between the inner pads and the outer pads corresponding to the longest common subsequence as direct connections, and defining the connection relationships between the inner pads and the outer pads that do not correspond to the longest common subsequence as detour connections; establishing the routing scheme of the flip chip based on the connection relationships between the inner pads and the outer pads.
    Type: Grant
    Filed: October 3, 2013
    Date of Patent: October 28, 2014
    Assignee: Synopsys, Inc.
    Inventors: Chen-Feng Chang, Chin-Fang Shen, Hsien-Shih Chiu, I-Jye Lin, Tien-Chang Hsu, Yao-Wen Chang, Chun-Wei Lin, Po-Wei Lee
  • Publication number: 20140137959
    Abstract: A fuel supply device connects a fuel tank, which stores a fuel necessary for power of an engine, to a hand-operating pump inlet of the engine, connects an inlet opening of a filter can that includes the inlet opening and an outlet opening to a hand-operating pump outlet of the engine, connects the outlet opening to a slope terminal of a fuel-returning three-way pipe, connects a priority terminal of the fuel-returning three-way pipe to a fuel return port of the engine, and connects a discharge terminal of the fuel-returning three-way pipe to a high-pressure pump fuel inlet port of the engine, whereby heated fuel from the fuel return port of the engine is supplied, with priority, through the discharge terminal of the fuel-returning three-way pipe to the engine for combustion for saving energy and effectively improving operation performance of the engine.
    Type: Application
    Filed: November 5, 2013
    Publication date: May 22, 2014
    Applicant: SHEN'S GLORY INC.
    Inventor: WU-FANG SHEN
  • Publication number: 20140033156
    Abstract: Disclosed herein are rouging methods and devices for a flip-chip package. The flip chip includes several outer pads and several inner pads. The routing method includes: setting an outer sequence based on the arrangement order of the outer pads; setting several inner sequences based on the connection relationships between inner pads and the outer pads; calculating the longest common subsequence of each inner sequence and the outer sequence, defining the connection relationships between the inner pads and the outer pads corresponding to the longest common subsequence as direct connections, and defining the connection relationships between the inner pads and the outer pads that do not correspond to the longest common subsequence as detour connections; establishing the routing scheme of the flip chip based on the connection relationships between the inner pads and the outer pads.
    Type: Application
    Filed: October 3, 2013
    Publication date: January 30, 2014
    Applicant: SYNOPSYS, INC.
    Inventors: Chen-Feng Chang, Chin-Fang Shen, Hsien-Shih Chiu, I-Jye Lin, Tien-Chang Hsu, Yao-Wen Chang, Chun-Wei Lin, Po-Wei Lee
  • Publication number: 20140004568
    Abstract: A method of using a cell to produce virus is provided involving growing cells under hyperosmotic conditions during growth phase of the cells, infecting or transfecting the cells grown under hyperosmotic conditions with a virus, and maintaining the infected or transfected cells under less stressful conditions during a production phase of the infected or transfected cells to produce more of the virus. Viral productivity is improved by this method.
    Type: Application
    Filed: February 15, 2012
    Publication date: January 2, 2014
    Applicant: National Research Council of Canada
    Inventors: Chun Fang Shen, Amine Kamen
  • Publication number: 20130302886
    Abstract: The invention provides isolated Pre-Ligand Assembly Domain (PLAD) polypeptides which inhibit multimerization of a receptor complex comprising an IL-17R family member. Related PLAD-binding polypeptides, chimeric proteins, conjugates, nucleic acids, vectors, host cells, and methods are provided herein.
    Type: Application
    Filed: May 8, 2013
    Publication date: November 14, 2013
    Applicants: RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK, AMGEN INC.
    Inventors: Sarah L. GAFFEN, Fang Shen, Walter Hanel, Jill Kramer, James P. Malone, Michael Wittekind, Raymond Paxton